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| 1 | Effect of burden and origin sites of premature ventricular contractions on left ventricular function by 7-day Holter monitor显示文摘Recent studies have shown that premature ventricular contractions(PVCs) could enlarge the heart,but its risk factors are incompletely understood as a single 24-hour recording cannot reflect the true PVC burden due to day-to-day variability.Our purpose was to investigate the effect of burden and origin sites on left ventricular(LV) function in patients with PVCs by 7-day Holter electrocardiography(ECG).From May 2012 to August2013,112 consecutive patients with PVCs were recruited from the authors' affiliated hospital.All patients received2-dimensional transthoracic echocardiography,12-lead routing ECG and 7-days Holter ECG.Serum N-terminal probrain natriuretic peptide(NT-proBNP) levels were measured.A total of 102 participants with PVCs were included in the final analysis.Origin of PVCs from the tricuspid annulus had the highest burden and NT-proBNP level.LV papillary muscle had a higher LV ejection fraction(EF) level and a lower LV end-systolic dimension(ESD) than other PVC foci(P<0.05).The high burden group had a higher LV end-diastolic dimension(EDD) and LVESD but lower LVEF than the other two groups(P<0.05).Female,older age,physical work,and history of PVCs had a significantly positive correlation with symptoms.Male,older age,physical work,and high burden were positive predictors of enlarged LVEDD,LVESD and higher serum NT-proBNP level,but lower LVEF.Seven-day dynamic ECG Holter monitor showed the true PVC burden on patients with PVCs.PVCs with a lower burden or origin from the LV papillary muscle and the fascicle were relatively benign,while PVCs with a higher burden or origin from the tricuspid annulus may lead to cardiac dysfunction. | Wenhua Xu Mingfang Li Minglong Chen Bing Yang Daowu Wang Xiangqing Kong Hongwu Chen Weizhu Ju Kai Gu Kejiang Cao Hailei Liu Qi Jiang Jiaojiao Shi Yan Cui Hong Wang | 2015 | The Journal of Biomedical Research2015，29，6： | 4 |
| 2 | Progress of Jinping Underground laboratory for Nuclear Astrophysics(JUNA)显示文摘Jinping Underground laboratory for Nuclear Astrophysics(JUNA) will take the advantage of the ultra-low background of CJPL lab and high current accelerator based on an ECR source and a highly sensitive detector to directly study for the first time a number of crucial reactions occurring at their relevant stellar energies during the evolution of hydrostatic stars. In its first phase, JUNA aims at the direct measurements of^(25)Mg(p,γ)^(26)Al,^(19)F(p,α)^(16)O,^(13)C(α,n)^(16)O and ^(12)C(α,γ)^(16)O reactions. The experimental setup,which includes an accelerator system with high stability and high intensity, a detector system, and a shielding material with low background, will be established during the above research. The current progress of JUNA will be given. | WeiPing Liu ZhiHong Li JiangJun He XiaoDong Tang Gang Lian Zhu An JianJun Chang Han Chen QingHao Chen XiongJun Chen ZhiJun Chen BaoQun Cui XianChao Du ChangBo Fu Lin Gan Bing Guo GuoZhu He Alexander Heger SuQing Hou HanXiong Huang Ning Huang BaoLu Jia LiYang Jiang Shigeru Kubono JianMin Li KuoAng Li Tao Li YunJu Li Maria Lugaro XiaoBing Luo HongYi Ma ShaoBo Ma DongMing Mei YongZhong Qian JiuChang Qin Jie Ren YangPing Shen Jun Su LiangTing Sun WanPeng Tan Isao Tanihata Shuo Wang Peng Wang YouBao Wang Qi Wu ShiWei Xu ShengQuan Yan LiTao Yang Yao Yang XiangQing Yu Qian Yue Sheng Zeng HuanYu Zhang Hui Zhang LiYong Zhang NingTao Zhang QiWei Zhang Tao Zhang XiaoPeng Zhang XueZhen Zhang ZiMing Zhang Wei Zhao Zuo Zhao Chao Zhou | 2016 | Science China(Physics,Mechanics & Astronomy)2016，59，4： | 3 |
