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| 1 | Functional Variant in microRNA-196a2 Contributes to the Susceptibility of Congenital Heart Disease in a Chinese Population显示文摘 | XU , J. Hu, Z.B. Xu, Z.F. Gu, H.Y Yi, L. Cao, H. L. Chen, J. P. Tian, T. Liang, J. Lin, Y. Qiu, W. S. Ma, H.X. Shen, H. B Chen, Y. J. | 2009 | 南京医科大学学报(自然科学版)2009，29，11： | 20 |
| 2 | STUDY ON THE HOT DEFORMATION BEHAVIORS OF Al-Zn-Mg-Cu-Cr ALUMINUM ALLOY显示文摘Al-Zn-Mg-Cu-Cr 铝合金的热变丑行为和 mierostructures 用热模拟测试,光显微镜学和传播电子显微镜学被学习了。作为结果,在各种各样的变丑条件下面的真压力对真紧张曲线和微观结构被获得。微观结构逐渐地倾向与升起的变丑温度和与变丑温度的减少或与提起紧张率精制的再结晶谷物动态再结晶。在在随后的热处理的 Zener-HoUomon 参数(Z) 和平均再结晶谷物尺寸之间的量的关系被建立。 | G. Y. Lin Z.F. Zhang H. Zhang D.S. Peng J. Zhou | 2008 | Acta Metallurgica Sinica(English Letters)2008，21，2： | 19 |
| 3 | Cesarean scar pregnancy: issues in management显示文摘 | K.‐M.Seow L.‐W.Huang Y.‐H.Lin M.Yan‐Sheng Lin Y.‐L.Tsai J.‐L.Hwang | 2004 | Ultrasound Obstet Gynecol2004，，3： | 12 |
| 4 | BubR1 phosphorylates CENP-E as a switch enabling the transition from lateral association to end-on capture of spindle microtubules显示文摘Error-free mitosis depends on accurate chromosome attachment to spindle microtubules, powered congression of those chromosomes, their segregation in anaphase, and assembly of a spindle midzone at mitotic exit. The centromere-associated kinesin motor CENP-E, whose binding partner is BubR1, has been implicated in congression of misaligned chromosomes and the transition from lateral kinetochore-microtubule association to end-on capture. Although previously proposed to be a pseudokinase, here we report the structure of the kinase domain of Drosophila melanogaster BubR1, revealing its folding into a conformation predicted to be catalytically active. BubR1 is shown to be a bona fide kinase whose phosphorylation of CENP-E switches it from a laterally attached microtubule motor to a plus-end microtubule tip tracker. Computational modeling is used to identify bubristatin as a selective BubR1 kinase antagonist that targets the αN1 helix of N-terminal extension and αC helix of the BubR1 kinase domain. Inhibition of CENP-E phosphorylation is shown to prevent proper microtubule capture at kinetochores and, surprisingly, proper assembly of the central spindle at mitotic exit. Thus, BubR1-mediated CENP-E phosphorylation produces a temporal switch that enables transition from lateral to end-on microtubule capture and organization of microtubules into stable midzone arrays. | Yuejia Huang Lin Lin Xing Liu Sheng Ye Phil Y. Yao Wenwen Wang Fengrui Yang Xinjiao Gao Junying Li Yin Zhang Jiancun Zhang Zhihong Yang Xu Liu Zhenye Yang Jianye Zang Maikun Teng Zhiyong Wang Ke Ruan Xia Ding Lin Li Don W. Cleveland Rongguang Zhang Xuebiao Yao | 2019 | Cell Research2019，29，7： | 8 |
| 5 | A Feasibility Study of FES Restoration of Elbow Movementsfor C5/C6 Quadriplegic Patients显示文摘This paper presents a feasibility study of restoration of elbow movements in C5/C6quadriplegic patientS by functional electrical stimulation (FES). A biomechanical model of thebiceps and triceps muscles and elbow joint is developed for computer simulation. A feedbackcontrol method is evaluated in the study for the static and dynamic responses. Results indicate thatit is possible to achieve extension control at the elbow joint with electrical stimulation of extensormuscle. These results may provide a plausible control method for controlling elbow extensionmovements in clinical application. | N. Lan J.C. Wang P. Lin and Y. Li(Dept. of Electrical Engineering, Tsinghua UniversityBeijing 100084, P. R. China)(Spinal Cord injury Unit, Charity HospitalChina Rehabilitation Research Center, Beijing 100077, P. R. China) | 1998 | Chinese Journal of Biomedical Engineering(English Edition)1998，7，3： | 6 |
