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| 1 | Trends of foodborne diseases in China: lessons from laboratory- based surveillance since 2011显示文摘Foodborne 疾病是世界范围的最重要的公共健康问题之一。中国在食物链的所有方面面对各种各样、崭新的挑战。从从 2013 ~ 2016 的基于实验室的 foodborne 疾病监视系统的数据,以及不同区域和年龄,能在与多样的特征检测的病原体的模式与差别一起被发现。Vibrio parahaemolyticus 是在中国的传染腹泻的领先的原因,特别在在沿海的区域的成年人之中。沙门氏菌是为实质的社会经济的负担负责的严肃、广泛地分布式的病原体。Shigella 主要在 5 年下面在孩子之中与开发更少的区域在西北中国和内陆省(河南省) 被识别。从从 2011 ~ 2016 报导系统的 foodborne 疾病爆发的数据证明有毒的动物和为大多数死亡负责的植物因素在在西南区域的遥远的区域是有毒的蘑菇(54.7%) 。引起了报导的大多数案例(42.3%) 的生物危险被归因于 V。parahaemolyticus, foodborne 爆发的领先的原因。在这评论,我们在中国总结最近的监视途径到 foodborne 疾病并且在发达国家把结果与那些作比较。 | Jikai Liu Li Bai Weiwei Li Haihong Han Ping Fu Xiaochen Ma Zhenwang Bi Xiaorong Yang Xiuli Zhang Shiqi Zhen Xiaoling Deng Xiumei Liu Yunchang Guo | 2018 | Frontiers of Medicine2018，12，1： | 55 |
| 2 | Mushroom Poisoning Outbreaks—China,2010–2020显示文摘ABSTRACT Introduction:Mushroom poisoning was the leading cause of foodborne disease outbreaks and outbreak-associated deaths in China.Mushroom poisoning outbreak surveillance can provide insight into the epidemiological characteristics of mushroom poisonings and guide policymaking and health education to reduce illnesses and deaths.Methods:Foodborne Disease Outbreak Surveillance System was upgraded in 2011 to collect foodborne disease outbreaks in China.Mushroom poisoning outbreaks during 2010–2020 were selected to analyze geographical distribution,seasonal distribution,and setting of food preparation.Results:A total of 10,036 outbreaks,which resulted in 38,676 illnesses and 788 deaths,were reported in this period.Mushroom poisonings occurred all over the country,but with highest incidence in the southwest and central China. | Weiwei Li Sara M.Pires Zhitao Liu Jinjun Liang Yafang Wang Wen Chen Chengwei Liu Jikai Liu Haihong Han Ping Fu Yunchang Guo | 2021 | China CDC weekly2021，3，24： | 18 |
| 3 | Characteristics of Settings and Etiologic Agents of Foodborne Disease Outbreaks—China,2020显示文摘Introduction:Foodborne diseases are a growing public health problem and have caused a large burden of disease in China.This study analyzed epidemiological characteristics of foodborne diseases in China in 2020 to provide a scientific basis for prevention and control measures.Methods:Data were collected from 30 of 31 provincial-level administrative divisions(PLADs)in the mainland of China,excluding Xizang(Tibet)Autonomous Region,via the National Foodborne Disease Outbreaks Surveillance System・The number and proportion of outbreaks,illnesses,hospitalizations,deaths by setting,pathogen-food category pairs and etiology were calculated.Results:In 2020,7,073 foodborne disease outbreaks were reported,resulting in 37,454 illnesses and 143 deaths.Among the identified pathogens,microbial pathogens were the most common confirmed etiology,accounting for 41.7%of illnesses.Poisonous mushrooms caused the largest proportion of outbreaks(58.0%)and deaths(57.6%).For venues where foodborne disease outbreaks occur,household had the highest number of outbreaks(4,140)and deaths(128),and catering service locations caused the largest proportion of illnesses(59.9%).Outbreaks occurring between June and September accounted for 62.8%of total outbreaks.Conclusions:Foodborne disease outbreaks mainly occurred in households・Microbial pathogens remained the top cause of outbreak-associated illnesses.Poisonous mushrooms were ranked the top cause of deaths in private homes in China.The supervision and management of food safety and health education should be strengthened to reduce the burden of foodborne diseases・Publicity should be increased to reduce the incidence of mushroom poisonings in families,and supervision and management of food should be strengthened to reduce microbial contamination. | Hongqiu Li Weiwei Li Yue Dai Yuyan Jiang Junhua Liang Santao Wang Maoqiang Zhuang Zheng Huang Lizi Xu Bo Xue Jikai Liu Haihong Han Sara M.Pires Ping Fu Yunchang Guo | 2021 | China CDC weekly2021，3，42： | 14 |
