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| 1 | Multispherical interactions and their effects on the Tibetan Plateau's earth system: a review of the recent researches显示文摘The Tibetan Plateau(TP) is a regional Earth system showing very strong interactions among its lithosphere, hydrosphere, cryosphere, biosphere, atmosphere, and anthrosphere. hese interactions manifest TP's impact on surrounding regions and relect TP's response to the global change. Quantifying the multispherical interactions is critically important to understand the TP environment. Our recent years researches including the ongoing program entitled ‘Tibetan Multi-Spheres Interactions and heir Resource-Environment Signiicance(TIMI)', the completed program entitled. ‘Paleo-Altitudes of Tibetan Plateau and Environment(PATE)', as well as the other relating projects have focused on multidisciplinary research approaches and emphasized on three major pathways: Eurasia-Indian plates collision on deep-Earth dynamics, uplit impact on Earth's mantle–crust dynamics, and contemporary interface on land surface and atmospheric dynamics. Our researches have taken in situ measurement as priority and developed several platforms of data acquisition and analysis, including the platforms of water-phase transformations, and ecosystem observations. Our ield investigations have been conducted to obtain data about stratum, paleontology, paleoenvironment, genetic diferentiation of animals and plants. We have developed conceptual and mathematical models for crust uplit formation, paleoclimate, glacial melt,water–air interface lux, vegetation climate, and soil erosion. We have also assessed the anthropogenic impacts on environment. Our researches have achieved new and reliable redating of the mantle–crust interaction and initial formation of the TP, found the interaction between tectonics and uplit of the TP and resultant paleoaltitude acting as a spreading source; discovered the interaction between the westerlies and Indian monsoon acting as a control chain that dominates the TP's contemporary environment. he scientiic results can play fundamental roles in supporting the TP's resource exploration and societal sustainable development. | Tandong Yao Fuyuan Wu Lin Ding Jimin Sun Liping Zhu Shilong Piao Tao Deng Xijun Ni Hongbo Zheng Hua Ouyang | 2015 | National Science Review2015，2，4： | 35 |
| 2 | Glacial distribution and mass balance in the Yarlung Zangbo River and its influence on lakes显示文摘Glaciers in the Yarlung Zangbo River witness severe glacial retreat nowadays,which gives important influence on lake processes in the region.We have studied glacial distribution,glacial mass balance and found large deficit in glacial mass and its impact in the region.Our study also integrated the variation in glacial-fed lakes of the Nam Co and Ranwu Lake,and presented an initial assessment of the impact of glacial mass balance on lakes.The study has shown a significant contribution of glacial melting to recent lake expansion and lake level rising. | YAO TanDong LI ZhiGuo YANG Wei GUO XueJun ZHU LiPing KANG ShiChang WU YanHong YU WuSheng | 2010 | Chinese Science Bulletin2010，55，20： | 34 |
| 3 | Study on the morphology, crystalline structure and thermal properties of yam starch acetates with different degrees of substitution显示文摘This study was carried out to understand and establish the changes in physicochemical properties of starch extracted from Chinese yam (Dioscorea opposita Thunb.) after acetylation. Yam starch acetates with different degrees of substitution (DS) were prepared by the reaction of yam starch with glacial acetic acid/acetic anhydride using sulfuric acid as the catalyst. Their formation was confirmed by the presence of the carbonyl signal around 1750 cm-1 in the Fourier transform infrared (FT-IR) spectra. The thermal behavior of the native starch and starch acetate were investigated using thermogravimetric analysis (TGA) and differential scanning calorimetry (DSC). The results reveal that the starch acetates are more thermally stable than the native starch. The starch esters showed 50% weight loss at tem- peratures from 328℃ to 372 ℃ , while the native starch underwent 50% weight loss at 325℃ . The glass transition temperature (Tg) of the starch decreased from 273℃ to 226℃. The X-ray diffraction (XRD) patterns could be classified as typical of the C-type for yam starch. X-ray diffraction also showed the loss of the ordered C-type starch crystalline structure and the degree of crystallinity of starch de- creased from 36.10% to 10.96% with the increasing DS. The scanning electron microscopy (SEM) sug- gested that the most of the starch granules disintegrated with many visible fragments with the in- creasing DS. | WANG Xu GAO WenYuan ZHANG LiMing XIAO PeiGen YAO LiPing LIU Yi LI KeFeng XIE WeiGuang | 2008 | Science China Chemistry2008，51，9： | 11 |
