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| 1 | H7N9 virulent mutants detected in chickens in China pose an increased threat to humans显示文摘 | Jianzhong Shi Guohua Deng Huihui Kong Chunyang Gu Shujie Ma Xin Yin Xianying Zeng Pengfei Cui Yan Chen Huanliang Yang Xiaopeng Wan Xiurong Wang Liling Liu Pucheng Chen Yongping Jiang Jinxiong Liu Yuntao Guan Yasuo Suzuki Mei Li Zhiyuan Qu Lizheng Guan Jinkai Zang Wenli Gu Shuyu Han Yangming Song Yuzhen Hu Zeng Wang Linlin Gu Wenyu Yang Libin Liang Hongmei Bao Guobin Tian Yanbing Li Chuanling Qiao Li Jiang Chengjun Li Zhigao Bu Hualan Chen | 2017 | Cell Research2017，27，12： | 70 |
| 2 | Source Rocks for the Giant Puguang Gas Field,Sichuan Basin:Implication for Petroleum Exploration in Marine Sequences in South China显示文摘摘要:详细地球化学研究被进行在巨大的 Puguang 煤气的领域里调查稳固的沥青和烃气体的起源。稳固的沥青的二种类型被认出:低硫在在 Xujiahe 形成和高硫的沙岩水库的沥青满足的满意的、低反射(LSLR ) 固体,高反射(HSHR ) 固体在在更低的三叠纪的 Feixianguan 和上面的二叠的 Changxing 形成的碳酸盐水库的沥青。在上面的三叠纪的 Xujiahe 形成的稳固的沥青与摘录相关很好从上面对在同位素的作文的侏罗记 nonmarine 来源岩石三叠纪浸透并且芳香的部分和 biomarker 分发。在 Feixianguan 和 Changxing 形成的稳固的沥青与摘录从显然不同寒武纪并且志留纪岩石但是在同位素的作文两个都从上面的二叠的来源岩石与摘录显示合理关联浸透并且芳香的部分并且在 biomarker 分发,建议二叠特别上面的二叠的 Longtan 形成是在在在 th 的 Feixianguan 和 Changxing 形成的碳酸盐水库的稳固的沥青的主要来源天然气的化学、同位素的作文显示烃气体的多数从生存于富有腐殖质的有机物发源并且是积累的油的热裂开的产品。这研究显示生存于富有腐殖质的有机物统治的那来源岩石存在在上面二叠并且做了主要贡献到巨大的 Puguang 煤气的地,它在华南在海洋的序列为石油探索有重要牵连。 | ZOU Huayao HAO Fang ZHU Yangming GUO Tonglou CAI Xunyu LI Pingping ZHANG Xuefeng | 2008 | Acta Geologica Sinica(English Edition)2008，82，3： | 11 |
| 3 | New innovations in pavement materials and engineering:A review on pavement engineering research 2021显示文摘Sustainable and resilient pavement infrastructure is critical for current economic and environmental challenges.In the past 10 years,the pavement infrastructure strongly supports the rapid development of the global social economy.New theories,new methods,new technologies and new materials related to pavement engineering are emerging.Deterioration of pavement infrastructure is a typical multi-physics problem.Because of actual coupled behaviors of traffic and environmental conditions,predictions of pavement service life become more and more complicated and require a deep knowledge of pavement material analysis.In order to summarize the current and determine the future research of pavement engineering,Journal of Traffic and Transportation Engineering(English Edition)has launched a review paper on the topic of'New innovations in pavement materials and engineering:A review on pavement engineering research 2021'.Based on the joint-effort of 43 scholars from 24 well-known universities in highway engineering,this review paper systematically analyzes the research status and future development direction of 5 major fields of pavement engineering in the world.The content includes asphalt binder performance and modeling,mixture performance and modeling of pavement materials,multi-scale mechanics,green and sustainable pavement,and intelligent pavement.Overall,this review paper is able to provide references and insights for researchers and engineers in the field of pavement engineering. | JTTE Editorial Office Jiaqi Chen Hancheng Dan Yongjie Ding Yangming Gao Meng Guo Shuaicheng Guo Bingye Han Bin Hong Yue Hou Chichun Hu Jing Hu Ju Huyan Jiwang Jiang Wei Jiang Cheng Li Pengfei Liu Yu Liu Zhuangzhuang Liu Guoyang Lu Jian Ouyang Xin Qu Dongya Ren Chao Wang Chaohui Wang Dawei Wang Di Wang Hainian Wang Haopeng Wang Yue Xiao Chao Xing Huining Xu Yu Yan Xu Yang Lingyun You Zhanping You Bin Yu Huayang Yu Huanan Yu Henglong Zhang Jizhe Zhang Changhong Zhou Changjun Zhou Xingyi Zhu | 2021 | Journal of Traffic and Transportation Engineering(English Edition)2021，8，6： | 7 |
