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| 1 | Past,present,and future of biochar显示文摘After entering the twenty-first century,biochar has become a focal point of multidisciplinary research because of its special characteristics,broad application,and promising development prospects.Basic and applied research on the application of biochar in the areas of agriculture,environment,and energy have increased dramatically in the face of food security,environmental pollution,and energy shortage.Although there are some disputes about biochar research,many studies have demonstrated the importance of biochar research from the perspective of scientific advancement and practical application.This paper briefly recalls the history of biochar application;introduces research progress on the basic characteristics of biochar and its associated production technologies;summarizes the research status and existing problems of biochar application in the areas of agriculture,environment,and energy;and analyzes the potential problems and development trends of biochar research in the future. | Wenfu Chen Jun Meng Xiaori Han Yu Lan Weiming Zhang | 2019 | Biochar2019，1，1： | 66 |
| 2 | Optimization design and test of rice plug seedling transplanting mechanism of planetary gear train with incomplete eccentric circular gear and non-circular gears显示文摘In order to solve the problem of the high-speed mechanized transplanting of rice plug seedlings,the design requirements of transplanting mechanism for rice plug seedlings were analyzed and a kind of rice plug seedling transplanting mechanism of planetary gear train based on the drive with incomplete eccentric circular gear and non-circular gears was designed innovatively.The laboratory kinematics was examined.The working principle of the transplanting mechanism for rice plug seedlings was studied,kinematics analysis of the transplanting mechanism was carried out and its kinematic model was set up.A human-computer interaction optimization method was used to optimize the parameters of the transplanting mechanism.The computer aided analysis and optimization software of the transplanting mechanism based on Visual Basic 6.0 was developed.Through analyzing the influence of design variables on the optimization objectives of the transplanting mechanism,a set of parameters of the transplanting mechanism which meet the requirements of transplanting trajectory and posture for transplanting rice seedlings were obtained by means of human-computer interaction.The structure of the transplanting mechanism was designed according to this set of parameters,and its virtual prototype and physical prototype were set up and manufactured,respectively.The kinematic simulation test and high-speed photography kinematic test of the transplanting mechanism were conducted to obtain its kinematic performances,such as transplanting trajectory and posture.The results of bench test,simulation analysis and theoretical analysis were almost in agreement,which verified the correctness of the theoretical model and design results of the transplanting mechanism,indicating that the optimized transplanting mechanism can satisfy the requirements of transplanting rice seedlings and be applied in the rice plug seedling transplanter. | Ye Bingliang Yi Weiming Yu Gaohong Gao Yang Zhao Xiong | 2017 | International Journal of Agricultural and Biological Engineering2017，10，6： | 31 |
| 3 | Coupling of wave and current numerical model with unstructured quadtree grid for nearshore coastal waters显示文摘This paper presents 2D wave-current interaction model for evaluating nearly horizontal wave-induced currents in the surf-zone and coastal waters.The hydrodynamic model is the two-dimensional depth-averaged nonlinear shallow water equations by using an unstructured non-staggered and multiple-level quadtree rectangular mesh,this mesh information is stored in simple data structures and it is easy to obtain a locally high resolution for important region.The intercell fluxes are computed based on the HLL(Harten-Lax-van Leer) approximate Riemann solver with shock capturing capability for computing the dry-to-wet interface of coastal line.The effects of pressure and gravity are included in source term in the model,this treatment can simplify the computation and