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| 1 | Estimation of visceral fat is useful for the diagnosis of significant fibrosis in patients with non-alcoholic fatty liver disease显示文摘BACKGROUND Obesity is a risk factor for non-alcoholic fatty liver disease(NAFLD),although obese patients with NAFLD do not always develop significant fibrosis.The distribution of body fat could predict the risk of NAFLD progression.AIM To investigate the role of bioelectrical impedance-estimated visceral fat(VF)in assessing NAFLD severity.METHODS In this cross-sectional study,patients with biopsy-proven NAFLD were prospectively included.All patients underwent anthropometric evaluation,blood tests and bioelectrical impedance analysis.RESULTS Between 2017 and 2020,119 patients were included[66.4%male,56 years(SD 10.7),62.2%obese,61.3%with metabolic syndrome].Sixty of them(50.4%)showed significant fibrosis(≥F2)in liver biopsy.Age,VF and metabolic syndrome were associated with significant fibrosis(61 years vs 52 years,16.4 vs 13.1,73.3%vs 49.2%,respectively;P<0.001 for all).In the multivariate analysis,VF and age were independently associated with significant fibrosis(VF,OR:1.11,95%CI:1.02-1.22,P=0.02;age,OR:1.08,95%CI:1.03-1.12,P<0.01).A model including these variables showed and area under the receiver operating characteristic curve(AUROC)of 0.75,which was not inferior to transient elastography or NAFLD fibrosis score AUROCs.We developed a nomogram including age and VF for assessing significant fibrosis in routine practice.CONCLUSION VF is a surrogate marker of liver fibrosis in patients with NAFLD.Bioelectrical impedance analysis is an inexpensive and simple method that can be combined with age to guide patient referral when other resources may be unavailable. | Marta Hernández-Conde Elba Llop Carlos Fernández Carrillo Beatriz Tormo Javier Abad Luis Rodriguez Christie Perelló Marta López Gomez JoséLuis Martínez-Porras Natalia Fernández Puga Maria Trapero-Marugan Enrique Fraga Carlos Ferre Aracil JoséLuis Calleja Panero | 2020 | World Journal of Gastroenterology2020，26，42： | 2 |
| 2 | Integrated Biodiesel Production:A Comparison of Different Homogeneous Catalysts Systems显示文摘 | GEMMA VICENTE MERCEDES MARTINEZ JOSE ARACIL | 2004 | Bioresource Technology2004，92，： | 1 |
| 3 | A new swing-up law for the Furuta pendulum显示文摘 | GORDILLO F ACOSTA J A ARACIL J | 2003 | International Journal of Control2003，76，8： | 1 |
| 4 | A heterogeneous modular robotic design for fast response to a diversity of tasks显示文摘 | Baca J Ferre M Aracil R | 2012 | Robotics andAutonomous Systems2012，60，4： | 1 |
| 5 | Generalized control method by state convergence for teleoperation systems with time delay 显示文摘 | AZORIN J M REINOSO O ARACIL R | 2004 | Automatica2004，40，9： | 1 |
| 6 | A randomized controlled trial comparing ligation and sclerotherapy as emergency endoscopic treatment added to somatostatin in acute variceal bleeding 显示文摘 | Villanueva C Piqueras M Aracil C | 2006 | Hepatol2006，45，4： | 1 |
| 7 | Vision System for On-line Surface Inspection in Aluminum Casting Process显示文摘 | Fernandez C Platero C Campoy P Aracil R | 1993 | Industrial Electronics Control and Instrumentation1993，，3： | 1 |
| 8 | Acute hemodynamicresponse to beta-blockers and prediction of long-term outcomein primary prophylaxis of variceal bleeding显示文摘 | Villanueva C Aracil C Colomo A | 2009 | Gastroenterology2009，137，1： | 1 |
| 9 | Influence of spontaneous hemodynamic response on the efficacy of endoscopic therapy to prevent variceal rebleeding 显示文摘 | Aracil C Monfort D Piqueras M | 2005 | J Hepatol2005，42，2： | 1 |
| 10 | Higher education and graduate employment in Spain显示文摘 | Jose Gines Mora Jose Garcia Montalvo Adela Garcia Aracil | 2000 | European Journal of Education2000，，2： | 1 |
| 11 | Trocar site hernia after lapamscopic ventral hernia repair显示文摘 | Boldo' E Perez de Lucia G Aracil JP | 2007 | Sung Endosc2007，21，5： | 1 |
| 12 | Acute hemodynamic re-sponse to b-blockers and prediction of long-term outcome in primary prophylaxis of variceal bleeding显示文摘 | Vil anueva C Aracil C Colomo A | | 0，，： | 1 |
| 13 | Interleukin-6 deficiencyaffects bone marrow stromal precursors,resulting in defective hematopoietic support显示文摘 | Rodriguez Mdel C Bernad A Aracil M | 2004 | Blood2004，103，9： | 1 |
| 14 | Trocar site hernia after laparoscopic ventral hernia repair显示文摘 | Boldo'E Perez de Lucia G Aracil JP | 2007 | Surg Endosc2007，21，5： | 1 |
| 15 | Development of ascites in compensated cirrhosis with severe portal hypertension treated with β-blockers显示文摘 | Hernandez-Gea V Aracil C Colomo A | | 0，，03： | 1 |
| 16 | Kinetics of sunflower oil methanolysis显示文摘 | VICENTE G MARTINEZ M ARACIL J | 2005 | had Eng Chem Res2005，44，15： | 1 |
| 17 | Current endoscopic therapy of variceal bleeding 显示文摘 | Candid Villanueva Allan Colomo Carlos Aracil | 2008 | Best Practice&Research2008，22，4： | 1 |
| 18 | Global stability analysis of fuzzy path tracking using frequency Response显示文摘 | ARACIL J HEREDIA G OLLERO A | 2000 | Engineering Applications of Artificial Intelligence2000，13，2： | 1 |
| 19 | A randomizedcontrolled trial comparing ligation and sclerotherapy as emergervcy endoscopic treatment added to somatostatin in acute varicealbleeding显示文摘 | VILLANUEVA C PIQUERAS M ARACIL C | 2006 | J Hepatol2006，45，4： | 1 |
| 20 | Adsorption equilibrium of α-amylase in aqueous solutions显示文摘 | Bautista L F Martinez M Aracil J | 1999 | AIChE Journal1999，45，： | 1 |
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