| 3 | The dependence of cumulative ^(238)U(n,f) fission yield on incident-neutron energy显示文摘This work is aim at studying the dependence of fission yields on incident neutron energy, so as to produce evaluated yield sets of the energy dependence. Experimental data at different neutron energies for gas fission products 85m,87,88Kr and 138Xe resulting from the 238U(n, f) reaction are processed using codes AVERAGE for weighed average and ZOTT for simultaneous evaluation. Energy dependence of the cumulative fission product yields on the incident neutron is presented. The evaluated curve of product yield is compared with the results calculated by the TALYS-0.64 code. The present evaluation is consistent with other main libraries in error permission. The fit curve of 87,88Kr can be recommended to predict the unmeasured fission yields. Comparisons of the evaluated energy dependence curves with theoretical calculated results show that the predictions using purely theoretical model for the fission process are not sufficiently accurate and reliable for the calculations of the cumulative fission yields for the 238U(n,f). | ZHENG Na ZHONG Chunlai MA Liyong CHEN Zhongjing LI Xiangqing LIU Tingjin CHEN Jinxiang FAN Tleshuan | 2009 | Nuclear Science and Techniques2009，20，5： | 1 |
| 4 | Environmental assessment, management and utilization of red mud in China显示文摘 | Wanchao Liu Xiangqing Chen | 2014 | Journal of Cleaner Production2014，84，： | 1 |
| 5 | Laser induced thermal effect on upconversion luminescence and temperature-dependent upconversion mechanism in Ho 3+ /Yb 3+ -codoped Gd 2 (WO 4 ) 3 phosphor显示文摘 | Wei Liu Jiashi Sun Xiangping Li Jinsu Zhang Yue Tian Shaobo Fu Hua Zhong Tianhong Liu Lihong Cheng Haiyang Zhong Haiping Xia Bin Dong Ruinian Hua Xiangqing Zhang Baojiu Chen | 2013 | Optical Materials2013，，7： | 1 |
| 6 | TRAF5 and TRAF31P2gene polymorphisms are associated with Behcet’s dis-ease and Vogt- Koyanagi- Harada syndrome : a case- con-trol study显示文摘 | XiangQ Chen L Hou S | 2014 | PLoS One2014，，84： | 1 |
| 7 | Mechanisms of flotation separation of diaspore and kaolinite by quaternary ammonium salt DTAL 显示文摘 | Chen Xiangqing Hu Yuehua Wang Yuhua | 2004 | Trans Nonferrous Met Soc China2004，14，3： | 1 |
| 8 | Experimental and Theoretical Study on the Flexural Behavior of Recycled Concrete Beams Reinforced with GFRP Bars显示文摘This paper experimentally investigated the flexural behavior of reinforced recycled aggregate concrete(RAC)beams reinforced with glass fiber-reinforced polymer(GFRP)bars.A total of twelve beams were built and tested up to failure under four-point bending.The main parameters were reinforcement ratio(0.38%,0.60%,and 1.17%),recycled aggregate replacement ratio(R=0,50%,and 100%)and longitudinal reinforcement types(GFRP and steel).The flexural capacity,failure modes,flexibility deformation,reinforcement strains and crack distribution of the tested beams were investigated and compared with the calculation models of American code ACI 440.1-R-15,Canadian code CSA S806-12 and ISIS-M03-07.The tested results indicated that the reinforcement ratio has great influence on the ultimate load,crack width and deflection of GFRP-RAC beams,the recycled aggregate replacement ratio has little influence on it.However,it was found that the reinforcement ratio has no obvious influence on the cracking load which was only related to the recycled aggregate replacement ratio.The average cracking load decreased by 5%and 15%as the recycled aggregate replacement ratio increased from 0 to 50%and 100%.For the steel-RAC beams,the ultimate load was found to be about 1/2 of the ultimate load of GFRP-RAC beam under the same condition and the trend of strain,deflection and crack width were different from GFRP-RAC beams.This is due to the different material properties of GFRP bars and steel rebar.On the other hand,the calculation results showed that ACI 440.1-R-15 and CSA S806-12 underestimated the ultimate load of GFRP-RAC beams.Moreover,the deflection prediction of GFRP-RAC beams by CSA S806-12 is relatively accurate compared with ACI 440.1-R-15 and ISIS-M03-07.As for the prediction of crack width,the results of ACI 440.1-R-15 prediction were in good agreement with the experimental results at the ultimate load,with the average value of 1.09±0.28. | Xinzhan Chen Xiangqing Kong Ying Fu Wanting Sun Renguo Guan | 2021 | Journal of Renewable Materials2021，9，6： | 0 |