| 4 | Large Noncoding RNAs Are Promising Regulators in Embryonic Stem Cells显示文摘Embryonic stem cells(ESCs) hold great promises for treating and studying numerous devastating diseases. The molecular basis of their potential is not completely understood. Large noncoding RNAs(lnc RNAs) are an important class of gene regulators that play essential roles in a variety of physiologic and pathologic processes. Dozens of lnc RNAs are now identified to control ESC self-renewal and differentiation. Research on lnc RNAs may provide novel insights into manipulating the cell fate or reprogramming somatic cells into induced pluripotent stem cells(i PSCs). In this review, we summarize the recent research efforts in identifying functional lnc RNAs and understanding how they act in ESCs, and discuss various future directions of this field. | Ya-Pu Li Yangming Wang | 2015 | Journal of Genetics and Genomics2015，42，3： | 5 |
| 5 | Thermal evolution and applications of aromatic hydrocarbons in highly mature coal-bearing source rocks of the Upper Triassic Xujiahe Formation in the northern Sichuan Basin显示文摘Based on the GC-MS analytical data of aromatic fractions of over forty highly mature coal-bearing source rock samples collected from the Upper Triassic Xujiahe Formation in the northern Sichuan Basin, the thermal evolution of aromatic hydrocarbons during late-mature to over-mature stage(Ro=1.13%–2.85%) was characterized, and aromatic indicators suitable for recognizing the organic source and sedimentary environment of high maturity source rocks were discussed. The results indicated that the concentrations of low carbon-cycle naphthalene as well phenanthrene series reduce gradually with increasing Ro at the highly mature levels. However, some high-cyclic components such as chrysene, benzofluoranthene, and benzo[e]pyrene are relatively enriched, in companying an enhancement of parent aromatic compounds. The variations are attributed to thermal cracking and polymerization reactions due to continuous dehydrogenation under enhanced burial temperature. As thermal maturity rises, MPI1(Methylphenanthrene Index) values display a two-modal varying trend, namely, increasing when Ro is below 1.80% and decreasing above 1.8% Ro. The relationships between Ro and MPI1 are Ro=0.98MPI1+0.37 for Ro<1.80% and Ro=?0.90MPI1+3.02 at Ro>1.8%, being different from the previous research. The amount of dibenzofurans declines sharply at Ro higher than 1.1%, leading to a significant change of relative composition among dibenzothiophenes, dibenzofurans and fluorenes(referred as three-fluorenes series composition). Thus, this parameter appears to be unsuitable for identifying the sedimentary environment of the highly matured source rocks. 4-/1-MDBT(methyldibenzothiophene) ratio could be served as an effective indicator for organic facies, and can distinguish coals from mudstones at over-maturity in this case. The ratios of 2,6-/2,10-DMP(dimethylphenanthrene) and 1,7-/1,9-DMP and relative abundance of triaromatic steroids in these highly mature rocks could be considered as biological source parameters for relative input of terrigenous versus aquatic organic matter. | LI Ying ZHU YangMing HAO Fang ZOU HuaYao GUO TongLou | 2015 | Science China Earth Sciences2015，58，11： | 4 |
