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| 1 | Mushroom Poisoning Outbreaks-China,2020显示文摘What is already known about this topic?Acute liver failure,rhabdomyolysis,acute renal failure,and hemolysis caused by poisonous mushrooms are the most important mushroom poisoning threats to the Chinese population.The most notorious lethal mushrooms are the species from genera Amanita,Lepiota,and Galerina that cause acute liver failure,and Russula subnigricans that leads to rhabdomyolysis.What is added by this report?In 2020,the total number of investigations reached 676,involving an estimated 102 species of poisonous mushrooms,24 of which were newly recorded in China.Gyromitra venenata was newly discovered in incidents in Yunnan and Guizhou provinces and were the first reported poisonings due to gyromitrins in China since 2000.The rare poisoning Shiitake mushroom dermatitis was recorded in China.Hemolysis poisoning caused by Paxillus involutus was recorded for the second time since the beginning of the new century,resulting in one death in Inner Mongolia Autonomous Region.What are the implications for public health practice?Promoting knowledge about safe consumption of mushrooms is essential to reduce mushroom poisonings.It is not wise to collect and eat wild mushrooms.For southwestern provinces such as Yunnan,especially,caution must be exercised with unfamiliar mushroom species. | Haijiao Li Hongshun Zhang Yizhe Zhang Jing Zhou Yu Yin Qian He Shaofeng Jiang Peibin Ma Yutao Zhang Ke Wen Yuan Yuan Nan Lang Bowen Cheng Junjia Lu Chengye Sun | 2021 | China CDC weekly2021，3，3： | 13 |
| 2 | Mushroom Poisoning Outbreaks--China,2019显示文摘What is already known about this topic?Mushroom poisoning is becoming one of the most serious food safety issues in China,which is responsible for nearly a half of all oral poisoning deaths.What is added by this report?In China,many mushrooms were previously“recorded”as poisonous.In this study,about 70 species obtained from mushroom poisoning incidents including several new records were confirmed accurately by morphological and molecular evidence in 2019,and spatial and temporal distribution characters of 13 lethal mushrooms were summarized systematically.What are the implications for public health practice?Precise and timely species identification is of pivotal importance in mushroom incidents.More efforts and cooperation are continued to be needed urgently for the governments,CDC staff,doctors and mycologists in future. | Haijiao Li Hongshun Zhang Yizhe Zhang Kaiping Zhang Jing Zhou Yu Yin Shaofeng Jiang Peibin Ma Qian He Yutao Zhang Ke Wen Yuan Yuan Nan Lang Junjia Lu Chengye Sun | 2020 | China CDC weekly2020，2，2： | 11 |
| 3 | Plasma metabolomic and lipidomic alterations associated with COVID-19显示文摘The pandemic of the coronavirus disease 2019(COVID-19)has become a global public health crisis.The symptoms of COVID-19 range from mild to severe,but the physiological changes associated with COVID-19 are barely understood.In this study,we performed targeted metabolomic and lipidomic analyses of plasma from a cohort of patients with COVID-19 who had experienced different symptoms.We found that metabolite and lipid alterations exhibit apparent correlation with the course of disease in these patients,indicating that the development of COVID-19 affected their whole-body metabolism.In particular,malic acid of the TCA cycle and carbamoyl phosphate of the urea cycle result in altered energy metabolism and hepatic dysfunction,respectively.It should be noted that carbamoyl phosphate is profoundly down-regulated in patients who died compared with patients with mild symptoms.And,more importantly,guanosine monophosphate(GMP),which is mediated not only by GMP synthase but also by CD39 and CD73,is significantly changed between healthy subjects