| 4 | Multi-functional bismuth-doped bioglasses: combining bioactivity and photothermal response for bone tumor treatment and tissue repair显示文摘Treatment of large bone defects derived from bone tumor surgery is typically performed in multiple separate operations,such as hyperthermia to extinguish residual malignant cells or implanting bioactive materials to initiate apatite remineralization for tissue repair;it is very challenging to combine these functions into a material.Herein,we report the first photothermal(PT)effect in bismuth(Bi)-doped glasses.On the basis of this discovery,we have developed a new type of Bi-doped bioactive glass that integrates both functions,thus reducing the number of treatment cycles.We demonstrate that Bi-doped bioglasses(BGs)provide high PT efficiency,potentially facilitating photoinduced hyperthermia and bioactivity to allow bone tissue remineralization.The PT effect of Bi-doped BGs can be effectively controlled by managing radiative and non-radiative processes of the active Bi species by quenching photoluminescence(PL)or depolymerizing glass networks.In vitro studies demonstrate that such glasses are biocompatible to tumor and normal cells and that they can promote osteogenic cell proliferation,differentiation,and mineralization.Upon illumination with near-infrared(NIR)light,the bioglass(BG)can efficiently kill bone tumor cells,as demonstrated via in vitro and in vivo experiments.This indicates excellent potential for the integration of multiple functions within the new materials,which will aid in the development and application of novel biomaterials. | Liping Wang Nicholas J.Long Lihua Li Yao Lu Mei Li Jiangkun Cao Yu Zhang Qinyuan Zhang Shanhui Xu Zhongmin Yang Chuanbin Mao Mingying Peng | 2018 | Light(Science & Applications)2018，7，1： | 6 |
| 5 | Magnesium effects on behavior and substance P mRNA expression in the midbrain of a rat migraine model显示文摘BACKGROUND:Substance P participates in pain transmission and modulation,suggesting a close association with migraine headaches.The clinical application of magnesium has been effective in treating migraines,and the action mechanisms underlying migraines correlate with substance P expression. OBJECTIVE:To analyze different magnesium doses on behavior and substance P mRNA expression in the midbrain of a rat migraine model,and to determine the action pathway of migraine treatment using magnesium. DESIGN,TIME AND SETTING:A completely randomized,controlled,animal experiment was performed at the Experimental Animal Center and Central Laboratory in the Second Hospital of Jilin University between 2007 and 2008. MATERIALS:Magnesium sulfate(25%) was supplied by Tianjin Pharmaceutical Jiaozuo,China. Nitroglycerin was provided by Shanxi Kangbao Biological,China.Substance P primer sequence was synthesized by TaKaRa Biotechnology(Dalian),China. METHODS:A total of 36 healthy,adult,Wistar rats were randomly assigned to 6 groups:control, migraine,low- and high-dose magnesium sulfate treated,and low- and high-dose magnesium sulfate control,with 6 rats in each group.Migraines were induced by subcutaneous injection of 10 mg/kg nitroglycerin in the migraine and low- and high-dose magnesium sulfate treated groups, and 2 mL/kg physiological saline was administered to rats in the control and low- and high-dose of magnesium sulfate control groups.Five minutes following administration,rats in low-dose groups were intraperitoneally injected with 100 mg/kg magnesium sulfate,while those in high-dose groups were injected with 300 mg/kg magnesium sulfate.No interventions were administered to the control and migraine groups. MAIN OUTCOME MEASURES:At 2 hours after nitroglycerin injection,substance P mRNA expression in the rat midbrain was measured by real-time quantitative polymerase chain reaction.At 60-90 minutes after nitroglycerin injection,behavioral changes of pain were analyzed in the experimental rats. RESULTS:The migraine group exhibited significantly lower levels of substance P mRNA expression compared with the control group(P<0.05).Following magnesium sulfate injection,substance P mRNA expression increased,compared with the migraine and control groups(P<0.05).In the low-and high-dose magnesium sulfate treated groups,pain behavior was remarkably ameliorated, compared with the migraine group(P<0.05),particularly with the high-dose injection(P<0.05). CONCLUSION:Magnesium relieved pain behaviors in a rat migraine model in a dose-dependent manner,and the therapeutic effect was achieved in conjunction with increased substance P expression in the midbrain. | Tingmin Yu Gang Yao Liping Zhang | 2009 | Neural Regeneration Research2009，4，11： | 6 |