| 4 | Communication simulation of on-board diagnosis network in high-speed Maglev trains显示文摘The on-board diagnosis network is the nervous system of high-speed Maglev trains,connecting all controller,sensors,and corresponding devices to realize the information acquisition and control.In order to study the on-board di-agnosis network's security and reliability,a simulation model for the on-board diagnosis network of high-speed Mag-lev trains with the optimal network engineering tool(OPNET) was built to analyze the network's performance,such as response error and bit error rate on the network load,throughput,and node-state response.The simulation model was verified with an actual on-board diagnosis network structure.The results show that the model results obtained are in good agreement with actual system performance and can be used to achieve actual communication network optimiza-tion and control algorithms. | Zhigang LIU Yunchang HOU Weijie FU | 2011 | Journal of Modern Transportation2011，19，4： | 2 |
| 5 | Prevalence of Antimicrobial Resistant of Vibrio parahaemolyticus Isolated from Diarrheal Patients——Six PLADs,China,2016−2020显示文摘Summary What is already known on this topic?Vibrio parahaemolyticus(V.parahaemolyticus)is frequently resistant to common antimicrobials such as ampicillin and generally highly susceptible to most clinically used antimicrobials.What is added by this report?V.parahaemolyticus were highly resistant to cefazolin and ampicillin:94.4% and 37.0%,respectively. | Haihong Han Sara MPires Johanne Ellis-Iversen Zhen Tang Xiaoai Zhang Jikai Liu Weiwei Li Qingpo Cui Jing Zou Ping Fu Yunchang Guo | 2021 | China CDC weekly2021，3，29： | 2 |
| 6 | Diffraction transfer function and its calculation of classic diffraction formula显示文摘 | Junchang Li Zujie Peng Yunchang Fu | 2007 | Optics Communications2007，，2： | 1 |
| 7 | A theoretical model for laser and powder particles interaction during laser cladding显示文摘 | FU YUNCHANG LOREDO A MARTIN B | 2002 | Journal of Materials Processing Technology2002，128，13： | 1 |
| 8 | Diffraction transfer function and its calculation of classic diffraction formula显示文摘 | Li Junchang Peng Zujie Fu Yunchang | 2007 | OpticsCommunications2007，280，2： | 1 |
| 9 | Interplanting Patterns of Cash Crops under Forest显示文摘At the same time of tending forests,it is necessary to explore the under-forest economic development mode,bring into play production function of economic plants,establish cultivation mode of edible fungus,wild vegetables and medicinal plants under forest,to obtain certain economic benefit in short period. This paper made a preliminary study on significance and existing problems of the under-forest economy,and came up with several interplanting patterns,in the hope of providing a comprehensive operation and cultivation approach for developing the under-forest economy. | Renjie DU Yuejun QU Hu JIN Haibo JIANG Yunchang DU Dongyue ZHOU Jing FU Ping SHI | 2014 | Asian Agricultural Research2014，6，11： | 1 |
| 10 | A theoretical model for laser and powder particles interaction during laser cladding显示文摘 | Fu Yunchang Loredo A Martin B | 2002 | Journal of Materials Processing and Technology2002，128，： | 1 |
