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| 1 | Update on cerebral small vessel disease: a dynamic whole-brain disease显示文摘Cerebral small vessel disease(CSVD)is a very common neurological disease in older people.It causes stroke and dementia,mood disturbance and gait problems.Since it is difficult to visualise CSVD pathologies in vivo,the diagnosis of CSVD has relied on imaging findings including white matter hyperintensities,lacunar ischaemic stroke,lacunes,microbleeds,visible perivascular spaces and many haemorrhagic strokes.However,variations in the use of definition and terms of these features have probably caused confusion and difficulties in interpreting results of previous studies.A standardised use of terms should be encouraged in CSVD research.These CSVD features have long been regarded as different lesions,but emerging evidence has indicated that they might share some common intrinsic microvascular pathologies and therefore,owing to its diffuse nature,CSVD should be regarded as a‘whole-brain disease’.Single antiplatelet(for acute lacunar ischaemic stroke)and management of traditional risk factors still remain the most important therapeutic and preventive approach,due to limited understanding of pathophysiology in CSVD.Increasing evidence suggests that new studies should consider drugs that target endothelium and blood–brain barrier to prevent and treat CSVD.Epidemiology of CSVD might differ in Asian compared with Western populations(where most results and guidelines about CSVD and stroke originate),but more community-based data and clear stratification of stroke types are required to address this. | Yulu Shi Joanna M Wardlaw | 2016 | Stroke & Vascular Neurology2016，1，3： | 74 |
| 2 | A Practical Approach to Constructing a Knowledge Graph for Cybersecurity显示文摘 | Yan Jia Yulu Qi Huaijun Shang Rong Jiang Aiping Li | 2018 | Engineering2018，4，1： | 29 |
| 3 | 柚喀木虱的形态、生物学特性及发生规律研究显示文摘柚喀木虱Cacopsylla citrisuga Yang&Li是云南省德宏州柠檬产区为害柠檬嫩梢、嫩叶的一种害虫,在该产区的柚喀木虱若虫体内检测到黄龙病亚洲种病原菌,对柚喀木虱的形态、生物学特性及发生规律进行了研究.结果表明:柚喀木虱主要发生在德宏州海拔1 000~1 500 m的柠檬产区,其寄主植物仅发现芸香科柑橘属Citrus和枳壳Poncirus trifoliate,海拔越高,发生时间越长,受害越重;以若虫为害最为严重,受害叶片不能正常生长及展开,出现对折症状,严重时卷曲成菊花状;其种群数量的变化及为害高峰期与柠檬抽发、海拔高度及气温密切相关. | 郭俊 岑伊静 王自然 段惠芬 YULU XIA 高俊燕 | 2012 | 华南农业大学学报2012，33，4： | 15 |
| 4 | 适配太阳能诱虫器诱杀柑橘木虱LED光源的筛选显示文摘柑橘木虱(Diaphorina citri)是柑橘黄龙病的传播媒介。为达到治虫防病的目的,在室内利用昆虫行为反应器开展适配太阳能诱虫器的LED光源筛选,结果表明:柑橘木虱成虫对光照强度分别为1 800lx和4 310lx的蓝光和绿光(波长分别为460nm和531nm)在光照时长为17h时的趋光性最佳,相同波长条件下,其趋光性与光照强度和光照时长成正相关。该研究结果为进一步探索适宜田间柑橘木虱测报和高效诱杀的LED光源提供理论依据。 | 林雄杰 范国成 胡菡青 阮传清 蔡子坚 Xia Yulu 杜云贵 刘波 | 2013 | 植物保护2013，39，4： | 13 |
| 5 | The crosstalk between autophagy and ferroptosis:what can we learn to target drug resistance in cancer?显示文摘Autophagy is a conserved intracellular degradation system that plays a dual role in cell death;thus,therapies targeting autophagy in cancer are somewhat controversial.Ferroptosis is a new form of regulated cell death featured with the iron-dependent accumulation of lethal lipid ROS.This pathway is morphologically,biochemically and genetically distinct from other forms of cell death.Accumulating studies have revealed crosstalk between autophagy and ferroptosis at the molecular level.In this review,we summarize the mechanisms of ferroptosis and autophagy,and more importantly,their roles in the drug resistance of cancer.Numerous connections between ferroptosis and autophagy have been revealed,and a strong causal relationship exists wherein one process controls the other and can be utilized as potential therapeutic targets for cancer.The elucidation of when and how to modulate their crosstalk using therapeutic strategies depends on an understanding of the fine-tuned switch between ferroptosis and autophagy,and approaches designed to manipulate the intensity of autophagy might be the key. | Yulu Zhou Yong Shen Cong Chen Xinbing Sui Jingjing Yang Linbo Wang Jichun Zhou | 2019 | Cancer Biology & Medicine2019，16，4： | 9 |
