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| 1 | Impacts of temperature and precipitation on runoff in the Tarim River during the past 50 years显示文摘The relationship between climate change and water resources in the Tarim River was analyzed by combining the temperature,precipitation and streamflow data from 1957 to 2007 from the four headstreams of the Tarim River (Aksu,Hotan,Yarkant and Kaidu rivers) in the study area.The long-term trend of the hydrological time series including temperature,precipitation and streamflow were studied using correlation analysis and partial correlations analysis.Holt double exponential smoothing was used to fit the trends between streamflow and the two climatic factors of Aksu River,Hotan River and Yarkant River.The streamflow of the main stream was forecasted by Autoregressive Integrated Moving Average Model (ARIMA) modeling by the method of time series analysis.The results show that the temperature experienced a trend of monotonic rising.The precipitation and runoff of the four headstreams of the Tarim River increased,while the inflow to the headstreams increased and the inflow into the Tarim River decreased.Changes of temperature and precipitation had a significant impact on runoff into the four headstreams of the Tarim River: the precipitation had a positive impact on water flow in the Aksu River,Hotan River and Kaidu River,while the temperature had a positive impact on water flow in the Yarkant River.The results of Holt double exponential smoothing showed that the correlation between the independent variable and dependent variable was relatively close after the model was fitted to the headstreams,of which only the runoff and temperature values of Hotan River showed a significant negative correlation.The forecasts by the ARIMA model for 50 years of annual runoff at the Allar station followed the pattern of the measured data for the same years.The short-term forecasts beyond the observed series adequately captured the pattern in the data and showed a decreasing tendency in the Tarim River flow of 3.07% every ten years.The results showed that global warming accelerated the water recharge process of the headstreams.The special hydrological characteristics of the arid area determined the significant association between streamflow and the two climatic factors studied.Strong glacier retreat is likely to bring a series of flood disasters within the study area. | YuTing FAN YaNing CHEN WeiHong LI HuaiJun WANG XinGong LI | 2011 | Journal of Arid Land2011，3，3： | 13 |
| 2 | Hydrological and water cycle processes of inland river basins in the arid region of Northwest China显示文摘The increasing shortage in water resources is a key factor affecting sustainable socio-economic development in the arid region of Northwest China(ARNC). Water shortages also affect the stability of the region's oasis ecosystem. This paper summarizes the hydrological processes and water cycle of inland river basins in the ARNC, focusing on the following aspects: the spatial-temporal features of water resources(including air water vapor resources, runoff, and glacial meltwater) and their driving forces; the characteristics of streamflow composition in the inland river basins; the characteristics and main controlling factors of baseflow in the inland rivers; and anticipated future changes in hydrological processes and water resources. The results indicate that:(1) although the runoff in most inland rivers in the ARNC showed a significant increasing trend, both the glaciated area and glacial ice reserves have been reduced in the mountains;(2) snow melt and glacier melt are extremely important hydrological processes in the ARNC, especially in the Kunlun and Tianshan mountains;(3) baseflow in the inland rivers of the ARNC is the result of climate change and human activities, with the main driving factors being the reduction in forest area and the over-exploitation and utilization of groundwater in the river basins; and(4) the contradictions among water resources, ecology and economy will further increase in the future. The findings of this study might also help strengthen the ecological, economic and social sustainable development in the study region. | CHEN Yaning LI Baofu FAN Yuting SUN Congjian FANG Gonghuan | 2019 | Journal of Arid Land2019，11，2： | 12 |