| 9 | 2 - 30 Progress in Analyzing RIBLL1 17F+p Experimental Data显示文摘 | He Jianjun Hu Jun Xu Shiwei Chen Zhiqiang Zhang Xueying Wang Jiansong Yu Xiangqing Li Long Zhang Liyong Yang Yanyun Ma Peng Wang Hongwei Tian Wendong Zhang Xueheng Su Jun Li Ertao Hu Zhengguo Guo Zhongyan Xu Xing Yuan Xiaohua Lu Wan Lei Xiangguo Yu Yuhong Tang Shuwen Ye Ruiping Chen Jinda Jin Shilun Du Chengming Wang Shitao Ma Junbing Liu Longxiang Bai Zhen Sun Zhiyu Li Xiangqing Zhang Yuhu Zhou Xiaohong Xu Hushan | 2010 | IMP & HIRFL Annual Report2010，，1： | 0 |
| 10 | 2 - 9 S-factor in 6Li(p,Y) 7Be Reaction at Low Energy显示文摘 | Chen Size He Jianjun Xu Shiwei Zhang Liyong Hu Jun Hou Suqing Yu Xiangqing Ma Shaobo Claus Rolls | 2013 | IMP & HIRFL Annual Report2013，，1： | 0 |
| 11 | Micro Hierarchical Structure and Mechanical Property of Sparrow Hawk (Accipiter nisus) Feather Shaf显示文摘In this study,the real 3D model of the feather shaft that is composed of medulla and cortex is characterized by X-ray computer tomography,and the structural features are quantitatively analyzed.Compression and tensile tests are conducted to evaluate the mechanical performance of the feather shaft and cortex at different regions.The analysis of the 3D model shows that the medulla accounts for∼70%of the shaft volume and exhibits a closed-cell foam-like structure,with a porosity of 59%.The cells in the medulla show dodecahedron and decahedron morphology and have an equivalent diameter of∼30μm.In axial compression,the presence of medulla enhances the shaft stability.Especially,the combined effect of the medulla and cortex increases the buckling strength of the middle and distal shaft by 77%and 141%,respectively,compared to the calculated value of the shaft using linear mixed rule.The tensile properties of the cortex along the shaft axis are anisotropic because of the different fiber structures.As the fiber orientation gradually becomes uniform in the axial direction,the Young’s modulus and tensile strength of the cortex on the dorsal gradually increase from calamus to the distal shaft,and the fracture mode changes from tortuous fracture to V-shaped fracture.The cortex on the lateral shows the opposite trend,that is the distal shaft becomes weaker due to fiber tangles. | Yichen Lu Zongning Chen Enyu Guo Xiangqing Kong Huijun Kang Yanjin Xu Rengeng Li Guohua Fan Tongmin Wang | 2021 | Computer Modeling in Engineering & Sciences2021，，5： | 0 |
| 12 | β-decay study of neutron-rich nucleus ^(34)Al显示文摘The'island of inversion'has been known for over a quarter century,since Warburton et al.[1]proposed that nuclei with intruder ground states would constitute a 3×3 square with Z=10-12,N=20-22 in 1990.Uncovering the underlying inversion mechanism and exploring the scope of the island have attracted significant theoretical and experimental efforts in the following years.Now it is well known that the reduction of N=20 shell gap,which is likely caused by the | Rui Han XiangQing Li WeiGuang Jiang ZhiHuan Li Hui Hua ShuangQuan Zhang CenXi Yuan DongXing Jiang YanLin Ye Jing Li ZongHao Li FuRong Xu QiBo Chen Jie Meng JianSong Wang Chuan Xu YeLei Sun ChunGuang Wang HongYi Wu ChenYang Niu ChenGuang Li Chao He Wei Jiang PengJie Li HongLiang Zang Jun Feng SiDong Chen Qiang Liu XiaoChi Chen HuShan Xu ZhengGuo Hu YanYun Yang Peng Ma JunBing Ma ShiLun Jin Zhen Bai MeiRong Huang Yuan Jie Zhou WeiHu Ma Yong Li XiaoHong Zhou YuHu Zhang GuoQing Xiao WenLong Zhan | 2017 | Science China(Physics,Mechanics & Astronomy)2017，60，4： | 0 |