eliminate numerical imbalance between source and flux terms.The wave model readily provides the radiation stresses that represent the shortwave-averaged forces in a water column for the hydrodynamic model and the wave model takes into account the effect of wave-induced nearshore currents and water level.The coupling model is applied to verify different experimental cases and real life case of considering the wave-current interaction.The calculated results agree with analytical solution,experimental and field data.The results show that the modeling approach presented herein should be useful in simulating the nearshore processes in complicated natural coastal domains. | ZHANG MingLiang WU WeiMing LIN LiHua YU JiangNan | 2012 | Science China(Technological Sciences)2012，55，2： | 10 |
| 4 | Development of the straw biochar returning concept in China显示文摘Biochar produced from straw has been shown to improve soil physicochemical properties.This review introduces the fundamental concepts,the broad applications,and underlying theory of straw biochar returning.Current developments in biochar industry and the production practices prevalent among enterprises in China are critiques.This review analyzes current knowledge gaps,challenges,and opportunities in the industrial application of straw biochar returning.Biochar standards,the quantitative and qualitative analysis methods for biochar,and high-value-added products that are based on biochar are critically examined with goal of providing recommendations for future studies.We propose production and modification of biochar that is application oriented to enhance its fitness for purpose as well as long-term and large-space-scale field study to better understand its impact on soil properties and ecotoxicology.Finally,we make prospects for the future development of SBR,including constructing a standard system about straw biochar returning and promoting self-discipline of biochar industry and the establishment of a biochar-based agricultural production model. | Jun Meng Tianyi He Edmond Sanganyado Yu Lan Weiming Zhang Xiaori Han Wenfu Chen | 2019 | Biochar2019，1，2： | 9 |
| 5 | Platelet function monitoring guided antiplatelet therapy in patients receiving high-risk coronary interventions显示文摘 | Xu Li Wang Lefeng Yang Xinchun Li Kuibao Sun Hao Zhang Dapeng Wang Hongshi Li Weiming Ni Zhuhua Xia Kun Liu Yu | 2014 | Chinese Medical Journal2014，，19： | 8 |
| 6 | Assessment of the immune responses to Treponema pallidum Gpd DNA vaccine adjuvanted with IL-2 and chitosan nanoparticles before and after Treponema pallidum challenge in rabbits显示文摘Syphilis is a multistage,sexually transmitted disease caused by the spirochete,Treponema pallidum(Tp).A significantly high incidence of syphilis has been reported in several countries,including China,and there is an urgent need for the development of efficacious vaccines against syphilis.DNA vaccines are a major breakthrough in the field of vaccination with several advantages over traditional vaccines.Animal model studies of Tp DNA vaccines have not been reported elsewhere but our previous reports describe the development of a single-gene Tp DNA vaccine and preclinical immunization study.In this study,chitosan(CS) nanoparticles were used as a vector and an interleukin-2 expression plasmid(pIL-2) as an adjuvant to enhance a TpGpd DNA vaccine candidate(pTpGpd) in a rabbit Tp skin challenge model.At week 8 after the first immunization,three rabbits from each group were used to determine cytokine measurements and spleen lymphocyte proliferation assay.pTpGpd in combination with pIL-2 wrapped with CS led to the greatest enhancement of anti-TpGpd antibodies and T-cell proliferation.During infection,levels of anti-TpGpd antibodies and T-cell proliferation were measured.Both the serum special IgG and IL-2,interferon-γ were significantly increased by the co-injection of the IL-2 plasmid compared with the injection of TpGpd DNA alone(P<0.05).Furthermore,IL-2 plasmid coinjection efficiently enhanced the antigen-specific lymphocyte proliferation response.Additionally,the ratios of positive skin lesions and ulcer lesions in groups immunized with pTpGpd were significantly lower than those of the pIL-2,CS or pIL-2 mixed with CS control groups(P<0.001).CS vectored and pIL-2 adjuvanted pTpGpd immunized animals exhibited the lowest rates of positive skin tests(8.33%) and ulcer lesions(4.17%) and the fastest recovery(42 d).These experiments indicate that co-injection of a pIL-2 plasmid with pTpGpd DNA vaccine wrapped with CS can significantly strengthen the long-term stability of immune response during infection,efficiently improve the protective effect against T.pallidum spirochetes infection and attenuate syphilitic lesion development. | ZHAO FeiJun ZHANG XiaoHong LIU ShuangQuan ZENG TieBing YU Jian GU WeiMing ZHANG YueJun CHEN Xi WU YiMou | 2013 | Science China(Life Sciences)2013，56，2： | 8 |
