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| 1 | Gastrodin blocks neural stem cell differentiation into glial cells mediated by kainic acid显示文摘Kainic acid can simulate excitatory amino acids in vitro.Neural stem cells,isolated from newborn Wistar rats,were cultured in vitro and exposed to 100-4 000 μM kainic acid for 7 days to induce neuronal cell differentiation,causing the number of astrocytes to be significantly increased.Treatment with a combination of 0.5 mg/L gastrodin and kainic acid also caused the number of differentiated neurons to be significantly increased compared with treatment with kainic acid alone.Experimental findings suggest that gastrodin reduces the excitability of kainic acid and induces neural stem cell differentiation into neurons. | Guifang Sun Zhihao Yuan Boai Zhang Yanjie Jia Yangfei Ji Xingrong Ma Yu Liu Yanru Liu Quanqing Wen Yanling Zhao | 2012 | Neural Regeneration Research2012,7,12: | 4 |
| 2 | Microstructures, mechanical properties and corrosion resistance of Hastelloy C22 coating produced by laser cladding 显示文摘 | Qinying Wang Yangfei Zhang Shulin Bai | 2013 | Journal of Alloys and Compounds2013,553,3: | 1 |
| 3 | 显示文摘 | DUKe(杜柯) HUANGXia(黄霞) YANGFei(杨菲) etal | | WujiHuaxueXuebao0,,: | 1 |
| 4 | 显示文摘 | YANGFei SUNJiu-lin ZHANGBai etal(杨飞 孙九林 张柏 等) | 2010 | 农业工程学报2010,26,4: | 1 |
| 5 | 显示文摘 | DUKe(杜柯) HUANGXia(黄霞) YANGFei(杨菲) etal | | WujiHuaxueXnebao0,,: | 1 |
| 6 | lng-term prognosis of acute kidney injury after acute myocardial infarction 显示文摘 | Parikh CR Coca SG Wang Yangfei | 2008 | Arch Intern Med2008,168,9: | 1 |
| 7 | 显示文摘 | DVKe(杜柯) HVANGXia(黄霞) YANGFei(杨菲) etal | | WujiHuaxueXuebao0,,: | 1 |
| 8 | ThestudyofZn2+/Ag+compoundinorganicantisepticwithsepioliteasthecarri-er显示文摘 | LiuJing LuYu YangFei etal | 2013 | JournalofFunctionalMaterials2013,44,4: | 1 |
| 9 | Molecular and multidimensional organic-inorganic hybrids based on poly- oxometalates and copper coordination polymer with mixed 4,4'-bipyridine and 2, 2'-bipyridine ligands 显示文摘 | Jin Hua Qi Yangfei Wang Enbo | 2006 | Cryst Growth Des2006,6,12: | 1 |
| 10 | AquantitativemethodforsimultaneousassayoffiveingredientswithonemarkerinSalviamiltiorrhiza('一测多评'法测定丹参酚酸类成分的含量)显示文摘 | YANGFei(杨菲) WANGZhi-min(王智民) ZHANGQi-wei(张启伟) etal | 2011 | ChinaJ中国中药杂志2011,,17: | 1 |
| 11 | pH-sensitive poly(glutamic acid) grafted mesoporous silica nanoparticles for drug delivery显示文摘 | Jin Zheng Xuejiao Tian Yangfei Sun Daru Lu Wuli Yang | 2013 | International Journal of Pharmaceutics (-)2013,,1: | 1 |
| 12 | Analysis of Gene Expression Profile in Lung Adenosquamous Carcinoma Using cDNA Microarray显示文摘Gene expression profile of the lung adenosquamous carcinoma was characterized by using cDNA microarray chip containing 4 096 human genes. Among target genes, 508 differentially expressed genes were identified in adenosquamous carcinoma of the lung, 232 genes were overexpressed and 276 genes were underexpressed. Among them, 92 genes are cell signals transduction genes, 34 genes are proto-oncogenes and tumor suppressor genes or cell cycle related genes or cell apoptosis related genes, 29 genes are cell skeleton genes, 28 genes are DNA synthesis, repair and recombination genes, 12 genes are DNA binding and transcription genes. These genes may be associated with the occurence and development of adenosquamous carinome of the lung. | YANGFei YANGJiong JIANGMan YEBo ZHANGYu-xia CHENHong-lei XIADong LIUMing-qiu | 2004 | Wuhan University Journal of Natural Sciences2004,9,6: | 0 |
