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| 1 | The Seismogenic Structure of the 2010 Suining Ms 5.0 Earthquake and its Geometry,Kinematics and Dynamics Analysis显示文摘在 2010 年 1 月, Suining Ms5.0 地震发生在中央四川盆,与在 Moxi-Longnvsi 结构的带和 10 km 的焦点的深度的震中。在这个区域基于地震侧面的结构的解释,我们认出了在 910 km 的深度位于 Suining 区域的 Presinian 地下室的一个地区性的分开差错,转移它从 NW 滑倒到 SE 取向。从 NW 滑动到 SE,并且经历了几的这个分开差错砍并且弯曲,它引起了地下室被卷在并且覆盖阶层褶层变丑。它在 Moxi 区域形成了差错拐弯褶层与一近似 4 km 滑倒。相应地, Moxi 背斜的形成与分开差错有关。与地震分开差错的斜面上的震中,有一个新观点, Suining 地震被这个地下室分开差错的复活引起。自从迟了的侏罗记时期,在地区性的构造应力的影响下面,分开差错从 Longmen 山( LMS )戳带把它的slip 转移了到四川盆的内地,并且最后到西南 Huayingshan ( HYS )的山麓地区,它显示 HYS 可能是 LMS 戳带的最后的前面区域。 | LU Renqi HE Dengfa JOHN Suppe MA Yongsheng GUAN Shuwei SUN Yanpeng GAO Jinwei | 2011 | Acta Geologica Sinica(English Edition)2011,85,6: | 5 |
| 2 | Coupling control on pillar stress concentration and surface cracks in shallow multi-seam mining显示文摘In order to ensure safe mining and reduce surface damage in shallow multi-seam mining,the failure characteristics of interburden strata with different coal pillars offset distances between pillars in the upper and lower seams,the distribution characteristics of stress concentration in coal pillars,and the development characteristics of stratum cracks and subsidence were investigated by physical and UDEC2D simulation.Meanwhile,the effect of different coal pillar offset distances on stress concentration of coal pillar and development of stratum cracks were studied.Based on those results,a formula for safe mining and reducing surface damage was established,which provided a theoretical basis for safe and environmentally friendly mining in shallow multi-seam.According to the results,the optimal coal pillar offset distance(the side to side horizontal distance of the upper and lower coal pillars)between the upper and lower coal seams was developed to reduce the stress concentration of coal pillars and surface damage.The results of this study have been applied in Ningtiaota coal mine and have achieved good results in safe and environmentally friendly mining. | Qingxiang Huang Junwu Du Jie Chen Yanpeng He | 2021 | International Journal of Mining Science and Technology2021,31,1: | 4 |
| 3 | Mesoporous PtPd nanoparticles for ligand-mediated and imaging-guided chemo-photothermal therapy of breast cancer显示文摘The synergistic therapy of chemotherapy and photothermal therapy(PTT)has been reported as a promising antitumor strategy.To achieve effective combination therapy,developing more suitable candidate nanomaterials with optimal photothermal property and high chemical drug loading capacity is very necessary.Herein,a bimetallic PtPd nanoparticle was synthesized with the merits of excellent photothermal effect and mesoporous structure for doxorubicin(DOX)loading.We further designed PtPd-ethylene glycol(PEG)-folic acid(FA)-doxorubicin(DOX)nanoparticle for chemo-photothermal therapy of MCF-7 tumor with folic acid engineering to achieve active targeting.Moreover,excellent photoacoustic(PA)imaging of PtPd-PEG-FA-DOX nanoparticles facilitated the precise in vivo tracking and further evaluation of nanoparticles’targeting effect.The in vitro and in vivo results both demonstrated PtPd-PEG-FA-DOX nanoparticles serve as a safe and promising system for effective treatment of MCF-7 tumor. | Yanpeng Jia Yang Song Ying Qu Jinrong Peng Kun Shi Dan Du He Li Yuehe Lin Zhiyong Qian | 2020 | Nano Research2020,13,6: | 2 |
| 4 | Camptothecin@HMSNs/thermosensitive hydrogel composite for applications in preventing local breast cancer recurrence显示文摘Camptothecin has a strong tumor killing ability for a variety of tumor cells with its special anti-cancer mechanism including the breast cancer. However, because of its infinite hydrophobic property, its clinical application has been greatly limited. Early prevention of loco regional recurrence for the breast cancer is critical for patients who have undergone breast-conserving therapy. In the study,CPT was used for the inhibition of the recurrence after the operation. The hollow mesoporous silica nanoparticles were used as the carrier to improve the hydrophilic property and increase its bioavailability with the high loading capacity. The ability of the cellular uptake and antitumor activity was increased. Hydrogel was the ideal carrier for local therapy, so the CPT@HMSNs were loaded into the PLEL thermo sensitive hydrogel to be injected into the tumor sites after the tumor was resected. The recurrence was reduced in the group of CPT-HMSNs-PLEL and the side effect of CPT was decreased. They exhibit distinguished potential as drug carrier for local delivery. | Jing Wu Ying Qu Kun Shi Bingyang Chu Yanpeng Jia Xue Xiao Qianjun He Zhiyong Qian | 2018 | Chinese Chemical Letters2018,29,12: | 2 |