and patients with COVID-19,as well as between the mild and fatal cases.In addition,dyslipidemia was observed in patients with COVID-19.Overall,the disturbed metabolic patterns have been found to align with the progress and severity of COVID-19.This work provides valuable knowledge about plasma biomarkers associated with COVID-19 and potential therapeutic targets,as well as an important resource for further studies of the pathogenesis of COVID-19. | Di Wu Ting Shu Xiaobo Yang Jian-Xin Song Mingliang Zhang Chengye Yao Wen Liu Muhan Huang Yuan Yu Qingyu Yang Tingju Zhu Jiqian Xu Jingfang Mu Yaxin Wang Hong Wang Tang Tang Yujie Ren Yongran Wu Shu-Hai Lin Yang Qiu Ding-Yu Zhang You Shang Xi Zhou | 2020 | National Science Review2020，7，7： | 9 |
| 4 | Mushroom Poisoning Outbreaks — China, 2021显示文摘Summary What is already known about this topic?Mushroom poisoning is one of the most serious food safety issues in China.Most poisoning incidents resulted from eating mushrooms causing gastroenteritis and psycho-neurological disorder from which patients usually could fully recover.Most deaths resulted from species causing acute liver failure and rhabdomyolysis,and the remaining deaths were attributed to acute renal failure and hemolysis.What is added by this report?In 2021,the total number of investigations was 327 from 25 provincial-level administrative divisions,involving 923 patients and 20 deaths,and the overall mortality was 2.17%.Overall,74 poisonous mushrooms causing 6 different clinical syndromes were successfully identified,15 of which were newly recorded in China as poisonous mushrooms.What are the implications for public health practice?Considering the potential huge risks for collecting and eating wild mushrooms,we strongly advise not collecting and eating unfamiliar wild mushrooms.Promoting knowledge about poisonous mushrooms is essential and urgent to reduce mushroom poisonings.Precise species identification timely after mushroom poisoning is important for appropriate diagnosis and treatment.Many deaths were ascribed to delayed hospitalization. | Haijiao Li Hongshun Zhang Yizhe Zhang Jing Zhou Yu Yin Qian He Shaofeng Jiang Peibin Ma Yutao Zhang Yuan Yuan Nan Lang Bowen Cheng Mei Wang Chengye Sun | 2022 | China CDC weekly2022，4，3： | 7 |
| 5 | Mushroom Poisoning Outbreaks -China, 2022显示文摘Mushroom poisoning has become a serious food safety issue in China.With the support of the government,over the past decade,China has gradually established a mushroom poisoning prevention and treatment system involving experts in disease prevention and control,clinical diagnosis and treatment,fungal classification,and basic medicine(1–3). | Haijiao Li Yizhe Zhang Hongshun Zhang Jing Zhou Jiaqi Liang Yu Yin Qian He Shaofeng Jiang Yutao Zhang Yuan Yuan Nan Lang Bowen Cheng Mei Wang Chengye Sun | 2023 | China CDC weekly2023，5，3： | 4 |
| 6 | Laser shock processing of 2024 -T62 aluminum alloy显示文摘 | Zhang Hong Yu Chengye | 1998 | Materials Science and Engineering1998，257，2： | 1 |
| 7 | Intricate ruled surface machining by wire-EDM 显示文摘 | Ni Zewang Liu Zhengxun Yu Chengye | 1991 | Journal of Materials Processing Technology1991，28，12： | 1 |
| 8 | The investigation of the flow characteristics of the gap in the pulse electrochemical machining (PECM)显示文摘 | Yu Chengye Liu C S Huang Yinhui | 1982 | CIRP Annals--Manufacturing Technology1982，31，1： | 1 |