| 6 | Simulation of texture evolution and deformation mechanism in Mg-3Al-1Zn alloy during uniaxial compression显示文摘The effects of starting texture on he flow curves, and microstructure and texture evolutions of AZ31(Mg-3Al-1Zn-0.3Mn in wt.%) alloy during uniaxial compression at room temperature have been investigated by experiments and simulations. Two kinds of cylindrical compression samples were cut from the AZ31 extruded rod: one was cut with the compression direction parallel to the extruded direction(ED), and the other was cut with the compression axis perpendicular to the ED. The samples were termed as C//ED sample and C⊥ED sample, respectively. The results indicate that the general characteristics of flow curves and texture evolutions in both C⊥ED and C//ED samples during compression can be well explained by the relative activities of deformation mechanisms, which show a strong orientation dependence on the initial textures and the current texture. A significant yield behavior can be induced by {10-12} twinning at the starting deformation, and the lower yield stress in C⊥ED sample can be enhanced by the high activity of basal slip. The work hardening behavior is related to the activities of basal slip, pyramidal slip, {10-12} twinning, as well as {10-11} twinning. However, the activity of prismatic slip is insensitive to the starting texture, and mostly negligible in all samples. | YAO JinYi WANG BingShu DENG LiPing CHAPUIS Adrien LI Qiang LIU Qing | 2015 | Science China(Technological Sciences)2015，58，12： | 4 |
| 7 | Enhancement of transfection efficiency for HeLa cells via incorporating arginine moiety into chitosan显示文摘Arginine-rich peptides have attracted considerable attention due to their distinct internalization mechanism. It was reported that arginine and guanidino moieties were able to translocate through cell membranes and played a critical role in the process of membrane permeation. In this work, arginine was conjugated to the backbone of chitosan to form a novel chitosan derivative, arginine modified chitosan (Arg-CS). Arg-CS/DNA complexes were prepared according to the method of coacervation process. The physicochemical properties of Arg-CS and Arg-CS/DNA complexes were characterized and the transfection activity and efficiency mediated by Arg-CS/DNA complexes were investigated taking HeLa cells as target cells. Arg-CS was characterized by FTIR and 13C NMR. Arg-CS/DNA polye- lectrolyte complexes were investigated by agarose gel retardation, dynamic light scattering (DLS) and atomic force microscopy (AFM). The results revealed that the Arg-CS/DNA complexes started to form at N/P ratio of 2:1, and the size of particles varied from 100 to 180 nm. The cytotoxicity of Arg-CS and their complexes with plasmid DNA were determined by MTT assay for HeLa cells, and the results suggested that Arg-CS/DNA complexes were slightly less toxic than Arg-CS. Moreover, the derivative alone and their complexes showed significantly lower toxicity than PEI and PEI/DNA complexes, respectively. Taking HeLa cells as target cells and using pGL3-control as reporter gene, the luciferase expression mediated by Arg-CS was greatly enhanced to about 100 folds compared with the luciferase expression mediated by chitosan at different pH media. These results suggest that Arg-CS is a promising candi- date as a safe and efficient vector for gene delivery and transfection. | ZHU DunWan ZHANG HaiLing BAI JinGen LIU WenGuang LENG XiGang SONG CunXian YANG Jian LI XiaoWei JIN Xu SONG LiPing LIU LanXia LI XiuLan ZHANG Yang YAO KangDe | 2007 | Chinese Science Bulletin2007，52，23： | 4 |
