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| 1 | Autophagy receptor CCDC50 tunes the STING-mediated interferon response in viral infections and autoimmune diseases显示文摘DNA sensing and timely activation of interferon(IFN)-mediated innate immunity are crucial for the defense against DNA virus infections and the clearance of abnormal cells.However,overactivation of immune responses may lead to tissue damage and autoimmune diseases;therefore,these processes must be intricately regulated.STING is the key adaptor protein,which is activated by cyclic GMP-AMP,the second messenger derived from cGAS-mediated DNA sensing.Here,we report that CCDC50,a newly identified autophagy receptor,tunes STING-directed type I IFN signaling activity by delivering K63-polyubiquitinated STING to autolysosomes for degradation.Knockout of CCDC50 significantly increases herpes simplex virus 1(HSV-1)-or DNA ligand-induced production of type I IFN and proinflammatory cytokines.Ccdc50-deficient mice show increased production of IFN,decreased viral replication,reduced cell infiltration,and improved survival rates compared with their wild-type littermates when challenged with HSV-1.Remarkably,the expression of CCDC50 is downregulated in systemic lupus erythematosus(SLE),a chronic autoimmune disease.CCDC50 levels are negatively correlated with IFN signaling pathway activation and disease severity in human SLE patients.CCDC50 deficiency potentiates the cGAS-STING-mediated immune response triggered by SLE serum.Thus,our findings reveal the critical role of CCDC50 in the immune regulation of viral infections and autoimmune diseases and provide insights into the therapeutic implications of CCDC50 manipulation. | Panpan Hou Yuxin Lin Zibo Li Ruiqing Lu Yicheng Wang Tian Tian Penghui Jia Xi Zhang Liu Cao Zhongwei Zhou Chunmei Li Jieruo Gu Deyin Guo | 2021 | Cellular & Molecular Immunology2021，18，10： | 3 |
| 2 | Impact of EV load uncertainty on optimal planning for electric vehicle charging station显示文摘With the development of electric vehicles(EV), there is a huge demand for electric vehicle charging stations(EVCS). The utilization of renewable energy sources(RES) in EVCS can not only decrease the energy fluctuation by participating in peakload reduction of the grid, but also reduce the pollution to the environment by cutting down the use of fossil fuels. In this paper,the optimal planning for grid-connected EVCS with RES is studied by considering EV load uncertainty. Nine scenarios are set based on a different characteristic of EV load to reveal the impact of EV load on net present cost(NPC) and to express the relationship between the optimal capacity and energy flow. Moreover, since electricity price also plays an important role in EVCS planning, an economic comparison between different cases with different electricity prices for peak-valley-flat period is carried out. The results reveal the economic benefits of applying RES in EVCS, and demonstrate that EV load with different characteristics would influence the capacity of each device(PV, battery, converter) in the EVCS optimal planning. | LONG YiLin LI Yong WANG YaHui CAO YiJia JIANG Lin ZHOU YiCheng DENG YouYue NAKANISHI Yosuke | 2021 | Science China(Technological Sciences)2021，64，11： | 3 |
| 3 | Imaging algorithm of multi-ship motion target based on compressed sensing显示文摘An imaging algorithm based on compressed sensing(CS) for the multi-ship motion target is presented. In order to reduce the quantity of data transmission in searching the ships on a large sea area, both range and azimuth of the moving ship targets are converted into sparse representation under certain signal basis. The signal reconstruction algorithm based on CS at a distant calculation station, and the Keystone and fractional Fourier transform(FRFT) algorithm are used to compensate range migration and obtain Doppler frequency. When the sea ships satisfy the sparsity, the algorithm can obtain higher resolution in both range and azimuth than the conventional imaging algorithm. Some simulations are performed to verify the reliability and stability. | Lin Zhang Yicheng Jiang | 2016 | Journal of Systems Engineering and Electronics2016，27，4： | 1 |
