|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Therapeutic effects of the artemisinin analog SM934 on lupus-prone MRLIIpr mice via inhibition of TLR-triggered B-cell activation and plasma cell formation显示文摘我们以前报导了那 SM934,水溶性的 artemisinin 衍生物,是在鼠科的豺狼座模型的一个可行处理。在当前的学习,我们进一步在豺狼座容易的 MRL/lpr 老鼠上调查了 SM934 的修改剂量政体的治疗学的效果并且在 B 房间回答上探索了它的效果,在全身的豺狼座 erythematosus (SLE ) 的一个中央病原的事件。当口头上地管理了时两次每日, SM934 显著地延长了 MRL/lpr 老鼠的寿命,改善 lymphadenopathy 症状并且减少浆液的层次反原子的抗体(言论集) 并且病原的 cytokines IL-6, IL-10 和 IL-21。而且, SM934 处理由增加静止 B 房间数字在 MRL/lpr 老鼠的怒气恢复了 B 房间分隔空间,维持幼芽的中心 B 房间数字,减少激活的 B 房间数字和减少的血浆房间(PC ) 数字。前 vivo, SM934 压制了触发的像使用费的受体(TLR ) B 房间的激活和增长,以及抗体分泌物。而且,现在的学习证明 SM934 由 downregulating TLR7/9 mRNA 表示, MyD88 蛋白质表示和 NF-κ 防碍 B 房间内在的小径; B phosphorylation。在人的外部血 mononuclear 房间(PBMC ) ,与在 MRL/lpr 鼠标的结果一致, SM934 禁止了联系 TLR 的 B 房间激活和 PC 区别。在结论, SM934 的两次每日的 dosing 政体由压制 B 房间激活和血浆房间形成在豺狼座容易的 MRL/lpr 老鼠上有治疗学的效果。 | Yanwei Wu Shijun He Bingxin Bai Luyao Zhang Lu Xue Zemin Lin Xiaoqian Yang Fenghua Zhu Peilan He Wei Tang Jianping Zuo | 2016 | Cellular & Molecular Immunology2016，13，3： | 31 |
| 2 | Curve fitting and optimal interpolation on CNC machines based on quadratic B-splines显示文摘In this paper,curve fitting of 3-D points generated by G01 codes and interpolation based on quadratic B-splines are studied.Feature points of G01 codes are selected using an adaptive method.Next,quadratic B-splines are obtained as the fitting curve by interpolating these feature points.Computations required in implementing the velocity planning algorithm mentioned by Timer et al.are very complicated because of the appearance of high-order curves.An improved time-optimal method for the quadratic B-spline curves is presented to circumvent this issue.The algorithms are verified with simulations as well as on real CNC machines. | ZHANG Mei YANWei YUAN ChunMing WANG DingKang GAO XiaoShan | 2011 | Science China(Information Sciences)2011，54，7： | 21 |
| 3 | Spectral clustering based on matrix perturbation theory显示文摘This paper exposes some intrinsic characteristics of the spectral clustering method by using the tools from the matrix perturbation theory. We construct a weight ma- trix of a graph and study its eigenvalues and eigenvectors. It shows that the num- ber of clusters is equal to the number of eigenvalues that are larger than 1, and the number of points in each of the clusters can be approximated by the associated eigenvalue. It also shows that the eigenvector of the weight matrix can be used directly to perform clustering; that is, the directional angle between the two-row vectors of the matrix derived from the eigenvectors is a suitable distance measure for clustering. As a result, an unsupervised spectral clustering algorithm based on weight matrix (USCAWM) is developed. The experimental results on a number of artificial and real-world data sets show the correctness of the theoretical analysis. | TIAN Zheng LI XiaoBin JU YanWei | 2007 | Science in China(Series F)2007，50，1： | 19 |
| 4 | An investigation on tether-tugging de-orbit of defunct geostationary satellites显示文摘In recent years,defunct satellites mitigation in the geostationary orbit(GEO) has become a hot issue in the space field.How to transfer defunct geostationary satellites to the graveyard orbit safely,economically and efficiently presents new challenges to spacecraft dynamics and control.This paper conducts an in-depth investigation on tether-tugging de-orbit issues of defunct geostationary satellites.Firstly,a four-phase tether-tugging de-orbit scheme including acceleration,equilibrium,rotation and return is proposed.This scheme takes into consideration how to avoid the risks of tether ripping,tug-target collision,and tether twist,and how to achieve the mission objective of fuel saving.Secondly,the dynamics model of the tether combination system is established based on Lagrange equation,and the four phases of tether-tugging de-orbit scheme are simulated respectively.Simulation results indicate that the scheme is theoretically feasible and satisfies the design objectives of safety,economy and efficiency,providing a technical approach for engineering application. | LIU HaiTao YANG LePing ZHANG QingBin ZHU YanWei | 2012 | Science China(Technological Sciences)2012，55，7： | 18 |
