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| 1 | Plasma chitinase 3-like 1 is persistently elevated during first month after minimally invasive colorectal cancer resection显示文摘AIM: To assess blood chitinase 3-like 1(CHi3L1) levels for 2 mo after minimally invasive colorectal resection(MICR) for colorectal cancer(CRC). METHODS: CRC patients in an Institutional Review Board approved data/plasma bank who underwent elective MICR for whom preoperative(PreO p), early postoperative(PostO p), and 1 or more late PostO p samples [postoperative day(POD) 7-27] available were included. Plasma CHi3L1 levels(ng/m L) were determined in duplicate by enzyme linked immunosorbent assay. RESULTS: PreOp and PostOp plasma sample were available for 80 MICR cancer patients for the study. The median PreOp CHi3L1 level was 56.8 CI: 41.9-78.6 ng/mL(n = 80). Significantly elevated(P < 0.001) median plasma levels(ng/mL) over PreOp levels were detected on POD1(667.7 CI: 495.7, 771.7; n = 79), POD 3(132.6 CI: 95.5, 173.7; n = 76), POD7-13(96.4 CI: 67.7, 136.9; n = 62), POD14-20(101.4 CI: 80.7, 287.4; n = 22), and POD 21-27(98.1 CI: 66.8, 137.4; n = 20, P = 0.001). No significant difference in plasma levels were noted on POD27-41. CONCLUSION: Plasma CHi3L1 levels were significantly elevated for one month after MICR. Persistently elevated plasma CHi3L1 may support the growth of residual tumor and metastasis. | HMC Shantha Kumara David Gaita Hiromichi Miyagaki Xiaohong Yan Sonali AC Hearth Linda Njoh Vesna Cekic Richard L Whelan | 2016 | World Journal of Gastrointestinal Oncology2016，8，8： | 4 |
| 2 | Congenital infantile fi- brosarcoma: A masquerader of ulcerated hemangioma显示文摘 | Yan AC Chamlin SL Liang MG | 2006 | Pedi atr Dermatol2006，23，4： | 1 |
| 3 | Cleft lip and palate repair in Hay-Wells/ankyloblepharon-ectodermal dysplasia-clefting syndrome显示文摘 | Cabiling DS Yan AC McDonald-McGinn DM | 2007 | Cleft Palate Craniofac J2007，44，3： | 1 |
| 4 | The CD11/CD18 ( beta2 ) integrins modulate neutrophil caspase activation and survival following TNF-al- pha or endotoxin induced transendothelial migration 显示文摘 | Yan SR Saprn K Lssekutz AC | 2004 | Immunol Cell Biol2004，82，4： | 1 |
| 5 | Phosphorylated interferon-alpha receptor 1 subunit ( IFNaR1 ) acts as a docking site for the latent form of the 113 kDa STAT2 protein 显示文摘 | Yan H Krishnan K Greenlund AC | 1996 | EMBO J1996，15，5： | 1 |
| 6 | Plasma monocyte chemotactic protein-1 remains elevated after minimally invasive colorectal cancer resection显示文摘AIM: To investigate plasma Monocyte Chemotactic Protein-1 levels preoperatively in colorectal cancer(CRC) and benign patients and postoperatively after CRC resection.METHODS: A plasma bank was screened for minimally invasive colorectal cancer resection(MICR) for CRC and benign disease(BEN) patients for whom preoperative, early postoperative, and 1 or more late postoperative samples(postoperative day 7-27) were available. Monocyte chemotactic protein-1(MCP-1) levels(pg/mL) were determined via enzyme linked immuno-absorbent assay. RESULTS: One hundred and two CRC and 86 BEN patients were studied. The CRC patient's median preoperative MCP-1 level(283.1, CI: 256.0, 294.3) was higher than the BEN group level(227.5, CI: 200.2, 245.2; P = 0.0004). Vs CRC preoperative