| 4 | Compact ultra-wideband rectangular aperture antenna and band-notched designs 显示文摘 | LIN Yicheng HUANG Kuanjnn | 2006 | IEEE Trans on Antennas and Propagation2006，54，11： | 1 |
| 5 | On the Ecological Restoration Mode of Urban Water Revetment Landscape显示文摘Urban waterfront revetment is a special zone between water and land,with high ecological,economic and aesthetic value. Waterfront revetment landscape is not only an important part of urban water and land ecosystems,but also an integral part of the city. Based on the current situation of ecological environment of waterfront revetment landscape,we come up with different ecological restoration modes for different types of revetment,to achieve the organic integration of waterfront revetment landscape and ecology. | Yicheng WANG Hui LIN | 2014 | Asian Agricultural Research2014，6，10： | 1 |
| 6 | Multi-relaxation time lattice Boltzmann simulations of deep lid driven cavity flows at different aspect ratios显示文摘 | Lin Lisong Chen Yicheng Lin Chaoan | 2011 | Computers and Fluids2011，45，1： | 1 |
| 7 | Electromagnetic scattering model for a tree trunk above a tilted ground plane显示文摘 | Lin Yicheng Sarabandi K | 1995 | IEEE Transactions on Geoscienee and Remote Sensing1995，33，4： | 1 |
| 8 | A Monte Carlo Coherent Scattering Model for Forest Canopies Using Fractal-Generated Trees显示文摘 | Lin Yicheng Sarabandi K | 1999 | IEEE Trans on Geosci Remote Sensing1999，37，1： | 1 |
| 9 | A particle Swarm optmization approach based on Monte Carlo simulation for solving the complex network reliability problem显示文摘 | YE Weichang LIN Yicheng YU Yingchung | 2010 | IEEE Transactions on Reliability2010，59，1： | 1 |
| 10 | Nitrilotriacetic acid-coated magnetic nanoparticles as affinity probes for enrichment of histidine-tagged proteins and phosphorylated peptides 显示文摘 | Li Yicheng Lin Yashiuan Tsai Pei Jane | 2007 | Anal Chem2007，79，： | 1 |
| 11 | A robust video text detection approach using SVM显示文摘 | WEI Yicheng Lin Changhong | 2012 | Expert Systems with Applications2012，39，10： | 1 |
| 12 | Data-driven Two-step Day-ahead Electricity Price Forecasting Considering Price Spikes显示文摘In the electricity market environment,electricity price forecasting plays an essential role in the decision-making process of a power generation company,especially in developing the optimal bidding strategy for maximizing revenues.Hence,it is necessary for a power generation company to develop an accurate electricity price forecasting algorithm.Given this background,this paper proposes a two-step day-ahead electricity price forecasting algorithm based on the weighted Knearest neighborhood(WKNN)method and the Gaussian process regression(GPR)approach.In the first step,several predictors,i.e.,operation indicators,are presented and the WKNN method is employed to detect the day-ahead price spike based on these indicators.In the second step,the outputs of the first step are regarded as a new predictor,and it is utilized together with the operation indicators to accurately forecast the electricity price based on the GPR approach.The proposed algorithm is verified by actual market data in Pennsylvania-New JerseyMaryland Interconnection(PJM),and comparisons between this algorithm and existing ones are also made to demonstrate the effectiveness of the proposed algorithm.Simulation results show that the proposed algorithm can attain accurate price forecasting results even with several price spikes in historical electricity price data. | Shengyuan Liu Yicheng Jiang Zhenzhi Lin Fushuan Wen Yi Ding Li Yang | 2023 | Journal of Modern Power Systems and Clean Energy2023，11，2： | 1 |
| 13 | Key Technologies of Forest Resource Examination System Development in China显示文摘1.Introduction As an important resource,forests not only provide irreplaceable economic benefits,but also yield ecological benefits that maintain the balance of terrestrial ecosystems.In addition,forests are an energy base of the biosphere.With the development of information-based technologies and globalization,accurate information regarding individual trees and standing forests in forest resource investigations is increasingly needed in order to achieve sustainable development of forestry[1–6].As an important means of obtaining information,unmanned aerial vehicles(UAVs)are becoming increasingly popular in a wide range of fields,given their developmental trends of miniaturization and diversification[7–9].Moreover,geographic information system(GIS)technology,as another type of core technology in the digital world,is undergoing rapid development. | Xiuli Zhao Zhongke Feng Yangyang Zhou Yicheng Lin | 2020 | Engineering2020，6，5： | 0 |