| 5 | The RNA Editing Factor WSP1 Is Essentia for Chloroplast Development in Rice显示文摘尽管在 Arabidopsis thaliana 的质体编辑因素(MORF ) 的多重 organellar RNA 是位于下面 MORF 怎么在另外的种类影响植物开发的广泛地学习的、分子的细节,特别地在米饭,仍然保持大部分未知。这里,我们描述 wsp1 的描述,有白条纹的叶子和圆锥花序的米饭异种。尤其是, wsp1 在出发舞台展出了将近白的不成熟的圆锥花序。传播电子显微镜学分析和叶绿素内容测量揭示了叶绿体在 wsp1 的发展缺点和减少的叶绿素累积。在 Os04g51280 发现一个点变化的 WSP1 的位置的克隆,份额其通常认为的产品高与 MORF 蛋白质定序类似。互补实验证明 WSP1 为 wsp1 的使成杂色的显型负责。WSP1 对叶绿体局部性,在 wsp1 的点变化影响编辑多重 organellar RNA 地点。由于在编辑的质体 RNA 的缺点,叶绿体核糖体生物的续生说并且 ndhA 拼接也在 wsp1 被损害,它可以在出发阶段在叶子和圆锥花序影响正常叶绿体开发。一起,我们的结果在叶绿体开发表明米饭 WSP1 蛋白质的重要性并且在米饭关于 MORF 家庭成员拓宽我们的知识。 | Zhiguo Zhang Xuean Cui Yanwei Wang JinxiaWu Xiaofeng Gu Tiegang Lu | 2017 | Molecular Plant2017，10，1： | 15 |
| 6 | A Wheeled Wall-Climbing Robot with Bio-Inspired Spine Mechanisms显示文摘 | Yanwei Liu Shaoming Sun Xuan Wu Tao Mei | 2015 | Journal of Bionic Engineering2015，12，1： | 13 |
| 7 | Residents′Activity-travel Behavior Variation by Communities in Beijing,China显示文摘China's transition from a planned economy to a market economy has resulted in many changes in its urban structure and society and provided an opportunity for a quasi-longitudinal case study on the relationship between the built environment and activity-travel behavior.This paper draws upon data from an activity diary survey conducted in Beijing in 2007.The survey sample comprised 652 residents living in Danwei(work unit),commodity housing,and affordable housing neighborhoods.On the basis of the three-dimensional geo-visualization analysis of the space-time path and statistical multivariate regression models of daily travel and leisure time,it was found that both residential spatial factors and socio-demographics influence residents' daily behaviors.The findings show that Danwei residents have less daily travel time than those who live in commodity housing,but people living in affordable housing endure the longest travel time.Daily leisure time is associated more with individual attributes.We argue that although China's transition is currently gradual,the Danwei system may continue to play significant roles in daily life,and it might provide a valuable model for neighborhood spatial planning. | ZHAO Ying CHAI Yanwei | 2013 | Chinese Geographical Science2013，23，4： | 12 |
| 8 | Synthesis of mesoporous Cu/Mg/Fe layered double hydroxide and its adsorption performance for arsenate in aqueous solutions显示文摘The mesoporous Cu/Mg/Fe layered double hydroxide(Cu/Mg/Fe-LDH) with carbonate intercalation was synthesized and used for the removal of arsenate from aqueous solutions.The Cu/Mg/Fe-LDH was characterized by Fourier transform infrared spectrometry,X-ray diffraction crystallography,scanning electron microscopy,X-ray photoelectron spectroscopy and Brunauer-Emmett-Teller.Effects of various physico-chemical parameters such as pH,adsorbent dosage,contact time and initial arsenate concentration on the adsorption of arsenate onto Cu/Mg/Fe-LDH were investigated.Results showed that it was efficient for the removal of arsenate,and the removal efficiency of arsenate increased with the increment of the adsorbent dosage,while the arsenate adsorption capacity decreased with increase of initial pH from 3 to 11.The adsorption isotherms can be well described by the Langmuir model with R 2 > 0.99.Its adsorption kinetics followed the pseudo second-order kinetic model.Coexisting ions such as HPO42-,CO32-,SO42and NO3could compete with arsenate for adsorption sites on the Cu/Mg/Fe-LDH.The adsorption of arsenate on the adsorbent can be mainly attributed to the ion exchange process.It was found that the synthesized Cu/Mg/Fe-LDH can reduce the arsenate concentration down to a final level of < 10 μg/L under the experimental conditions,and makes it a potential material for the decontamination of arsenate polluted water. | Yanwei Guo Zhiliang Zhu Yanling Qiu Jianfu Zhao | 2013 | Journal of Environmental Sciences2013，25，5： | 11 |
| 9 | Glance Nets – efficient convolutional neural networks with adaptive hard example mining显示文摘Dear editor,Deep convolutional neural networks (CNNs) have become the dominant approach in various computer vision tasks such as image classification [1–4]. Despite the success of CNNs, it is impeded to deploy such deep CNN models in real-time tasks due to high computational complexity. To address the problem, we propose Glance Nets with several bypasses (Figure 1). In modern CNNs, it is believed that shallow layers provide lower-level features, whereas deep layers correspond to higherlevel features. However, it is not always | Hanqing SUN Yanwei PANG | 2018 | Science China(Information Sciences)2018，61，10： | 11 |