| 6 | Acute and chronic toxic effects of Pb^(2+)on polychaete Perinereis aibuhitensis:Morphological changes and responses of the antioxidant system显示文摘Perinereis aibuhitensis was used to assess adverse biological effects caused by acute and chronic Pb2+exposure in artificial seawater under controlled laboratory conditions. In 96-hr acute toxicity experiments,the morphological changes showed a positive time/dose-dependent tendency,and the 96-hr LC50 value of Pb2+was 686.41 mg/L. The responses of enzymatic and non-enzymatic antioxidants in tissues including catalase(CAT),peroxidase(POD),superoxide dismutase(SOD),glutathione peroxidase(GSH-PX),malondialdehyde(MDA) and the content of total soluble protein(TSP),were investigated on days 1,4,7 and 10 after Pb2+exposure under chronic toxicity testing. Results showed that the activation of the antioxidant system in P. aibuhitensis depended on the Pb2+concentration and the duration of exposure time.Specifically,POD and SOD activities were induced on the first day of the exposure and decreased to the control level on day 10 after exposure. Therefore,these two indexes could be used to indicate oxidative stress associated with P. aibuhitensis exposure to Pb2+. | Yulu Tian Hongjun Liu Qixiang Wang Jian Zhou Xuexi Tang | 2014 | Journal of Environmental Sciences2014，26，8： | 8 |
| 7 | Multi-omics analyses of 398 foxtail millet accessions reveal genomic regions associated with domestication,metabolite traits,and antiinflammatory effects显示文摘Foxtail millet(Setaria italica),which was domesticatedfromthewild speciesgreenfoxtail(Setaria viridis),isa richsource of phytonutrientsfor humans.To evaluate how breeding changed themetabolome offoxtail millet grains,we generated and analyzed the datasets encompassing the genomes,transcriptomes,metabolomes,and anti-inflammatory indices from 398 foxtail millet accessions.We identified hundreds of common variants that influence numerous secondary metabolites.We observed tremendous differences in natural variations of the metabolites and their underlying genetic architectures between distinct sub-groups of foxtail millet.Furthermore,we found that the selection of the gene alleles associated with yellow grains led to altered profiles of metabolites such as carotenoids and endogenous phytohormones.Using CRiSPR-mediated genome editing wevalidated the function of PHYTOENE SYNTHASE1(PSY1)gene in affecting milletgrain colorand quality.Interestingly,our in vitro cell inflammation assays showed that 83 metabolites in millet grains have anti-inflammatory effects.Taken together,ourmulti-omics study illustrates how the breeding history of foxtail millet has shaped its metabolite profile.The datasets we generated in this study also provide important resources for further understanding how millet grain quality is affected by different metabolites,laying the foundations for future millet genetic research and metabolome-assisted improvement. | Xukai Li Jianhua Gao Jingyi Song Kai Guo Siyu Hou Xingchun Wang Qiang He Yanyan Zhang Yakun Zhang Yulu Yang Jiaoyan Tang Hailang Wang Staffan Persson Mingquan Huang Lishuai Xu Linlin Zhong Dongqin Li Yongming Liu Hua Wu Xianmin Diao Peng Chen Xiaowen Wang Yuanhuai Han | 2022 | Molecular Plant2022，15，8： | 8 |