| 8 | Pm67, a new powdery mildew resistance gene transferred from Dasypyrum villosum chromosome 1V to common wheat(Triticum aestivum L.)显示文摘Powdery mildew, caused by the biotrophic fungus Blumeria graminis f. sp. tritici(Bgt), is a global disease that poses a serious threat to wheat production. To explore additional resistance gene, a wheatDasypyrum villosum 1 V#5(1 D) disomic substitution line NAU1813(2 n = 42) with high level of seedling resistance to powdery mildew was used to generate the recombination between chromosomes 1 V#5 and1 D. Four introgression lines, including t1 VS#5 ditelosomic addition line NAU1815, t1 VL#5 ditelosomic addition line NAU1816, homozygous T1 DL·1 VS#5 translocation line NAU1817, and homozygous T1 DS·1 VL#5 translocation line NAU1818 were developed from the selfing progenies of 1 V#5 and 1 D double monosomic line that derived from F1 hybrids of NAU1813/NAU0686. All of them were characterized by fluorescence in situ hybridization, genomic in situ hybridization, 1 V-specific markers analysis, and powdery mildew tests at different developmental stages. A new powdery mildew resistance gene named Pm67 was physically located in the terminal bin(FL 0.70–1.00) of 1 VS#5. Lines with Pm67 exhibited seedling stage immunity and tissue-differentiated reactions at adult plant stage. The sheaths, stems, and spikes of the Pm67 line were still immune, but the leaves showed a low degree of susceptibility.Microscopic observation showed that most penetration attempts were stopped in association with papillae on the sheath, and colonies cannot form conidia on the susceptible leaf of Pm67 line at adult plant stage, suggesting that the defence layers of the Pm67 line is tissue-differentiated. Thus, the T1 DL·1 VS#5 translocation line NAU1817 provides a new germplasm in wheat breeding for improvement of powdery mildew resistance. | Ruiqi Zhang Chuanxi Xiong Huanqing Mu Ruonan Yao Xiangru Meng Lingna Kong Liping Xing Jizhong Wu Yigao Feng Aizhong Cao | 2021 | The Crop Journal2021，9，4： | 3 |
| 9 | An Efficient Method of Noroviruses Recovery from Oysters and Clams显示文摘Noroviruses (NoVs) are widespread causes of nonbacterial gastroenteritis. Outbreaks of NoVs caused diseases are commonly ascribed to the consumption of contaminated shellfish. The concentration and RNA extraction of NoVs are crucial steps of detecting NoVs in shellfish. This study aimed to select a simple, rapid and highly efficient recovery method of NoVs detection with real-time RT-PCR. Four methods of recovering GI.3 and GII.4 NoVs from spiked digestive tissues of oysters and clams, respectively, were compared, of them, the method involving proteinase K and PEG 8000 was found the most efficient. With this method, 9.3% and 13.1% of GI.3 and GII.4 NoVs were recovered from oysters and 9.6% and 12.3% of GI.3 and GII.4 NoVs were recovered from clams, respectively. This method was further used to detect NoVs in 84 oysters (Crassostrea gigas) and 86 clams (Ruditapes philippinarum) collected from 10 coastal cities in China from Jan. 2011 to Feb. 2012. The NoVs isolation rates were 10.47% of clams (9/86) and 7.14% of oysters (6/84). All the detected NoVs belonged to genotype GII. The NoVs recovery method selected is efficient for NoVs detection in oysters and clams. | ZHOU Deqing MA Liping ZHAO Feng YAO Lin SU Laijin LI Xinguang | 2013 | Journal of Ocean University of China2013，12，1： | 3 |
| 10 | Association of systemic inflammation and body mass index with survival in patients with resectable gastric or gastroesophageal junction adenocarcinomas显示文摘Objective:The systemic inflammation index and body mass index(BMI)are easily accessible markers that can predict mortality.However,the prognostic value of the combined use of these two markers remains unclear.The goal of this study was therefore to evaluate the association of these markers with outcomes based on a large cohort of patients with gastric cancer.Methods:A total of 2,542 consecutive patients undergoing radical surgery for gastric or gastroesophageal junction adenocarcinoma between 2009 and 2014 were included.Systemic inflammation was quantified by the preoperative neutrophil-to-lymphocyte ratio(NLR).High systemic inflammation was defined as NLR≥3,and underweight was defined as BMI<18.5 kg/m2.Results:Among 2,542 patients,NLR≥3 and underweight were common[627(25%)and 349(14%),respectively].In the entire cohort,NLR≥3 or underweight independently predicted overall survival(OS)[hazard ratio(HR):1.236,95%confidence interval(95%CI):1.069–1.430;and HR:1.600,95%CI:1.350–1.897,respectively]and recurrence-free survival(RFS)(HR:1.230,95%CI:1.054–1.434;and HR:1.658,95%CI:1.389–1.979,respectively).Patients with both NLR≥3 and underweight(vs.neither)had much worse OS(HR:2.445,95%CI:1.853–3.225)and RFS(HR:2.405,95%CI:1.802–3.209).Furthermore,we observed similar results in subgroup analyses according to pathological stage,age,and postoperative chemotherapy.Conclusions:Our results showed that preoperative elevated NLR and decreased BMI had a significant negative effect on survival.Underweight combined with severe inflammation could enhance prognostication.Taking active therapeutic measures to reduce inflammation and increase nutrition may help improve outcomes. | Xianchun Gao Yanan Pan Weili Han Caie Hu Chenchen Wang Ling Chen Yong Guo Yupeng Shi Yan Pan Huahong Xie Liping Yao Jianjun Yang Jianyong Zheng Xiaohua Li Xiaonan Liu Liu Hong Jipeng Li Mengbin Li Gang Ji Zengshan Li Jielai Xia Qingchuan Zhao Daiming Fan Kaichun Wu Yongzhan Nie | 2021 | Cancer Biology & Medicine2021，18，1： | 2 |
