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| 1 | Cancer models in preclinical research:A chronicle review of advancement in effective cancer research显示文摘Cancer is a major stress for public well-being and is the most dreadful disease.The models used in the discovery of cancer treatment are continuously changing and extending toward advanced preclinical studies.Cancer models are either naturally existing or artificially prepared experimental systems that show similar features with human tumors though the heterogeneous nature of the tumor is very familiar.The choice of the most fitting model to best reflect the given tumor system is one of the real difficulties for cancer examination.Therefore,vast studies have been conducted on the cancer models for developing a better understanding of cancer invasion,progression,and early detection.These models give an insight into cancer etiology,molecular basis,host tumor interaction,the role of microenvironment,and tumor heterogeneity in tumor metastasis.These models are also used to predict novel can-cer markers,targeted therapies,and are extremely helpful in drug development.In this review,the potential of cancer models to be used as a platform for drug screening and therapeutic discoveries are highlighted.Although none of the cancer models is regarded as ideal because each is associated with essential caveats that restraint its application yet by bridging the gap between preliminary cancer research and transla-tional medicine.However,they promise a brighter future for cancer treatment. | Humna Sajjad Saiqa Imtiaz Tayyaba Noor Yusra Hasan Siddiqui Anila Sajjad Muhammad Zia | 2021 | Animal Models and Experimental Medicine2021，4，2： | 5 |
| 2 | Synergistic antibacterial effect of honey and Herba Ocimi Basilici against some bacterial pathogens显示文摘OBJECTIVE: To evaluate the antibacterial activity of the combination of different honey brands and methanolic fraction of Herba Ocimi Basilici using agar well diffusion assay. METHODS: The antibacterial activity was determined against thirteen pathogenic bacterial clinical isolates including six gram negative(Klebsiella pneumonia, Pseudomonas aeroginosa, Escherichia coli, Salmonella typhi, Salmonella typhimirium, Xanthomonas campestris) and six gram positive strains(Enterococcus faecalis faecalis, Bacillus subtilis, Staphylococcus aureus, Clostridium perfringens type C, Clostridium perfringens type D, Clostridium chauvoei). Agar well diffusion method was used while zones of inhibition were measured with vernier scale. RESULTS: At higher concentration, all the honey brands showed good to significant activity. The highest activity was observed for Hamdard brand honey(27.60±0.40) against Enterococcus faecalis. CONCLUSION: These results revealed that combinations of plant extracts of Herba Ocimi Basilici with honey can be used for the development of potent and novel antibacterial agents. | Ali Talha Khalil Imran Khan Kafeel Ahmad Yusra Ali Khan Momin Khan Muhammad Jaseem Khan | 2013 | Journal of Traditional Chinese Medicine2013，33，6： | 4 |
| 3 | Green composites from sustainable cellulose nanofibrils: A review显示文摘 | H.P.S. Abdul Khalil A.H. Bhat A.F. Ireana Yusra | 2011 | Carbohydrate Polymers2011，，2： | 2 |
| 4 | Antibacterial activity of honey in north-west Pakistan against select human pathogens显示文摘OBJECTIVE:To investigate the antimicrobial activity of commercially available honey and raw honey samples in Khyber Pakhtunkhwa,Pakistan,against pathogenic bacterial strains.METHODS:Well diffusion assays were performed to screen pure and diluted honey samples for antibacterial activity against six Gram-negative and six Gram-positive bacterial strains.Zones of inhibition were measured and compared with 10 mg Gentamycin.RESULTS:When honey samples were diluted to20%-70%,the honey samples showed no activity to mild antibacterial activity.The highest antibacterial activity was recorded when 90%and pure undiluted honey samples were tested and compared with a control Gentamycin disc(10 mg).CONCLUSION:Commercially processed honey and raw honey samples from north-west of Pakistan possess good antimicrobial potential. | Ali Talha Khalil Imran Khan Yusra Ali Khan Zabta Khan Shinwari Kafeel Ahmad Jangrez Khan | 2014 | Journal of Traditional Chinese Medicine2014，34，1： | 2 |