| 11 | ApoAⅠ/ABCA1通过STAT3/TTP途径调节炎症因子mRNA降解显示文摘目的观察ApoAⅠ对脂多糖(LPS)诱导的THP-1巨噬细胞源性泡沫细胞炎症因子表达的影响,并从ABCA1介导激活的STAT3/TTP信号途径入手探讨其分子机制。方法采用ELISA检测炎症因子表达;构建含肿瘤坏死因子α(TNF-α)启动子的CAT报告基因,转染THP-1细胞,采用ELISA检测TNF-α启动子活性;定量PCR检测TNF-α等炎症因子mRNA表达;免疫印迹技术检测pSTAT3、TTP和HuR等蛋白表达;RNA-EMSA检测TTP与RNA复合物;构建TTP、STAT3 siRNA,转染细胞。结果用10μg/L LPS和/或10 mg/L ApoAⅠ处理THP-1源性泡沫细胞4 h,结果显示ApoAⅠ明显抑制LPS诱导的TNF-α、IL-1β和IL-6的表达;CAT报告基因显示,ApoAⅠ并不明显影响LPS诱导的TNF-α启动子活性;LPS处理细胞3 h,加入放线菌素D(Act D)终止转录,检测TNF-αmRNA表达量(0、30、60及120 min),结果显示ApoAⅠ明显增加LPS作用下TNF-α的mRNA降解;ApoAⅠ明显促进LPS作用下TTP的表达,而对HuR的表达没有明显影响,TTP siRNA处理后明显抑制ApoAⅠ促进TNF-αmRNA降解的作用;RNA-EMSA结果显示,ApoAⅠ明显促进胞内蛋白与ARE探针形成复合物,加入TTP抗体形成su-pershift;ApoAⅠ处理THP-1细胞后迅速(15 min)磷酸化STAT3,核内STAT3表达增加,STAT1和STAT6不受影响;STAT3 siR-NA处理后明显抑制TTP的表达及TNF-αmRNA的降解;采用siRNA下调ABCA1的表达,明显抑制ApoAⅠ作用下TTP的表达及TNF-αmRNA的降解。结论 ApoAⅠ通过转录后调控方式抑制LPS诱导的炎症因子表达;ApoAⅠ促进TTP表达,并通过与炎症因子3′UTR ARE序列结合促进其mRNA降解;ApoAⅠ通过激活STAT3促进TTP表达,该效应直接受ABCA1介导。 | 尹凯 莫中成 赵国军 姜津 崔立宝 Yunchang Fu 唐朝克 | 2011 | 中国动脉硬化杂志2011，19，3： | 1 |
| 12 | Genetic relationship of rapeseed yield-related traits revealed by elite lines under multiple environments显示文摘 | Hui WANG Qiong HU Jun WANG Yunchang LI Li FU Jia LIU Zhongfen WEI Wenxiang WANG Desheng MEI | 2016 | Oil Crop Science2016，1，2： | 0 |
| 13 | Microstructure and texture in an extruded Mg-Al-Ca-Mn flat-oval tube显示文摘In the present study,mechanical property,microstructure and texture of an extruded Mg–1.0Al–1.5Ca–1.0Mn(wt.%)flat-oval tube in both the flat and the oval regions were systematically studied.Our results show that there exists a great difference in microstructure and texture between the flat and the oval regions.Both the flat and the oval regions have fine DRXed grains of 3–4μm,while more row stacked grains are observed in the flat region.A large number of fine particles with a size of about 0.5μm are dispersed in both the grain boundary and grain interior.The particles exhibit a uniform distribution in the oval region,while they tend to aggregate into bands along the extrusion direction(ED)in the flat region.The texture in the oval region is similar to that in extruded Mg rods with a preferred distribution of prismatic planes and random distribution of(0002)poles around the ED,while that in the flat region is close to that in extruded sheets containing two texture components,<0002>//normal direction(ND)and<0002>//transverse direction(TD).A high fraction of<0002>//TD component,about 52–62%,is observed in the flat region.The flat region has a tensile yield strength of 254 MPa,an ultimate tensile strength of 290 MPa and an elongation to failure of 4.3%. | Feilong Guo Bo Feng Shiwei Fu Yunchang Xin Shiwei Xu Qing Liu | 2017 | Journal of Magnesium and Alloys2017，5，1： | 0 |
| 14 | Deformation mechanisms and differential work hardening behavior of AZ31 magnesium alloy during biaxial deformation显示文摘Magnesium alloys are frequently subjected to biaxial stress during manufacturing process,however,the work hardening behavior under such circumstance are not well understood.In this study,the deformation mechanisms and differential work hardening behavior of rolled AZ31 magnesium alloy sheets under biaxial loading are investigated.The change of plastic work contours with increasing plastic strain indicates the differential work hardening behavior of AZ31 magnesium alloy under biaxial stress state,resulting in higher macroscopic work hardening rates of biaxial loading than uniaxial loading,with the elastic-plastic transition part of work hardening extended and stage Ⅲ hardly emerged.Electron backscatter diffraction and Schmid factor analysis confirm the low activation of non-basalslip during biaxial loading tests.While the thickness strain is primarily accommodated by pyramidalslip at the initial stage of biaxial deformation,{10–11}contraction twinning is activated at larger plastic strain.The low activation of non-basalslip also retards the dynamic recovery and cross-slip of basal and prismaticslips,leading to the differential work hardening behavior of AZ31 magnesium alloy under biaxial stress state. | Yuanjie Fu Yao Cheng Yun Cui Yunchang Xin Shouwen Shi Gang Chen | 2022 | Journal of Magnesium and Alloys2022，10，2： | 0 |