| 9 | Waterborne Arsenic Poisoning Caused by Discarded Slags--Yongzhou City,Hunan Province,China,2018显示文摘What is already known about this topic?Overexposure to arsenic is toxic and affects bodily systems.In severe cases,loss of motor function and death can occur.What is added by this report?At the end of 2018,a waterborne acute arsenic poisoning event occurred in Yongzhou City of Hunan Province because arsenic-containing slags contaminated the water supply,which resulted in 10 people being poisoned.Patients were poisoned through domestic use of contaminated well water excluding drinking.What are the implications for public health practice?Clinicians should be trained to correctly and promptly identify and diagnose acute arsenic poisoning.The arsenic slags and byproducts should be strictly managed by corresponding enterprises to avoid similar poisoning incidents.When dealing with such events,water intended for domestic use should be closely monitored and environmental pollution should be assessed and controlled. | Junjia Lu Yan Lai Shaofeng Jiang Peibin Ma Lei Huang Yimei Yang Fangkun Tang Chuntao Huang Lun Hong Yu Yin Chengye Sun | 2020 | China CDC weekly2020，2，32： | 1 |
| 10 | INVESTIGATIONS ON LASER SHOCK-PROCESSING (LSP) TO IMPROVE FATIGUE LIFE OF SMALL HOLE IN AIRCRAFT STRUCTURES显示文摘 | Zhang Yongkang(Institute of Acoustics and Lab of Modern Acoustics,Nanjing University, Nanjing, China, 210093)Yu Chengye(Nanjing University of Aeronautics and Astronautics, Nanjing, China, 210016) | 1997 | Chinese Journal of Aeronautics1997，10，1： | 1 |
| 11 | Craniofacial therapy:advanced local therapies from nano-engineered titanium implants to treat craniofacial conditions显示文摘Nano-engineering-based tissue regeneration and local therapeutic delivery strategies show significant potential to reduce the health and economic burden associated with craniofacial defects,including traumas and tumours.Critical to the success of such nano-engineered non-resorbable craniofacial implants include load-bearing functioning and survival in complex local trauma conditions.Further,race to invade between multiple cells and pathogens is an important criterion that dictates the fate of the implant.In this pioneering review,we compare the therapeutic efficacy of nano-engineered titanium-based craniofacial implants towards maximised local therapy addressing bone formation/resorption,soft-tissue integration,bacterial infection and cancers/tumours.We present the various strategies to engineer titanium-based craniofacial implants in the macro-,micro-and nano-scales,using topographical,chemical,electrochemical,biological and therapeutic modifications.A particular focus is electrochemically anodised titanium implants with controlled nanotopographies that enable tailored and enhanced bioactivity and local therapeutic release.Next,we review the clinical translation challenges associated with such implants.This review will inform the readers of the latest developments and challenges related to therapeutic nano-engineered craniofacial implants. | Karan Gulati Chengye Ding Tianqi Guo Houzuo Guo Huajie Yu Yan Liu | 2023 | International Journal of Oral Science2023，15，1： | 1 |
| 12 | Intricate ruled surface machining by wire-EDM 显示文摘 | NI Zewang LIU Zhengxun YU Chengye | 1991 | Journal of Materials Processing Technology1991，28，12： | 1 |
| 13 | Laser shock processing of Holes显示文摘 | ZHANG HONG YU CHENGYE | | Surface Engineering0，22，2： | 1 |
| 14 | Laser shock- processing for fatigue and fracture resistance显示文摘 | Zhang Yongkang Zhang Shuyi Yu Chengye | 1997 | Science in China (Series E)1997，4，2： | 1 |
| 15 | Prim-O-glucosylcimifugin ameliorates aging-impaired endogenous tendon regeneration by rejuvenating senescent tendon stem/progenitor cells显示文摘Adult tendon stem/progenitor cells(TSPCs)are essential for tendon maintenance,regeneration,and repair,yet they become susceptible to senescence with age,impairing the self-healing capacity of tendons.In this study,we employ a recently developed deep-learning-based efficacy prediction system to screen potential stemness-promoting and senescence-inhibiting drugs from natural products using the transcriptional signatures of stemness.The top-ranked candidate,prim-O-glucosylcimifugin(POG),a