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4篇 您的检索式:作者名="Xavier Torras"
    题名 作者 年代 出处 被引量
1Cytokine production in patients with cirrhosis and TLR4 polymorphisms显示文摘AIM:To analyze the cytokine production by peripheral blood cells from cirrhotic patients with and without TLR4 D299G and/or T399I polymorphisms.METHODS:The study included nine patients with cirrhosis and TLR4 D299G and/or T399I polymorphisms,and 10 wild-type patients matched for age,sex and degree of liver failure.TLR4 polymorphisms were determined by sequence-based genotyping.Cytokine production by peripheral blood cells was assessed spontaneously and also after lipopolysaccharide(LPS)and lipoteichoic acid(LTA)stimulation.RESULTS:Patients with TLR4 polymorphisms had a higher incidence of previous hepatic encephalopathy than wild-type patients(78%vs 20%,P=0.02).Spontaneous production of interleukin(IL)-6 and IL-10 was lower in patients with TLR4 polymorphisms than in wild-type patients[IL-6:888.7(172.0-2119.3)pg/m L vs 5540.4(1159.2-26053.9)pg/m L,P<0.001;IL-10:28.7(6.5-177.1)pg/m L vs 117.8(6.5-318.1)pg/m L,P=0.02].However,the production of tumor necrosis factor-α,IL-6 and IL-10 after LPS and LTA stimulation was similar in the two groups.CONCLUSION:TLR4 polymorphisms were associated with a distinctive pattern of cytokine production in cirrhotic patients,suggesting that they play a role in the development of cirrhosis complications.Juan Camilo Nieto Elisabet Sánchez Eva Román Silvia Vidal Laia Oliva Carlos Guarner-Argente Maria Poca Xavier Torras Cándido Juárez Carlos Guarner German Soriano 2014World Journal of Gastroenterology2014,20,46:5
2Acute Hemodynamic Response to β-Blockers and Prediction of Long-term Outcome in Primary Prophylaxis of Variceal Bleeding显示文摘Càndid Villanueva Carles Aracil Alan Colomo Virginia Hernández–Gea Josep M. López–Balaguer Cristina Alvarez–Urturi Xavier Torras Joaquim Balanzó Carlos Guarner 2009Gastroenterology2009,,1:1
3Acute Hemodynamic Response to β-Blockers and Prediction of Long-term Outcome in Primary Prophylaxis of Variceal Bleeding显示文摘Càndid Villanueva Carles Aracil Alan Colomo Virginia Hernández–Gea Josep M. López–Balaguer Cristina Alvarez–Urturi Xavier Torras Joaquim Balanzó Carlos Guarner 2009Gastroenterology2009,,1:1
4Immunosuppression without steroids in liver transplantation is safe and reduces infection and metabolic complications: Results from a prospective multicenter randomized study显示文摘Laura Lladó Xavier Xiol Joan Figueras Emilio Ramos Roberto Memba Teresa Serrano Jaume Torras Agustin Garcia-Gil Ignacio Gonzalez-Pinto Jose Castellote Carme Baliellas Joan Fabregat Antoni Rafecas the THOSIN Study Group 2006Journal of Hepatology2006,,4:1
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