| 10 | Lumbar spine superior-level facet joint violations: percutaneous versus open pedicle screw insertion using intraoperative 3-dimensional computer-assisted navigation显示文摘 | Tian Wei Xu Yunfeng Liu Bo Liu Yajun He Da Yuan Qiang Lang Zhao Lyu Yanwei Han Xiaoguang Jin Peihao | 2014 | Chinese Medical Journal2014，，22： | 10 |
| 11 | Deformation control of asymmetric floor heave in a deep rock roadway:A case study显示文摘In order to control asymmetric floor heave in deep rock roadways and deformation around the surrounding rock mass after excavation, in this paper we discuss the failure mechanism and coupling control countermeasures using the finite difference method(FLAC3D) combined with comparative analysis and typical engineering application at Xingcun coal mine. It is indicated by the analysis that the simple symmetric support systems used in the past led to destruction of the deep rock roadway from the key zone and resulted in the deformation of asymmetric floor heave in the roadway. Suitable reinforced support countermeasures are proposed to reduce the deformation of the floor heave and the potential risk during mining. The application shows that the present support technology can be used to better environmental conditions. The countermeasures of asymmetric coupling support can not only effectively reduce the discrepancy deformation at the key area of the surrounding rock mass, but also effectively control floor heave, which helps realize the integration of support and maintain the stability of the deep rock roadways at Xingcun coal mine. | Sun Xiaoming Wang Dong Feng Jili Zhang Chun Chen Yanwei | 2014 | International Journal of Mining Science and Technology2014，24，6： | 10 |
| 12 | Coastal seafloor observatory at Xiaoqushan in the East China Sea显示文摘The seafloor observation system is becoming an important infrastructure for marine research because it is transforming oceanic research from temporal investigation to long term observation.The East China Sea coastal seafloor observatory,located between 30°31′44″N,122°15′12″E and 30°31′34″N,122°14′40″E,is constructed near the Xiaoqushan Island outside the Hangzhou Bay on the inner continental shelf of the East China Sea.The observatory is connected by a submarine optical fiber composite power cable that is more than one kilometer long and consists of a special junction box that transmits power and communication signals to different instruments.The special junction box has a variety of waterproof plugs and connects to three different instruments installed in a trawl preventer.The submarine optical fiber composite power cable is landed on the platform by The East China Sea Branch,State Oceanic Administration and the power is continuously supplied by the solar panels and solar battery on the top of the platform.The real time data are directly sent through the cable to the platform and are transmitted by CDMA wireless to the receiver at the State Key Laboratory of Marine Geology of Tongji University.Measurements at the observatory have been taken since April 20,2009 after installation and the results have been interpreted.The characteristics of the near bottom boundary are constrained by a sediment suspension model using portion of the observed data.In particular,discussion is provided on the sea surface height anomaly at Xiaoqushan Island influenced by the tsunami driven by the 2010 Earthquake in Chile.The successful establishment of the coastal seafloor observatory is the first step toward future development of seafloor observation systems in China.It not only accumulates experiences in technology and engineering,but also paves the way for performing important oceanic research using the long term continuous observation platform. | XU HuiPing ZHANG YanWei XU ChangWei LI JianRu LIU Ding QIN RuFu LUO ShenQian FAN DaiDu | 2011 | Chinese Science Bulletin2011，56，26： | 10 |