saposhnikovia root extract,could ameliorate TPSC senescent phenotypes caused by long-term passage and natural aging in rats and humans,as well as restore the self-renewal and proliferative capacities and tenogenic potential of aged TSPCs.In vivo,the systematic administration of POG or the local delivery of POG nanoparticles functionally rescued endogenous tendon regeneration and repair in aged rats to levels similar to those of normal animals.Mechanistically,POG protects TSPCs against functional impairment during both passage-induced and natural aging by simultaneously suppressing nuclear factor-κB and decreasing mTOR signaling with the induction of autophagy.Thus,the strategy of pharmacological intervention with the deep learning-predicted compound POG could rejuvenate aged TSPCs and improve the regenerative capacity of aged tendons. | Yu Wang Shanshan Jin Dan Luo Danqing He Min Yu Lisha Zhu Zixin Li Liyuan Chen Chengye Ding Xiaolan Wu Tianhao Wu Weiran Huang Xuelin Zhao Meng Xu Zhengwei Xie Yan Liu | 2023 | Bone Research2023，11，4： | 0 |
| 16 | Mushroom Poisoning Outbreaks—China,2023显示文摘Summary What is already known about this topic?Mushroom poisoning poses a significant food safety concern in China,with a total of 196 species identified in poisoning incidents by the end of 2022.What is added by this report?In 2023,the China CDC conducted an investigation into 505 cases of mushroom poisoning spanning 24 provincial-level administrative divisions.This investigation resulted in 1,303 patients and 16 deaths,yielding a case fatality rate of 1.23%.A total of 97 mushrooms were identified as the cause of 6 distinct clinical disease types,with 12 species newly documented as poisonous mushrooms in China.What are the implications for public health practice?Close collaboration among CDC staff,physicians,and mycologists remains crucial for the control and prevention of mushroom poisoning in the future. | Haijiao Li Yizhe Zhang Hongshun Zhang Jing Zhou Zuohong Chen Jiaqi Liang Yu Yin Qian He Shaofeng Jiang Yutao Zhang Yuan Yuan Nan Lang Bowen Cheng Jiaju Zhong Zhongfeng Li Chengye Sun | 2024 | China CDC weekly2024，6，4： | 0 |
| 17 | 围炉煮茶——多功能茶炉设计显示文摘围炉煮茶,看着白烟慢慢升起,茶汤微沸,是一件很雅致的事情。这款茶炉将多种功能整合到一个以泡茶为中心的单一器具中,将明火炊具改造成电炊具,同时还可作为电加热器、电茶壶、电磁炉和照明设备等使用。茶炉将传统文化与现代科技相结合,营造出温馨的家庭生活氛围。茶炉有多种模式,可用于泡茶、加热食物和照明等各种用途。它是电磁炉、绝缘垫. | Cao Kang Huang Chengye Li Zhian Ling Junjie Liu Weirui Luo Jie Wang Huihui Wu Peng Yu Linjun | 2023 | 工业设计2023，，11： | 0 |
| 18 | Preparation and upconversion luminescence modification of YbPO4:Er3+inverse opal heterostructure显示文摘Photonic crystal heterostructures composed of YbPO_4:Er^(3+) inverse opal and polystyrene opal were prepared via a template-assisted process, which exhibited two photonic band gaps. The microstructure,phase and optical properties of photonic crystal heterostructures were investigated by x-ray diffraction,scanning electron microscopy, fluorescence spectroscopy, absorption spectroscopy, fluorescence lifetime,etc. The upconversion emission suppression caused by single photonic band gap from the following YbPO_4:Er^(3+) inverse opal or the upper opal was observed. The upconversion luminescence was strongly suppressed due to the two photonic band gap overlapping effect caused by the following YbPO_4:Er^(3+) inverse opal or the upper opal. The modified mechanisms of upconversion luminescence were discussed by the upconversion luminescence lifetime of YbPO_4:Er^(3+) photonic crystal heterostructures. The results demonstrated the modified upconversion luminescence is attributed to the photon trapping caused by Bragg reflection of photonic crystal heterostructures. | Zhuangzhuang Chai Zhengwen Yang Anjun Huang Chengye Yu Jianbei Qiu Zhiguo Song | 2017 | Journal of Rare Earths2017，35，12： | 0 |
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