| 7 | Whole-genome sequencing provides insights into the genetic diversity and domestication of bitter gourd(Momordica spp.)显示文摘Bitter gourd(Momordica charantia)is a popular cultivated vegetable in Asian and African countries.To reveal the characteristics of the genomic structure,evolutionary trajectory,and genetic basis underlying the domestication of bitter gourd,we performed whole-genome sequencing of the cultivar Dali-11 and the wild small-fruited line TR and resequencing of 187 bitter gourd germplasms from 16 countries.The major gene clusters(Bi clusters)for the biosynthesis of cucurbitane triterpenoids,which confer a bitter taste,are highly conserved in cucumber,melon,and watermelon.Comparative analysis among cucurbit genomes revealed that the Bi cluster involved in cucurbitane triterpenoid biosynthesis is absent in bitter gourd.Phylogenetic analysis revealed that the TR group,including 21 bitter gourd germplasms,may belong to a new species or subspecies independent from M.charantia.Furthermore,we found that the remaining 166 M.charantia germplasms are geographically differentiated,and we identified 710,412,and 290 candidate domestication genes in the South Asia,Southeast Asia,and China populations,respectively.This study provides new insights into bitter gourd genetic diversity and domestication and will facilitate the future genomics-enabled improvement of bitter gourd. | Junjie Cui Yan Yang Shaobo Luo Le Wang Rukui Huang Qingfang Wen Xiaoxia Han Nansheng Miao Jiaowen Cheng Ziji Liu Changyuan Zhang Chengcheng Feng Haisheng Zhu Jianwen Su Xinjian Wan Fang Hu Yu Niu Xiaoming Zheng Yulan Yang Dai Shan Zhensheng Dong Weiming He Narinder P.S.Dhillon Kailin Hu | 2020 | Horticulture Research2020，7，1： | 7 |
| 8 | Resveratrol induces AMPK and mTOR signaling inhibition-mediated autophagy and apoptosis in multiple myeloma cells显示文摘Resveratrol,a natural compound extracted from the skins of grapes,berries,or other fruits,has been shown to have anti-tumor effects against multiple myeloma(MM)via promoting apoptosis and inhibiting cell viability.In addition to apoptosis,autophagy also plays a significant role in anti-tumor effects.However,whether autophagy is involved in anti-MM activity of resveratrol remains unclear.In this study,human MM cell lines U266,RPMI-8226,and NCI-H929 were treated with resveratrol.Cell Counting Kit-8 assay and colony formation assay were used to measure cell viability.Western blot analysis was used to detect apoptosis-and autophagy-associated proteins.3-Methyladenine(3-MA)was applied to inhibit autophagy.Results showed that resveratrol inhibited cell viability and colony formation via promoting apoptosis and autophagy in MM cell lines U266,RPMI-8226,and NCI-H929.Resveratrol promoted apoptosis-related proteins,Caspase-3 activating poly-ADP-ribose polymerase and Caspase-3 cleavage,and decreased the protein level of Survivin in a dose-dependent manner.Additionally,resveratrol upregulated the levels of LC3 and Beclin1 in a dose-dependent way,indicating that autophagy might be implicated in anti-MM effect of resveratrol.Furthermore,3-MA relieved the cytotoxicity of resveratrol by blocking the autophagic flux.Resveratrol increased the phosphorylation of adenosine monophosphate(AMP)-activated protein kinase and decreased the phosphorylation of mammalian target of rapamycin(mTOR)and its downstream substrates p70S6K and 4EBP1 in a dose-dependent manner,leading to autophagy.Therefore,our results suggest that resveratrol exerts anti-MM effects through apoptosis and autophagy,which can be used as a new therapeutic strategy for MM in clinic. | Ruye Ma Dandan Yu Yu Peng Hongfei Yi Yingcong Wang Taofang Cheng Bingqing Shi Guang Yang Weiming Lai Xiaosong Wu Ye Lu Jumei Shi | 2021 | Acta Biochimica et Biophysica Sinica2021，53，6： | 7 |