| 8 | 田间自然热罩治疗柑橘黄龙病的效果分析显示文摘【目的】为探讨柑橘黄龙病防控新途径,利用夏秋季强太阳光照,开展自然热罩处理对田间柑橘黄龙病树的治疗效果研究。【方法】2012年和2013年8—9月,分别选取40株PCR检测结果为阳性、5~8 a生的芦柑病树为试验对象。按每5株为1组,随机分为8组,其中4组为覆盖热罩处理组,其余4组为对照组。处理组病树用聚氯乙烯薄膜覆盖,地面以土块压实,并在病树正上方的覆盖薄膜上打10个直径约2 cm的小孔,覆盖时间7 h(10:00—17:00),间歇处理3次;对照组病树不做热罩处理。以温度数据记录仪,每5 min记录1次处理与对照温度数据。处理前、处理后30 d和90 d,分别选10株处理组及对照组病树进行症状评价,按病情分级计算其病情指数并进行显著性分析。同时,处理前、处理后30 d和90 d,分别采集症状明显的叶片提取DNA,以实时荧光定量PCR检测其病菌浓度。【结果】2 a处理结果表明,病树经3次间歇性自然热罩,90 d后症状明显减轻,抽生新梢,叶片正常成熟转绿,未出现新的黄化或斑驳等典型黄龙病症状,病情指数分别从67.00和68.33减为34.00和30.33,变化差异极显著;对照组病树病情持续加重,黄化症状更加明显,部分叶片出现木栓化,其病情指数分别从64.33和65.67增为89.00和87.00,变化差异极显著。荧光定量PCR检测结果显示,处理后90 d病菌浓度分别下降了85.36%和81.67%,其中27株降低了90%以上;对照组病菌浓度分别增加了22.86倍和25.50倍,最多的增加了95倍。【结论】通过3次间歇性自然热罩处理,90 d后田间柑橘黄龙病树症状明显减轻,黄龙病菌浓度也显著降低,平均下降达80%以上,最高下降了99.98%,其中有67.5%的病树病菌浓度降低了90%以上;而对照组病树除1株外,其余病菌浓度均不同程度增加,平均增加了20多倍。 | 范国成 林雄杰 王贤达 胡菡青 XIA Yulu | 2016 | 果树学报2016，33，9： | 8 |
| 9 | Changes in T lymphocyte subsets after severe traumatic brain injury显示文摘BACKGROUND: Besides local changes of cranial parenchymal cells, hemorrhage, etc., severe traumatic brain injuries also cause the changes of total body fluid and various functions, and the changes of lymphocytes and T lymphocyte subsets should be paid more attention to. OBJECTIVE: To reveal the changing laws of T lymphocyte subsets after severe traumatic brain injury, and compare with mild to moderate brain injury. DESIGN: A comparative observation. SETTINGS: Department of Neurosurgery, Longgang District Buji People's Hospital of Shenzhen City; Central Laboratory of Shenzhen Hospital of Prevention and Cure for Chronic Disease. PARTICIPANTS: All the subjects were selected from the Department of Neurosurgery, Longgang District Buji People's Hospital of Shenzhen City from August 2002 to August 2005. Thirty patients with severe brain injury, whose Glasgow coma score (GCS) was ≤ 8 points, were taken as the experimental group, including 21 males and 9 females, aging 16–62 years. Meanwhile, 30 patients with mild traumatic brain injury were taken as the control group (GCS ranged 14–15 points), including 18 males and 12 females, aging 15–58 years. All the subjects were in admission at 6 hours after injury, without disease of major organs before injury. Informed consents were obtained from all the patients or their relatives. METHODS: ① The T lymphocytes and the subsets in peripheral blood were detected with immunofluorescent tricolor flow cytometry at 1, 3, 7 and 14 days after injury in both groups. ② The conditions of pulmonary infections were observed at 4 days after injury. The differences of measurement data were compared with the t test. MAIN OUTCOME MEASURES: Changes of T lymphocytes subsets at 1–14 days after severe and mild or moderate traumatic injury. RESULTS: Finally, 28 and 25 patients with mild to moderate traumatic brain injury, whereas 25 and 21 patients with severe traumatic brain injury were analyzed at 7 and 14 days respectively, and the missed ones died due to the development of disease. ① Changes of T lymphocyte subsets: At 1 and 3 days after injury, CD3, CD4, CD8, CD4/CD8 began to decrease, whereas CD8 increased in the experimental group, which were very significantly different from those in the control group (t =2.77–3.26, P < 0.01), and began to recover at 7 days, which were significantly different from those in the control group (t = 2.06–2.24, P < 0.05), and generally recovered to the normal levels at 14 days (P > 0.05). ② Conditions of pulmonary infections: At 4 days after injury, the rate of pulmonary infection was significantly different between the experimental group and control group [73% (22/30), 0, χ2=37.29, P < 0.01]. CONCLUSION: Patients with severe traumatic brain injury suffer from damages of cellular immune function at early period (within 7 days), and they are easily to be accompanied by pulmonary infections. | Yulu Miao Mingxia Zhang Yulin Nie Wan Zhao Bin Huang Zhengming Jiang Shaoxiong Yu Zhibin Huang Hongjin Fu | 2007 | Neural Regeneration Research2007，2，2： | 7 |
