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| 1 | Relationship between air temperature oscillations and solar variability on short and medium time scales显示文摘The contemporary science of climate change is increasingly focusing on the temporal and spatial characteristics of temperature oscillations and determining possible underlying causes.In particular,the effect of variations in solar irradiance on the variability of the climate remains a hot topic of debate.Most studies focus on the effects of solar variation on the Earth's climate on long time scales.This study presents the responses of regional climates to solar variations on shorter time scales using two datasets:one for the air temperature in Nanjing and the Greenwich sunspot number,and the other for the air temperature in Shijiazhuang and the United States sunspot number.Employing empirical mode decomposition,both the 11-year quasi-period of the sunspot number and similar periods including approximately 5.5-and 10.5-year cycles of the air temperature in Nanjing and Shijiazhuang are obtained.However,correlation analysis of similar periodic components for the sunspot number and air temperature indicates that changes in the air temperature on short and medium time scales are not linked to solar variations.This is further confirmed by a test of whether a mode component is a stochastic noise signal.Many shorter periods are also found at the 95% confidence level;in particular,the 3.1-year period of the Nanjing air temperature coincides with a previously obtained empirical result.Moreover,no temperature variations on shorter time scales correlate with solar variability. | YANG ChunXia WU HongFa HU DanTing | 2011 | Science China Earth Sciences2011，54，6： | 6 |
| 2 | 结合风险矩阵和故障树分析法的海洋地震测量船运营的规范化安全评估显示文摘In maritime safety research,risk is assessed usually within the framework of formal safety assessment(FSA),which provides a formal and systematic methodology to improve the safety of lives,assets,and the environment.A bespoke application of FSA to mitigate accidents in marine seismic surveying is put forward in this paper,with the aim of improving the safety of seismic vessel operations,within the context of developing an economically viable strategy.The work herein takes a close look at the hazards in North Sea offshore seismic surveying,in order to identify critical risk factors,leading to marine seismic survey accidents.The risk factors leading to undesirable events are analysed both qualitatively and quantitatively.A risk matrix is introduced to screen the identified undesirable events.Further to the screening,Fault Tree Analysis(FTA)is presented to investigate and analyse the most critical risks of seismic survey operation,taking into account the lack of historical data.The obtained results show that man overboard(MOB)event is a major risk factor in marine seismic survey operation;lack of training on safe work practice,slippery deck as a result of rain,snow or water splash,sea state affecting human judgement,and poor communication are identified as the critical risk contributors to the MOB event.Consequently,the risk control options are focused on the critical risk contributors for decision-making.Lastly,suggestions for the introduction and development of the FSA methodology are highlighted for safer marine and offshore operations in general. | Gregory Asuelimen Eduardo Blanco-Davis Jin Wang Zaili Yang Dante Benjamin Matellini | 2020 | Journal of Marine Science and Application2020，19，2： | 2 |
| 3 | PD0325901, an ERK inhibitor, enhances the efficacy of PD-1 inhibitor in non-small cell lung carcinoma显示文摘ERK pathway regulated the programmed death ligand-1(PD-L1)expression which was linked to the response of programmed death-1(PD-1)/PD-L1 blockade therapy.So it is deducible that ERK inhibitor could enhance the efficacy of PD-1 inhibitor in cancer immunotherapy.In this study,PD0325901,an oral potent ERK inhibitor,strongly enhanced the efficacy of PD-1 antibody in vitro and in vivo models in non-small cell lung carcinoma(NSCLC)cells.Mechanistically,PD0325901 or shRNA-ERK1/2 significantly downregulated the PD-L1 expression in NSCLC cells and increased the CD3+T cells infiltration and functions in tumor tissue.There was a positive correlation between the p-ERK1/2 expression and PD-L1 expression in patients with NSCLC.And the patients with low p-ERK1/2 expression were observed a high response rate of PD-1/PD-L1 blockage therapy.Our results demonstrate that PD0325901,an ERK inhibitor,can enhance the efficacy of PD-1 blockage against NSCLC in vitro and in vivo models.And the combination of ERK inhibitor such as PD0325901 and PD-1/PD-L1 blockage is a promising regimen and encouraged to be further confirmed in the treatment of patients with NSCLC. | Min Luo Yuhui Xia Fang Wang Hong Zhang Danting Su Chaoyue Su Chuan Yang Shaocong Wu Sainan An Suxia Lin Liwu Fu | 2021 | Acta Pharmaceutica Sinica B2021，11，10： | 1 |
| 4 | Applications of Raman Spectroscopy in Agricultural Products and Food Analysis: A Review显示文摘 | Danting Yang Yibin Ying | 2011 | Applied Spectroscopy Reviews2011，，7： | 1 |