| 13 | Synergy of mesoporous SnO_(2)and RbF modification for high-efficiency and stable perovskite solar cells显示文摘Electron transport layer(ETL)is very critical to the performance of perovskite solar cells(PSCs),and optimization work on ETL has received extensive attentions especially on tin oxide(SnO_(2))since it is an excellent ETL material widely applied in high-efficiency PSCs.Thereinto,introducing mesoporous structure and surface modification are two important approaches which are commonly applied.Herein,based on the previous work in low-temperature fabrication process of mesoporous SnO_(2)(mSnO_(2)),we introduced a modification process with rubidium fuoride(Rb F)to the m-SnO_(2)ETL,and successfully achieved a synergy of the m-SnO_(2)and Rb F modification:not only the shortcoming of the m-SnO_(2)in interfacial traps was overcome,but also the carrier collection efficiency was further improved.The PSCs based on the m-SnO_(2)ETL with Rb F modification demonstrated outstanding performances:a champion power conversion efficiency(PCE)of 22.72%and a stability performance of maintaining 90%of the initial PCE after 300 h of MPP tracking were obtained without surface passivation of perovskite film.Hence,utilizing the abovementioned synergy is a cost-effective and feasible strategy for fabricating high-efficiency and stable PSCs since the fabrication process of the m-SnO_(2)ETL is a kind of low temperature process and RbF is cheap. | Qian Chen Changtao Peng Lin Du Tian Hou Wenjing Yu Dong Chen Hui Shu Dejun Huang Xiangqing Zhou Jinyang Zhang Wenfeng Zhang Haijin Li Jiale Xie Yuelong Huang | 2022 | Journal of Energy Chemistry2022，31，3： | 0 |
| 14 | PBS:a prospective longitudinal multi-omics bariatric surgery cohort显示文摘Dear Editor,Obesity is an increasingly prevalent global health concern affecting∼13%of the worldwide population and is associated with the development of conditions such as insulin resistance,hypertenion,hyperlipidemia,and non-alcoholic fatty liver disease^([1]). | Yuwen Jiao Jiaming Xue Shuai Chen Wei Sun PBS Cohort Study Xiangqing Kong Lianmin Chen Liming Tang | 2023 | Precision Clinical Medicine2023，6，4： | 0 |
| 15 | 2 - 18 A Low-energy Platform for Nuclear Astrophysics显示文摘 | Chen Size He Jianjun Xu Shiwei Zhang Liyong Hu Jun Hou Suqing Yu Xiangqing Ma Shaobo Claus Rolls | 2012 | IMP & HIRFL Annual Report2012，，1： | 0 |
| 16 | 2-16 Experimental Study of 13N(α,p)16O at the Stellar Energies显示文摘The presolar SiC grains[1]carry the original stellar nucleosynthesis signature.Their isotopic anomalies compared to the sun are the strong constrains in the supernovae(SN)model calculations.The 15N-excess in some SiC-AB grains(12C/13C<10 and 14N/15N<272)is one of the challenges of core-collapse supernovae(CCSNe)models[2].Recently,Pignatari pointed out that the entrainment of H-rich material into the He shell before the SN explosion allows the coproduction of 13C,15N and 26Al,which provides a new production scenario for SiC-AB grains[2].In the He shell nucleosynthesis,the 13C is produced through 12C(p,γ)13N(β+γ)13C reaction.The 14N is synthesized through 13N(n,γ)and 13C(p,γ)reactions. | Lin Weiping Ma Shaobo Hu Jun Bai Zhen Chen Han Chen Zhijun Duan Fangfang Gao Bingshui Gao Zhihao Hou Suqing Ji Liancheng Jia Baolu Jiao Lei Jin ShuYa Liu Xingquan Li Kuoang Lu Tan Ma Junbing Ma Peng Tang Xiaodong Wang Xinyu Xu Shiwei Yang Yanyun Yu Gongming Yu Xiangqing Zhai Yaojie Zhang Ningtao Zhang Xing | 2016 | IMP & HIRFL Annual Report2016，，1： | 0 |
| 17 | Exploration of a Sequential Gp140-Gp145 Immunization Regimen with Heterologous Envs to Induce a Protective Cross-Reactive HIV Neutralizing Antibody Response In Non-human Primates显示文摘Raising a heterologous tier 2 neutralizing antibody(nAb)response remains a daunting task for HIV vaccine development.In this study,we explored the utility of diverse HIV-1 envelope(Env)immunogens in a sequential immunization scheme as a solution to this task.This exploration stemmed from the rationale that gp145,a membrane-bound truncation form of HIV Env,may facilitate the focusing of induced antibody response on neutralizing epitopes when sequentially combined with the soluble gp140 form as immunogens in a prime-boost mode.We first showed that gp140 DNA prime-gp145 Tiantan vaccinia(TV)boost likely represents a general format for inducing potent nAb response in mice.However,when examined in rhesus macaque,this modality showed little effectiveness.To improve the efficacy,we extended the original modality by adding a strong protein boost,namely native-like SOSIP.664 trimer displayed on ferritin-based nanoparticle(NP),which was generated by a newly developed click approach.The resulting three-immunization