|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Identification and characterization of microRNAs in raw milk during different periods of lactation, commercial fluid, and powdered milk products显示文摘最近的婴儿的公式奶粉污染事件证明了在牛奶质量控制的经典标记或标准在识别鈥渕a nipulated 鈥 ? 是不够的差质量的牛奶。在现在的学习,我们第一次证明奶牛牛奶包含大量 microRNAs ( miRNAs )并且牛奶特定的 miRNAs 的唯一的表示侧面能为未加工的牛奶和牛奶相关的商业产品的质量控制用作新奇指示物和可能的新标准,例如液体牛奶和粉状的公式牛奶。用定序的 Solexa,首先,我们系统地在未加工的牛奶屏蔽了 miRNA 表示并且在未加工的牛奶识别了 245 miRNAs 的一个总数。不同于层次在哺乳的不同时期是其表达式将近相同的另外的经典 biomarkers,单个 miRNAs 能显著地在哺乳过程期间被改变,含有那 miRNAs 可以是更精确的指示物反映牛奶的优秀改变。第二,使用 TaqMan 基于探查的 miRNA 量的 RT-PCR ,我们进一步识别了七 miRNAs 重要地在整个哺乳过程,和更多有相对一致的表情,这七牛奶特定的 miRNAs 的表示侧面能为区别用作理想的 biomarker 差质量或从纯未加工的牛奶的 鈥渕a nipulated 鈥?牛奶,象为商业乳制品的质量控制一样,例如液体,牛奶和粉状的公式挤。一起,我们的调查结果为为决定未加工的牛奶或牛奶相关的商业产品的质量理解牛奶 miRNAs 和一个新潜在的标准的生理的角色提供一个基础。 | Xi Chen Chao Gao Haijin Li Lei Huang Qi Sun Yanye Dong Chunliang Tian Shengpu Gao Hailin Dong Danping Guan Xiaoyun Hu Shujian Zhao Liang Li Lin Zhu Qiao Yan Junfeng Zhang Ke Zen Chen-Yu Zhang | 2010 | Cell Research2010，20，10： | 29 |
| 2 | Coinfection with influenza A virus enhances SARS-CoV-2 infectivity显示文摘The upcoming flu season in the Northern Hemisphere merging with the current COVID-19 pandemic raises a potentially severe threat to public health.Through experimental coinfection with influenza A virus(IAV)and either pseudotyped or live SARS-CoV-2 virus,we found that IAV preinfection significantly promoted the infectivity of SARS-CoV-2 in a broad range of cell types.Remarkably,in vivo,increased SARS-CoV-2 viral load and more severe lung damage were observed in mice coinfected with IAV.Moreover,such enhancement of SARS-CoV-2 infectivity was not observed with several other respiratory viruses,likely due to a unique feature of IAV to elevate ACE2 expression.This study illustrates that IAV has a unique ability to aggravate SARS-CoV-2 infection,and thus,prevention of IAV infection is of great significance during the COVID-19 pandemic. | Lei Bai Yongliang Zhao Jiazhen Dong Simeng Liang Ming Guo Xinjin Liu Xin Wang Zhixiang Huang Xiaoyi Sun Zhen Zhang Lianghui Dong Qianyun Liu Yucheng Zheng Danping Niu Min Xiang Kun Song Jiajie Ye Wenchao Zheng Zhidong Tang Mingliang Tang Yu Zhou Chao Shen Li Zhou Yu Chen Huan Yan Ke Lan Ke Xu | 2021 | Cell Research2021，31，4： | 16 |
| 3 | The Pengguan tectonic dome of Longmen Mountains, Sichuan Province:Mesozoic denudation of a Neoproterozoic magmatic arc-basin system显示文摘Neoproterozoic igneous and metamorphic complexes occur as tectonic domes in the Longmen Mountains of the western margin of the Yangtze Block, and are important in reconstructing the Rodinian supercontinent and constraining the timing and mechanism of tectonic denudational processes. The Pengguan dome consists of granitic intrusions and metamorphic rocks of the Huangshuihe Group and is tectonically overlain by ductilly deformed Sinian to Paleozoic strata. The plutonic intrusions consist of granites with abundant amphibolite enclaves. New LA-ICP-MS zircon U-Pb dating yielded an emplacement age of 809±3 Ma and a protolith age of 844±6 Ma for the granite. The granitic rocks have geochemical signatures typical of A-type granites, indicating their formation under an extensional environment, by melting of newly formed tonalite-trondhjemite-granodiorite (TTG) rocks. A detachment fault, characterized by variable ductile shear deformation of S-C fabric and ESE-ward kinematics, separates the Pengguan dome from the Sinian-Paleozoic cover. 40Ar/39Ar dating of muscovite from the mylonite in the detachment fault of the dome demonstrates that ductile deformation occurred at ~160 Ma. This study indicates the existence of a Neoproterozoic magmatic arc-basin system, which was denudated by a Jurassic middle crustal ductile channel flow along the Longmenshan thrust belt. | YAN DanPing ZHOU MeiFu WEI GuoQing GAO JianFeng LIU ShaoFeng XU Ping SHI XiaoYing | 2008 | Science China Earth Sciences2008，51，11： | 9 |