| 5 | Determination of Amino Acids in Chinese Rice Wine by Fourier Transform Near - Infrared Spec- troscopy显示文摘 | Fei Shen Xiaoying Niu Danting Yang | 2010 | Agricultural And Food Chemistry2010，58，17： | 1 |
| 6 | Discrimination between Shaoxing wines and other Chinese rice wines by near-infrared spectroscopy and chemo metrics显示文摘 | SHEN Fei YANG Danting YING Yibin | 2012 | Food and Bioprocess Technology2012，5，2： | 1 |
| 7 | Evolution and homologous recombination of the hemagglutinin–esterase gene sequences from porcine torovirus显示文摘 | Yingying Cong Dante S. Zarlenga Juergen A. Richt Xin Wang Yang Wang Siqingaowa Suo Jingfei Wang Yudong Ren Xiaofeng Ren | 2013 | Virus Genes2013，，1： | 1 |
| 8 | Evaluationof Rice Germplasm from Southeast Asia显示文摘 | Danting LI Baoxuan NONG Xiuzhong XIA Kaiqiang LIU Qingwen YANG Zongwen ZHANG Guoqing GAO | 2012 | Agricuhural Science & Technology2012，13，21： | 1 |
| 9 | Determination of aminoacids in Chinese rice wine by fourier transform near-infrared spectroscopy显示文摘 | Shen Fei Niu Xiaoying Yang Danting | 2010 | Agr Food Chem2010，58，17： | 1 |
| 10 | OsNPF3.1,a member of the NRT1/PTR family,increases nitrogen use efficiency and biomass production in rice显示文摘The overuse of nitrogen(N)fertilizer in fields has increased production costs and raised environmental concerns.Increasing the N use efficiency(NUE)of rice varieties is crucial for sustainable agriculture.Here we report the cloning and characterization of OsNPF3.1,a gene that controls rice NUE.An amino acid mutation in the OsNPF3.1 coding region caused different NUEs in wild and cultivated rice.OsNPF3.1,which is expressed mainly in the aerial parts of rice,also affects rice plant height,heading date,and thousand-grain weight.The OsNPF3.1 protein is located in the plasma membrane.When OsNPF3.1 was subjected to artificial selection,two naturally varying loci were associated with NUE,of which OsNPF3.1Chr6_8741040differed between indica and japonica rice.OsNPF3.1 can be used as a new target gene for breeding rice varieties with high NUE. | Xinghai Yang Baoxuan Nong Can Chen Junrui Wang Xiuzhong Xia Zongqiong Zhang Yu Wei Yu Zeng Rui Feng Yanyan Wu Hui Guo Haifeng Yan Yuntao Liang Shuhui Liang Yong Yan Danting Li Guofu Deng | 2023 | The Crop Journal2023，11，1： | 0 |
| 11 | Limosilactobacillus mucosae FZJTZ26M3 prevents NAFLD in mice through modulation of lipid metabolism and gut microbiota dysbiosis显示文摘Lactobacillus are considered promising therapeutic methods for nonalcoholic fatty liver disease(NAFLD).The effects of two strains of Ltmosilactobacillus mucosae on NAFLD were investigated in this study.Fourweek-old male C57BL/6J mice were divided into 4 groups(n=8 per group,Control,Model,FZJTZ26M3,FGSYC17L3).L.mucosae FZJTZ26M3 reduced the mice 's body weight,liver weight,and adipose tissue weight after 12 weeks of therapy.According to serum analysis,total cholesterol,triacylglycerol,and low-density lipoprotein cholesterol significantly decreased after L.mucosae FZJTZ26M3 intervention.Liver pathology showed that L.mucosae FZJTZ26M3 was effective to ameliorate lipid deposition in NAFLD mice.Additionally,the expression of the gene related to lipid metabolism in the liver and adipose tissue was analyzed,and the results indicated that L.mucosae FZJTZ26M3 could alleviate NAFLD by regulating lipid metabolism.Furthermore,the results of 16S rRNA gene sequencing revealed a drop in the relative abundance of Ruminococcaceae,which is linked to inflammation,but the relative abundance of a potential probiotic Akkermansia significantly increased after L.mucosae FZJTZ26M3 intervention.Generally,L.mucosae FZJTZ26M3 could be a candidate to prevent NAFLD. | Danting Dang Bowen Li Mengfan Ding RPaul Ross Catherine Stanton Jianxin Zhao Bo Yang Wei Chen | 2024 | Food Science and Human Wellness2024，13，3： | 0 |
| 12 | Validation of the Red Pericarp Gene from 419 Rice Landraces in Guangxi via Genome-wide Association Studies显示文摘Rice has different colors of pericarp,such as red,white and black. Red rice pericarp is rich in proanthocyanins,which have antioxidant properties and are beneficial to human health. In the present study,we analyzed the red-pericarp gene Rc of 419 rice landraces in Guangxi by genome-wide association study( GWAS),and validated that the Rc gene regulated the red pericarp trait in rice. By analyzing the genomic DNA of 97 red-pericarp rice cultivars,we identified two new alleles in C139 and C323. Then,the exons of Rc^(C139) and Rc^(C323) were sequenced with Sanger method,and the results demonstrated that the natural mutations within Rc gene resulted in the two alleles Rc^(C139) and Rc^(C323). | Zongqiong ZHANG Xinghai YANG Baoxuan NONG Xiuzhong XIA Yu ZENG Kaiqiang LIU Guofu DENG Danting LI | 2017 | Agricultural Biotechnology2017，6，3： | 0 |