regimen succeeded in eliciting tier-2 nAb response with substantial breadth when implemented in rhesus macaque over a short 8-week schedule.Importantly,the elicited nAb response was able to effectively contain viremia upon a heterologous SHIV challenge.Collectively,our studies highlighted that diversification of Env immunogens,in both types and formulations,under the framework of a sequential immunization scheme might open new opportunity toward HIV vaccine development. | Xiangqing Ding Kangli Cao Jing Wang Yanmin Wan Qinyun Chen Yanqin Ren Yongtang Zheng Mingzhao Zhu Renrong Tian Wenjun Wang Chen Zhao Xiaoyan Zhang Jianqing Xu | 2021 | Virologica Sinica2021，36，4： | 0 |
| 18 | 2-8 Measurement of 11B(p,r)12 C Astrophysical S Factors at Low Energies显示文摘Theoretical models of stellar evolution predict negligible quantities of 6Li, 9Be, and 11B in the hydrogen burning phases of a star’s evolution[1]. The primordial Big-Bang nucleosynthesis (BBN) model might be more generous in its production of these elements[2]. The radiative-capture cross section for proton capture on 11B leading to 12C is small at astrophysically interesting energies because of the large Coulomb barrier. | He Jianjun Xu Shiwei Jia Baolu Chen Size Ma Shaobo Hou Suqing Hu Jun Zhang Liyong Yu Xiangqing | 2015 | IMP & HIRFL Annual Report2015，，1： | 0 |
| 19 | Risk of interstitial lung disease with the use of programmed cell death 1 (PD-1) inhibitor compared with programmed cell death ligand 1 (PD-L1) inhibitor in patients with breast cancer: A systematic review and meta-analysis显示文摘Background:Programmed cell death 1(PD-1)and programmed cell death ligand 1(PD-L1)inhibitors have become integral elements within the current landscape of breast cancer treatment modalities;however,they are associ-ated with interstitial lung disease(ILD),which is rare but potentially fatal.Notably,only a few studies have compared the difference in ILD incidence between PD-1 and PD-L1 inhibitors.Therefore,this study aimed to assess the discrepancies regarding ILD risk between the two immune checkpoint inhibitors.We also reported three cases of ILD after PD-1 inhibitor treatment.Methods:We comprehensively searched PubMed,EMBASE,and the Cochrane Library to identify clinical trials that investigated PD-1/PD-L1 inhibitor treatment for patients with breast cancer.Pooled overall estimates of incidence and risk ratio(RR)were calculated with a 95%confidence interval(CI),and a mirror group analysis was per-formed using eligible studies.Results:This meta-analysis included 29 studies with 4639 patients who received PD-1/PD-L1 inhibitor treatment.A higher ILD incidence was observed among 2508 patients treated with PD-1 inhibitors than among 2131 patients treated with PD-L1 inhibitors(0.05 vs.0.02).The mirror group analysis further revealed a higher ILD event risk in patients treated with PD-1 inhibitors than in those treated with PD-L1 inhibitors(RR=2.34,95%CI,1.13-4.82,P=0.02).Conclusion:Our findings suggest a greater risk of ILD with PD-1 inhibitors than with PD-L1 inhibitors.These findings are instrumental for clinicians in treatment deliberations,and the adoption of more structured diagnostic approaches and management protocols is necessary to mitigate the risk of ILD. | Lijuan Guo Xiaoyi Lin Xin Lin Yulei Wang Jiali Lin Yi Zhang Xiangqing Chen Miao Chen Guochun Zhang Yifang Zhang | 2024 | Cancer Pathogenesis and Therapy2024，2，2： | 0 |
| 20 | Investigation of Proton Resonant Properties in laNe via 17F+p and Its Astrophysical Implications for 14O(α,p)17F Stellar Reaction显示文摘 | Hu Jun He Jianjun Xu Shiwei Chen Zhiqiang Zhang Xueying Wang Jiansong Yu Xiangqing Li Long Zhang Liyong Yang Yanyun Ma Peng Wang Hongwei Tian Wendong Yuan Xiaohua Lu Wan Zhang Xueheng SuJun Li Ertao Hu Zhengguo Guo Zhongya n Xu Xing Lei Xiangguo Yu Yuhong Tang Shuwen Ye Ruiping Chen Jinda Jin Shilun Du Chengming Wang Shitao Ma Junbing Liu Longxiang Bai Zhen Sun Zhiyu Li Xiangqing Zhang Yuhu Zhou Xiaohong Xu Hushan | 2009 | 近代物理研究所和兰州重离子加速器实验室年报:英文版2009，，1： | 0 |
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