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| 1 | Robotic-assisted versus open total pancreatectomy: a propensity score-matched study显示文摘Background:Total pancreatectomy(TP)is a complex surgical procedure with significant postoperative morbidity.Despite the narrowed range of indications for TP,the introduction of neoadjuvant chemotherapy and the increasing complexity of surgical resections performed in high-volume centers has increased the number of annually performed TPs,especially regarding malignant disease.The introduction of robotic-assisted pancreatic surgery has provided a novel and minimally invasive approach for TP,yet the feasibility of this technique is still unknown.This study assessed the safety and efficacy of robotic-assisted total pancreatectomy(RTP)compared to conventional open total pancreatectomy(OTP).Methods:All patients who underwent TP between March 2015 and July 2019 in a high-volume institution for pancreatic surgery were included in this retrospective study.Clinical data and perioperative outcomes were derived from the prospectively maintained institutional database.A 1:1 propensity score matching(PSM)method was utilized to compare the RTP and OTP cohorts to minimize bias.Results:A standardized surgical protocol was utilized for RTP following a learning curve of RPD and RDP.The median operative time for patients who underwent RTP was significantly decreased compared to those who underwent OTP[300(IQR,250-360)vs.360 min(IQR,300-525),P=0.031].Additionally,en bloc resection and spleen-preserving rates were also higher in the RTP cohort.Major 30-day morbidity(Clavien-Dindo>IIIa)and 90-day mortality were similar between the two cohorts.After a median follow-up time of 15(IQR,8-24)months,both the RTP and OTP cohorts had a comparable quality of life regarding exocrine and endocrine insufficiency.Conclusions:RTP appears to be safe and feasible when utilized in high-volume centers for the indicated management of benign and highly selected malignant pancreatic disease.However,further prospective randomized studies are needed to assess the feasibility of this approach. | Yuanchi Weng Mengmin Chen Georgios Gemenetzis Yusheng Shi Xiayang Ying Xiaxing Deng Chenghong Peng Jiabin Jin Baiyong Shen | 2020 | Hepatobiliary Surgery and Nutrition2020，9，6： | 3 |
| 2 | Outcomes of robotic surgery for pancreatic ductal adenocarcinoma显示文摘Background:To explore the effectiveness,safety,and efficacy of the robot-assisted surgery in the radical resection of pancreatic ductal adenocarcinoma(PDAC).Methods:The clinical data of 72 patients with PDAC who underwent radical resection using the da Vinci Surgical System from April 2010 to December 2014 were retrospectively analyzed.Results:Among these 72 patients,three were converted to conventional laparotomy due to the vascular invasion or due to the difficulties in tissue isolation from the surrounding organs.Among 39 patients who underwent the pancreatoduodenectomy,the average operative time was 395.3±118.8 min,and the mean intra-operative blood loss was 447.3±269.9 m L.Among 31 patients who underwent the distal pancreatectomy(DP),the average operative time was 185.5±74.1 min,and the mean intra-operative blood loss was 267.1±305.3 m L.In two patients who received the middle pancreatectomy(MP),the average operative time was 225 min and mean intra-operative blood loss was 100 m L.Among all the 72 patients,an average of 4.2±2.6 lymph nodes were dissected,with an average hospital stay of 22.6±10.7 days.Complications were observed in 18 patients,which included pancreatic fistula(n=11),bile leak(n=5),anastomotic bleeding(n=2),pancreatic fistula complicated with portal vein thrombosis(n=1),and anastomotic bleeding complicated with acute renal failure(n=1).Except that one patient died due to post-operative bleeding and acute renal failure,all the other patients were cured after conservative treatment.These 72 patients were followed for 1-45(15.6±5.8) months,during which 10 patients died.Eleven patients suffered from recurrence or metastasis,among which 6 had local recurrence,4 had liver metastasis,and 1 had ascites accompnaied with incision site tumor metastasis.Conclusions:Radical resection of PDAC by robotic surgical system is safe and feasible.It has less surgical trauma and enables faster post-operative recovery,and therefore can achieve the lymph node dissection scope and tumor resection margin required by the standards of radical resection for pancreatic cancer.Nevertheless,its long-term efficacy requires further validation. | Qian Zhan Xiaxing Deng Yuanchi Weng Jiabin Jin Zhichong Wu Hongwei Li Baiyong Shen Chenghong Peng | 2015 | Chinese Journal of Cancer Research2015，27，6： | 3 |