| 3 | A novel preparation of nanosized hexagonal Mg(OH)2 as a flame retardant显示文摘 | Yongbin Chen Tao Zhou Huaxiong Fang Simin Li Yuting Yao Bailin Fan Jian Wang | 2016 | Particuology2016，14，1： | 10 |
| 4 | Oncogenic AURKA-enhanced N6-methyladenosine modification increases DROSHA mRNA stability to transactivate STC1 in breast cancer stem-like cells显示文摘RNase III DROSHA is upregulated in multiple cancers and contributes to tumor progression by hitherto unclear mechanisms.Here,we demonstrate that DROSHA interacts withβ-Catenin to transactivate STC1 in an RNA cleavage-independent manner,contributing to breast cancer stem-like cell(BCSC)properties.DROSHA mRNA stability is enhanced by N6-methyladenosine(m^(6)A)modification which is activated by AURKA in BCSCs.AURKA stabilizes METTL14 by inhibiting its ubiquitylation and degradation to promote DROSHA mRNA methylation.Moreover,binding of AURKA to DROSHA transcript further strengthens the binding of the m^(6)A reader IGF2BP2 to stabilize m^(6)A-modified DROSHA.In addition,wild-type DROSHA,but not an m^(6)A methylation-deficient mutant,enhances BCSC stemness maintenance,while inhibition of DROSHA m^(6)A modification attenuates BCSC traits.Our study unveils the AURKA-induced oncogenic m^(6)A modification as a key regulator of DROSHA in breast cancer and identifies a novel DROSHA transcriptional function in promoting the BCSC phenotype. | Fei Peng Jie Xu Bai Cui Qilan Liang Sai Zeng Bin He Hong Zou Manman Li Huan Zhao Yuting Meng Jin Chen Bing Liu Shasha Lv Peng Chu Fan An Zifeng Wang Junxiu Huang Yajing Zhan Yuwei Liao Jinxin Lu Lingzhi Xu Jin Zhang Zhaolin Su Zhiguang Li Fangjun Wang Eric W-FLam Quentin Liu | 2021 | Cell Research2021，31，3： | 9 |
| 5 | Performance Analysis of WLAN Medium Access Control Protocols in Simulcast Radio-Over-Fiber-Based Distributed Antenna Systems显示文摘The performance of three wireless local-area network(WLAN) media access control(MAC) protocols is investigated and compared in the context of simulcast radioover-fiber-based distributed antenna systems(RoF-DASs) where multiple remote antenna units(RAUs) are connected to one access point(AP) with different-length fiber links.The three WLAN MAC protocols under investigation are distributed coordination function(DCF) in basic access mode,DCF in request/clear to send(RTS/CTS) exchange mode,and point coordination function(PCF).In the analysis,the inter-RAU hidden nodes problems and fiber-length difference effect are both taken into account.Results show that adaptive PCF mechanism has better throughput performances than the other two DCF modes,especially when the inserted fiber length is short. | LI Jianqiang FAN Yuting CHEN Hao LU Xun XU Kun | 2014 | China Communications2014，11，5： | 5 |
| 6 | Enhancement of Bio-based para-Xylene Selectivity in Catalytic Fast Pyrolysis of Cellulose Using a Surface-modified Mg/P/HZSM-5 Catalyst显示文摘With the growing consumption of oil, the production of /?-xylene(PX) from renewable biomass has gained significant attention recently. This work demonstrated that cellulose, a main component in lignocellulosic biomass, was directly converted into PX over the Mg/P surface-modified zeolites. The catalysts modified by the incorporation of P2O5 and MgO into HZSM-5(HZ) promoted the isomerization of zw-/o-xylenes to p-xylene. The PX selectivity was greatly enhanced using the modified zeolites due to the deactivation of external surface and the adjustment of pore entrance. In addition, the addition of methanol to cellulose was beneficial to increase the selectivity of xylenes due to the alkylation reactions and the Diels-Alder reactions between cellulose-derived furans and methanol-derived olefins. The highest PX yield of 10.7%(molar fraction) with a high PX selectivity in xylenes(97.1%) was obtained over the 10%Mg/5%P/HZ catalyst. The reaction pathway for the formation ofp-xylene was addressed according to the study of the key reactions and the characterization of catalysts. | WANG Yulan FAN Minghui ZHU Lijuan WANG Shengfei HE Yuting LI Quanxin | 2019 | Chemical Research in Chinese Universities2019，35，3： | 4 |