| 9 | Mitochondrial DNA A1555G mutation screening using a testing kit method and its significance in preventing aminoglycoside-related hearing loss显示文摘To report a new screening method for mitochondrial DNA 1555A→G mutation and the results of genotype analysis in 19 maternal inherited deafness pedigrees. Method Five hundred and forty-six non-syndromic neuro-sensory hearing loss patients were tested for 1555A→G mutation using a new compact testing kit, which allows clear distinction between wild type and 1555 A→G mutated mtDNAs. Results Nineteen subjects among the 546 patients (3.48%) were found to carry mtDNA A1555G mutation. The results were confirmed by sequencing in an ABI 3100 Avant sequencer. Conclusions Maternal inherited deafness families are a frequently seen in outpatient group. The detection of mtDNA 1555 A→G mutation with a low cost, ready to use detection kit is needed and suitable in China for large scale screening and preventive testing before usage of aminoglycoside antibiotics. | LIU Xin,1 DAI Pu,1* HUANG Deliang,1 YUAN Huijun,1 LI Weiming,1 YU Fei,1 ZHANG Xin,1 KANG Dongyang,1 CAO Juyang,1 YANG Weiyan,1 HAN Dongyi,1 JIN Zhengce2, GUAN Minxin3 1. Department of Otolaryngology, Chinese PLA General Hospital, Beijing, China2. Weihai Aomaier Gene Technological CO.,LTD.,Weihai,Shandong 264200, China.3. Division and Program in Human Genetics and Center for Hearing and Deafness Research, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, USA | 2006 | Journal of Otology2006，1，1： | 7 |
| 10 | Optimization of variables for maximizing efficacy and efficiency in aerial spray application to cotton using unmanned aerial systems显示文摘Aerial spraying can support efficient defoliation without crop contact.With the recent introduction to unmanned aerial system(UAS)for aerial spraying in China,there is a need to determine the optimum application variables to achieve high efficacy and efficiency with low costs.The present research involved field studies across two annual cotton production seasons in North Xinjiang,China.Four factors,including volume rate(A),tank mix including spray adjuvants(B),flight altitude(C),flight speed(D)and three levels of L9(3^(4))orthogonal arrays were carried out to optimize the application parameters for three types of UASs.These included different numbers of rotors as follows:four-rotors,six-rotors and eight-rotors.Spray coverage,distribution uniformity(coefficient of variation(CV)of droplet coverage),rates of cotton defoliation and boll opening,application efficiency and cost were measured and assessed.Results showed that:(1)the rates of defoliation and boll opening by aerial cotton defoliant application could meet the requirement of cotton mechanized harvesting;(2)the optimal scenario for the three UASs was A_(3)B_(2)C_(1)D_(3),Volume rate(A3):48 L/hm^(2);Tank mix and concentration(B_(2)):(Tuotulong 225+Sujie 750+Ethephon 2250)mL/hm^(2),Flight altitude(C_(1)):1.5 m,and Flight speeds(D_(3))for unmanned helicopters with four-rotors,six-rotors and eight-rotors were 3.12 m/s,2.51 m/s and 3.76 m/s,respectively.These results can provide guidance for cotton defoliant aerial spraying in China using UAS. | Juan Liao Ying Zang Xiwen Luo Zhiyan Zhou Yubin Lan Yu Zang Xiuyan Gu Weiming Xu Andrew John Hewitt | 2019 | International Journal of Agricultural and Biological Engineering2019，12，2： | 6 |
| 11 | CATALYTIC PERFORMANCE OF Ni/ZrO2 CATALYSTS FOR CH4 PARTIAL OXIDATION显示文摘CATALYTICPERFORMANCEOFNi/ZrO2CATALYSTSFORCH4PARTIALOXIDATION*ZhangYu,MaZifeng(DepartmentofChemicalEnginecring,SouthChinaUnive... | Zhang Yu Lin Weim | 1996 | 催化学报1996，17，5： | 5 |
| 12 | Multistage analysis method for detection of effective herb prescription from clinical data显示文摘为特定的疾病条件或特别的耐心的组决定有效繁体中文药(TCM ) 治疗是因为复杂个性化的表明,在真实世界的病人和在临床的背景规定的个性化的联合治疗要求调查的一个困难的问题。在这研究,集成倾向大小写匹配的一个多级式的分析方法,复杂网络分析,和植物给了丰富分析被建议为特别疾病识别有效植物药方(例如,失眠) 。首先,匹配的倾向大小写被使用匹配临床的盒子。然后,核心网络抽取和植物集合丰富被联合检测核心有效植物药方。基于有效性的相互的信息被用来检测强壮的 herbsymptom 关系。这个方法在一个 TCM 临床的数据集合上被使用, 955 个病人从设计得好的观察研究收集了。结果与更高的有效性率揭示了那组植物药方(76.9% 对 42.8% 为匹配的样品;94.2% 对 84.9% 为所有样品) 与原版相比,药方被发现。有症状表明的特别的耐心的组也被识别帮助调查有效植物药方的指示。 | Kuo Yang Runshun Zhang Liyun He Yubing Li Wenwen Liu Changhe Yu Yanhong Zhang Xinlong Li Yan Liu Weiming Xu Xuezhong Zhou Baoyan Liu | 2018 | Frontiers of Medicine2018，12，2： | 5 |