| 13 | Application of high magnetic fields in advanced materials processing显示文摘Recently,steady magnetic fields avail-able from cryogen-free superconducting magnets open up new ways to process materials. In this paper,the main results obtained by using a high magnetic field to process several advanced materials are re-viewed. These processed objects primarily include superconducting,magnetic,metallic and nanome-ter-scaled materials. It has been found that a high magnetic field can effectively align grains when fab-ricating the magnetic and non-magnetic materials and make inclusions migrate in a molten metal. The mechanism is discussed from the theoretical view-point of magnetization energy. | MA Yanwei XIAO Liye YAN Luguang | 2006 | Chinese Science Bulletin2006，51，24： | 9 |
| 14 | Streamflow responses to climate change and LUCC in a semi-arid watershed of Chinese Loess Plateau显示文摘Climate change and Land Use/Cover Change(LUCC) have been identified as two primary factors affecting watershed hydrological regime. This study analyzed the trends of streamflow, precipitation, air temperature and potential evapotranspiration(PET) from 1962 to 2008 in the Jihe watershed in northwestern Loess Plateau of China using the Mann-Kendall test. The streamflow responses to climate change and LUCC were quantified independently by the elasticity method. The results show that the streamflow presented a dramatic decline with a turning point occurred in 1971, while the precipitation and PET did not change significantly. The results also show that the temperature rose markedly especially since 1990 s with an approximate increase of 1.74°C over the entire research period(1962–2008). Using land use transition matrix, we found that slope cropland was significantly converted to terrace between 1970 s and 1990 s and that forest cover increased relatively significantly because of the Grain for Green Project after 2000. The streamflow reduction was predominantly caused by LUCC and its contribution reached up to 90.2%, while the contribution of climate change to streamflow decline was only 9.8%. Although the analytical results between the elasticity method and linear regression model were not satisfactorily consistent, they both indicated that LUCC(human activity) was the major factor causing streamflow decline in the Jihe watershed from 1962 to 2008. | LI Qingyun SUN Yanwei YUAN Wenlin LYU Subing WAN Fang | 2017 | Journal of Arid Land2017，9，4： | 9 |
| 15 | New Hybrid Parallel Algorithm for Variable-sized Batch Splitting Scheduling with Alternative Machines in Job Shops显示文摘The batch splitting scheduling problem has recently become a major target in manufacturing systems, and the researchers have obtained great achievements, whereas most of existing related researches focus on equal-sized and consistent-sized batch splitting scheduling problem, and solve the problem by fixing the number of sub-batches, or the sub-batch sizes, or both. Under such circumstance and to provide a practical method for production scheduling in batch production mode, a study was made on the batch splitting scheduling problem on alternative machines, based on the objective to minimize the makespan. A scheduling approach was presented to address the variable-sized batch splitting scheduling problem in job shops trying to optimize both the number of sub-bathes and the sub-batch sizes, based on differential evolution(DE), making full use of the finding that the sum of values of genes in one chromosome remains the same before and after mutation in DE. Considering before-arrival set-up time and processing time separately, a variable-sized batch splitting scheduling model was established and a new hybrid algorithm was brought forward to solve both the batch splitting problem and the batch scheduling problem. A new parallel chromosome representation was adopted, and the batch scheduling chromosome and the batch splitting chromosome were treated separately during the global search procedure, based on self-adaptive DE and genetic crossover operator, respectively. A new local search method was further designed to gain a better performance. A solution consists of the optimum number of sub-bathes for each operation per job, the optimum batch size for each sub-batch and the optimum sequence of sub-batches. Computational experiments of four test instances and a realistic problem in a speaker workshop were performed to testify the effectiveness of the proposed scheduling method. The study takes advantage of DE's distinctive feature, and employs the algorithm as a solution approach, and thereby deepens and enriches the content of batch splitting scheduling. | ZHAO Yanwei WANG Haiyan WANG Wanliang XU Xinli | 2010 | Chinese Journal of Mechanical Engineering2010，23，4： | 8 |