| 5 | Mass Transfer, Gas Holdup, and Kinetic Models of Batch and Continuous Fermentation in a Novel Rectangular Dynamic Membrane Airlift Bioreactor显示文摘Compared with conventional cylinder airlift bioreactors(CCABs)that produce coarse bubbles,a novel rectangular dynamic membrane airlift bioreactor(RDMAB)developed in our lab produces fine bubbles to enhance the volumetric oxygen mass transfer coefficient(k_(L)a)and gas holdup,as well as improve the bioprocess in a bioreactor.In this study,we compared mass transfer,gas holdup,and batch and con-tinuous fermentation for RNA production in CCAB and RDMAB.In addition,unstructured kinetic models for microbial growth,substrate utilization,and RNA formation were established.In batch fermentation,biomass,RNA yield,and substrate utilization in the RDMAB were higher than those in the CCAB,which indicates that dynamic membrane aeration produced a high k_(L)a by fine bubbles;a higher k_(L)a is more bene-ficial to aerobic fermentation.The starting time of continuous fermentation in the RDMAB was 20 h ear-lier than that in the CCAB,which greatly improved the biological process.During continuous fermentation,maintaining the same dissolved oxygen level and a constant dilution rate,the biomass accumulation and RNA concentration in the RDMAB were 9.71% and 11.15% higher than those in the CCAB,respectively.Finally,the dilution rate of RDMAB was 16.7% higher than that of CCAB during con-tinuous fermentation while maintaining the same air aeration.In summary,RDMAB is more suitable for continuous fermentation processes.Developing new aeration and structural geometry in airlift bioreac-tors to enhance k_(L)a and gas holdup is becoming increasingly important to improve bioprocesses in a bioreactor. | Ganlu Li Kequan Chen Yanpeng Wei Jinlei Zeng Yue Yang Feng He Hui Li Pingkai Ouyang | 2022 | Engineering2022,8,6: | 1 |
| 6 | Effective suppression of mode distortion induced by amplifiers stimulated Raman scattering in high-power fiber显示文摘Mode distortion induced by stimulated Raman scattering(SRS)has become a new obstacle for the further development of high-power fiber lasers with high beam quality.Here,an approach for effective suppression of the SRS-induced mode distortion in high-power fiber amplifiers has been demonstrated experimentally by adjusting the seed power(output power of seed source)and forward feedback coefficient of the rear port in the seed source.It is shown that the threshold power of the SRS-induced mode distortion can be increased significantly by reducing the seed power or the forward feedback coefficient.Moreover,it has also been found that the threshold power is extremely sensitive to the forward feedback power value from the rear port.The influence of the seed power on the threshold power can be attributed to the fact that the seed power plays an important role in the effective length of the gain fiber in the amplifier.The influence of the forward feedback coefficient on the threshold power can be attributed to the enhanced SRS configuration because the end surface of the rear port together with the fiber in the amplifier constitutes a half-opening cavity.This suppression approach will be very helpful to further develop the high-power fiber amplifiers with high beam quality. | Wei Gao Wenhui Fan Pei Ju Gang Li Yanpeng Zhang Aifeng He Qi Gao Zhe Li | 2021 | High Power Laser Science and Engineering2021,9,2: | 1 |
| 7 | SCFβ-TRCP E3 ubiquitin ligase targets the tumor suppressor ZNRF3 for ubiquitination and degradation显示文摘 | Yanpeng Ci Xiaoning Li Maorong Chen Jiateng Zhong Brian J. North Hiroyuki Inuzuka Xi He Yu Li Jianping Guo Xiangpeng Dai | 2018 | Protein & Cell2018,9,10: | 1 |