| 13 | Haplotype variations in QTL for salt tolerance in Chinese wheat accessions identified by marker-based and pedigree-based kinship analyses显示文摘Most modern wheat cultivars were selected on the basis of yield-related indices measured under optimal fertilizer and irrigation inputs.With climate change,land degradation and salinity caused by sea water encroachment,wheat is increasingly subjected to environmental stress.Moreover,expanding urbanization increasingly encroaches upon prime agricultural land in countries like China,and alternative cropping areas must be found.Some of these areas have moderate constraining factors,such as salinity.Therefore,it is important to investigate whether current genetic materials and breeding procedures are maintaining adequate variability to address future problems caused by abiotic stress.In this study,a panel of 307 wheat accessions,including local landraces,exotic cultivars used in Chinese breeding programs and Chinese cultivars released during different periods since1940,were subjected to a genome-wide association study to dissect the genetic basis of salinity tolerance.Both marker-based and pedigree-based kinship analyses revealed that favorable haplotypes were introduced in some exotic cultivars as well as a limited number of Chinese landraces from the 1940 s.However,improvements in salinity tolerance during modern breeding are not as obvious as that of yield.To broaden genetic diversity for increasing salt tolerance,there is a need to refocus attention on local landraces that have high degrees of salinity tolerance and carry rare favorable alleles that have not been exploited in breeding. | Shizhou Yu Jianhui Wu Meng Wang Weiming Shi Guangmin Xia Jizeng Jia Zhensheng Kang Dejun Han | 2020 | The Crop Journal2020，8，6： | 4 |
| 14 | Bridging properties of the debonded interface with frictional sliding显示文摘模仿摩擦衔接的性质的一个理论模型被介绍,纤维和矩阵的相对完美的压力解决方案被获得。在界面的 debonding 的过程基于精力平衡,为精力版本率 G 的表情被导出探索界面的破裂性质。由介绍界面的 debonding 标准 G≥Γ i , 组成的关系也是的为决定批评 debond 长度被建议并且衔接的一个方法获得了。数字计算为增强纤维的合成 SCS-6/T i -6Al-4V 和结果也与使用另外的存在模型获得的那些相比。 | LIU Pengfei TAO Weiming YU Xuezhong GUO Yimu | 2006 | Progress in Natural Science:Materials International2006，16，2： | 4 |
| 15 | Biochar can Increase Chinese Cabbage(Brassica oleracea L.)Yield,Decrease Nitrogen and Phosphorus Leaching Losses in Intensive Vegetable Soil显示文摘There are few evidences on the effect of biochar on vegetable yield,nitrogen(N)and phosphorus(P)leaching losses under intensive vegetable production soil.The current field plot scale study evaluated responses of Chinese cabbage(Brassica oleracea L.)yield,N and P leaching losses using five N treatments of common N application rate according to local farmers’practice(N100%),reducing 20%or 40%N fertilizer(N80%and N60%),and reducing 40%N fertilizer but incorporating 10 or 20 t/ha biochar(N60%+BC10 and N60%+BC20).Results showed that N80%and N60%decreased both the cabbage economic and leaf yields by 6.8%-36.3%and 27.4%-37.7%,respectively.Incorporation of biochar with reduced N fertilizer rates improved the cabbage yield,in particular the N60%+BC20 matched the yield that observed in N100%treatment.Enhanced N and P uptake capacities of cabbage shoot probably contributed the higher vegetable production under both biochar amendment schemes.Biochar application mitigated the NH_(4)^(+)-N and total P leaching losses by 20%-30%and 29%-32%,respectively,compared with their counterpart treatment N60%.Nevertheless,biochar exerted no influence on the NO_(3)^(-)-N leaching.In addition,soil organic matter content was recorded with 7.4%-28.7%higher following 10-20 t/ha biochar application.In conclusion,biochar application can increase economic yield of cabbage via increasing N and P use efficiency,decrease N and P leaching losses,and improve soil quality in an intensive vegetable production system. | Haijun Sun Paramsothy Jeyakumar Hongdong Xiao Xuewen Li Jiayou Liu Min Yu Prabal Bir Jung Rana Weiming Shi | 2022 | Phyton-International Journal of Experimental Botany2022，91，1： | 3 |