| 11 | Downregulation of thioredoxin reductase 1 expression in the substantia nigra pars compacta of Parkinson's disease mice显示文摘Because neurons are susceptible to oxidative damage and thioredoxin reductase 1 is extensively distributed in the central nervous system and has antioxidant properties,we speculated that the enzyme may be involved in the pathogenesis of Parkinson’s disease.A Parkinson’s disease model was produced by intraperitoneal injection of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine into C57BL/6 mice.Real-time reverse transcription-PCR,western blot analysis and colorimetric assay showed that the levels of thioredoxin reductase 1 mRNA and protein were decreased,along with a significant reduction in thioredoxin reductase activity,in the midbrain of Parkinson’s disease mice compared with normal mice.Immunohistochemical staining revealed that the number of thioredoxin reductase 1-positive neurons in the substantia nigra pars compacta of Parkinson’s disease mice was significantly decreased compared with normal mice.These experimental findings suggest that the expression of thioredoxin reductase 1 in the substantia nigra pars compacta of Parkinson’s disease mice is significantly decreased,and that the enzyme may be associated with disease onset. | Zihua Liu Yuhong Jing Jie Yin Jiying Mu Tingting Yao Liping Gao | 2013 | Neural Regeneration Research2013，8，35： | 2 |
| 12 | Postzygotic single-nucleotide mosaicisms in whole-genome sequences of clinically unremarkable individuals显示文摘 | August Y Huang Xiaojing Xu Adam Y Ye Qixi Wu Linlin Yan Boxun Zhao Xiaoxu Yang Yao He Sheng Wang Zheng Zhang Bowen Gu Han-Qing Zhao Meng Wang Hua Gao Ge Gao Zhichao Zhang Xiaoling Yang Xiru Wu Yuehua Zhang Liping Wei | 2014 | Cell Research2014，24，11： | 2 |
| 13 | Absence of hexavalent chromium in marine carbonates:implications for chromium isotopes as paleoenvironment proxy显示文摘The oxygenation of Earth’s atmosphere is widely regarded to have played an important role in early-life evolution.Chromium(Cr)isotopes recorded in sedimentary rocks have been used to constrain the atmospheric oxygen level(AOL)over geological times based on the fact that a positive Cr isotopic signature is linked to the presence of Cr(Ⅵ)as a result of oxidative continental weathering.However,there is no direct evidence of the presence of Cr(Ⅵ)in sedimentary rocks yet.Carbonates are most widely distributed over geological times and were thought to have incorporated Cr(Ⅵ)directly from seawater.Here,we present results of Cr valence states in carbonates which show Cr(Ⅲ)is the dominant species in all samples spanning a wide range of geological times.These findings indicate that Cr(Ⅵ)in seawater was reduced either before or after carbonate precipitation,which might have caused Cr isotopic fractionation between seawater and carbonates,or marine carbonates preferentially uptake Cr(Ⅲ)from seawater.As Cr(Ⅲ)can come from non-redox Cr cycling,which also can cause isotopic fractionation,we suggest that positively fractionated Cr isotopic values do not necessarily correspond to the rise in AOL. | Ziyao Fang Liping Qin Wei Liu Tao Yao Xiaoyan Chen Shiqiang Wei | 2021 | National Science Review2021，8，3： | 2 |
| 14 | A preliminary study on numerical simulation of microwave heating process for chemical reaction and discussion of hotspot and thermal runaway phenomenon显示文摘The nonlinear process of microwave heating chemical reaction is studied by means of numerical simulation. Especially,the variation of temperature in terms of space and time,as well as the hotspot and thermal runaway phenomena are discussed. Suppose the heated object is a cylinder and the incident electromagnetic(EM) wave is plane wave,the problem turns out to be a coupling calculation of 2D multi-physical fields. The integral equation of EM field is solved using the method of moment(MoM) and the thermal conduction equation is solved using a semi-analysis method. Moreover,a method to determine the equivalent complex permittivity of reactant under the heating