| 16 | Constitutive model for methane desorption and diffusion based on pore structure differences between soft and hard coal显示文摘This paper aims to improve the accuracy and applicability of gas diffusion mathematical models from coal particles. Firstly, a new constitutive model for gas diffusion from coal particles with tri-disperse pore structure is constructed by considering the difference in characteristics between soft coal and hard coal.The analytical solution is then derived, that is, the quantitative relationship between gas diffusion rate(Qt/Q_∞) and diffusion time(t), The pore structure parameters of soft coal and hard coal from Juji coal mine are determined. Gas diffusion rules are numerically calculated and investigated by physical simulation methods. Lastly, the applicability of this model is verified. The results show that the homogeneous model only applies to the gas diffusion process of hard coal during the initial 10 min. The calculation results from this model and the physical experimental results of soft coal and hard coal are nearly identical during the initial 30 min. | Liu Yanwei Wang Dandan Hao Fuchang Liu Mingju Mitri Hani S. | 2017 | International Journal of Mining Science and Technology2017，27，6： | 8 |
| 17 | Sedimentation processes and sedimentary characteristics of tidal bores along the north bank of the Qiantang Estuary显示文摘A tidal bore is a unique Earth surface process, characterized by its highly destructive energy, predictable periodicities and magni-tudes, and the production of characteristic sedimentary features. Tidal bores and associated rapid flood flows are highly turbulent flows of the upper-flow regime with a velocity over several meters per second. Reynolds (Re) and Froude (Fr) numbers, respectively, are larger than 104 and 1.0, making them significantly different from regular tidal flows but analogous to turbidity currents. Until now, understanding of tidal-bore depositional processes and products has been limited because of the difficulty and hazards involved with gauging tidal bores directly. The Qiantang bore is known as the largest breaking bore in the world. Field surveys were carried out in May 2010, along the north bank of the Qiantang Estuary to observe the occurrence of peak bores, including regular observations of current, water level and turbidity at the main channel. Several short cores were sampled on the intertidal flats to study the characteristic sedimentary features of tidal bores. Hydrodynamic and sedimentological studies show that the processes of sediment resuspension, transport and deposition are controlled primarily by the tidal bores, and the subsequent abruptly accelerated and decelerated flood flows, which only account for one tenth of each semidiurnal tidal cycle in the estuary. Tidal-bore deposits are generally poorly sorted because of rapid sedimentation after highly mixed suspension by intense turbulence. This behavior is characteristic of the absence of tractive-current depositional components in a C-M diagram. It also goes along with well-developed massive bedding, graded bedding, basal erosion structures, convolute bedding and dewatering structures. Together, these sedimentary features can constitute fingerprinting of turbidites, widely distributed in the deep-water environment. However, a tidal bore is triggered by intensely deformed tidal waves propagating into a shallow-water environment, which returns to regular tidal flows rapidly after the passage of the bore head. The tidal-bore deposits are usually bounded by the intertidal-flat deposits with typical tidal beddings at the top and on both flanks. The difference between tidal-bore deposits (TBD) and tidal sandy/muddy deposits (TSD/TMD) is evident not only in sedimentary structures, but also in the grain-size composition. They can be clearly distinguished in grain-size bivariate plots, typically the plot of mean grain size vs. standard deviation (or sorting). Some trend variations generally exist in mean grain size with TBD>TSD>TMD, sorting with TMD>TBD>TSD (larger value indicating poorer sorting), and both skewness and kurtosis with TSD>TBD>TMD. These findings will undoubtedly shed new light on our understanding of tidal-bore sedimentology, ancient tidal-bore sedimentary facies and environments, and related oil-and-gas field prospecting. | FAN DaiDux CAI GuoFu SHANG Shuai WU YiJing ZHANG YanWei GAO Lei | 2012 | Chinese Science Bulletin2012，57，13： | 8 |