| 10 | 基于柑橘木虱COⅠ基因的捕食性天敌捕食作用评估显示文摘捕食性天敌是害虫生物防治中的重要角色,如何精确评估捕食性天敌的捕食作用是生态学中尚待研究的问题之一。为探索柑橘园捕食性天敌对柑橘木虱Diaphorina citri的捕食作用,根据柑橘木虱细胞色素氧化酶I(COⅠ)的基因序列设计了PCR特异性引物,并应用DNA标记方法检测捕食性天敌对柑橘木虱的捕食作用。物种特异性检验结果发现:引物对A对柑橘木虱DNA扩增效果明显,对其他种类的害虫及其天敌不具有扩增作用。田间检测结果表明:在所检测的8类群20种捕食性天敌中,龟纹瓢虫Propylea japonica、斜纹猫蛛Oxyopes sertatus、丽草蛉Chrysopa formosa对柑橘木虱具有明显的捕食作用,其阳性反应检出率分别达到58.06%,57.89%,48.00%。室内龟纹瓢虫对柑橘木虱的消化检测表明:龟纹瓢虫成虫取食1头柑橘木虱4龄若虫或成虫时,检测阳性率均随消化时间的延长而下降,其消化半衰期分别为4.93 h和12.98 h。采用DNA标记技术探索捕食作用,为筛选柑橘木虱的优势天敌拓展了新的思路,也为进一步田间生物防治柑橘木虱奠定了基础。 | 孟翔 欧阳革成 Xia Yulu 郭明昉 | 2013 | 生态学报2013，33，23： | 6 |
| 11 | Autogenous inside-out versus standard vein and skeletal muscle-combined grafting for facial nerve repair显示文摘BACKGROUND:In the repair of nerve defects,collapse of the venous wall,as a result of vein grafting alone,could impede nerve regeneration.Therefore,vein lumens filled with muscle and nerve segments have been used to bridge nerve defects.OBJECTIVE:To compare the effects of autogenous,inside-out,vein-skeletal,muscle-combined grafting versus standard,vein-skeletal,muscle-combined grafting for the repair of facial nerve defects.DESIGN,TIME AND SETTING:A randomized,controlled,neuroanatomical,animal study was performed at the Animal Experimental Center and Laboratories of the Capital Medical University Xuanwu Hospital and the Peking Union Medical College Hospital from September 2007 to October 2008.MATERIALS:A total of 10 healthy,male,New Zealand rabbits,aged 6 months,were randomly assigned to inside-out,vein-skeletal,muscle-combined grafting and standard,vein-skeletal,muscle-combined grafting groups,with 5 rabbits in each group.METHODS:A 20-mm gap in the buccal branch of the right facial nerve was made in each animal,which was respectively repaired with inside-out,vein-skeletal,muscle-combined grafts or standard vein-skeletal muscle-combined grafts.MAIN OUTCOME MEASURES:At 6 months after implantation,evoked maximal compound muscle action potentials were recorded on bilateral facial nerves using electromyogram.Myelinated nerve fibers of the regenerating nerves were quantified using myelin sheath osmic acid staining.RESULTS:There was no significant difference between the groups in terms of ratios of bilateral amplitude and latency of compound muscle action potential(P>0.05).Moreover,morphology of regenerating nerves and quantity of myelinated nerve fibers were similar between the groups(P> 0.05).CONCLUTION:Compared with standard vein grafting,the inside-out vein grafting did not significantly improve nerve regeneration.Therefore,it is not necessary to utilize inside-out vein grafting for the repair of nerve defects,in particular with the combined use of autogenous vein and skeletal muscle grafts. | Yulu Li Zhiqiang Gao Zhenlin Wang Yonggang Liu Qiuhang Zhang | 2010 | Neural Regeneration Research2010，5，4： | 5 |
| 12 | Percutaneous absorption and brain distribution facilitation of borneol on tetramethylpyrazine in a microemulsion-based transdermal therapeutic system显示文摘In this study, we show that the percutaneous absorption and brain distribution of tetramethylpyrazine(TMP) is enhanced when combined with borneol(BN) in a microemulsionbased transdermal therapeutic system(ME-TTS). The formulation of the TMP and BN microemulsion(TEM-BN-ME) was optimized in skin permeation studies in vitro following a uniform experimental design. Male Sprague-Dawley rats were used for the in vivo pharmacokinetic and tissue distribution studies of TMP-BN-ME-TTS. In the pharmacokinetic study, the TMP-BN-ME-TTS