is presented in order to perform the calculation. The numerical results for water and a dummy chemical reaction(A) show that the hotspot is a ubiquitous phenomenon in microwave heating process. When the radius of the heated object is small,the highest temperature occurs somewhere inside the object due to the concentration of the EM wave. While the radius increases to a certain degree,the highest temperature occurs somewhere close to the surface due to the skin effect,and the whole high temperature area shows crescent-shaped. That is in accordance with basic physical principles. If the radius is kept the same in the heating process,the hotspot position of water does not change,while that of reaction A with several radius values varies. For either water or A,the thermal runaway phenomenon in which small difference of radius results in large difference of highest temperature,occurs easily when the radius is small. On the contrary,it is not evident when the radius is large. Moreover,it is notable that the highest temperature in water shows oscillating decreasing trend with the increase of radius,but in reaction A almost decreases monotonously. Further study should be performed to determine if this difference is only an occasional occurrence. | ZHAO Xiang HUANG KaMa YAN LiPing YAO Yuan | 2009 | Science China(Physics,Mechanics & Astronomy)2009，52，4： | 2 |
| 15 | Running Accuracy Analysis of a 3-RRR Parallel Kinematic Machine Considering the Deformations of the Links显示文摘Parallel kinematic machines have drawn considerable attention and have been widely used in some special fields.However,high precision is still one of the challenges when they are used for advanced machine tools.One of the main reasons is that the kinematic chains of parallel kinematic machines are composed of elongated links that can easily suffer deformations,especially at high speeds and under heavy loads.A 3-RRR parallel kinematic machine is taken as a study object for investigating its accuracy with the consideration of the deformations of its links during the motion process.Based on the dynamic model constructed by the Newton-Euler method,all the inertia loads and constraint forces of the links are computed and their deformations are derived.Then the kinematic errors of the machine are derived with the consideration of the deformations of the links.Through further derivation,the accuracy of the machine is given in a simple explicit expression,which will be helpful to increase the calculating speed.The accuracy of this machine when following a selected circle path is simulated.The influences of magnitude of the maximum acceleration and external loads on the running accuracy of the machine are investigated.The results show that the external loads will deteriorate the accuracy of the machine tremendously when their direction coincides with the direction of the worst stiffness of the machine.The proposed method provides a solution for predicting the running accuracy of the parallel kinematic machines and can also be used in their design optimization as well as selection of suitable running parameters. | WANG Liping JIANG Yao LI Tiemin | 2014 | Chinese Journal of Mechanical Engineering2014，27，5： | 2 |
| 16 | Controllable generation of large-scale highly regular gratings on Si films显示文摘The application of femtosecond laser-induced periodic surface texturing has significant potential in medicine,optics,tribology,and biology,among other areas.However,when irradiated by a large intense laser spot,the periodic structures usually exhibit an uncontrollable regularity,forming bifurcated patterns,thus limiting their widespread application.Irregularity originates from numerous independent branching seeds.The usual solution to this problem is to utilize the quasi-direct laser writing technique,that is,by limiting the laser beam size(diameter of<10 wavelengths)and scanning the beam or samples using 2D translation stages.Herein,we demonstrate an optical localization-induced nonlinear competition mechanism to solve this problem,which occurs at a fluence nearly one order of magnitude below the ablation threshold.Owing to the low intrinsic absorption of silicon and ultralow applied fluence,this mechanism ensures the self-selection of a single seed to initiate an array of bifurcated-free gratings under stationary irradiation with a large laser spot(diameter>100 wavelengths).Surprisingly,some unconventional complex patterns,such as radial,annular,and spiral gratings,can also be easily produced by structured light fields with unprecedented