| 15 | On the modeling of deformation mechanisms in a Mg-3Al-1Zn alloy under biaxial tension显示文摘Although the{10-12}twinning behavior of Mg alloys under uniaxial tension and compression has been extensively investigated,the simulations of{10-12}twinning behavior under biaxial tension have rarely been reported.In this work,the EVPSC-TDT model is first employed to systematically investigate the deformation behavior of a Mg alloy AZ31 plate under biaxial tension in the RD-TD and ND-TD planes.The RD,TD and ND refer to the rolling direction,transverse direction,and normal direction of the hot rolled plate.The measured stress-strain curves and texture evolutions are well predicted and the con-tours of plastic work under biaxial tension are also constructed for comparison with experiments.The plastic response has been interpreted in terms of relative activities of various deformation modes.For bi-axial tension in the RD-TD plane,basal and pyramidal slips mainly contribute to the plastic deformation for stress ratios ofσRD:σTD=1:2 to 2:1.Prismatic slip becomes more active forσRD:σTD=1:4 and 4:1.Compression twinning could be activated and so cause texture reorientation at large strains,especially forσRD:σTD=1:1.The six-fold feature of{10-10}pole figure could still be observed forσRD:σTD=1:4 and 4:1 at large strain.For biaxial tension in the ND-TD plane,tensile twinning plays an important role forσND:σTD≥1:2,while prismatic slip contributes to plastic deformation for the other cases.With the in-crease of stress ratio fromσND:σTD≥1:1 to 1:0,the predicted twin volume fractions(VFs)at a specific strain along the ND,εND,almost linearly decrease,however,it is seen that the experimental ones at given strains along the ND do not follow such a trend with the measured twin VFs within the range of stress ratios,2:1≤σND:σTD≤6:1,clearly being overestimated,and the difference between experiments and simulations becomes most obvious at the relatively small strain ofεND=0.015.The possible reasons for the observed difference are discussed. | Hua Qiao Yao Cheng Yuanjie Fu Yunchang Xin Gang Chen Peidong Wu | 2023 | Journal of Materials Science & Technology2023，，14： | 0 |
| 16 | Epidemiological Evaluation of Bacillus cereus-Induced Foodborne Outbreaks — China, 2010–2020显示文摘Introduction:Bacillus cereus(B.cereus)is a common gram-positive bacterium that contaminates starch-rich food and can cause outbreaks of foodborne diseases.This study describes characteristics of outbreaks caused by B.cereus in China during 2010–2020 and explore the possible reasons for changes in the number of outbreaks over time.Results of this analysis can efficiently help guide and allocate public resources to prevent B.cereus caused foodborne diseases.Methods:Descriptive statistical methods were used to analysis the data on B.cereus outbreaks in China during this period.The data were identified,reported at all levels in China through National Foodborne Disease Outbreak Surveillance System.Results:From 2010 to 2020,a total of 419 foodborne outbreaks prompted by B.cereus were reported in China,leading to 7,892 cases,2,786 hospital admissions,and 5 