| 16 | White blood cell count and the incidence of hyperuricemia:insights from a community-based study显示文摘Hyperuricemia(HUA)is a risk factor for chronic kidney disease(CKD).The relationship between HUA and white blood cell(WBC)count remains unknown.A sampling survey for CKD was conducted in Sanlin community in 2012 and 2014.CKD was defined as proteinuria in at least the microalbuminuric stage or an estimated GFR of 60 mL/(min·1.73 m2).HUA was defined as serum uric acid>420µmol/L in men and>360µmol/L in women.This study included 1024 participants.The prevalence of HUA was 17.77%.Patients with HUA were more likely to have higher levels of WBC count,which was positively associated with HUA prevalence.This association was also observed in participants without CKD,diabetes mellitus,hyperlipidemia,or obesity.Multivariate logistic regression analysis showed that WBC count was independently associated with the risk for HUA in male and female participants.Compared with participants without HUA,inflammatory factors such as high-sensitivity C-reactive protein,tumor necrosis factor-α,and interleukin 6 increased in participants with HUA.Hence,WBC count is positively associated with HUA,and this association is independent of conventional risk factors for CKD. | Jian Liu Pingyan Shen Xiaobo Ma Xialian Yu Liyan Ni Xu Hao Weiming Wang Nan Chen | 2019 | Frontiers of Medicine2019，13，6： | 3 |
| 17 | Uniform single atomic Cu_(1)-C_(4)sites anchored in graphdiyne for hydroxylation of benzene to phenol显示文摘For single-atom catalysts(SACs),the catalyst supports are not only anchors for single atoms,but also modulators for geometric and electronic structures,which determine their catalytic performance.Selecting an appropriate support to prepare SACs with uniform coordination environments is critical for achieving optimal performance and clarifying the relationship between the structure and the property of SACs.Approaching such a goal is still a significant challenge.Taking advantage of the strong d-πinteraction between Cu atoms and diacetylenic in a graphdiyne(GDY)support,we present an efficient and simple strategy for fabricating Cu single atoms anchored on GDY(Cu_(1)/GDY)with uniform Cu_(1)-C_(4)single sites under mild conditions.The Cu atomic structure was confirmed by combining synchrotron radiation X-ray absorption spectroscopy,X-ray photoele ctron spectroscopy and density functional theory(DFT)calculations.The as-prepared Cu1/GDY exhibits much higher activity than state-of-the-art SACs in direct benzene oxidation to phenol with H_(2)O_(2)reaction,with turnover frequency values of 251 h^(-1)at room temperature and 1889 h^(-1)at 60℃,respectively.Furthermore,even with a high benzene conversion of86%,high phenol sele ctivity(96%)is maintaine d,which can be ascribed to the hydrophobic and oleophyllic surface nature of Cu1/GDY for benzene adsorption and phenol desorption.Both experiments and DFT calculations indicate that Cu_(1)-C_(4)single sites are more effective at activating H_(2)O_(2)to form Cu=O bonds,which are important active intermediates for benzene oxidation to phenol. | Jia Yu Changyan Cao Hongqiang Jin Weiming Chen Qikai Shen Peipei Li Lirong Zheng Feng He Weiguo Song Yuliang Li | 2022 | National Science Review2022，9，9： | 3 |
| 18 | Preparation of protein-loaded microspheres with size ≤ 10 μm by electrostatic droplet generation technology显示文摘The development of non-injection route for protein drugs, especially oral administration, has been the main focus of controlled release of drugs. To overcome obstacles unsolved such as enzyme degradation and penetration barrier of intestinal epi- thelium, technologies using microspheres as carrier of protein drugs have been proven potential to realize oral administration. It has been demonstrated that microspheres can not only protect proteins, but also facilitate the penetration and absorption through Peyer’s patches when the size is smaller than 10 μm. Therefore, the objective of this paper is to prepare protein-loaded microspheres with size ≤ 10 μm. Electrostatic droplet generation technology was used with insulin and hemoglobin as drug models and so- dium alginate as microsphere material. By decreas- ing the surface tension of feed solution by adding surfactant, and improving electric field distribution by changing the shape of container and electrode for gelation solution, protein-loaded