| 14 | Evaluation of necrosis avidity of radioiodinated 5-hydroxytryptophan and its potential applications in myocardial infarction imaging显示文摘This study aimed to seek necrosis avid agents with high safety from DNA binding agents. The interaction of 5-hydroxytryptophan(5-HTP) with DNA was investigated by a series of spectroscopic studies. Then, 5-HTP was labeled with iodine-131([^(131)I]5-HTP) and the necrosis avidity of [^(131)I]5-HTP was evaluated by in vitro cell binding assays, in vivo biodistribution experiments and blocking experiment. Finally, the potential of [^(131)I]5-HTP to image necrotic myocardium was explored in rat models with myocardial infarction by SPECT/CT imaging. Results showed that 5-HTP bound to DNA in groove binding mode and the binding constant was 1.69×10~4 L/mol. [~(^(131))I]5-HTP showed specific affinity to necrotic A549 cells,which might be related to cell nucleus. Biodistribution and autoradiography results showed preferential accumulation of [^(131)I]5-HTP in necrotic muscle(necrotic/viable muscle ratio: 6.95 ? 0.68 at 3 h postinjection(p.i.)), which could be blocked by 5-HTP with 66.7% decline, indicating that [^(131)I]5-HTP might share the same necrotic targets with 5-HTP. On SPECT/CT images, a hotspot was clearly observed at 3h p.i.in the necrotic myocardium while not in the control myocardium. In conclusion, [^(131) I]5-HTP is a novel necrosis avid agent and can rapidly visualize necrotic myocardium at 3 h p.i. The necrosis avidity mechanism of [^(131) I]5-HTP may be attributed to its interactions with exposed DNA in the necrotic tissues. | Lin Ma Lingqiao Cai Qiaomei Jin Jiajia Liang Dongjian Zhang Wei Liu Yicheng Ni Zhiqi Yin Jian Zhang Ke Pan | 2019 | Chinese Chemical Letters2019，30，1： | 0 |
| 15 | Progress,challenges,and prospects of spent lithium-ion batteries recycling:A review显示文摘The recycling and reutilization of spent lithium-ion batteries(LIBs)have become an important measure to alleviate problems like resource scarcity and environmental pollution.Although some progress has been made,battery recycling technology still faces challenges in terms of efficiency,effectiveness and environmental sustainability.This review aims to systematically review and analyze the current status of spent LIB recycling,and conduct a detailed comparison and evaluation of different recycling processes.In addition,this review introduces emerging recycling techniques,including deep eutectic solvents,molten salt roasting,and direct regeneration,with the intent of enhancing recycling efficiency and diminishing environmental repercussions.Furthermore,to increase the added value of recycled materials,this review proposes the concept of upgrading recycled materials into high value-added functional materials,such as catalysts,adsorbents,and graphene.Through life cycle assessment,the paper also explores the economic and environmental impacts of current battery recycling and highlights the importance that future recycling technologies should achieve a balance between recycling efficiency,economics and environmental benefits.Finally,this review outlines the opportunities and challenges of recycling key materials for next-generation batteries,and proposes relevant policy recommendations to promote the green and sustainable development of batteries,circular economy,and ecological civilization. | Pengwei Li Shaohua Luo Lin Zhang Qiuyue Liu Yikai Wang Yicheng Lin Can Xu Jia Guo Peam Cheali Xiaoning Xia | 2024 | Journal of Energy Chemistry2024，89，2： | 0 |
| 16 | Correction: Autophagy receptor CCDC50 modulates STING-mediated interferon response in viral infection and autoimmune disease显示文摘Correction to:Cellular&Molecular Immunology http://gffzzd3cc09b8251d45dfs0bbuc55o9w9665xb.ffgz.tsg.suse.edu.cn/10.1038/s41423-021-00758-w In the version of this article initially published,one unintended error was made during manuscript editing.The title of the article was not in accordance with that of the original manuscript,and the correct statement is“Autophagy receptor CCDC50 modulates STING-mediated interferon response in viral infection and autoimmune disease”.The results and conclusions are not affected. | Panpan Hou Yuxin Lin Zibo Li Ruiqing Lu Yicheng Wang Tian Tian Penghui Jia Xi Zhang Liu Cao Zhongwei Zhou Chunmei Li Jieruo Gu Deyin Guo | 2021 | Cellular & Molecular Immunology2021，18，12： | 0 |