| 6 | A Prospective Randomized Trial Comparing Percutaneous Local Ablative Therapy and Partial Hepatectomy for Small Hepatocellular Carcinoma显示文摘 | Min-Shan Chen Jin-Qing Li Yun Zheng Rong-Ping Guo Hui-Hong Liang Ya-Qi Zhang Xiao-Jun Lin Wan Y. Lau | 2006 | Annals of Surgery2006，，3： | 5 |
| 7 | Engaging HIV-infected patients in antiretroviral therapy services: CD4 cell count testing after HIV diagnosis from 2005 to 2009 in Yunnan and Guangxi, China显示文摘中国的国家免费 antiretroviral 治疗节目的开始和扩大导致了的背景在它的参加者之中的幸存的重要改进。在加强 HIV 屏蔽和照顾的有效连接之上的在治疗范围休息上面的进一步的可伸缩的成功。及时 CD4 房间计数在 HIV 诊断以后测试是必要的决定一个病人是否为 antiretroviral 治疗满足标准,并且代表一个关键连接使 感染HIV 的病人参加适当照顾,它没在 China.Methods 被评估我们评估了所有病人 16 年在云南和 Guangxi.Multivariate 逻辑回归模型测试了从 2005~2009 积极的 HIV 的人,被使用房间计数在 H 以后在 6 个月以内测试识别与 CD4 的缺乏联系的因素在学习经期上, 30 (37%) 635 在 6 月收到 HIV 诊断以内题目收到了一个 CD4 房间计数。CD4 房间计数在 6 月 HIV 诊断以内测试的率在 2009 在 2005 ~ 62% 从 7% 显著地增加了。除 HIV 诊断的更早的年以外,为 CD4 房间计数在 multivariate 分析测试的否定预言者包括了老年,没结婚或不清楚的婚姻地位,下狱,在性播送疾病诊所的诊断,作为与人性交的人分类的 HIV 传播的模式,静脉内的药用户或传播线路不清楚少数种族,高中或高等教育的收据,在自愿的建议,并且有 HIV 的诊断和严峻的诊所积极 pa 然而, HIV 积极病人的一个相当大的比例仍然在 6 月诊断以内缺乏 CD4testing。特别地在有识别风险因素的病人之中,测试的改善 CD4 是必要的与艺术服务连接病人并且优化治疗范围。 | ZHANG Yao LU Lin LI Hui-qin LIU Wei TANG Zhi-rong FANG Hua Jennifer Y. Chen MA Ye ZHAO Yan Ray Y. Chen ZHANG Fu-jie | 2011 | Chinese Medical Journal2011，，10： | 5 |
| 8 | Phytogenic Feed Additive for Sows: Effects on Sow Feed Intake, Serum Metabolite Concentrations, IgG Level, Lysozyme Activity and Milk Quality显示文摘 | M. Zhong D. Wu Y. Lin Z. F. Fang | 2011 | Journal of Agricultural Science and Technology(A)2011，1，6： | 4 |
| 9 | 双极主观等级量表的级别选取显示文摘双极等级工具(Bipolar rating instruments)用来测量人们对产品的情感观点。这种方法的常用和典型代表就是分为5,7和9这三种等级级别的等级量表(RatingScales),其中的数字代表了等级级别的数目(例如,‘5’表示总共有5种等级级别)。然而到目前很少有文献关注等级量表的最佳的级别数目问题。这里对这一问题进行了初步研究,尤其是针对这样的三种等级量表(S5,S7,S9),通过实验来给出了答案;研究表明,由于其高可靠性S最为适合。 | 乔柱 杨国盛 Amol Ghorpade Y. Lin 章文俊 | 2009 | 机械设计与研究2009，25，4： | 4 |
| 10 | Two Human ACAT2 mRNA Variants Produced by Alternative Splicing and Coding for Novel Isoenzymes显示文摘酰辅酶 A:cholesterol 酰基转移酶(ACAT2 ) 2 在胆固醇吸收起一个重要作用。人的 ACAT2 高度在小肠和胎儿的肝被表示,但是它的表示极大地在成年的肝被减少。全身的人的 ACAT2 信使 rna 编码蛋白质,指明的 ACAT2a,与 522 氨基酸。我们以前在肠的 Caco-2 房间报导了人的 ACAT2 基因和区别依赖者倡导者活动的组织。在当前的工作,其他的拼接生产的二人的 ACAT2 信使 rna 变体分别地被克隆并且预言了编码二新奇 ACAT2 isoforms,命名 ACAT2b 和 ACAT2c,与 502 和 379 氨基酸。这些信使 rna 变体在 4 上由前的缺乏不同于 ACAT2a 信使 rna (ACAT2b 信使 rna ) 并且加 8-9-10 (ACAT2c 信使 rna ) 的前 ons 4-5。显著地,或者拼接的 ACAT2 信使 rna 变体的可比较的数量被 RT-PCR 检测,并且西方的污点分析在人的肝和肠房间证实了他们的相应蛋白质的存在。而且,磷酸化和酶的活动分析证明新奇 isoenzymes ACAT2b 和 ACAT2c 缺乏 phosphorylatable 地点 SLLD,和他们归结为 ACAT2a 的 25%-35% 的酶的活动。这些证据显示拼接的那种选择生产编码新奇 ACAT2 isoenzymes 的二人的 ACAT2 信使 rna 变体。我们的调查结果可能帮助在某些生理、病理学的条件下面理解 ACAT2 基因表示的规定。 | Xiao-Min YAO Can-Hua WANG Bao-Liang SONG Xin-Ying YANG Zhen-Zhen WANG Wei QI Zhi-Xin LIN Catherine C. Y. CHANG Ta-Yuan CHANG Bo-Liang LI | 2005 | Acta Biochimica et Biophysica Sinica2005，37，12： | 3 |
| 11 | Estimating treatment effects in observational studies显示文摘 | Julia Y. LIN Ying LU | 2011 | 上海精神医学2011，23，6： | 3 |