| 7 | Fabricating antibacterial CoCrCuFeNi high-entropy alloy via selective laser melting and in-situ alloying显示文摘A quasi-equiatomic CoCrFeCuNi high-entropy alloy(HEA) with a broad-spectrum antibacterial ability and good mechanical properties has been fabricated by selective laser melting(SLM) and in-situ alloying of a blend of pre-alloyed CoCrFeNi powder and Cu elemental powder.The as-built HEA alloy has a homogeneous distribution of Cu and presents a single FCC phase.Compared with the same HEA fabricated using the traditional ingot metallurgy(IM) process,the HEA alloy fabricated by SLM releases more Cu ions to prevent growth and biofilm formation by gram-negative Escherichia coli and gram-positive Staphylococcus aureus,which enhances the applicability of the HEA alloy in potential applications that requires antibacterial ability.The results of this study confirm the feasibility of combining the antibacterial CoCrFeCuNi HEA alloy and SLM technology in fabricating complex shaped parts or structures with a strong antibacterial ability to be used in medical application or other environments desired for antibacterial ability. | Jingbo Gao Yuting Jin Yongqiang Fan Dake Xu Lei Meng Cong Wang Yuanping Yu Deliang Zhang Fuhui Wang | 2022 | Journal of Materials Science & Technology2022，，7： | 4 |
| 8 | Identification and differentiation of major components in three different “Sheng-ma” crude drug species by UPLC/Q-TOF-MS显示文摘Cimicifugae Rhizoma(Sheng ma) is a Ranunculaceae herb belonging to a composite family and well known in China,has been widely used in traditional Chinese medicine.The Pharmacopoeia of the People's Republic of China contains three varieties(Cimicifuga dahurica(Turcz.),Cimicifuga foetida L.and Cimicifuga heracleifolia Kom.) which have been used clinically as 'Sheng-ma'.However,the chemical constituents of three components of 'Sheng-ma' have never been documented.In this study,a rapid method for the analysis of the main components of 'Sheng-ma' was developed using ultra-high performance liquid chromatography with quadrupole-time-of-flight mass spectrometry(UPLC/Q-TOF-MS).The present study reveals the major common and distinct chemical constituents of C.dahurica,C.foetida and C.heracleifolia and also reports principal component and statistical analyses of these results.The components were identified by comparing the retention time,accurate mass,mass spectrometric fragmentation characteristic ions and matching empirical molecular formula with that of the published compounds.A total of 32 common components and 8 markers for different 'Sheng-ma' components were identified.These findings provide an important basis for the further study and clinical utilities of the three 'Sheng-ma' varieties. | Mengxue Fan Kunming Qin Fei Ding Yuting Huang Xiaoli Wang Baochang Cai | 2017 | Acta Pharmaceutica Sinica B2017，7，2： | 4 |
| 9 | A Detection-Switching-Assisted DCF Mechanism for Simulcast WLAN-over-Fiber Based Distributed Antenna Systems显示文摘Distributed antenna systems(DASs) using Radio-over-fiber(Ro F) links is a promising candidate to provide flexible coverage and high data rates. For simulcast Wireless local-area network(WLAN) use in Ro F systems, the stations covered by different Remote antenna units(RAUs) contend for the wireless medium using Media access control(MAC) mechanism. Severe inter-RAU hidden nodes problem will happen due to the stations in different RAUs cannot detect each other very well. In order to alleviate this inter-RAU collision problem, a promising detection-switching-assisted Distributed coordination function(DCF) mechanism is presented using in the uplink. The control delay issues of the proposed mechanism are also discussed in this paper. | FAN Yuting LI Jianqiang XU Kun DAI Yitang | 2017 | Chinese Journal of Electronics2017，26，4： | 3 |