| 3 | Downregulation of gas5 increases pancreatic cancer cell proliferation by regulating CDK6显示文摘 | Xiongxiong Lu Yuan Fang Zhengting Wang Junjie Xie Qian Zhan Xiaxing Deng Hao Chen Jiabin Jin Chenghong Peng Hongwei Li Baiyong Shen | 2013 | Cell and Tissue Research2013，，： | 2 |
| 4 | Preparation and Electrochemical Performance of Li[Ni1/3Co1/3Mn1/3]O2 Synthesized Using LizCO3 as Template显示文摘 | Jibin Zhang Yanjun Zhong Xiaxing Shi Zhuo Zheng Weibo Hua Yanxiao Chen Wenyuan Liu Benhe Zhong | 2015 | Chinese Journal of Chemistry2015，33，11： | 2 |
| 5 | Chronic Gastrointestinal Inflammation Induces Anxiety-Like Behavior and Alters Central Nervous System Biochemistry in Mice显示文摘 | Premysl Bercik Elena F. Verdu Jane A. Foster Joseph Macri Murray Potter Xiaxing Huang Paul Malinowski Wendy Jackson Patricia Blennerhassett Karen A. Neufeld Jun Lu Waliul I. Khan Irene Corthesy–Theulaz Christine Cherbut Gabriela E. Bergonzelli Stephen M. | 2010 | Gastroenterology2010，，6： | 1 |
| 6 | lntegrative analysis of HIF binding and transactivation reveals its role in maintaining histone methylation homeostasis显示文摘 | XiaX Lemieux ME Li W | | 0，，： | 1 |
| 7 | AnovelSTSmarkerforpoly- phenol oxidase activity in bread wheat显示文摘 | Sun D J HeZH XiaX C etal | 2005 | Molecular Breeding2005，16，： | 1 |
| 8 | Prostagtandinpromotionofosteocytegapjunctionfunctionthroughtranscriptionalregulationofconnexin43byglycogensynthasekinase3/betacateninsignaling显示文摘 | XiaX BatraN JiangJX etal | 2010 | MolCellBiol2010，30，1： | 1 |
| 9 | Effects of the chemical foaming agents on mechanical properties and rheological behavior of the bamboo powder/polypropylene foamed composite 显示文摘 | ZHOU Xiaxing LIN Qiaojia CHEN Lihui | 2012 | Bioresources2012，7，2： | 1 |
| 10 | Ananthocyanin-richextract from black rice enhances atherosclerotic plaque stabilization in apolipoprotein E-deficient mice显示文摘 | XiaX LingW MaJ | | 0，，： | 1 |
| 11 | Effects of chemical foaming agents on the physico-mechanical properties and rheological behavior of bamboo powder- polypropylene foaming composites显示文摘 | Zhou Xiaxing Chen Lihui Lin Qiaojia | 2012 | BioResources2012，7，2： | 1 |
| 12 | Rock damage control in bedrock blasting excavation for a nuclear power plant显示文摘 | LI H B XIAX LI J C | 2011 | International Journal of Rock Mechanics and Mining Sciences2011，48，2： | 1 |
| 13 | The mitochondrial 12SrRNA gene in two ramily Mongolia with matrilineal aminoglycoside ototoxicity 显示文摘 | XiaX Radnanbaxar J | 1997 | J Med Genet1997，34，2： | 1 |
| 14 | A new HCV genotype 6 subtype designated 6v was confirmed with three complete genome sequences 显示文摘 | XiaX S Wang Y Z Li C H | 2009 | Journal of Clinical Virology2009，44，： | 1 |
| 15 | BreedingdevelopmentandvarietiesapplicationofPetuniahybridα[J]显示文摘 | YANMX(闫明旭) XIAX(夏询) GUOYL(郭余龙) etal | | 西南园艺0，，： | 1 |
| 16 | Body mass index and risk of breast cancer: a nonlinear dose-response meta-analysis of prospective studies显示文摘 | XiaX ChenW LiJ | 2014 | Sci Rep2014，4，： | 1 |
| 17 | Role of H202 dynamics in brassinosteroid-induced stomata| closure and opening in Solanum lycopersicum 显示文摘 | XiaX J GaoC J SongLX ZhouY H ShiK Yu JQ | 2014 | Plant Cell Environment2014，37，3： | 1 |
| 18 | Nitrousoxideemissionsfromdominatedzonesinashallowlake 显示文摘 | YangZF ZhaoY XiaX H | 2012 | Environmental Pollution2012，166，： | 1 |
| 19 | Effects of chemical foaming agents on the physieo-meehanical properties and theological behavior of bamboo powder-polypropylene foaming composites显示文摘 | Zhou Xiaxing Chen Lihui Lin Qiaojia | 2012 | BioResources2012，7，2： | 1 |
| 20 | Hollownickelnanocornarraysasthree-dimensionalandconductivesupportformetalox-idestoboostsupercapacitiveperformance显示文摘 | CHAOD XIAX ZHUC etal | 2014 | Nanoscale2014，6，11： | 1 |
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