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| 1 | Validity of subjective assessment as screening tool for dry eye disease and its association with clinical tests显示文摘AIM: To determine the role of subjective assessment using Mc Monnies dry eye questionnaire in diagnosing dry eye disease and its association with clinical tests.METHODS: There were 500 patients screened for dry eye using Mc Monnies dry eye questionnaire between May to October 2013 at the outpatient Department of Ophthalmology of a medical college hospital. All 500 patients were subjected to clinical tests. Dry eye was defined as having one or more symptoms often or all the time. Positive signs were if one or both eyes revealed tear film breakup time(TBUT) of ≤10s, a Schirmer test score of ≤10 mm, a Rose Bengal staining score of ≥1, a Lissamine green staining score of ≥1 or existence of meibomian gland disease(≥grade 1). Statistical analysis was performed to describe the distribution of symptoms and signs, to assess the correlations between Mc Monnies score(MS) and variable clinical signs of dry eye, and to explore the association between dry eye symptoms and variable clinical signs. Analysis was performed using software package Epi info. A Probability(P) value using Chi-square test of <0.005 was taken as significant.· RESULTS: Dry eye prevalence with symptoms(questionnaire), Schirmer test, TBUT, Rose Bengal staining and Lissamine green staining was 25.6%,15.20%, 20.80%, 23.60%, and 22.60% respectively. Among those with severe symptoms(MS>20), 75.86% had a low TBUT(<10s), 58.62% had a low Schirmer's I test(≤10 mm),86.20% had Rose Bengal staining score of ≥1, 79.31%had Lissamine green staining score of ≥1. We found statistically significant associations between positive Schirmer test and arthritis(P <0.002), dryness elsewhere(P <0.001), contact lens use(P < 0.002), systemic medication(P <0.0001), sleeping with eyes partly open(P <0.002), history of dry eyes treatment(P <0.0001),environmental factors(P <0.001), swimming(P <0.001).· CONCLUSION: Subjective assessment plays an important role in diagnosing dry eye disease. There is strong correlation between MS and Schirmer test, TBUT,Rose Bengal staining and Lissamine green staining in normal as well as marginal and pathological dry eye. | Kavita R Bhatnagar Sonali Pote Sudeep Pujari Dhiraj Deka | 2015 | International Journal of Ophthalmology(English edition)2015，8，1： | 2 |
| 2 | An expert system based algorithm for short term load forecast显示文摘 | Rahman S Bhatnagar R | 1988 | IEEE Trans on Power Systems1988，3，2： | 2 |
| 3 | Enhanced Cell Attachment to Anorganic Bone Mineral in the Presence of Synthetic Peptide Related to Collagen显示文摘 | Qian J J Bhatnagar R | 1996 | J of Biomedical Materials Research1996，31，： | 1 |
| 4 | Improved inter-ference cancellation scheme for two-user detection of alamouti code显示文摘 | Bhatnagar Manav R Are Hjrungnes | | 0，，08： | 1 |
| 5 | Differentiation of malignant and degenerative benign bone disease using Tc-99m MDP and Tc-99m citrate scintigraphy显示文摘 | Sharma R Mondal A Bhatnagar A | 1998 | Clin Nucl Med1998，23，11： | 1 |
| 6 | The nonsynchronous flow-through coil planet centrifuge without rotating seals applied to cell separation显示文摘 | Ito Y Carmeci P Bhatnagar R | 1980 | Separation Science Technol1980，15，： | 1 |
| 7 | ^99Tc^m-citrate: a new bone imaging radiopharmaceutical显示文摘 | Bhatnagar A Mishra P Sharma R | 1999 | Nucl Med Commun1999，20，11： | 1 |
| 8 | Improved nonsynchronous flow through coil planet centrifuge without rotating seals: principle and application显示文摘 | Ito Y Bramblett GT Bhatnagar R | 1983 | Separation Science Technol1983，18，： | 1 |
| 9 | Mechanism in Nb doped titania oxygen gas sensor显示文摘 | SHARMA R K BHATNAGAR M C SHARMA G L | 1998 | Sens Actuators B1998，46，： | 1 |
| 10 | Soil water movement under a single surface trickle source显示文摘 | Bhatnagar P R Chauhan H S | 2008 | Agricultural Water Management2008，95，7： | 1 |
| 11 | An anatomic study of the S2 iliac technique for lumbopelvic screw placement显示文摘 | O′Brien JR Yu WD Bhatnagar R | 2009 | Spine2009，34，12： | 1 |
| 12 | Diagnosis of atypical fibroxanthoma-a case report显示文摘 | Sharma VK Bisht D Agarwal AK Bhatnagar VB | 2002 | Indian J Pathol Microbiol2002，45，3： | 1 |
| 13 | A global solution of the ICRH problem based on the combined use of a planar coupling model and hot-plasma ray-tracing in tokamak geometry 显示文摘 | Koch R Bhatnagar V P | 1986 | Computer Physics Communication1986，4，： | 1 |
| 14 | Intradermal immunization withouter membrane protein 25 protects Balb/c mice frorrvirulent B, abortus 544 显示文摘 | Goel D Bhatnagar R | 2012 | Mol Immunol2012，51，2： | 1 |
| 15 | Third party logistics services:a Singapore perspective显示文摘 | Bhatnagar R Sohal A S Millen R | 1999 | International Journal of Physical Distribution and Logistics Management1999，29，9： | 1 |
| 16 | Development and evaluation of a novel multiplex PCR technology for molecular differential detection of bacterial respiratory disease pathogens显示文摘 | Benson R Tondella ML Bhatnagar J | 2008 | J Clin Microbiol2008，46，6： | 1 |
| 17 | Biological control of sugarcane smut (Sporisorium scitamineum) through botanicals and Trichoderma viride显示文摘 | LAL R J SINHA O K BHATNAGAR S | 2009 | Sugar Tech2009，11，4： | 1 |
| 18 | Typhoid and paratyphoid fever显示文摘 | BAHN M BAHL R BHATNAGAR S | | 0，，9497： | 1 |
| 19 | Molecular characterization of chitinase from polyphagous pest Helicoverpa armigera显示文摘 | Tarannum Ahmad R Rajagopal Raj K Bhatnagar | 2003 | Biochemical and Biophysical Research Communications2003，，1： | 1 |
| 20 | Soil water movement under a single surface trickle source显示文摘 | BHATNAGAR P R CHAUHAN H S | 2008 | Agricultural Water Man- agement2008，95，7： | 1 |
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