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| 1 | 慢性腰背痛患者的大脑灰质异常:基于体素的形态测量学分析显示文摘目的探讨慢性腰背痛患者大脑灰质的形态学变化。方法选择30例慢性腰背痛患者和30例健康志愿者,行3.0T磁共振扫描,获得高分辨T1结构像数据并用FMRIB软件库中的基于体素的形态学分析方法进行数据处理和统计学分析,获得疼痛组和健康组之间大脑灰质的形态学差异信息。结果与健康志愿者相比较,慢性腰背痛患者大脑皮层多个脑区灰质体积减少,包括双侧额上回、右侧额极、左侧岛叶、左侧颞下回及左侧颞中回(P<0.05,TFCE校正后);皮层下多个灰质核团体积增加,包括左侧丘脑、双侧壳核、双侧伏隔核、右侧尾状核(P<0.05,TFCE校正后)。结论慢性腰背痛患者大脑皮层和皮层下灰质存在不同的改变模式,这种变化可能与大脑对慢性疼痛的适应不良有关。 | 毛翠平 杨全新 唐鉴 杨花娟 白芝兰 张秋娟 Zahid Nadeem | 2016 | 南方医科大学学报2016，36，8： | 4 |
| 2 | 2型糖尿病患者大脑后扣带回谷氨酸代谢的磁共振波谱研究显示文摘目的 探讨2型糖尿病(T2DM)患者大脑后扣带回谷氨酸代谢变化及其与血糖的关系,以了解糖尿病脑病病理生理变化的物质基础。方法 连续收集15例T2DM患者和10例健康志愿者,采用TE-averaged PRESS序列行MRS检查,比较2组间大脑后扣带回谷氨酸(Glu)、N-乙酰天门冬氨酸( NAA)、乙酰胆碱(Cho)和肌酸(Cr)水平差异,分析代谢物与血糖水平之间的关系。结果 与对照组相比,T2DM组大脑后扣带回Cho(P=0.02)及Glu(P〈0.01)含量显著升高,NAA含量显著降低(P=0.03),而Cr在2组间无显著差异(P>0.05)。在对照组和T2DM组,糖化血红蛋白(HbA1c)与Glu之间呈显著正相关(r=0.692,P=0.000),而糖化血红蛋白与NAA呈显著的负相关(r=-0.628,P=0.001)。结论 采用TE-averaged PRESS序列可测定T2DM患者大脑后扣带回脑区代谢物水平的变化,尤其是可以独立测量Glu含量,并发现Glu升高和NAA下降与高血糖有关。 | 张秋娟 戴晓庆 宫琰 白芝兰 李小会 ZAHID NADEEM 何娜 | 2016 | 实用放射学杂志2016，32，9： | 4 |
| 3 | MRI在垂体腺瘤术前质地判断中的预测价值显示文摘目的探讨MRI信号强度与垂体腺瘤(PA)质地的相关性及其对质地的预测价值。方法47例经手术病理证实的PA患者根据质地分为2组:质软组37例,质韧组10例。比较2组患者的T1WI、T2WI相对信号强度及动态增强参数[信号增强率(SER)],分析信号强度和动态增强参数与质地之间的关系。结果2组间PA的T2信号强度[T2PA/T2脑白质(WM)、T2PA/T2脑灰质(GM)、T2PA/T2脑脊液(CSF)]及SER有显著的统计学差异(P<0.05):质软组显著高于质韧组;2组间T1信号强度[T1PA/T1脑桥(PN)]无显著统计学差异(P>0.05)。绘制T2PA/T2WM、T2PA/T2GM、T2PA/T2CSF、T1PA/T1PN及SER对PA质地的预测ROC曲线,结果显示:AUC分别为0.857、0.835、0.856、0.630、0.781,其中T2PA/T2WM的AUC最大(P<0.05)。结论MRIT2信号强度与PA质地有关,T2PA/T2WM、T2PA/T2GM、T2PA/T2CSF可作为判断PA质地的指标。 | 同斯平 张秋娟 Zahid Nadeem 刘重霄 李小会 | 2019 | 实用放射学杂志2019，35，3： | 3 |
| 4 | Prevalence of hepatitis B and C in internally displaced persons of war against terrorism in Swat, Pakistan显示文摘 | Abdul Rauf Muhammad Shahid Nadeem Akbar Ali Muhammad Iqbal Muhammad Mustafa Muhammad Muzammal Latif Muhammad Zahid Latif Nisar Ahmed Abdul Rauf Shakoori | 2011 | The European Journal of Public Health2011，，： | 1 |
| 5 | Weed control through allelopathic crop water extracts and S-metolachlor in cotton显示文摘Weeds are one of the most important biological constraint to cotton production,and result-ing in a yield losses of up to 90%.The evolution of hundreds of resistant weed species,the lack of new herbicide chemistries,and the increase in weed management costs are all mak-ing weed management more arduous for the growers.Hence,a field experiment was con-ducted to investigate the efficacy of allelopathic crop water extracts(ACWEs)alone and in combinaton with one third rate of S-metolachlor 717g ai.ha-1for effective weed man-agement in cotton.The treatments investigated were;weedy check,sorghum+brassica water extract(WE)at 1.5Lha 1,sorghum+sunflower WE at 1.5Lha-,sorghum+bras-sica+sunflower WE at 1.5Lha-1,sorghum+brassica WE at 15L ha-1+S-metolachlor at 717 g a.i.ha-l,sorghum+sunflower WE at 1.5L ha-1+S-metolachlor at 717 g a.i.ha-1,sor-ghum+brassica WE+sunflower WE at 1.5Lha-1+S-metolachlor at 717 gaiha-,and S-metolachlor at recommended rate of 2.15 kg ai.ha-1.Results revealed that pre-emergent application of sorghum+brassica water extract(WE)at 1.5L ha-1 was the best treatment in terms of effective dry biomass reduction(40%)of Trianthema portulacastrum and Cyperus rotundus,and increase in seed cotton yield(12%).The second best treatment was sorghum+sunflower WE at 1.5Lha-1+S-metolachlor at 717g ai.ha-1 with yield increase of 11%over the weedy control.In comparison,S-metolachlor at recommended rate 2.15kg a.i.ha-1 recorded only 4%decrease in weeds dry biomass reduction and 8%increase in seed cotton yield.Hence,it can be predicted that binary combinaton of sorghum and brassica WE at 1.5 Lha-1 or binary combination of sorghum+sunflower WE at 15Lha-1 with one third dose of S-metolachlor (717g aiha-l)can be used for effective weed management and increase in seed cotton yield.Furthermore,adoption of this technique will also reduce the herbicide application,which is not only benefcial for the ecosystem but,also minimize the evolution of herbicide-resistant weed species. | Nadeem Iqbal Abdul Khaliq Zahid Ata Cheema | 2020 | Information Processing in Agriculture2020，7，1： | 1 |
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