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| 1 | Homology-mediated end joining-based targeted integration using CRISPR/Cas9显示文摘 | Yao, Xuan Wang, Xing Hu, Xinde Liu, Zhen Liu, Junlai Zhou, Haibo Shen, Xiaowen Wei, Yu Huang, Zijian Ying, Wenqin Wang, Yan Nie, Yan-Hong Zhang, Chen-Chen Li, Sanlan Cheng, Leping Wang, Qifang Wu, Yan Huang, Pengyu Sun, Qiang Shi, Linyu Yang, Hui | 2017 | Cell Research2017，27，6： | 28 |
| 2 | One-step generation of complete gene knockout mice and monkeys by CRISPR/Cas9-mediated gene editing with multiple sgRNAs显示文摘CRISPR/Cas9 系统是一个有效编辑基因的方法,但是编辑基因的动物的多数显示出 mosaicism,与编辑仅仅在房间的部分发生。这里,我们证明那单个基因或多重基因能被 Cas9 mRNA 和多重邻近的单个指南的 RNA 的 zygotic 注射完全在老鼠和猴子胚胎击倒(spaced 10-200 bp 分开) 指向仅仅一把单个钥匙每基因的 exon。个别地在 Y 染色体上跟随八基因的指向的删除的 F0 老鼠的 Phenotypic 分析在产生猛烈老鼠表明了这条途径的坚韧性。重要地,这条途径在高效率交付完全的基因大美人(Arntl 上的 100% 并且 91% 在 Prrt2 上) 在猴子胚胎。最后,我们能在一个单个步骤产生一只完全的 Prrt2 猛烈猴子,表明在很快建立编辑基因的猴子模型的这条途径的实用性。 | Erwei Zuo Yi-Jun Cai Kui Li Yu Wei Bang-An Wang Yidi Sun Zhen Liu Jiwei Liu Xinde Hu Wei Wei Xiaona Huo Linyu Shi Cheng Tang Dan Liang Yan Wang Yan-Hong Nie Chen-Chen Zhang Xuan Yao Xing Wang Changyang Zhou Wenqin Ying Qifang Wang Ren-Chao Chen Qi Shen Guo-Liang Xu Jinsong Li Qiang Sun Zhi-Qi Xiong Hui Yang | 2017 | Cell Research2017，27，7： | 21 |
| 3 | China's Opening up after 40 Years: Standing at a Historic Turning Point显示文摘 | Jiandong Ju Xinding Yu | 2018 | China & World Economy2018，26，2： | 9 |
| 4 | Facile synthesis of PDMAEMA-coated hollow mesoporous silica nanoparticles and their pH-responsive controlled release显示文摘 | Faqi Yu Xinde Tang Meishan Pei | 2013 | Microporous and Mesoporous Materials2013，，： | 1 |
| 5 | Pilot Test of Weak Alkaline System ASP Flooding in Secondary Layer With Small Well Spacing显示文摘 | Wan Xinde Huang Mei Yu Huiyu | 2006 | SPEI044162006，，： | 1 |
| 6 | Triple stimuli‐responsive amphiphilic glycopolymer显示文摘 | Wenjuan Guo Tieshi Wang Xinde Tang Qun Zhang Faqi Yu Meishan Pei | 2014 | J Polym Sci Part A: Polym Chem2014，，15： | 1 |
| 7 | Pilot test of weakalkaline system ASP flooding in secondary layer with s-mall well spacing显示文摘 | Wan Xinde Huang Mei Yu Huiyu | 2006 | SPE 1044162006，，： | 1 |
| 8 | Removal of Cu, Zn, and Cd from aqueous solutions by the dairy manure-derived biochar显示文摘 | Xiaoyun Xu Xinde Cao Ling Zhao Hailong Wang Hongran Yu Bin Gao | 2013 | Environmental Science and Pollution Research2013，，1： | 1 |
| 9 | Removal of Cu, Zn, and Cd from aqueous solutions by the dairy manure-derived biochar显示文摘 | Xiaoyun Xu Xinde Cao Ling Zhao Hailong Wang Hongran Yu Bin Gao | 2013 | Environmental Science and Pollution Research2013，，1： | 1 |
| 10 | A quantitative study on planar mechanical anisotropy of a Mg-2Zn-1Ca alloy显示文摘A TD-tilted basal texture in Mg alloys often generates a strong planar mechanical anisotropy.Unfortunately,there has been not a quantitative study on this issue.In the present study,the mechanisms for the anisotropy of tensile yield strength in RD-TD plane were quantitatively studied for a Mg-2Zn-1Ca alloy with different grain sizes and textures.Here,RD and TD refer to the rolling direction and transverse direction of the plate.The results show that there is a strong planar yield anisotropy(~24±5 MPa),regardless of grain size,while this yield anisotropy is absent in texture with a circular distribution of basal poles.The examination of microstructure and X-ray diffraction analysis reveals that,beside basal slip as the predominant mode under both RD-tension and TD-tension,prismatic slip in RD-tension and both prismatic slip and extension twinning in TD-tension are also important.The parameters of Hall-Petch relation are also used to further analyze the mechanism for yield anisotropy.The changeable intercept,σ_(0),and invariant Hall-Petch slope,k,between RD-tension and TD-tension are rationalized accounting for this anisotropy.The reasons why there are differentσ0and similar k between TD-tension and RD-tension are quantitively discussed.At last,a texture design for decreasing the planar yield anisotropy is given. | Xinde Huang Yunchang Xin Yu Cao Guangjie Huang Wei Li | 2022 | Journal of Materials Science & Technology2022，，14： | 0 |
| 11 | National Concentration of High-tech Products:The Second Great Diverqence?显示文摘Based on the product-country level trade data from 2004 to 2017,as well as the High-Tech Products Catalog from the US Census Bureau,this paper examines empirically the current phenomenon of'national concentration'in high-tech exports.The results show that the phenomenon of'national concentration'not only exists but also tends to be self-reinforcing.Compared with other products,the exports of high-tech products tend to be concentrated in certain countries,and this concentration trends were further strengthened after the global financial crisis of2008-2009.The national concentration of R&D activities may be one of the important causes of the national concentration of high-tech products.This pattern remains robust when we further use the value-added export data and different definitions of high-tech products.We argue that the phenomenon of'national concentration'of high-tech exports may herald the arrival of the'Second Great Divergence'-the divergence between innovative and manufacturing activities-in the global economy. | Bing Lu Jiandong Ju Xinding Yu | 2023 | China & World Economy2023，31，1： | 0 |
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