| 4 | Early Cretaceous Post-Collisional Collapse of the Yidun Terrane: Geochronological and Geochemical Constraints from Calc-alkaline to Alkaline Basalts in Xiqiu Area, Southwest China显示文摘Several Cretaceous Carlin-like or hydrothermal gold deposits along the Garze-Litang suture zone and Early Cretaceous hydrothermal copper mineralization along the southeastern margin of the Songpan-Garze fold belt were presumed to have a magmatic heat source. However, no actual coeval magmatic events nearby were discovered. Here, we report zircon SIMS U-Pb age, whole-rock geochemical and Sr-Nd isotopic data of the Xiqiu basalts in the southern end of the Yidun terrane, eastern Tibetan Plateau. New zircon U-Pb ages yield weighted mean ^(206) Pb/^(238) U age of 117.7±1.6 Ma. The basalts are classified as calc-alkaline to alkaline and have relatively high Mg O(4.77 wt.%–10.84 wt.%) and Mg number values(Mg~#=(100×Mg/(Mg+Fe^(2+))); 45.35–67.28) and positive ε_(Nd)(t)(t=118 Ma) values(+1.86 to +3.2), suggesting a OIB-like mantle source that is consistent with the normalized patterns of trace elements and rare earth elements(REEs). Geochemical data suggest that the primary basaltic magma was generated by low degree partial melting of a peridotite-dominated mantle source with a minor component of garnet-eclogite or pyroxenite and experienced olivine+clinopyroxene dominated fractional crystallization. The primary melt compositions calculated from the high Mg O samples, in turn, suggest that the Xiqiu basalts were generated at 1.6–2.9 GPa with abnormally hot mantle potential temperatures from 1 465 to 1 540 oC. The melting temperatures are similar to the abnormally hot mantle underneath the Colorado Plateau and hotter than the mid-ocean range basalt(MORB) mantle and normal intra-continental mantle. Combined with previous studies, the Cretaceous Xiqiu basalts allow us to reconstruct a tectonic and geodynamic evolutionary model responsible for the Late Jurassic to Late Cretaceous geological records(magmatism, ore deposits and enhanced exhumation) in the Yidun terrane and southern Songpan-Garze fold belt. | Xutuo Li Danping Yan Liang Qiu | 2018 | Journal of Earth Science2018，29，1： | 6 |
| 5 | Well-construction of Zn_(2)SnO_(4)/SnO_(2)@ZIF-8 core-shell hetero-structure with efficient photocatalytic activity towards tetracycline under restricted space显示文摘Nowadays,efficient removal of antibiotic(e.g.tetracycline,TC) from water bodies has been of great global concern.Hereby,a novel Zn_(2)SnO_(4)/SnO_(2)@ZIF-8 photo-catalyst was first synthesized by a facile selfassembly in-situ growth method.Zn_(2)SnO_(4)/SnO_(2)@ZIF-8 exhibits a remarkable photocatalytic activity towards TC under visible-light driven with a rapid rate constant of 1.5 × 10^(-2)min^(-1), and a removal efficiency of 81.2%,which is superior to some catalysts in the literature.Importantly,the photocatalytic activity of Zn_(2)SnO_(4)/SnO_(2)@ZIF-8 could still remain ~77% after the fifth cycle,indicating its good stability and reusability.The remarkable performances of adsorption and photocatalytic were attributed to associative effects of catalytic activity of Zn_(2)SnO_(4)/SnO_(2)and the unique porous nanostructure and stability of ZIF-8.This work could aid the future design and preparation of novel MOFs composite catalysts for efficient elimination of antibiotics from water. | Jiafei Wu Yuning Jin Danping Wu Xiaoying Yan Na Ma Wei Dai | 2022 | Chinese Journal of Chemical Engineering2022，，12： | 3 |
| 6 | Blue revolution for food security under carbon neutrality: A case from the water-saving and drought-resistance rice显示文摘The increasing concentration of greenhouse gases(GHGs)in Earth's atmosphere leads to global warming,which further causes a series of climate changes and does great harm to both human society and natural ecosystems.Agricultural GHG emissions,mainly in theform of methane(CH4)and nitrous oxide(N2O),areasignificantsourceofGHGs,accountingfor~14%total global GHGs(Zhang et al.,2022).One major source of agricultural GHGs is CH4 emissions from rice paddies,which is responsiblefor~10%-12%ofhuman-inducedCH4emissions(van Groenigen et al.,2013)and contributes~2.40%to the enhanced global warming effect(Zhang et al.,2022).The global warming potential of GHGs emissions from rice systems is roughly four times higher than either wheat or maize(Linquist et al.,2012). | Hui Xia Xianxian Zhang Yi Liu Junguo Bi Xiaosong Ma Anning Zhang Hongyan Liu Liang Chen Sheng Zhou Huan Gao Kai Xu Haibin Wei Guolan Liu Feiming Wang Hongyang Zhao Xingxing Luo Danping Hou Qiaojun Lou Fangjun Feng Liguo Zhou Shoujun Chen Ming Yan Tianfei Li Mingshou Li LeiWang Zaochang Liu Xinqiao Yu HanweiMei Lijun Luo | 2022 | Molecular Plant2022，15，9： | 3 |