| 6 | Accumulation Mechanisms and Evolution History of the Giant Puguang Gas Field,Sichuan Basin,China显示文摘稳固的沥青在 Puguang 煤气的地里在整个碳酸盐水库被发现,最大的煤气的地到目前为止在中国在海洋的碳酸盐发现了,证实 Puguang 煤气的地从一座 paleo 油水库演变。液体水管系统在这域里的集中的油累积的时候被重建,并且石油移植小径用一个 3-D 模型被建模并且由 geochemical 参数跟踪了。向前建模并且倒置跟踪与对方一起与一致,两个显示油在 Puguang-Dongyuezhai 结构积累了从一个生产厨房发源到 Puguang 气体地的西北。生存于富有腐殖质的有机物在东北四川盆,是垂直地近来源的岩石和旁边地在生产附近的厨房的液体水管系统的发展,并且集中油统治的器官富人的上面的二叠的来源岩石的免职从生产厨房的一个大区域发源,是为巨大的 Puguang 煤气的地从演变的巨大的paleo油水库的形成的三个要求。Puguang 煤气的地经历了三阶段的进化。累积以后的进程,特别在 hydrocarbon-water-rock 系统的器官无机的相互作用,深刻地不仅改变了石油液体的作文和特征,而且显然在水库改变了物理化学的条件并且导致了碳酸盐矿物质的复杂降水和答案。 | HAO Fang GUO Tonglou DU Chunguo ZOU Huayao CAI Xunyu ZHU Yangming LI Pingping WANG Chunwu ZHANG Yuanchun | 2009 | Acta Geologica Sinica(English Edition)2009，83，1： | 4 |
| 7 | Fabrication of poly(vinylidene fluoride) membrane via thermally induced phase separation using ionic liquid as green diluent显示文摘Ionic liquid(IL),1-butyl-3-methylimidazolium hexafluorophosphate([BMIM]PF6)as a new and environmentally friendly diluent was introduced to prepare poly(vinylidene fluoride)(PVDF)membranes via thermally induced phase separation(TIPS).Phase diagram of PVDF/[BMIM]PF6 was measured.The effects of polymer concentration and quenching temperature on the morphologies,properties,and performances of the PVDF membranes were investigated.When the polymer concentration was 15 wt%,the pure water flux of the fabricated membrane was up to nearly 2000 L·m-2·h-1,along with adequate mechanical strength.With the increasing of PVDF concentration and quenching temperature,mean pore size and water permeability of the membrane decreased.SEM results showed that PVDF membranes manufactured by ionic liquid(BMIm PF6)presented spherulite structure.And the PVDF membranes were represented asβphase by XRD and FTIR characterization.It provides a new way to prepare PVDF membranes with piezoelectric properties. | Xiaozu Wang Xiaogang Li Juan Yue Yangming Cheng Ke Xu Qian Wang Fan Fan Zhaohui Wang Zhaoliang Cui | 2020 | Chinese Journal of Chemical Engineering2020，28，5： | 4 |
| 8 | A Criterion on the Finite p-Nilpotent Groups显示文摘Let G be a finite group. Suppose that H is a subgroup of G. We say that H is s-semipermutable in G if HG_p = G_p H for any Sylow p-subgroup G_p of G with(p, |H|) = 1,where p is a prime dividing the order of G. We give a p-nilpotent criterion of G under the hypotheses that some subgroups of G are s-semipermutable in G. Our result is a generalization of the famous Burnside's p-nilpotent criterion. | Xiangyang XU Yangming LI | 2019 | Journal of Mathematical Research with Applications2019，39，3： | 3 |
| 9 | Pluripotency-associated miR-290/302 family of microRNAs promote the dismantling of naive pluripotency显示文摘 | Kai-Li Gu Qiang Zhang Ying Yan Ting-Ting Li Fei-Fei Duan Jing Hao Xi-Wen Wang Ming Shi Da-Ren Wu Wen-Ting Guo Yangming Wang | 2016 | Cell Research2016，26，3： | 3 |