regularity.Their diameters reach up to>500μm.Moreover,we can artificially control the initial seeding structure to further improve the regularity of the gratings,defined by dispersion in the ripple orientation angle in their 2D Fourier transform.As a result,the regularity in our experiments produced by a large laser spot is even higher than that scanned by a tiny beam.Controllable and highly regular ripples are beneficial to the structural coloring effects because they arise from the light diffraction by subwavelength gratings. | Jiao Geng Xiaoguo Fang Lei Zhang Guangnan Yao Liye Xu Fengjiang Liu Weiwei Tang Liping Shi Min Qiu | 2021 | Light(Advanced Manufacturing)2021，2，3： | 2 |
| 17 | In situ instant generation of an ultrabroadband near-infrared emission center in bismuth-doped borosilicate glasses via a femtosecond laser显示文摘Bismuth(Bi)-doped photonic materials, which exhibit broadband near-infrared(NIR) luminescence(1000–1600 nm), are evolving into interesting gain media. However, the traditional methods have shown their limitations in enhancing Bi NIR emission, especially in the microregion. Consequently, the typical NIR emission has seldom been achieved in Bi-doped waveguides, which highly restricts the application of Bi-activated materials.Here, superbroadband Bi NIR emission is induced in situ instantly in the grating region by a femtosecond(fs)laser inside borosilicate glasses. A series of structural and spectroscopic characterizations are summoned to probe the generation mechanism. And we show how this novel NIR emission in the grating region can be enhanced significantly and erased reversibly. Furthermore, we successfully demonstrate Bi-activated optical waveguides.These results present new insights into Bi-doped materials and push the development of broadband waveguide amplification. | LIPING WANG JIANGKUN CAO YAO LU XIAOMAN LI SHANHUI XU QINYUAN ZHANG ZHONGMIN YANG MINGYING PENG | 2019 | Photonics Research2019，7，3： | 2 |
| 18 | Research Progress of Rice-Fish Integrated Farming显示文摘Rice-fish integrated farming( RFIF) can change the agricultural production pattern from mono-farming model to the co-farming model,and the stereoscopic and integrated farming system established by RFIF can change the flat production to the stereoscopic production. Therefore,RFIF is the important development direction for agriculture to change pattern and adjust structure. In order to further promote development of the research and application of RFIF,the general development situation of RFIF in China was reviewed; the effects of RFIF on increasing farmer' income and enhancing agricultural efficiency were clarified. The technologies matched with RFIF,such as rice paddy engineering technology,safe plant protection technology,security fertilization technology,fish disease prevention and control technology and water quality management technology,were summarized,and the supporting role of RFIF for agriculture was pointed out. In addition,the development prospect of RFIF was proposed,as well as the key research direction of RFIF. | Shunlong MENG Gengdong HU DANDan LI Liping QIU Chao SONG Limin FAN Yao ZHENG Wei WU Jiazhang CHEN Xuwen BING | 2018 | Agricultural Biotechnology2018，7，4： | 2 |
| 19 | Effect of CuO or/and V 2 O 5 oxide additives on Bi 2 O 3 –ZnO–Ta 2 O 5 based ceramics显示文摘 | Bo Shen Xi Yao Liping Kang Dengshan Peng | 2004 | Ceramics International2004，，7： | 1 |
| 20 | Comparison of hepatic gene expression profiles between three mouse models of Nonalcoholic Fatty Liver Disease显示文摘Non-alcoholic fatty liver disease (NAFLD) has become the most common chronic liver disorder worldwide. Murine models of NAFLD have been widely used to explore its pathogenesis. In this study, we performed a systematic evaluation of hepatic genome-wide mRNA expression by RNA-Sequencing using three mouse models of NAFLD: leptin receptor deficient db/db mice, high-fat high-sugar diet (HSHF)-induced obese mice, and dexamethasone (DEX)-induced NAFLD mice. As a result, we found both distinct and common pathways in the regulation of lipid metabolism from transcriptomes of three mouse models. Moreover, only a total of 12 differentially expressed genes (DEGs) were commonly detected among all three mouse groups, indicating very little overlap among all three models. Therefore, our results suggest that NAFLD is a heterogeneous disease with highly variable molecular mechanisms. | Liping Xiang Yang Jiao Yiling Qian Yao Li Fei Mao Yan Lu | 2022 | Genes & Diseases2022，9，1： | 1 |
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