| 5 | Cell wall uhrastructure anatomy lignin distribution and chemical composition of Malaysian cultivat- ed kenaf fiber 显示文摘 | Khalil H Yusra A Bhat A | 2010 | Industrial Crops and Products2010，31，1： | 1 |
| 6 | Green composites from sustainable cellulose nanofibrils: A review 显示文摘 | ABDUL KHALIL H P S BHAT A H IREANA YUSRA A F | 2012 | Carbohydr Polym2012，87，2： | 1 |
| 7 | Green composites from sustainable cellulose nanofibrils: A review 显示文摘 | Abdul Khalil HPS Bhat A H Ireana Yusra AF | 2012 | Carbohydrate Polymers2012，87，2： | 1 |
| 8 | Green composites from sustainable cellulose nanofibrils:a review显示文摘 | Abdul Khalil H Bhat A H Ireana Yusra A F | | 0，，02： | 1 |
| 9 | Is the Irish bedside best显示文摘 | Callaly EL Yusra M Sreenan S | 2010 | Ir J Med Sci2010，179，： | 1 |
| 10 | 直接甲醇燃料电池用含纳米铜聚氯乙烯电化学氧化膜的制备与表征显示文摘采用化学还原法制备纳米铜颗粒,然后将其嵌入聚氯乙烯(PVC)基体中得到PVC/Cu膜,作为电极材料以提高甲醇燃料氧化的电流响应。用热重分析(TGA)表征PVC/Cu电极的热稳定性,用X射线衍射(XRD)检测电极中的铜纳米颗粒,用傅里叶变换红外光谱(FTIR)鉴定PVC与铜之间的相互反应,用扫描电镜(SEM)和能谱(EDAX)分析该电极的显微形貌,并用循环伏安法、线性扫描伏安法和计时电流法表征该电极的电催化活性。结果表明,随着铜含量从0.18 g(PVC/Cu-0.18 g)增加到0.24 g(PVC/Cu-0.24 g),电极的活性增加,且在铜含量为0.24 g时达到最大值。电极在0.5 mol/L CH3OH+1 mol/L Na OH溶液中达到最大催化电流。FTIR结果显示,电极中含有水分子、C—H基团、铜颗粒和铜的氧化物。SEM和EDAX结果表明,铜颗粒在聚氯乙烯基体中嵌入良好。 | Rohitash KUMAR Aftab Aslam Parwaz KHAN Anish KHAN Abdullah M ASIRI Yusra HAMID | 2020 | Transactions of Nonferrous Metals Society of China2020，30，8： | 1 |
| 11 | Green composites from sustainable cellulose nanofibrils:A review显示文摘 | KHALIL H P S A BHAT A H YUSRA A F I | 2012 | Carbohydrate Polymers2012，87，2： | 1 |
| 12 | Green composites from sustainable cellulose nanofibrils:a review显示文摘 | Abdul Khalil H P S Bhat A H Ireana Yusra A F | | Carbohydrate Polymers0，87，： | 1 |
| 13 | Green com- posites from sustainable cellulose nanofibrils: A review 显示文摘 | KHALI H P S A BHAT A H YUSRA A F I | 2012 | Carbohydr Polym2012，87，： | 1 |
| 14 | 显示文摘 | Khalil H P S A Bhat A H Yusra A F I | 2012 | Carbohydrate Pol- ymers2012，87，2： | 1 |
| 15 | Green com- posites from sustainable cellulose nanofibils: A review 显示文摘 | Abdul Khalil H P S Bhat A H Ireana Yusra A F | 2012 | Carbohydr Polym2012，87，2： | 1 |
| 16 | What is the Biology and Optimal Treatment for Papillary Microcarcinoma of the Thyroid?显示文摘 | Yusra Cheema Sarah Olson Diane Elson Herbert Chen | 2006 | Journal of Surgical Research2006，，2： | 1 |
| 17 | Kinetic and Thermodynamic Modeling for the Removal of Direct Red-31 and Direct Orange-26 Dyes from Aqueous Solutions by Rice Husk 显示文摘 | Yusra S Haq N B | 2011 | Desalination2011，272，123： | 1 |
| 18 | Comparison of image quality assessment: PSNR, HVS, SSIM, UIQI显示文摘 | Yusra A Y A N Der C S | 2012 | International Journal of Scientific and Engineering Research2012，3，1： | 1 |
| 19 | Risk profile and outcomes of aortic valve replacement in octogenarians显示文摘AIM: To investigate the patient characteristics, relationship between the Logistic EuroSCORE (LES) and the observed outcomes in octogenarians who underwent surgical aortic valve replacement (AVR). METHODS: Two hundred and seventy three octogenarians underwent AVR between 1996 and 2008 at Bristol Royal Inf irmary. Demographics, acute outcomes,length of hospital stay and mortality were obtained. The LES was calculated to characterize the predicted operative risk. Two groups were def ined: LES ≥ 15 (n = 80) and LES < 15 (n = 193). RESULTS: In patients with LES ≥ 15, 30 d mortality was 14% (95% CI: 7%-23%) compared with 4% (95% CI: 2%-8%) in the LES < 15 group (P < 0.007). Despite the increase in number of operations from 1996 to 2008, the average LES did not change. Only 5% of patients had prior bypass surgery. The LES identifi ed a low risk quartile of patients with a very low mortality (4%, n = 8, P < 0.007) at 30 d. The overall surgical results for octogenarians were excellent. The low risk group had an excellent outcome and the high risk group had a poor outcome after surgical AVR. CONCLUSION: It may be better treated with transcatheter aortic valve implantation. | Sujatha Kesavan Aamer Iqbal Yusra Khan Jonathan Hutter Katie Pike Chris Rogers Mark Turner Mandie Townsend Andreas Baumbach | 2011 | World Journal of Cardiology2011，3，11： | 1 |
| 20 | Green composites from sustainable cellulose nanofibrils : a review 显示文摘 | Abdul Khalil HPS Bhat AH Ireana Yusra AF | 2012 | Carbohydrate Polymers2012，87，： | 1 |
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