| 7 | Constraints on the depth,geometry and kinematics of blind detachment faults provided by fault-propagation folds:An example from the Mesozoic fold belt of South China显示文摘 | Yan Danping Zhang Bing Zhou Meifu | 2009 | Journal of Structural Geology2009，31，2： | 1 |
| 8 | Geotectonic evolution of lunar LQ-4 region based on multisource data显示文摘The Sinus Iridum region, the first choice for China's 'Lunar Exploration Project' is located at the center of the lunar LQ-4 area and is the site of Chang'e-3(CE-3)'s soft landing. To make the scientific exploration of Chang'e-3 more targeted and scientific, and to obtain a better macro-level understanding of the geotectonic environment of the Sinus Iridum region, the tectonic elements in LQ-4 region have been studied and the typical structures were analyzed statistically using data from CE-1, Clementine, LRO and Lunar Prospector missions. Also, the mineral components and periods of mare basalt activities in the study area have been ascertained. The present study divides the tectonic units and establishes the major tectonic events and sequence of evolution in the study area based on morphology, mineral constituents,and tectonic element distribution. | Jianping Chen Yanbo Xu Xiang Wang Shujun He Danping Yan Shaofeng Liu Yongliao Zou Yongchun Zheng | 2014 | Geoscience Frontiers2014，5，2： | 1 |
| 9 | Detrital zircon record of Neoproterozoic active- margin sedimentation in the eastern Jiangnan Orogen, South China显示文摘 | Wang Wei Zhou Meifu Yan Danping | 2013 | Precambrian Research2013，235，： | 1 |
| 10 | Origin and tectonic significance of a Meso- zoic multi-layer over-thrust system within the Yangtze Block (South China) 显示文摘 | Yan Danping Zhou Meffu Song Honglin Wang Xin- wen Malpas J | 2003 | Tectonophysies2003，361，34： | 1 |
| 11 | Origin and tec- tonic significance of a Mesozoic multi-layer over-thrust system within the Yangtze Block (South China)显示文摘 | Yan Danping Zhou Meifu Song Hongling | 2003 | Tectonophysics2003，361，34： | 1 |
| 12 | Inhibition on Telomerase Activity and Cytotoxic Effects by Cisplatin in Cultured Human Choroidal Melanoma Cells显示文摘Purpose: To study the changes of telomerase activity and cytotoxic effects by Cisplatin;cis-dichlorodiamine platinum (CDDP) in cultured human choroidal melanoma.Material and Methods: The primary cultured human choroidal melanoma cells werecultured in the presence and absence of CDDP with different concentration and timerespectively. The toxic effects were evaluated by MTT and the level of telormarse wasdetected by PCR-ELISA assay. And the relationship between telomerase activity andcytotoxic effects were analyzed by a correlation analysis.Results: Following the increase of the concentration and the time of CDDP, graduallyrepressed telomerase activity was detected in cultured cells. Meanwhile, the restrain rateof the cells increased. The telomerase activity at 24h and 1μg/ml was repressedsignificantly compared with the control cells. However, the appearance of cell deathlagged behind the decreasing of telomerase.Conclusions: CDDP is an effective telomerase inhibitor in cultured choroidal melanomacells of human eyes, which presents concentration and time dependency and can causethe death of cultured cells. | Hao Cheng, Zhongyao Wu, Jianliang Zheng, Guilan Lu, Jianhua Yan Min Liu, Danping Huang, Jianxian LinZhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, China | 2003 | Eye Science2003，19，1： | 1 |
| 13 | Comparing tribological behaviors of sulfur- and phosphorus-free organomolybdenum additive with ZDDP and MoDTC显示文摘 | Lili Yan Wen Yue Chengbiao Wang Danping Wei Bo Xu | 2012 | Tribology International2012，，： | 1 |
