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| 1 | Potential role of strike-slip faults in opening up the South China Sea显示文摘Radiometric dates of key rock units indicate that a remnant Late Mesozoic ocean of the Huatung Basin is still preserved today east of the South China Sea(SCS).We integrate regional geology with a Cretaceous oceanic basement in the vicinity of the Huatung Basin to reconstruct the Huatung Plate east of the Eurasian continent.Results of geophysical investigations,four expeditions of deep-sea drilling and a renaissance of regional geology allow us to propose a hypothesis that the mechanism responsible for the SCS opening was raised from strike-slip fault on the east.The hypothesis suggests that the SCS opening could highly relate to the strike-slip faults inherited from Late Mesozoic structures onshore–offshore the SE Cathaysia Block to develop rhombic-shaped extensional basins en echelon on the thinned Eurasian continental crust in the Early Cenozoic.It was followed by sinistral strike-slip movements along the boundary between the Eurasian Plate and the Huatung Plate driven by oblique subduction of the Huatung Plate to the northwest coupled with slab-pull force by southward subduction of the Proto-SCS to open up the triangle-shaped oceanic East Sub-basin in the Early Oligocene(33/34 Ma).The spreading ridge then propagated southwestward in the step-over segment between the Zhongnan-Lile and the Red River strike-slip fault systems to open the triangle-shaped oceanic Southwest Sub-basin by 23 Ma.The plate boundary fault was subsequently converted into the Manila Trench when the Eocene Sierra Madre arc of the Huatung Plate had moved from the south to its present latitude by the Middle Miocene. | Chi-Yue Huang Pinxian Wang Mengming Yu Chen-Feng You Char-Shine Liu Xixi Zhao Lei Shao Guangfa Zhong Graciano P.Yumul Jr | 2019 | National Science Review2019，6，5： | 16 |
| 2 | Reprogramming of a defense signaling pathway in rough lemon and sweet orange is a critical element of the early response to‘Candidatus Liberibacter asiaticus’显示文摘Huanglongbing(HLB)in citrus infected by Candidatus Liberibacter asiaticus(CLas)has caused tremendous losses to the citrus industry.No resistant genotypes have been identified in citrus species or close relatives.Among citrus varieties,rough lemon(Citrus jambhiri)has been considered tolerant due to its ability to produce a healthy flush of new growth after infection.The difference between tolerance and susceptibility is often defined by the speed and intensity of a plant’s response to a pathogen,especially early defense responses.RNA-seq data were collected from three biological replicates of CLas-and mock-inoculated rough lemon and sweet orange at week 0 and 7 following infection.Functional analysis of the differentially expressed genes(DEGs)indicated that genes involved in the mitogen activated protein kinase(MAPK)signaling pathway were highly upregulated in rough lemon.MAPK induces the transcription of WRKY and other transcription factors which potentially turn on multiple defense-related genes.A Subnetwork Enrichment Analysis further revealed different patterns of regulation of several functional categories,suggesting DEGs with different functions were subjected to reprogramming.In general,the amplitude of the expression of defense-related genes is much greater in rough lemon than in sweet orange.A quantitative disease resistance response may contribute to the durable tolerance level to HLB observed in rough lemon. | Qibin Yu Chunxian Chen Dongliang Du Ming Huang Jiqiang Yao Fahong Yu Ronald H Brlansky Frederick G.Gmitter Jr | 2017 | Horticulture Research2017，4，1： | 5 |
| 3 | Genome resequencing and transcriptome profiling reveal structural diversity and expression patterns of constitutive disease resistance genes in Huanglongbing-tolerant Poncirus trifoliata and its hybrids显示文摘Huanglongbing(HLB)is the most destructive bacterial disease of citrus worldwide.While most citrus varieties are susceptible to HLB,Poncirus trifoliata,a close relative of Citrus,and some of its hybrids with Citrus are tolerant to HLB.No specific HLB tolerance genes have been identified in P.trifoliata but recent studies have shown that constitutive disease resistance(CDR)genes were expressed at much higher levels in HLB-tolerant Poncirus hybrids and the expression of CDR genes was modulated