| 10 | A male-ABCD algorithm for hepatocellular carcinoma risk prediction in HBs Ag carriers显示文摘Objective: Hepatocellular carcinoma(HCC) development among hepatitis B surface antigen(HBs Ag) carriers shows gender disparity, influenced by underlying liver diseases that display variations in laboratory tests. We aimed to construct a risk-stratified HCC prediction model for HBs Ag-positive male adults.Methods: HBs Ag-positive males of 35-69 years old(N=6,153) were included from a multi-center populationbased liver cancer screening study. Randomly, three centers were set as training, the other three centers as validation. Within 2 years since initiation, we administrated at least two rounds of HCC screening using Bultrasonography and α-fetoprotein(AFP). We used logistic regression models to determine potential risk factors,built and examined the operating characteristics of a point-based algorithm for HCC risk prediction.Results: With 2 years of follow-up, 302 HCC cases were diagnosed. A male-ABCD algorithm was constructed including participant's age, blood levels of GGT(γ-glutamyl-transpeptidase), counts of platelets, white cells,concentration of DCP(des-γ-carboxy-prothrombin) and AFP, with scores ranging from 0 to 18.3. The area under receiver operating characteristic was 0.91(0.90-0.93), larger than existing models. At 1.5 points of risk score,26.10% of the participants in training cohort and 14.94% in validation cohort were recognized at low risk, with sensitivity of identifying HCC remained 100%. At 2.5 points, 46.51% of the participants in training cohort and 33.68% in validation cohort were recognized at low risk with 99.06% and 97.78% of sensitivity, respectively. At 4.5 points, only 20.86% of participants in training cohort and 23.73% in validation cohort were recognized at high risk,with positive prediction value of 22.85% and 12.35%, respectively.Conclusions: Male-ABCD algorithm identified individual's risk for HCC occurrence within short term for their HCC precision surveillance. | Yuting Wang Minjie Wang He Li Kun Chen Hongmei Zeng Xinyu Bi Zheng Zhu Yuchen Jiao Yong Wang Jian Zhu Hui Zhao Xiang Liu Chunyun Dai Chunsun Fan Can Zhao Deyin Guo Hong Zhao Jianguo Zhou Dongmei Wang Zhiyuan Wu Xinming Zhao Wei Cui Xuehong Zhang Jianqiang Cai Wanqing Chen Chunfeng Qu | 2021 | Chinese Journal of Cancer Research2021，33，3： | 3 |
| 11 | Sandwiching Sulfur into the Dents Between N,O Co-Doped Graphene Layered Blocks with Strong Physicochemical Confinements for Stable and High-Rate Li-S Batteries显示文摘The development of lithium-sulfur batteries(LSBs)is restricted by their poor cycle stability and rate performance due to the low conductivity of sulfur and severe shuttle effect.Herein,an N,O co-doped graphene layered block(NOGB)with many dents on the graphene sheets is designed as effective sulfur host for high-performance LSB s.The sulfur platelets are physically confined into the dents and closely contacted with the graphene scaffold,ensuring structural stability and high conductivity.The highly doped N and O atoms can prevent the shuttle effect of sulfur species by strong chemical adsorption.Moreover,the micropores on the graphene sheets enable fast Li^+transport through the blocks.As a result,the obtained NOGB/S composite with 76 wt%sulfur content shows a high capacity of 1413 mAh g^-1 at 0.1 C,good rate performance of 433 mAh g^-1 at 10 C,and remarkable stability with 526 mAh g^-1 at after 1000 cycles at 1 C(average decay rate:0.038%per cycle).Our design provides a comprehensive route for simultaneously improving the conductivity,ion transport kinetics,and preventing the shuttle effect in LSBs. | Mengjiao Shi Su Zhang Yuting Jiang Zimu Jiang Longhai Zhang Jin Chang Tong Wei Zhuangjun Fan | 2020 | Nano-Micro Letters2020，12，11： | 3 |