| 10 | Urban-rural disparities in mild cognitive impairment and its functional subtypes among community- dwelling older residents in central China显示文摘background Substantial variations in the prevalence of mild cognitive impairment(MCI)and its subtypes have been reported,although mostly in geographically defined developed countries and regions.Less is known about MCI and its subtypes in rural areas of less developed central China.Aims The study aimed to compare the prevalence of MCI and its subtypes in residents aged 65 years or older in urban and rural areas of Hubei Province,China.Methods Participants aged 65 years or older were recruited between 2018 and 2019.Inperson structured interviews and clinical and neuropsychological assessments were performed at city health community centres and township hospitals.results Among 2644 participants without dementia,735 had MCI,resulting in a prevalence of 27.8%for total MCI,20.9%for amnestic MCI(aMCI)and 6.9%for non-amnestic MCI(naMCI).The prevalence of MCI in urban and rural areas was 20.2%and 44.1%,respectively.After adjusting for demographic factors,the prevalence of total MCI,aMCI and naMCI differed significantly between rural and urban areas(adjusted odds ratio(OR)2.10,1.44 and 3.76,respectively).Subgroup analysis revealed an association between rural socioeconomic and lifestyle disadvantage and MCI and its subtypes.Conclusions Our findings suggest that the prevalence of MCI among urban residents in central China is consistent with that in other metropolis areas,such as Shanghai,but the prevalence in rural areas is twice that in urban areas.Prospective studies and dementia prevention in China should focus on rural areas. | Dan Liu Lin Li Lina An Guirong Cheng Cong Chen Mingjun Zou Bo Zhang Xuguang Gan Lang Xu Yangming Ou Qingming Wu Ru Wang Yan Zeng | 2021 | General Psychiatry2021，34，5： | 3 |
| 11 | Experimental study on the impact of temperature on the dissipation process of supersaturated total dissolved gas显示文摘Water temperature not only affects the solubility of gas in water but can also be an important factor in the dissipation process of supersaturated total dissolved gas(TDG).The quantitative relationship between the dissipation process and temperature has not been previously described.This relationship affects the accurate evaluation of the dissipation process and the subsequent biological effects.This article experimentally investigates the impact of temperature on supersaturated TDG dissipation in static and turbulent conditions.The results show that the supersaturated TDG dissipation coefficient increases with the temperature and turbulence intensity.The quantitative relationship was verified by straight flume experiments.This study enhances our understanding of the dissipation of supersaturated TDG.Furthermore,it provides a scientific foundation for the accurate prediction of the dissipation process of supersaturated TDG in the downstream area and the negative impacts of high dam projects on aquatic ecosystems. | Xia Shen Shengyun Liu Ran Li Yangming Ou | 2014 | Journal of Environmental Sciences2014，26，9： | 3 |
| 12 | Kinematics and Inverse Dynam- ics Analysis for a General 3-RPS Spatial Parallel Mecha- nism 显示文摘 | LI Yangming XU Qingsong | 2005 | Robotics2005，23，： | 1 |
| 13 | Development of the novel ACLY inhibitor 326E as a promising treatment for hypercholesterolemia显示文摘Hepatic cholesterol accumulation is an important contributor to hypercholesterolemia,which results in atherosclerosis and cardiovascular disease(CVD).ATP-citrate lyase(ACLY)is a key lipogenic enzyme that converts cytosolic citrate derived from tricarboxylic acid cycle(TCA cycle)to acetyl-CoA in the cytoplasm.Therefore,ACLY represents a link between mitochondria oxidative phosphorylation and cytosolic de novo lipogenesis.In this study,we developed the small molecule 326E with an enedioic