levels, elevated MCP-1 plasma levels were found on postoperative day 1(446.3, CI: 418.0, 520.1), postoperative day 3(342.7, CI: 320.4, 377.4), postoperative day 7-13(326.5, CI: 299.4, 354.1), postoperative day 14-20(361.6, CI: 287.8, 407.9), and postoperative day 21-27(318.1, CI: 287.2, 371.6; P < 0.001 for all). CONCLUSION: Preoperative MCP-1 levels were higher in CRC patients(vs BEN). After MICR for CRC, MCP-1 levels were elevated for 1 mo and may promote angiogenesis, cancer recurrence and metastasis. | HMC Shantha Kumara Elizabeth A Myers Sonali AC Herath Joon Ho Jang Linda Njoh Xiaohong Yan Daniel Kirchoff Vesna Cekic Martin Luchtefeld Richard L Whelan | 2014 | World Journal of Gastrointestinal Oncology2014，6，10： | 1 |
| 7 | Aptamers and aptamer targeted delivery显示文摘 | Yan AC Levy M | 2009 | RNA Biol2009，6，3： | 1 |
| 8 | Pathways contributing to development of spontaneous mammary tumors in BALB/c-Trp53+/-mice显示文摘 | Yan H Blackburn AC Mc Lary SC | 2010 | Am J Pathol2010，176，3： | 1 |
| 9 | 'Urticaria multiforme': a case se- ries and review of acute annular urticarial hypersensitivity syn- dromes in children显示文摘 | Shah KN Honig PJ Yan AC | 2007 | Pediatrics2007，119，5： | 1 |
| 10 | Molecular biolo- gy underlying the clinical heterogeneity of prostate canc- er:an update显示文摘 | Mackinnon AC Yan BC Joseph LJ | 2009 | Arch Pathol Lab Med2009，133，7： | 1 |
| 11 | The safety and efficacy of pimecrolimus, 1%, cream for the treatment of Netherton syndrome: results from an exploratory studv显示文摘 | Yan AC Honig PJ Ming ME | 2010 | Arch Dermatol2010，146，： | 1 |
| 12 | Site of intimal rupture or erosion of thrombosed coronary atheroseclerotic plaques is characterized by an inflammatory process irrespective of the dominant plaque morphology显示文摘 | Yan der Wal AC Becker AE VAN derloos CM | 1994 | Circulation1994，89，： | 1 |
| 13 | Cleft lip and palate repair in Hay-Wells/ankyloblepharon-ectodermal dysplasia-clefting syndrome 显示文摘 | Cabiling DS Yan AC McDonald-McGinn D | 2007 | Cleft Palate Craniofac2007，44，3： | 1 |
| 14 | Association of ACC I polymor- phism in the FSHI3gene with PCOS 显示文摘 | Yan T Wu XL Roy AC | 2000 | Fertil Steril2000，74，5： | 1 |
| 15 | Cleft lip and palate repair in Hay-Wells/ankyloblepharon-ectodennal dysplasia-clefting syndrome显示文摘 | Cabiling DS Yan AC McDonald-McGinn DM | 2007 | Cleft Palate Craniofac J2007，44，： | 1 |
| 16 | Acne update显示文摘 | Smolinski KN Yan AC | 2004 | Curr Opin Pediatr2004，16，： | 1 |
| 17 | Use of interdental distraction osteogenesis for orthodontic tooth alignment and correction of maxillary hypoplasia:A case report显示文摘 | Tong AC Yan BS Chan TC | 2003 | Br J Oral Maxillofac Surg2003，41，3： | 1 |
| 18 | Aquagenic palmoplantar keratoderma显示文摘 | Yan AC Aasi SZ Alms WJ | 2001 | J Am Acad Dermatol2001，44，： | 1 |
| 19 | Pten and p53 converge on c-Myc to control differentiation, self-renewal, and transformation of normal and neoplastic stem cells in glioblastoma 显示文摘 | Zheng H Ying H Yan H Kimmelman AC Hiller D J Chen A J | 2008 | Cold Spring Harb Syrup Quant Biol2008，73，： | 1 |
| 20 | Gamma Ⅲ-crystallin is the primary target of glycation in the bovine lens incubated under physiological conditions 显示文摘 | Yan H Willis AC Harding JJ | 2003 | Biochem J2003，374，3： | 1 |
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