| 12 | Nutritional properties of Europen eel(Anguilla anguilla)bone peptide-calcium and its apoptosis effect on Caco-2 cells显示文摘The present study aimed at making a rational usage for European eel bone by-products by preparing Europen eel bone peptide chelated calcium(EBPC-Ca).Nutritional properties and bioactivity of EBPC-Ca were evaluated.Results showed that nutritional properties of calcium ions will cause intra-and inter-molecular folding and aggregation of peptide to uniformly form EBPC-Ca chelate.The chelated compound of EBPC and calcium ion triggered a strong apoptosis in heterogeneous human epithelial colorectal adenocarcinoma(Caco-2)in concentration-and time-dependent manners.Western blot analysis revealed that the EBPC-Ca induced apoptosis may be the result of a blocked autophagy flux through mitochondrial-dependent pathway.Additionally,the increase in FGF-23 protein expression inhibited the absorption of calcium ions and alleviated cell apoptosis.It was also found that the cell apoptosis occurs with significant increases in the levels of reactive oxygen species(ROS)and Ca^(2+)in the cells,indicating the anti-tumor potential of EBPC-Ca may involve multiple channels. | Hui Teng Yuewei Qian Xiaoyun Fan Hui Cao Yuting Tian Lei Chen | 2022 | Food Science and Human Wellness2022，11，6： | 3 |
| 13 | Five novel transition metal coordination polymers with 2D/3D framework structure based on flexible H2 tzda and ancillary ligand bpe显示文摘 | Wang Yuting Xu Yan Fan Yaoting | 2009 | J Solid State Chem2009，182，10： | 1 |
| 14 | Metal-organic coordination polymers assembled from divalent transition salts with a flexible spacer ligand: hydrothermal syntheses, crystal structures, and luminescent and magnetic properties显示文摘 | Wang Yuting Shen Xiaoqing Fan Yaoting | 2008 | Supramol Chem2008，20，5： | 1 |
| 15 | Advances in Researches on Genetic Diversity of Lepidoptera Insects显示文摘This paper reviewed advances in researches on genetic diversity of Lepidoptera insects from chromosome polymorphism,protein polymorphism,and DNA polymorphism,and stated that DNA sequence variation will become main points of researches about genetic diversity. | Yuting WANG Ruixue LI Fan SUN Wei WANG Taichu WANG | 2017 | Asian Agricultural Research2017，9，4： | 1 |
| 16 | Secure K-Nearest neighbor queries in two-tiered mobile wireless sensor networks显示文摘Tiered Mobile Wireless Sensor Network(TMWSN)is a new paradigm introduced by mobile edge computing.Now it has received wide attention because of its high scalability,robustness,deployment flexibility,and it has a wide range of application scenarios.In TMWSNs,the storage nodes are the key nodes of the network and are more easily captured and utilized by attackers.Once the storage nodes are captured by the attackers,the data stored on them will be exposed.Moreover,the query process and results will not be trusted any more.This paper mainly studies the secure KNN query technology in TMWSNs,and we propose a secure KNN query algorithm named the Basic Algorithm For Secure KNN Query(BAFSKQ)first,which can protect privacy and verify the integrity of query results.However,this algorithm has a large communication overhead in most cases.In order to solve this problem,we propose an improved algorithm named the Secure KNN Query Algorithm Based on MR-Tree(SEKQAM).The MR-Trees are used to find the K-nearest locations and help to generate a verification set to process the verification of query results.It can be proved that our algorithms can effectively guarantee the privacy of the data stored on the storage nodes and the integrity of the query results.Our experimental results also show that after introducing the MR-Trees in KNN queries on TMWSNs,the communication overhead has an effective reduction compared to BAFSKQ. | Lihong Fan Liang Liu Hang Gao Zuchao Ma Yuting Wu | 2021 | Digital Communications and Networks2021，7，2： | 1 |
| 17 | Enhanced therapeutic efficacy of vitamin K2 by silencing BCL-2 expressionin SMMC-7721 hepatocellular carcinoma cells显示文摘 | Yuting Yao Lu Li He Zhang Renbing Jia Bo Liu Xiaoping Zhao Leilei Zhang Guanxiang Qian Xianqun Fan Shengfang Ge | 2012 | Oncology Letters2012，，1： | 1 |