| 8 | Stimulus-responsive water soluble synthetic nanographene显示文摘Nanographenes(NGs)are exceptionally hydrophobic.They are insoluble in water,preventing the exploration and utilization of their photophysical properties under aqueous conditions.This work discloses an atomically precise water-soluble synthetic NG1,featuring a 2 nm sp^(2) carbon skeleton appended with 12 branched triethylene glycol chains.It synergistically combines low critical solution temperature(LCST)behavior and a photothermal effect to create the first thermo-and photo-responsive atomically precise NG functioning in an aqueous solution.The LCST behavior can be attributed to a delicate balance of hydrophobic-hydrophilic interactions,providing a sensitive thermal response to changes over a temperature range of physiological interest(close to 37℃).Moreover,1 has considerable photothermal conversion capability,with irradiation of 1 in water by red or near infrared light increasing the solutions temperature to above the clouding point within seconds,leading to a reversible clear-to-turbid transition over many cycles without evident fatigue. | Shuang Ma Yanpeng Zhu Weitao Dou Ying Chen Xiaopeng He Jiaobing Wang | 2021 | Science China Chemistry2021,64,4: | 0 |
| 9 | Seamlessly Merging the Capacity of P into Sb at Same Voltage with Maintained Superior Cycle Stability and Low-temperature Performance for Li-ion Batteries显示文摘Among the alloying-type anodes,elemental Sb possesses the suitable yet safe plateau,simple lithiation pathway,small voltage polarization,high conductivity,and superior cycle stability.However,challenge is that its intrinsic capacity is rather low(660 mAh g^(-1)),<1/6 of silicon.Herein,we propose a seamless integration strategy by merging the voltage and capacity of phosphorus and antimony into a solid solution alloy.Interestingly,the enlistment of P is found greatly enlarge the capacity from 660 to 993 mAh g^(-1) for such Sb_(30)P_(30) solid solution,while maintaining a single and stable discharge plateau(~0.79 V)similar to elemental Sb.Various experimental characterizations including XPS,PDF,Raman,and EDS mapping reveal that in such a material the P and Sb atoms have interacted with each other to form a homogenous solid solution alloy,rather than a simple mixing of the two substances.Thus,the Sb_(30)P_(30) exhibits superior rate performances(807 mAh g^(-1) at 5000 mA g^(-1))and cyclability(821 mAh g^(-1) remained after 300 cycles).Furthermore,such Sb_(60-x)P_(x) alloys can even deliver 621 mAh g^(-1) at30℃,which can be served as the alternative anode materials for high-energy and low-temperature batteries.This unique seamless integration strategy based on solid solution chemistry can be easily leveraged to manipulate the capacity of other electrode materials at similar voltage. | Yaqing Wei Jun He Jie Zhang Mingyang Ou Yanpeng Guo Jiajun Chen Cheng Zeng Jia Xu Jiantao Han Tianyou Zhai Huiqiao Li | 2023 | Energy & Environmental Materials2023,6,2: | 0 |
| 10 | Bioinspired Multifunctional Self-Sensing Actuated Gradient Hydrogel for Soft-Hard Robot Remote Interaction显示文摘The development of bioinspired gradient hydrogels with self-sensing actuated capabilities for remote interaction with soft-hard robots remains a challenging endeavor. Here, we propose a novel multifunctional self-sensing actuated gradient hydrogel that combines ultrafast actuation and high sensitivity for remote interaction with robotic hand. The gradient network structure, achieved through a wettability difference method involving the rapid precipitation of MoO_(2) nanosheets, introduces hydrophilic disparities between two sides within hydrogel. This distinctive approach bestows the hydrogel with ultrafast thermo-responsive actuation(21° s^(-1)) and enhanced photothermal efficiency(increase by 3.7 ℃ s^(-1) under 808 nm near-infrared). Moreover, the local cross-linking of sodium alginate with Ca^(2+) endows the hydrogel with programmable deformability and information display capabilities. Additionally, the hydrogel exhibits high sensitivity(gauge factor 3.94 within a wide strain range of 600%), fast response times(140 ms) and good cycling stability. Leveraging these exceptional properties, we incorporate the hydrogel into various soft actuators, including soft gripper, artificial iris, and bioinspired jellyfish, as well as wearable electronics capable of precise human motion and physiological signal detection. Furthermore, through the synergistic combination of remarkable actuation and sensitivity, we realize a self-sensing touch bioinspired tongue. Notably, by employing quantitative analysis of actuation-sensing, we realize remote interaction between soft-hard robot via the Internet of Things. The multifunctional self-sensing actuated gradient hydrogel presented in this study provides a new insight for advanced somatosensory materials, self-feedback intelligent soft robots and human–machine interactions. | He Liu Haoxiang Chu Hailiang Yuan Deliang Li Weisi Deng Zhiwei Fu Ruonan Liu Yiying Liu Yixuan Han Yanpeng Wang Yue Zhao Xiaoyu Cui Ye Tian | 2024 | Nano-Micro Letters2024,16,4: | 0 |