microspheres with mean size less than 10 μm were successfully pro- duced through needle with diameter of 400 μm. The microspheres showed good sphericity and narrow size distribution. The mean standard variance of size distribution was 1.61. The encapsulation efficiency of proteins was over 70%. Moreover, the significance analysis of factors influencing the size of protein loaded microspheres was carried out through or- thogonal experiments, which showed that output voltage (U), needle diameter (D) and the distance between needle tips to the surface of gelation solu- tion (δ ) influenced significantly the size of micro-spheres. Finally, the statistic analysis showed that when confidence level was α=0.05, and α=0.1, con- fidence interval of microsphere size can be (6.2545, 10.1735) and (6.6022, 9.8258) correspondingly, suggesting that there is good repeatability and reli- ability for improving electrostatic droplet generation technology to prepare protein-loaded microspheres with size ≤10 μm. | XUE Weiming LIU Xiudong YU Weiting MA Xiaojun | 2006 | Chinese Science Bulletin2006，51，3： | 3 |
| 19 | AI Enabled Wireless Communications with Real Channel Measurements:Channel Feedback显示文摘Artificial intelligence(AI)has shown great potential in wireless communications.AI-empowered communication algorithms have beaten many traditional algorithms through simulations.However,the existing works just use the simulated datasets to train and test the algorithms,which can not represent the power of AI in practical communication systems.Therefore,Peng Cheng Laboratory holds an AI competition,National Artificial Intelligence Competition(NAIC):AI+wireless communications,in which one of the topics is AI-empowered channel feedback system design using practical measurements.In this paper,we give a baseline neural network design,QuanCsiNet,for this competition,and the details of the channel measurements.QuanCsiNet shows excellent performance on channel feedback and the complexity of the neural networks is also given. | Jiajia Guo Xiangyi Li Muhan Chen Peiwen Jiang Tingting Yang Weiming Duan Haowen Wang Shi Jin Quan Yu | 2020 | Journal of Communications and Information Networks2020，5，3： | 2 |
| 20 | A survey of HIV infection and related high-risk factors among men who have sex with men in Suzhou,Jiangsu,China显示文摘A cross-sectional study using the snowball sampling method was conducted in May 2008 to investigate human immunodeficiency virus (HIV) infection status and related high risk factors among men who have sex with men (MSM) in Suzhou city of Jiangsu province. The researchers carried out a face-to-face questionnaire interview among MSM, and collected their blood samples to test for HIV and other sexually transmitted diseases (STDs). Among the 280 respondents, 91.1% had homosexual acts in the past 6 months and 87.5% had multiple homosexual partners; 46.4% had heterosexual sex in the past 6 months and 33.1% had multiple heterosexual partners. The rate of continued condom use was 44.3% in homosexual sex in the past 6 months, while the rate in heterosexual sex was 33.9%. Laboratory test results showed that the prevalences of HIV and syphilis were 7.1% (20/280) and 15.0% (42/280), respectively, but no HCV-positive person was found. In the multivariate logistic regression model, subjects with a monthly income of more than RMB $ 1,000 (OR=4.83,95% CI=1.44-16.22), subjects who often went to bars for sexual partners (OR=2.25, 95%CI=1.21-4.20), and subjects who had more than one sexual partner in the past 6 months (OR=0.49, 95%CI=0.25-0.97) and had sex with fixed sexual partners in the past 6 months (OR=0.42, 95%CI=0.25-0.75) were significantly associated with the rate of continued condom use in homosexual sex in the past 6 months. Unprotected sex and multiple sexual partners were more common among MSM in Suzhou city; furthermore, the prevalences of HIV infection and syphilis were relatively high. HIV preventive measures should be designed to address these risk factors and control the spread of HIV among MSM. | Hongling Bai Xiping Huan Weiming Tang Xin Chen Hongjing Yan Xiaoyan Liu Haitao Yang Zhihang Peng Xiuping Zhao Rongbin Yu Hao Yu Feng Chen | 2011 | The Journal of Biomedical Research2011，25，1： | 2 |
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