| 14 | Enzymatic cascade systems for D-amino acid synthesis:progress and perspectives显示文摘D-amino acids,different from the ubiquitous L-amino acids,are recognized as the“unnatural”amino acids.The applications of D-amino acids have drawn increasing interest from researchers in recent years,and D-amino acids are widely used in various industries,including for food products,pharmaceuticals,and agricultural chemicals.Inspired by the prevalent appli-cations,many synthetic methods for D-amino acids have been developed,which are mainly divided into chemical synthetic methods and biosynthetic methods.Chemical synthesis of D-amino acids has a variety of disadvantages such as multiple reaction steps,low yields,low reaction rates,and difficulties in product extraction.Thus,biosynthetic methods utilizing enzymes are attracting increasing attention because they are more energy-saving and environmentally friendly compared to traditional chemical synthesis.Among all enzymatic methods,multi-enzymatic cascade catalytic methods have significant advantages,such as lower costs,no need for intermediate separation,and higher catalytic efficiency,which is ascribed to the spatial proximity of biocatalysts.In this review,advances in multi-enzyme cascade catalytic systems as well as chemo-enzymatic approaches to synthesize D-amino acids are discussed. | Anwen Fan Jiarui Li Yangqing Yu Danping Zhang Yao Nie Yan Xu | 2021 | Systems Microbiology and Biomanufacturing2021，1，4： | 1 |
| 15 | Origin and tectonic significance of a Mesozoicmulti-layer over-thrust system within the Yangtze Block(South Ghina)显示文摘 | Yan Danping Zhou Meifu Song Honglin Wang Xinwen John Malpas | 2003 | Tectonophysics2003，361，： | 1 |
| 16 | SHRIMP U-Pb zircon geochronological and geochemical evidence for Neoprotero- zoic arc-magmatism along the western margin of the Yangtze Block, South China显示文摘 | Zhou Meifu Yan Danping Kennedy A K | 2002 | Earth and Planetary Science Letters2002，196，： | 1 |
| 17 | Phytosulfokine-α Promotes Root Growth by Repressing Expression of Pectin Methylesterase Inhibitor (PMEI) Genes in Medicago truncatula显示文摘Phytosulfokine-α(PSK-α),a sulfated pentapeptide with the sequence YIYTQ,is encoded by a small precursor gene family in Arabidopsis.PSK-αregulates multiple growth and developmental processes as a novel peptide hormone.Despite its importance,functions of PSK-αin M.truncatula growth remains unknown.In this study,we identified five genes to encode PSK-αprecursors in M.truncatula.All of these precursors possess conserved PSK-αsignature motif.Expression pattern analysis of these MtPSK genes revealed that each gene was expressed in a tissue-specific or ubiquitous pattern and three of them were remarkably expressed in root.Treatment of M.truncatula seedlings with synthetic PSK-αpeptide significantly promoted root elongation.In addition,expression analysis of downstream genes by RNA-seq and qRT-PCR assays suggested that PSK-αsignaling might regulate cell wall structure via PMEI-PME module to promote root cell growth.Taken together,our results shed light on the mechanism by which PSK-αpromotes root growth in M.truncatula,providing a new resource for improvement of root growth in agriculture. | Liangliang Yu Wenjun Zhou Danping Zhang Junhui Yan Li Luo | 2020 | Phyton-International Journal of Experimental Botany2020，89，4： | 1 |
| 18 | SHRIMP U-Pb zricon geochronological and geochemical evidence for Neoproterozoic arc-magmatism along the western margin of the Yangtze Block, South China显示文摘 | Zhou Meifu Yan Danping Kennedy A K | 2002 | Earth and Planetary Science Letters2002，196，12： | 1 |
| 19 | Zricon Lu-Hf isotopic constraints on Neoproterozoic subduction-related crustal growth along the western margin of the Yangtze Block, South China显示文摘 | Zhao Junhong Zhou Meifu Yan Danping | 2008 | Precambrian Research2008，163，34： | 1 |
| 20 | Mesozoic extensional structures of the Fangshan tectonic dome and their subsequent reworking during collisional accretion of the North China Block显示文摘 | Yan Danping | 2006 | Journal of the Geological Society London2006，163，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员