fatalities.The bulk of the outbreaks were recorded in the summer,primarily between May and September.The most recurrent food vehicle was linked with rice or flour-based products,notably those made with rice or fried rice.School canteens bore the brunt of the B.cereus outbreaks.In multifactor outbreaks,food contamination was identified as the most common culprit;while in instances where only one factor contributed,improper storage was most frequently implicated.Conclusion:The prevalence of B.cereus outbreaks remained relatively consistent throughout the studied period.Understanding the types of foods,causative factors,and contributing elements leading to B.cereus outbreaks can help inform prevention strategies for foodborne illnesses.The majority of outbreaks were associated with rice-or flour-based foods in school canteens,suggesting contamination and improper storage during food preparation.Consequently,it is essential to prioritize continuous education for canteen staff on food safety,efficacious management,and proper practices.The implementation of comprehensive guidelines,encompassing multiple critical aspects,can potentially reduce the occurrence of B.cereus outbreaks. | Shenggang Duan Yue Yu Yunchang Guo Donglei Lu Ning Li Zhitao Liu Jinjun Liang Yuyan Jiang Santao Wang Ping Fu Jikai Liu Hong Liu | 2023 | China CDC weekly2023，5，33： | 0 |
| 17 | Epidemiological Features of Foodborne Disease Outbreaks in Catering Service Facilities—China,2010–2020显示文摘Introduction:In terms of food preparation settings,catering service facilities have been identified as locations with the highest incidence of foodborne disease outbreaks in China.Since 2010,the China National Center for Food Safety Risk Assessment has established the Foodborne Disease Outbreak Surveillance System(FDOSS)to monitor foodborne disease outbreaks.Consequently,data from the FDOSS has provided a more accurate depiction of the epidemic characteristics of outbreaks within these facilities.Methods:From 2010 to 2020,the FDOSS gathered data related to the prevalence of outbreaks,cases,hospitalizations,and deaths linked to foodborne disease outbreaks in catering service facilities.This study examined the temporal and geographical distribution,pathogenic factors,and contributing variables of these outbreaks over the course of the decade.Results:From 2010 to 2020,China’s catering service facilities reported 18,331 outbreaks,which resulted in 206,718 illnesses,68,561 hospitalizations,and 201 deaths.The second and third quarters of the year accounted for 76.12%of the outbreaks and 72.93%of the cases.The primary pathogenic factors were pathogenic organisms,which caused 4,883(26.64%)outbreaks,94,047(45.50%)cases,32,170(46.92%)hospitalizations,and 21(10.45%)deaths.There were 5,607(30.59%)outbreaks in restaurants,2,876(15.69%)outbreaks from street vendors,and 2,560(13.97%)outbreaks in employee canteens in China.Conclusions:The implementation of relevant control methods,including health education and promotion,is critical for addressing foodborne diseases in catering service facilities.Regular food safety training sessions for restaurant personnel and managers are essential to ensuring the effective management of these health risks. | Donglei Lu Jikai Liu Hong Liu Yunchang Guo Yue Dai Junhua Liang Lili Chen Lizi Xu Ping Fu Ning Li | 2023 | China CDC weekly2023，5，22： | 0 |