| 12 | Cirrhotic patients at increased risk of peptic ulcer bleeding: a nationwide population‐based cohort study显示文摘 | J.‐C. Luo H.‐B. Leu M.‐C. Hou C.‐C. Huang H.‐C. Lin F.‐Y. Lee F.‐Y. Chang W.‐L. Chan S.‐J. Lin J.‐W. Chen | 2012 | Aliment Pharmacol Ther2012，，6： | 3 |
| 13 | Short term soil priming effects and the mineralisation of biochar following its incorporation to soils of different pH显示文摘 | Y. Luo M. Durenkamp M. De Nobili Q. Lin P.C. Brookes | 2011 | Soil Biology and Biochemistry2011，，11： | 3 |
| 14 | Interferon‐based therapy reduces risk of stroke in chronic hepatitis C patients: a population‐based cohort study in Taiwan显示文摘 | C.‐S. Hsu J.‐H. Kao Y.‐C. Chao H. H. Lin Y.‐C. Fan C.‐J. Huang P.‐S. Tsai | 2013 | Aliment Pharmacol Ther2013，，4： | 3 |
| 15 | Finite element analysis of stress intensity factors for cracks at a bi-material interface显示文摘 | K. Y. Lin J. W. Mar | 1976 | International Journal of Fracture1976，，4： | 2 |
| 16 | 建立临床试验的数据监测委员会(英文)显示文摘数据监测委员会是由研究赞助者指定的一组临床医生和生物统计学家,对临床试验的安全性、科学有效性和完整性进行独立评估。在美国,食品和药物管理局要求在评估所有新的干预时在要成立数据监测委员会。在其他临床研究中,如果存在重大的安全问题、实施双盲治疗分配或者预期对临床实践会产生重大影响,也强烈建议成立数据监测委员会。因为数据监测委员会对经常参加此类研究的弱势群体提供了一层额外的保护,所以他们在精神病学临床研究中是非常重要的。本报告描述了数据监测委员会的作用,组建和运作。 | Julia Y. LIN Ying LU | 2014 | 上海精神医学2014，26，1： | 2 |
| 17 | Cancer Incidence Trends Among Asian American Populations in the United States, 1990–2008显示文摘 | Scarlett Lin Gomez Anne-Michelle Noone Daphne Y. Lichtensztajn Steve Scoppa James T. Gibson Lihua Liu Cyllene Morris Sandy Kwong Kari Fish Lynne R. Wilkens Marc T. Goodman Dennis Deapen Barry A. Miller | 2013 | JNCI Journal of the National Cancer Institute2013，，15： | 2 |
| 18 | Detection of Hypermethylated Vimentin in Urine of Patients with Colorectal Cancer显示文摘 | Benjamin P. Song Surbhi Jain Selena Y. Lin Quan Chen Timothy M. Block Wei Song Dean E. Brenner Ying-Hsiu Su | 2012 | The Journal of Molecular Diagnostics2012，，2： | 2 |
| 19 | Radiation-induced liver disease after three-dimensional conformal radiotherapy for patients with hepatocellular carcinoma: dosimetric analysis and implication显示文摘 | Jason Chia-Hsien Cheng Jian-Kuen Wu Chao-Ming Huang Hua-Shan Liu David Y. Huang Skye Hongiun Cheng Stella Y. Tsai James Jer-Min Jian Yu-Mong Lin Tsun-I Cheng Cheng-Fang Horng Andrew T. Huang | 2002 | International Journal of Radiation Oncology, Biology, Physics2002，，： | 2 |
| 20 | MLCROSTRUCTURE AND PROPERTIES OF C-Cu NANOSTRUCTURE THIN FILM显示文摘Nanostructured C-Cu thin films were deposited by reactive sputtering method and cosputtering method. The relationships between microstructures, properties, and deposition parameters were studied and the results obtained from TEM, AFM, and XPS. indicate that the thin films are nanostructural, and have good in-depth uniformity. The selected area electron diffraction (SAED) found that the nanosize Cu particles have the fcc structure and the others are amorphous carbon or nanocrystallized graphitic carbon. The peak positions of the Cu and C in XPS indicate them to be at the elemental state. In the JR transmission spectrum, diamond two-phonon absorption and graphite Reman peaks were observed, which suggests microcrystal diamond particles and graphite components exrist in the C-Cu film. The higher electrical resistivity was obtained. | Y.N. Sun, K.X. Zhang, X. Gao, D. Q. Yang, Z.D. Lin and Y. Guo Lauzhou Institute of Physics, P.O. Box 94, Lanzhou 730000, China | 2002 | Acta Metallurgica Sinica(English Letters)2002，15，2： | 2 |
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