| 13 | Modeling human neurodevelopmental diseases with brain organoids显示文摘Studying the etiology of human neurodevelopmental diseases has long been a challenging task due to the brain’s complexity and its limited accessibility.Human pluripotent stem cells(hPSCs)-derived brain organoids are capable of recapitulating various features and functionalities of the human brain,allowing the investigation of intricate patho-genesis of developmental abnormalities.Over the past years,brain organoids have facilitated identifying disease-associated phenotypes and underlying mechanisms for human neurodevelopmental diseases.Integrating with more cutting-edge technologies,particularly gene editing,brain organoids further empower human disease modeling.Here,we review the latest progress in modeling human neurodevelopmental disorders with brain organoids. | Xiaoxiang Lu Jiajie Yang Yangfei Xiang | 2022 | Cell Regeneration2022,11,1: | 0 |
| 14 | National Security Legislation Set to Bolster HK Stability显示文摘CHINA’S top legislature approved a decision on May 28 on establishing and improving the legal system and enforcement mechanisms for the Hong Kong Special Administrative Region to safeguard national security.The national security legislation for the Hong Kong SAR is designed to ensure steady implementation of“one country,two systems”in the SAR as well as uphold its long-term stability and prosperity,Premier Li Keqiang said at a news conference following the closure of the third session of the 13th National People’s Congress. | ZHANG YANGFEI | 2020 | China Today2020,69,6: | 0 |
| 15 | Protective effects of gastrodine on dendritic spines in kainic acid-injured neurons显示文摘EphB2 affects neuronal cells by altering the dendritic spines. The present study analyzed the neu-roprotective effects of gastrodine by measuring EphB2 expression in rat neural cells cultured in vitro and injured by kainic acid. Gastrodine (12.5, 25, and 50 mg/L) improved morphology in kainic acid-injured neurons, reduced lactate dehydrogenase leakage, decreased neuronal apoptosis, and increased EphB2 expression in neuronal cells. A moderate dose of 25 mg/L gastrodine resulted in the most significant effects. These results suggested that gastrodine suppressed the neurotoxic effects of excitatory amino acids and provided neuroprotection by remodeling neuronal dendritic spines. | Yangfei Ji Boai Zhang Yanjie Jia Guifang Sun Yu Liu Tao Peng Yanru Liu Xingrong Ma | 2011 | Neural Regeneration Research2011,6,36: | 0 |
| 16 | 太空计划展览在北京开幕显示文摘中国载人航天工程发展互动科普展在北京中国科技馆向公众开放。此次“飞向太空”科普展是为了庆祝中国共产党成立100周年,它让参观者体验到了太空飞行的刺激感受。它展示了宇航员的工作,时间隧道和在太空中的生活。 | Zhang Yangfei 高齐云(选译) | 2021 | 中学生英语2021,,21: | 0 |
| 17 | Integration of biosafety surveillance through Biosafety Surveillance Conceptual Data Model显示文摘The global movement of people and goods has increased the risk of biosecurity threats and their potential to induce large economic,social,and environmental harm.Integration of biosafety monitoring networks has become a top priority for addressing biosafety issues.In order to resolve the data standards and integration problems in the field of biosafety in China,the Biosafety Surveillance Conceptual Data Model(BSCDM),which is an object-oriented,hierarchically designed,flexible and scalable biosafety surveillance concept data model,is proposed in this article.This model is based on the integration of business process management and data resources of disease surveillance,animal disease surveillance and potential invasive biological monitoring.In reference to the Public Health Conceptual Data Model(PHCDM)and Federal Enterprise Architecture(FEA),BSCDM conducts a thorough analysis of biosafety monitoring activities,records basic information requirements of biosafety monitoring and provides data set standards for biosafety-related activities.It is developed with the Unified Modeling Language(UML)and could be applied as an open standard for accelerating data analysis and promoting collaboration.This study attempts to integrate biosafety monitoring data and the presented model has been tested in the detection of dengue fever in China and will be applied to other biosafety fields. | Wang Songwang Li Yangfei Chen Qiang Feng Xiaoyu Shi Xiju Huang Ying Mei Li Li Wei Liu Haizhou Qi Xiaopeng Liu Di | 2019 | Biosafety and Health2019,1,2: | 0 |