| 17 | Turbidity-adaptive underwater image enhancement method using image fusion显示文摘Clear,correct imaging is a prerequisite for underwater operations.In real freshwater environment including rivers and lakes,the water bodies are usually turbid and dynamic,which brings extra troubles to quality of imaging due to color deviation and suspended particulate.Most of the existing underwater imaging methods focus on relatively clear underwater environment,it is uncertain that if those methods can work well in turbid and dynamic underwater environments.In this paper,we propose a turbidity-adaptive underwater image enhancement method.To deal with attenuation and scattering of varying degree,the turbidity is detected by the histogram of images.Based on the detection result,different image enhancement strategies are designed to deal with the problem of color deviation and blurring.The proposed method is verified by an underwater image dataset captured in real underwater environment.The result is evaluated by image metrics including structure similarity index measure,underwater color image quality evaluation metric,and speeded-up robust features.Test results exhibit that the method can correct the color deviation and improve the quality of underwater images. | Bin HAN Hao WANG Xin LUO Chengyuan LIANG Xin YANG Shuang LIU Yicheng LIN | 2022 | Frontiers of Mechanical Engineering2022，17，3： | 0 |
| 18 | Design Method of Reversely Switched Dynistor Based Pulse Circuit Without Magnetic Switch显示文摘In the reversely switched dynistor(RSD)-based pulse power circuits,a magnetic switch is usually necessary to be applied together with a main switch.It occupies space and needs a magnetic reset.In this paper,a method of designing a RSD-based pulse circuit without a magnetic switch is proposed.In the pulse circuit,a RBDT(reverse blocking diode thyristor)is used to separate the two capacitors and provide an energy branch.The pre-charge time of the RSD can be guaranteed by the energy conversion between the capacitors and inductors,instead of the saturation of the magnetic switch.In addition,the energy which is reused to trigger the RSD is based on an inductor.The pulse circuit is evaluated by simulations and practical experiments.According to the experimental results,the factors affecting the load pulse current and triggering of the RSD and RBDT are studied.Meanwhile,a method to reduce the current in the trigger switch,which is a potential problem in the pulse circuit,is proposed. | Yicheng Pi Lin Liang Xiaoxue Yan | 2023 | CSEE Journal of Power and Energy Systems2023，9，1： | 0 |
| 19 | Atomistic simulations of martensitic transformation processes for metastable FeMnCoCr high-entropy alloy显示文摘Non-equiatomic FeMnCoCr high-entropy alloy(HEA),which exhibits a great potential to break the strength-ductility trade-off relationship,has drawn abundant attention from researchers in experiments.However,atomic simulations of such excellent alloys are limited due to the lack of proper interatomic potentials.In this work,the complete martensitic transformation of nonequiatomic HEA is reproduced via atomic simulations with a novel interatomic potential under EAM framework.The physical parameters of interatomic potential agree well with experimental measurements and first-principles calculations.According to the atomic simulation results of poly-crystalline under tension and compression,two basic transition models of TRIP-DP-HEA for martensitic transformation are revealed,i.e.,the overlapping of intrinsic stacking faults or the growth of hcp laminates simultaneously.Moreover,the pathway for martensitic transformation is elucidated with the gliding of Shockley partial dislocations of 1/6<112>burgers vectors. | WANG Peng LIN YiCheng CAO Yu ZHAO HaoRan LI QianQian WANG HongTao | 2023 | Science China(Technological Sciences)2023，66，4： | 0 |
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