treated rats had significantly higher( P < 0.05) C max and AUC of TMP than the TMP-ME-TTS treated rats, indicating that BN improves the rate and extent of TMP percutaneous absorption. In the tissue distribution study, the AUC of TMP in brain was significantly higher in the TMP-BN-ME-TTS group( P < 0.05), indicating that BN facilitates the distribution of TMP in brain. In summary, BN enhanced the percutaneous absorption and brain distribution of TMP in a microemulsion-based transdermal therapeutic system. | Xiaoge Hu Ning Cheng Jihui Zhao Xianghua Piao Yulu Yan Qibo Zhang Kuan Zhou Yongtai Zhang Nianping Feng | 2019 | Asian Journal of Pharmaceutical Sciences2019，14，3： | 4 |
| 13 | 湿度对田间自然热罩防治柑橘黄龙病的影响显示文摘比较加湿处理后热罩和自然条件下热罩对黄龙病的防治效果,结果表明自然条件处理后30d叶片平均病菌浓度下降了85%以上,而加湿条件下叶片平均病菌浓度仅下降3.7%,与自然条件处理间差异达到显著水平;自然条件热罩处理后90d叶片平均病菌浓度下降了97%以上,而加湿处理病树叶片平均病菌浓度下降了38%,与自然条件处理间的差异达到极显著水平。对照组叶片平均病菌浓度处理后30d和90d均有略微增加;加湿未热罩处理叶片平均病菌浓度在处理后30d和90d分别增加了4.5倍和8.7倍,但与对照组无显著差异。本研究结果表明加湿热罩处理病树显著减弱了其杀灭黄龙病菌效果,同时表明增加土壤湿度对黄龙病菌繁殖可能具有一定的促进作用。 | 林雄杰 范国成 胡菡青 王贤达 Yulu Xia 蔡子坚 刘波 | 2014 | 福建农业学报2014，29，5： | 4 |
| 14 | Internationalization of the RMB:An Evaluation Framework显示文摘As the Chinese economy continues to develop,China is becoming a more active player in the world economy,and the RMB is being more widely used in international markets.In this paper we use indicators representing the RMB’s functions of pricing,settlement and reserve to create an RMB Internationalization Index(RII)to evaluate the degree of the internationalization of the currency.We calculate the RII levels in 2010 and 2011,and find that the RII increased dramatically during these two years.However,when compared to the currencies of developed countries,the RMB is far from achieving complete internationalization.We propose a'three-step development'strategy for the RMB to be internationalized. | YULU CHEN BO HU | 2013 | Economic and Political Studies2013，1，1： | 4 |
| 15 | Biexciton Auger recombination in mono-dispersed, quantum-confined CsPbBr3 perovskite nanocrystals obeys universal volume-scaling显示文摘Auger recombination has been a long?standing obstacle to many prospective applications of colloidal quantum dots (QDs) ranging from lasing, light-emitting diodes to bio-labeling. As such, understanding the physical underpinnings and scaling laws for Auger recombination is essential to these applications. Previous studies of biexciton Auger recombination in various QDs established a universal scaling of biexciton lifetime (rxx) with QD volume (V):τxx =γV. However, recent measurements on perovskite nanocrystals (NCs), an emerging class of enablers for light harvest!ng and emitting applications, showed significant deviations from this universal scaling law, likely because the measured NCs are weakly-confined and also have relatively broad size-distributions. Here we study biexciton Auger recombination in mono-dispersed (size distributions within 1.7%—9.0%), quantunvconfined CsPbBr3 NCs (with confinement energy up to 410 meV) synthesized using a latest approach based on thermodynamic equilibrium control. Our measurements clearly reproduce the volume-scaling of τxx in confined CsPbBb QDs. However, the scaling factor γ(0.085 ± 0.001 ps/nm^3) is one order of magnitude lower than that reported for CdSe and PbSe QDs (1.00 ± 0.05 ps/nm^3), suggest!ng unique mechanisms enhancing Auger recombination rate in perovskite NCs. | Yulu Li Tao Ding Xiao Luo Zongwei Chen Xue Liu Xin Lu Kaifeng Wu | 2019 | Nano Research2019，12，3： | 4 |