| 18 | Deformation mechanism of commercially pure titanium under biaxial loading at ambient and elevated temperatures显示文摘Commercially pure(CP)titanium is thermally processed and subjected to biaxial stress.However,the evolution of the microstructural deformation mechanisms under such circumstances is not adequately understood.In this study,the mechanical responses and microstructural deformation mechanisms of TA2 CP titanium sheets under equi-biaxial loading at room temperature(RT),300℃,and 400℃were studied.The activated slip and twinning systems were investigated by transmission electron microscopy(TEM)after polished cruciform specimens were biaxially tensile-tested at RT and elevated temperatures.The results show that{11¯22}contraction twinning and{10¯12}extension twinning are the main deforma-tion mechanisms of RT biaxial deformation,while dislocation glide is predominant in biaxial deformation at 300℃and 400℃.This difference yields varied work-hardening behaviors at RT and elevated tem-peratures.In biaxial deformation at 400℃,the main slip trace type is multiple slip.The interaction of different slip systems in multiple slip created shear deformation concentration areas and further induced cross-slip.However,in biaxial deformation at 300℃,the amounts of simplex and multiple slip were significantly reduced compared to those at 400℃because the lower temperature increased the critical resolved shear stress and insufficient activated slip systems were available for grain deformation.There-fore,several stress-concentration areas were generated with the activation of cross-slip. | Yuanjie Fu Yao Cheng Yun Cui Yunchang Xin Yuyao Zeng Xiao Liu Gang Chen | 2022 | Journal of Materials Science & Technology2022，，31： | 0 |
| 19 | Epidemiological Analysis of Foodborne Botulism Outbreaks-China,2004-2020显示文摘Introduction:Foodborne botulism is a rare,potentially fatal illness resulting from the ingestion of foods contaminated with preformed botulinum neurotoxin types A,B,E,or F,produced by Clostridium botulinum.The descriptive epidemiology of foodborne botulism outbreaks in China during 2004−2020 was performed to inform public health response strategies.Methods:Data from 22 of 31 provincial-level administrative divisions(PLADs)of the National Foodborne Disease Outbreaks Surveillance System during 2004−2020 and Embase,China National Knowledge Infrastructure(CNKI),Wanfang Data,and Chinese Science and Technique Journals(CQVIP)from January 2004 to December 2020 to identify indexed publications in the Chinese literature using the following search terms“botulism,”or“botulinum toxin,”or“Clostridium botulinum.”The number and proportion of outbreaks,illnesses,and deaths by PLAD,food types,and contributing factors were calculated.Results:During 2004−2020,a total of 80 foodborne botulism outbreaks occurred in China,involving 386 illnesses and 55 deaths;most outbreaks were reported between June and August,with a sharp peak in January;22 out of 31 PLADs reported foodborne botulism outbreaks,Xinjiang reported the largest number of outbreaks(20),followed by Qinghai(13);the most commonly implicated foods were homeprepared traditional processed stinky tofu and dried beef,accounting for 51.25%events.Improper processing and improper storage in contributing factors accounted for 77.50%outbreaks.Initial misdiagnosis occurred in 27.50%of cases.Conclusions:Outbreaks of foodborne botulism had a high case-fatality rate.Targeted food safety and popularization education to farmers and herdsmen in Xinjiang and Qinghai related to botulism prevention should be carried out,and timely outbreak investigation and hospital surge capacity should be improved. | Hongqiu Li Yunchang Guo Tian Tian Wanhua Guo Changqing Liu Xiaocheng Liang Jikai Liu Weiwei Li Ping Fu | 2022 | China CDC weekly2022，4，35： | 0 |
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