| 18 | Energy storage through intercalation reactions:electrodes for rechargeable batteries显示文摘Electrochemical energy storage has been an important enabling technology for modern electronics of all kinds,and will grow in importance as more electric vehicles and grid-scale storage systems are deployed.We briely review the history of intercalation electrodes and basic concepts pertaining to bateries based on intercalation reactions.hen we summarize how the critical performance metrics—energy density,power density,safety and stability—relate back to electrode materials properties,and how these materials properties are related to fundamental chemical and physical structure relationships highlighted with the most recent research advancement.Challenges and avenues for further research have been highlighted throughout. | Robert C.Massé Chaofeng Liu Yanwei Li Liqiang Mai Guozhong Cao | 2017 | National Science Review2017，4，1： | 8 |
| 19 | Novel Recombinant Seneca Valley Virus Isolated from Slaughtered Pigs in Guangdong Province显示文摘Dear Editor,Since the first outbreak in Brazil in 2015,Seneca Valley virus(SVV)associated with porcine idiopathic vesicular disease,has shown increasing geographic distribution.Cases of SVV have been reported from several countries including the United States(US),Colombia,Thailand,Canada,and China(Pasma et al.2008;Zhang et al.2015;Sun et al.2017;Wu et al.2017;Liu et al.2018;Saeng-Chuto et al.2018).SVV was first identified in the US in 2002 and is the only member of the genus Senecavirus in the family Picomaviridae(Hales et al.2008;Leme et al.2017).The SVV genome contains a large open reading frame(ORF)encoding a polyprotein,which is cleaved into various mature viral proteins including the leader protein(L),structural proteins(VP1,VP2,VP3,and VP4),and non-structural proteins(2A,2B,2C,3A,3B,3C,and 3D)(Hales et al 2008).Structural proteins bind to their receptor,anthrax toxin receptor 1,to mediate viral invasion and stimulate specific immunity of the host(Jayawardena et al.2018).Non-structural proteins such as 3C suppress innate immune responses by degrading interferon regulatory factor 3(IRF 3)and IRF7 and inhibit the activation of RIG-1,TBK1,and TRAF3 through deubiquitination(Xue et al 2018). | Jianxin Liu Yunfeng Zha Huizi Li Yanwei Sun Fuguang Wang Rong Lu Zhangyong Ning | 2019 | Virologica Sinica2019，34，6： | 7 |
| 20 | A method for estimating the contribution of evaporative vapor from Nam Co to local atmospheric vapor based on stable isotopes of water bodies显示文摘During the summer monsoon season,the moisture of precipitation events in southern and central regions of the Tibetan Plateau is mainly moisture from the Indian Ocean transported by the Indian monsoon and terrestrial vapor derived from the surface of the Tibetan Plateau.However,the respective contributions of these two types of moisture are not clear.From June to September,the excess deuterium values of precipitation and river water in the Nam Co basin are higher than those for the southern Tibetan Plateau.This reflects the mixing of evaporation from Nam Co and local atmospheric vapor.On the basis of theory for estimating the contribution of evaporative vapor from surface water bodies to atmospheric vapor and relative stable isotopes in water bodies (precipitation,river water,atmospheric moisture and lake water),this study preliminarily estimates that the average contribution of evaporation from the Lake Nam Co to local atmospheric vapor has varied from 28.4% to 31.1% during the summer monsoon season in recent years. | XU YanWei KANG ShiChang ZHANG YuLan ZHANG YongJun | 2011 | Chinese Science Bulletin2011，56，14： | 7 |
您所在的机构暂未开通此部分的功能，请联系管理员