| 16 | First experimental constraints on WIMP couplings in the effective field theory framework from CDEX显示文摘We present weakly interacting massive particles(WIMPs) search results performed using two approaches of effective field theory from the China Dark Matter Experiment(CDEX), based on the data from both CDEX-1B and CDEX-10 stages. In the nonrelativistic effective field theory approach, both time-integrated and annual modulation analyses were used to set new limits for the coupling of WIMP-nucleon effective operators at 90% confidence level(C.L.) and improve over the current bounds in the low mχregion. In the chiral effective field theory approach, data from CDEX-10 were used to set an upper limit on WIMP-pion coupling at 90% C.L. We for the first time extended the limit to the m_(χ)<6 GeV/c^(2) region. | Yi Wang Zhi Zeng Qian Yue LiTao Yang KeJun Kang YuanJing Li Mehment Agartioglu HaiPeng An JianPing Chang JingHan Chen YunHua Chen JianPing Cheng Cheng Yi Chiang WenHan Dai Zhi Deng ChangHao Fang XinPing Geng Hui Gong QiuJu Guo XuYuan Guo HongJian He Li He ShengMing He JinWei Hu TuChen Huang HanXiong Huang HaiTao Jia LiPing Jia Xi Jiang HauBin Li JianMin Li Jin Li MingXuan Li RenMingJie Li Xia Li YuLan Li Bin Liao FongKay Lin ShinTed Lin ShuKui Liu YanDong Liu Yu Liu YuanYuan Liu ZhongZhi Liu Hao Ma YuCai Mao QiYuan Nie JinHua Ning Hui Pan NingChun Qi Jie Ren XiChao Ruan ChangSong Shang Vivek Sharma Ze She Lakhwinder Singh Monoj Kumar Singh TianXi Sun ChangJian Tang WeiYou Tang Yang Tian GuangFu Wang Li Wang Qing Wang Yu Chen Wang YunXiang Wang Zhen Wang Henry Tsz-King Wong ShiYong Wu YuCheng Wu HaoYang Xing Yin Xu Tao Xue YuLu Yan Nan Yi ChunXu Yu HaiJun Yu JianFeng Yue Ming Zeng BingTao Zhang Lei Zhang FengShou Zhang ZhenYu Zhang KangKang Zhao MingGang Zhao JiFang Zhou ZuYing Zhou JingJun Zhu | 2021 | Science China(Physics,Mechanics & Astronomy)2021，64，8： | 3 |
| 17 | Mutations in EZH2 are associated with poor prognosis for patients with myeloid neoplasms显示文摘EZH2 is a component of the polycomb repressive complex 2(PRC2),which is a highly conserved histone methyltransferase that methylates lysine 27 of histone 3.EZH2 mutations are associated with oncogenesis and progression of cancers.However,the relationship between the clinical outcome of patients with myeloid malignancies and EZH2 mutations is controversial.Therefore,we performed a meta-analysis of 8 studies(n Z 2243 patients)that evaluates the correlation between EZH2 mutations and overall survival(OS)in patients with myeloid neoplasms.EZH2 mutations were associated with significantly worse OS(hazard ratio[HR]Z 2.37,95%confidential interval(CI),1.48e3.79).In a word,EZH2 mutations indicate a poor prognosis for patients with myeloid neoplasms. | Qi Zhang Qi Han Jie Zi Jinlong Ma Huihui Song Yulu Tian Mary McGrath Chunhua Song Zheng Ge | 2019 | Genes & Diseases2019，6，3： | 3 |
| 18 | A study of peroxyacetyl nitrate at a rural site in Beijing based on continuous observations from 2015 to 2019 and the WRFChem model显示文摘Peroxyacetyl nitrate(PA N)is one of the most important photochemical pollutants and has aroused much concern in China in recent decades.However,few studies described the long-term variations in PAN in China.In this study,we continuously monitored the PAN,03 and NOx concentrations at a regional background site near Beijing from August 2015 to February 2019.Based on the observed concentrations and climate data,w e analyzed the seasonal PAN variations.The results revealed that the monthly mean PAN concentration ranged from 0.33-2.41 ppb,with an average value of 0.94 ppb.The PAN concentration exhibited a distinct seasonal variation,with high values in spring and low values in winter.After analyzing the corresponding meteorological data,we found that stronger ultraviolet(UV)radiation,a relatively longer lifetime and a higher