| 13 | Transcriptome analysis reveals potential genes associated with plant height in rice显示文摘Plant height(PH)is a complex trait regulated by the environment and multiple genes.PH directly affects crop yield,harvest index,and lodging resistance.From plant dwarf mutants,many genes related to PH have been identified and described.Nonetheless,the molecular mechanism of height regulation in high-culm rice mutants has not been well studied.By using transcriptome and weighted gene co-expression network analysis(WGCNA),we identified the differentially expressed genes(DEGs)between high-culm rice mutants(MUT)and wild-type(WT)and explored the key pathways and potential candidate genes involved in PH regulation.Transcriptome analysis identified a total of 2,184 DEGs,of which 1,317 were identified at the jointing stage and 1,512 were identified at the heading stage.Kyoto Encyclopedia of Genes and Genomes enrichment showed that the enrichment pathways were mainly involved in plant hormone signal transduction,ABC transportation,and steroid hormone biosynthesis.Among these metabolic pathways,LOC_Os05g43910 and LOC_Os01g35030 were auxin(IAA)-related genes,up-regulated in MUT and LOC_Os02g08500(LEPTO1),LOC_Os11g04720,and LOC_Os12g04500 were cytokinin(CK)-related genes,downregulated in MUT.The WGCNA identified four modules(light cyan,dark grey,grey,and pale turquoise)closely related to PH,and seven key genes were screened from these modules,of which two were up-regulated cell wallrelated genes(LOC_Os01g26174(OsWAK5),LOC_Os06g05050)in MUT,and one gibberellic acid(GA)gene(LOC_Os06g37364,OsKO2)was also up-regulated.These genes might be closely related to PH regulation.These findings help us better understand the transcriptional regulation of rice plant growth and development and provide a theoretical basis for mapping and cloning the PH regulatory genes. | CAN CHEN RUI FENG ZONGQIONG ZHANG XIUZHONG XIA BAOXUAN NONG YU ZENG HUI GUO XINGHAI YANG DANTING LI | 2023 | BIOCELL2023，47，2： | 0 |
| 14 | Construction of biomimetic proton transport channels in metal-organic framework显示文摘Construction of proton transport channels in metal-organic frameworks(MOFs)with simple synthesis processes,high proton conductivities and good performance stabilities has been of great interest for proton exchange membrane fuel cell(PEMFC).Herein,we mimic the proton transport behavior of amino acid residues in bacteriorhodopsin,select UiO-66-COOH as the host,glycine and aspartic acid as the functional guest molecules,and then functionalize the MOF framework with amino acids to obtain biomimetic proton transport channels.This strategy endows UiO-66-COOH-Asp a high proton conductivity of 1.19×10^(-2)S/cm at 70℃and 98%RH,excellent cycle stability of performances and performance durability,which can be comparable to the reported MOFs-based proton conductors.Moreover,the proton conduction mechanism in UiO-66-COOH-Asp is elaborated in detail due to its visual structure,which is also one of the advantages of adopting MOFs as research platform,making it possible to optimize the structure-activity relationship of advanced materials.Notably,this strategy has clear objectives and simple synthesis,which has made certain contributions to both theoretical research and future industrial production of proton conductors. | Xiao-Min Li Junchao Jia Danting Yang Jiali Jin Junkuo Gao | 2024 | Chinese Chemical Letters2024，35，3： | 0 |
| 15 | Genome-wide selection and introgression of Chinese rice varieties during breeding显示文摘China is the largest rice-producing country,but the genomic landscape of rice diversity has not yet been clarified.In this study,we re-sequence 1070 rice varieties collected from China(400)and other regions in Asia(670).Among the six major rice groups(aus,indica-I,indica-II,aromatic,temperate japonica,and tropical japonica),almost all Chinese varieties belong to the indica-II or temperate japonica group.Most Chinese indica varieties belong to indica-II,which consists of two subgroups developed during different phases of rice breeding.The genomic segments underlying the differences between these subgroups span36.32 Mb.The Chinese japonica rice varieties fall into the temperate japonica group,consisting of two subgroups based on their geographical distribution.The genomic segments underlying the differences between these subgroups span 27.69 Mb.These differentiated segments in the Chinese indica varieties span 45 genes with nonsynonymous mutations that are closely related to variations in plant height and grain width.Fifty-four genes with nonsynonymous mutations are associated with the differences in heading date between the two Chinese japonica subgroups.These findings provide new insights into rice diversity in China that will facilitate the molecular breeding. | Jinyue Ge Junrui Wang Hongbo Pang Fei Li Danjing Lou Weiya Fan Ziran Liu Jiaqi Li Danting Li Baoxuan Nong Zongqiong Zhang Yanyan Wang Jingfen Huang Meng Xing Yamin Nie Xiaorong Xiao Fan Zhang Wensheng Wang Jianlong Xu Sung Ryul Kim Ajay Kohli Guoyou Ye Weihua Qiao Qingwen Yang Xiaoming Zheng | 2022 | Journal of Genetics and Genomics2022，49，5： | 0 |
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