by Candidatus Liberibacter asiaticus(CLas),the pathogen of HLB.The current study was undertaken to mine and characterize the CDR gene family in Citrus and Poncirus and to understand its association with HLB tolerance in Poncirus.We identified 17 CDR genes in two citrus genomes,deduced their structures,and investigated their phylogenetic relationships.We revealed that the expansion of the CDR family in Citrus seems to be due to segmental and tandem duplication events.Through genome resequencing and transcriptome sequencing,we identified eight CDR genes in the Poncirus genome(PtCDR1-PtCDR8).The number of SNPs was the highest in PtCDR2 and the lowest in PtCDR7.Most of the deletion and insertion events were observed in the UTR regions of Citrus and Poncirus CDR genes.PtCDR2 and PtCDR8 were in abundance in the leaf transcriptomes of two HLB-tolerant Poncirus genotypes and were also upregulated in HLB-tolerant,Poncirus hybrids as revealed by real-time PCR analysis.These two CDR genes seem to be good candidate genes for future studies of their role in citrus-CLas interactions. | Nidhi Rawat Brajendra Kumar Ute Albrecht Dongliang Du Ming Huang Qibin Yu Yi Zhang Yong-Ping Duan Kim D Bowman Fred G Gmitter Jr Zhanao Deng | 2017 | Horticulture Research2017，4，1： | 5 |
| 4 | Study on incisional implantation of tumor cells by carbon dioxide pneumoperitoneum in gastric cancer of a murine model显示文摘 | Wang H Zheng MH Zhang HB Zhu J He JR Lu AG Ji YB Zhang MJ Jiang Y Yu BM Li HW | 1999 | World Journal of Gastroenterology1999，5，6： | 2 |
| 5 | Repairing of goat tibial bone defects with BMP-2 gene-modified tissue-engineered bone显示文摘 | Dai KR Xu XL Tang TT Zhu ZA Yu CF Lou JR Zhang XL | 2006 | 中国生物学文摘2006，20，5： | 2 |
| 6 | Gastrodia elata blume and an active component,p-Hydroxybenzyl alcohol reduce focal ischemic brain injury through antioxidant related gene expressions显示文摘 | Yu SJ Kim JR Lee CK | 2005 | Biol Pharm Bull2005，28，6： | 1 |
| 7 | Role of a STAT binding site in the regulation of the human perforin promoter显示文摘 | Yu CR Ortaldo JR Curiel RE | 1999 | J Immunol1999，162，5： | 1 |
| 8 | Hydrogen production by steam reforming glucose in supercritical water显示文摘 | Yu D Aihara M Antal Jr M J 1993 | 1993 | Energy Fuels1993，7，： | 1 |
| 9 | Management and return to play of stress fractures显示文摘 | Kaeding CC Yu JR Wright R | | 0，，06： | 1 |
| 10 | Cloning and characterization of NBS-LRR class resistance-gene candidate sequences in citrus显示文摘 | Z. Deng S. Huang P. Ling C. Chen C. Yu C. A. Weber G. A. Moore F.G. Gmitter Jr | 2000 | TAG Theoretical and Applied Genetics (-)2000，，5： | 1 |
| 11 | Phase behavior of CO2 and crude oil in low-temperature reservoirs显示文摘 | Orr F M Jr Yu A D Lien C L | 1981 | SPE Journal1981，21，4： | 1 |
| 12 | A piecewise regression analysis with automatic change-point detection显示文摘 | LI HL YU JR | 1999 | Intelligent data analysis1999，，3： | 1 |
| 13 | Identification of parasite DNA in common bile duct stones by PCR and DNA sequencing显示文摘 | Jang JS Kim KH Yu JR | 2007 | Ko rean J Parasitol2007，45，4： | 1 |
| 14 | Type I interferons protect mice against enterovirus 71 infection 显示文摘 | Liu ML Lee YP Wang YF Lei HY Liu CC Wang SM Su IJ Wang JR Yeh TM Chen SH Yu CK | 2005 | J Gen Virol2005，86，12： | 1 |
| 15 | Minimally invasive estimation of systemic vascular parameters 显示文摘 | Yu YC Boston JR Simaan MA | 2001 | Ann Biomed Eng2001，29，7： | 1 |
| 16 | An anatomic study of the S2 iliac technique for lumbopelvic screw placement显示文摘 | O′Brien JR Yu WD Bhatnagar R | 2009 | Spine2009，34，12： | 1 |
| 17 | Gastrodia elatablume and active component,p-hydroxybenzyl alcohol reduce focal ischemibrain injury through antioxidant related gene expressions显示文摘 | Yu S J Kim JR LeeC K | 2005 | BiolPharm Bull2005，28，6： | 1 |
| 18 | Clioquinol independently targets NF-kappaB and lysosome pathways in human cancer cells显示文摘 | Yu H Lou JR Ding WQ | 2010 | Anticancer Res2010，30，6： | 1 |
| 19 | Development of a membrane array-based multimarker assay for detection of circulating cancer cells in patients with non small cell lung cancer 显示文摘 | Sheu CC Yu YP Tsai JR | 2006 | Int J Cancer2006，119，6： | 1 |
| 20 | Transport approaches to the biopharmaceutical design of oral drug delivery systems: prediction of intestinal absorption显示文摘 | Yu LX Lipka E Crison JR | 1996 | Adv Drug Deliv Rev1996，19，3： | 1 |
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