acid structural moiety as a novel ACLY inhibitor,and its CoA-conjugated form 326E-CoA inhibited ACLY activity with an IC_(50)=5.31±1.2μmol/L in vitro.326E treatment reduced de novo lipogenesis,and increased cholesterol efflux in vitro and in vivo.326E was rapidly absorbed after oral administration,exhibited a higher blood exposure than that of the approved ACLY inhibitor bempedoic acid(BA)used for hypercholesterolemia.Chronic 326E treatment in hamsters and rhesus monkeys resulted in remarkable improvement of hyperlipidemia.Once daily oral administration of 326E for 24 weeks prevented the occurrence of atherosclerosis in ApoE^(-/-)mice to a greater extent than that of BA treatment.Taken together,our data suggest that inhibition of ACLY by 326E represents a promising strategy for the treatment of hypercholesterolemia. | Zhifu Xie Mei Zhang Qian Song Long Cheng Xinwen Zhang Gaolei Song Xinyu Sun Min Gu Chendong Zhou Yangming Zhang Kexin Zhu Jianpeng Yin Xiaoyan Chen Jingya Li Fajun Nan | 2023 | Acta Pharmaceutica Sinica B2023，13，2： | 1 |
| 14 | The fate of CO 2 derived from thermochemical sulfate reduction (TSR) and effect of TSR on carbonate porosity and permeability, Sichuan Basin, China显示文摘 | Fang Hao Xuefeng Zhang Cunwu Wang Pingping Li Tonglou Guo Huayao Zou Yangming Zhu Jianzhang Liu Zhongxian Cai | 2014 | Earth-Science Reviews2014，，： | 1 |
| 15 | Glycosylation and an amino acid insertion in the head of hemagglutinin independently affect the antigenic properties of H5N1 avian influenza viruses显示文摘Antigenic drift forces us to frequently update influenza vaccines; however, the genetic basis for antigenic variation remains largely unknown. In this study, we used clade 7.2 H5 viruses as models to explore the molecular determinants of influenza virus antigenic variation. We generated eight monoclonal antibodies(MAbs) targeted to the hemagglutinin(HA) protein of the index virus A/chicken/Shanxi/2/2006 and found that two representative antigenically drifted clade 7.2 viruses did not react with six of the eight MAbs. The E131 N mutation and insertion of leucine at position 134 in the HA protein of the antigenically drifted strains eliminated the reactivity of the virus with the MAbs. We also found that the amino acid N131 in the H5 HA protein is glycosylated. Our results provide experimental evidence that glycosylation and an amino acid insertion or deletion in HA influence antigenic variation. | Chunyang Gu Xianying Zeng Yangming Song Yanbing Li Liling Liu Yoshihiro Kawaoka Dongming Zhao Hualan Chen | 2019 | Science China(Life Sciences)2019，62，1： | 1 |
| 16 | The influence of π - quasinormality of some subgroups of a finite group 显示文摘 | LI Yangming WANG Yarnming WEI Huaquan | 2003 | Arch Math2003，，81： | 1 |
| 17 | The influence of $\pi$-quasinormality of some subgroups of a finite group显示文摘 | Yangming Li Yanming Wang Huaquan Wei | 2003 | Archiv der Mathematik2003，，3： | 1 |
| 18 | A biologically inspired solution to simultaneous localization and consistent mapping in dynamic environments显示文摘 | Yangming Li Shuai Li Yunjian Ge | 2012 | Neurocomputing2012，，： | 1 |
| 19 | A criterion of p -hypercyclically embedded subgroups of finite groups显示文摘 | Ning Su Yangming Li Yanming Wang | 2014 | Journal of Algebra2014，，： | 1 |
| 20 | Taihu Lake not to blame for Wuxi's woes 显示文摘 | YangM Yu J W Li Z L | 2008 | Science2008，319，5860： | 1 |
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