background PAN concentration contributed to the high PAN concentrations in spring.In addition,with the utilization of the WRF-Chem(Weather Research and Forecasting with Chemistry)model,the cause of the extremely high PAN concentration in spring 2018 wa s determined.The model results demonstrated that an anomalously low pressure and the southwesterly winds in northern China might be the main causes of the increased PAN concentration in Beijing and its surrounding area in spring 2018. | Yulu Qiu Zhiqiang Ma Weili Lin Weijun Quan Weiwei Pu Yingruo Li Liyan Zhou Qingfeng Shi | 2020 | Frontiers of Environmental Science & Engineering2020，14，4： | 3 |
| 19 | Fe, V-co-doped C_(2)N for electrocatalytic N_(2)-to-NH_(3) conversion显示文摘Designing providential catalyst is the key to drive the electrochemical nitrogen reduction reactions(NRR),which is referring to multiple intermediates and products. By means of density functional theory(DFT)calculations, we studied heteronuclear bi-atom electrocatalyst(HBEC) for NRR. Our results revealed that compared to homonuclear bi-atom electrocatalyst(Fe_2@C_2N, V_2@C_2N), Fe, V-co-doped C_2N(Fe V@C_2N)had a smaller limiting potential of-0.17 V and could accelerate N_2-to-NH_3 conversion through the enzymatic pathway of NRR. Importantly, N–N bond length monotonically increases with increasing the Bader charges of adsorbed N_2 molecule but decreases with increasing the Bader charge difference of two adsorbed N atoms. Additionally, the Fe V@C_2N could suppress the production of H_2 by the preferential adsorption and reduction of N_2 molecule. Thus, the as-designed HBEC may have the outstanding electrochemical NRR performance. This work opens a new perspective for NRR by HBECs under mild conditions. | Zengxi Wei Jian He Yulu Yang Zhenhai Xia Yuezhan Feng Jianmin Ma | 2021 | Journal of Energy Chemistry2021，30，2： | 3 |
| 20 | Community-Based Management and Treatment Services for Psychosis-China, 2019显示文摘Introduction:Community-based services for psychosis are an important part of mental health services in China.We analyzed community-based follow-up and treatment services for psychosis in China in 2019 to provide evidence for policymaking and services delivering.Methods:Data from the National Information System for Psychosis were used to analyze usage of the information system and the registration,management,and treatment situation of patients with psychosis in China in 2019 and compared the results of 2019 with that of 2018.Results:In 2019,100%of cities and counties used the information system and 6,230,157 patients were registered.In 2019,there were 5,944,724 registered patients(94.05%)in China under community-based follow-up services and 5,375,252 patients(85.04%)had regular follow-ups;5,295,657 patients(83.78%)were treated by taking antipsychotics and 3,354,251(53.07%)patients took medication regularly;4,974,314 patients at home(87.81%)were in stable condition;and there was a significant difference in patients’stable condition and medication-taking rates among eastern,central,and western regions(p<0.05).Compared with 2018,the nationwide regular management rate,medication-taking rate,regular medication-taking rate,and patients’stable rate increased by 2.35%,2.48%,11.29%,and 7.21%respectively.Conclusions and Implications for Public Health Practice:Compared with 2018,the level of management and treatment improved significantly but still needs to be further strengthened,especially in western China. | Miaomiao Zhao Ning Ma Xun Wang Xiamin Wu Wufang Zhang Runzi Chen Yulu Wang Lili Guan Hong Ma Xin Yu Lin Lu | 2020 | China CDC weekly2020，2，41： | 3 |
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