| 18 | Stimulating and harnessing circularly polarized luminescence of helically assembled carbonized polymer dots via interfacial dynamics显示文摘Stimulating and harnessing circularly polarized luminescence(CPL)is not only a sine qua non for fundamentally unveiling chirogenesis in physical chemistry,but also a pivotal prerequisite for implementation of such phenomenon in research fields including chiral optoelectronics and theranostics.Herein,red-emissive carbonized polymer dots(CPDs)-based helical structures were synthesized in this work via biomolecule-tailored organic–inorganic co-assembly strategy.The surface statesrelated chirality exhibits enhanced circular dichroism(CD)and CPL activities with anisotropic factors as high as gCD,max=5.4×10^(−3) and glum,max=1.5×10^(−2),respectively.The obtained CPL signals can be further manipulated in an excitationdependent manner,indicating that a synergistic-competition phenomenon exists between configurational chirality and intermolecular energy-transfer dynamics,which is further supported by simulations based on density function theory(DFT).Such tunable CPL behavior triggers revolutionary designs and applications of these chiral CPDs into the realm of chirality-related biological issues and next-generation chiral optoelectronics. | Jiaying Lin Rulin Liu Peixian Chen Yangfei Lv Junjie Hao Meijuan Chen Dongxiang Zhang Ruikun Pan Yiwen Li Xi Zhu Tingchao He Jiaji Cheng | 2023 | Aggregate2023,4,4: | 0 |
| 19 | Simulations of ultra-high sensitivity RI sensor in triple-core fiber with modified Vernier effect:Application in marine RI measurement显示文摘We proposed an ultra-high sensitivity triple-core fiber refractive index(RI)sensor with a modified Vernier effect for marine RI measurement and demonstrated it by numerical simulation.This sensor composes a pair of parallelized spatial mode Mach-Zehnder interferometers(MZIs),both of which are involved in sensing,but possess different interfering modes.By designing an MZI RI fiber optic sensor based on Vernier effect in air,it is demonstrated that in the low RI such as air environment,only the modes involved in sensing interference are affected by the environment to generate Vernier effect.In the high RI marine environment,both sensing interferometer and reference interferometer need to be affected by the ambient RI to generate Vernier effect.The simulation results indicate that the proposed novel sensing structure can amplify its sensitivity from-15428 nm/RIU to-24857 nm/RIU in the marine environment. | XIONG Lingyi YU Yangfei DUAN Shaoxiang LIU Bo LIN Wei YAO Yuan | 2023 | Optoelectronics Letters2023,19,8: | 0 |
| 20 | Identification of proteasome and caspase inhibitors targeting SARS-CoV-2 Mpro显示文摘Dear Editor,Since the beginning of 2020,the Coronavirus(CoV)Disease 2019(COVID-19)pandemic has posed formidable challenges to public health security.The main protease(Mpro,3CLpro)of CoVs plays essential roles in viral replication,making them attractive targets for antiviral drug development. | Zhengyuan Wang Yao Zhao Qingxing Wang Yangfei Xing Lu Feng Juan Kong Chao Peng Leike Zhang Haitao Yang Min Lu | 2021 | Signal Transduction and Targeted Therapy2021,6,7: | 0 |