| 18 | Five novel transition metal coordination polymers with 2D/3D framework structure based on flexible H2tzda and ancillary ligand bpe显示文摘 | Wang Yuting Xu Yan Fan Yaoting | 2009 | J Solid State Chem2009，182，10： | 1 |
| 19 | Identification of Potential Therapeutic Targets of Alzheimer's Disease By Weighted Gene Co-Expression Network Analysis显示文摘Objective Alzheimer's disease(AD)is the most common cause of dementia.The pathophysiology of the disease mostly remains unearthed,thereby challenging drug development for AD.This study aims to screen high throughput gene expression data using weighted co-expression network analysis(WGCNA)to explore the potential therapeutic targets.Methods The dataset of GSE36980 was obtained from the Gene Expression Omnibus(GEO)database.Normalization,quality control,filtration,and soft-threshold calculation were carried out before clustering the co-expressed genes into different modules.Furthermore,the correlation coefiidents between the modules and clinical traits were computed to identify the key modules.Gene ontology and pathway enrichment analyses were performed on the key module genes.The STRING database was used to construct the protein-protein interaction(PPI)networks,which were further analyzed by Cytoscape app(MCODE).Finally,validation of hub genes was conducted by external GEO datasets of GSE 1297 and GSE 28146.Results Co-expressed genes were clustered into 27 modules,among which 6 modules were identified as the key module relating to AD occurrence.These key modules are primarily involved in chemical synaptic transmission(G0:0007268),the tricarboxylic acid(TCA)cycle and respiratory electron transport(R-HSA-1428517).WDR47,OXCT1,C3orfl4,ATP6V1A,SLC25A14,NAPB were found as the hub genes and their expression were validated by external datasets.Conclusions Through modules co-expression network analyses and PPI network analyses,we identified the hub genes of AD,including WDR47,0XCT1,C3orfl4i ATP6V1A,SLC25A14 and NAPB.Among them,three hub genes(ATP6V1A,SLC25A14,OXCT1)might contribute to AD pathogenesis through pathway of TCA cycle. | Fan Zhang Siran Zhong Siman Yang Yuting Wei Jingjing Wang Jinlan Huang Dengpan Wu Zhenguo Zhong | 2020 | Chinese Medical Sciences Journal2020，35，4： | 1 |
| 20 | Monodisperse micro-spherical Sr_(2-z)Mg_(1+y)Y_(z)Al_(22-x)O_(36):xMn^(4+)red phosphors显示文摘With narrow red photoluminescence (PL) bands, tetravalent Mn^(4+) doped phosphors show promising prospect in commercial application to effectively expand color gamut of phosphor converted LED displays. Here, we report a type of Sr_(2-z)Mg_(1+y)Y_(z)Al_(22-x)O_(36):xMn^(4+) phosphors with regular cage-like micro-spherical morphologies. The micron size spherical precursors were synthesized with a propylene oxide (PO) driven fast sol–gel method. The cage -like spherical morphology is beneficial to efficiently trapping much incident light to enhance the PL of the phosphors. Being calcined at 1300 ℃, Sr_(2)MgAl_(21.978)O_(36):0.022Mn^(4+) only exhibits the internal quantum efficiency (IQE) of 24.91%. With the Mg^(2+)-Mn^(4+) codoping and Y^(3+)/Sr^(2+) substituting strategies, to fulfill charge balance and produce John-Teller distortion, IQE of Sr_(2-z)Mg_(1+y)Y_(z)Al_(22-x)O_(36):xMn^(4+) can be further improved up to 36.45%. The CIE color coordinates of Sr_(2-z)Mg_(1+y)Y_(z)Al_(22-x)O_(36):xMn^(4+) under near ultraviolet excitation can be stably fixed to (0.723, 0.227) at deep red region. It thus finds a potential application as pc-LED display with much broader color gamut than that of the NTSC standard. Therefore, Sr_(2-z)Mg_(1+y)Y_(z)Al_(22-x)O_(36):xMn^(4+) micron size spheres can be employed as promising red phosphors for high performance LED displays. | Jiannan Jia Mengting He Jun Wan Yuting Zhang Hai Guo Xianping Fan Xusheng Qiao Shiguo Chen | 2022 | Journal of Rare Earths2022，40，4： | 1 |
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