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64篇 您的检索式:作者名="Wordinger"
    题名 作者 年代 出处 被引量
1开角型青光眼降眼压药物的新靶点研究显示文摘青光眼是我国及全球主要的致盲眼病。目前开角型青光眼的治疗局限于通过降低眼压延缓视神经病变的进展。临床用于降低眼压的药物主要机制为增强葡萄膜巩膜通路的房水外流和抑制房水生成。由于青光眼眼压升高的主要原因是小梁网通路阻力上升,因此现有药物未能从根本上纠正疾病的起源和病理生理改变。本文对直接针对青光眼小梁网房水外流阻塞病理机制的新药物靶点和治疗策略进行综述,以期这些新药物靶点和策略成为治疗青光眼的突破性新方法。毛伟明 刘扬 Robert J. Wordinger Abbot F. Clark 彭玉豪 2016中华眼科杂志2016,52,6:5
2Bone morphgenetic protein 4 inhibits TGF-Beta2 stimulation of extracellular matrix proteins in optic nerve head cells:Role of gremlin in ECM modulation显示文摘Zode G S Clark A F Wordinger R J 2009Glia2009,57,7:1
3Glutamate stimulates neurotrophin expression in cultured Miiller cells显示文摘Taylor S Srinivasan B Wordinger R J Roque RS 0,,01:1
4Cultured human trabecular meshwork cells express functional growth factor receptors显示文摘Wordinger RJ Clark AF Agarwal R 1998Invest Ophthalmol Vis Sci1998,39,9:1
5Implantation, deciduoma formation and live births in mast cell deficient mice (W/Wv)显示文摘Wordinger RJ Jackson FL Morrill A 1999Biol Reprod1999,68,2:1
6Cultured human trabecular meshwork cells express functional growth factor receptors 显示文摘Wordinger R J Clark AF Agarwal R 1998Invest Ophthalmol Vis Sci1998,39,9:1
7et al Cultured human trabecular meshwork cells express functional growth factor receptors显示文摘Wordinger RJ Clark AF Agarwal R 1998Invest Ophthalmol Vis Sci1998,39,9:1
8Transforming growth factor-beta2 utilizes the canonical Smad-signaling pathway to regulate tissue transglutaminase expression in human trabecular meshwork cells显示文摘Tovar-Vidales T Clark AF Wordinger RJ 2011Exp Eye Res2011,93,4:1
9Effects of TGF-beta2, BMP-4, and gremlin in the trabecular meshwork: implications for glaucoma 显示文摘Wordinger R J Fleenor DL Hellberg PE 2007Invest Ophthalmol Vis Sci2007,48,3:1
10The immunolocalization of basic fibroblast growth factor in the mouse uterus during the initial stage of embryo implantation显示文摘 Smith KJ Bell C 1994Growth Factor1994,11,2:1
11Cultured human trabecular meshwork cells express functional growth factor receptors显示文摘Wordinger RJ Clark AF Agarwal R 0,,09:1
12Effects of glucocorticoids on the trabecular meshwork: towards a better understanding of glaucoma 显示文摘Wordinger RJ Clark AF 1999Prog Retinal Eye Res1999,18,5:1
13The Fas-Fas ligand system and other modulators of apoptosis in the cornea显示文摘Wilson SE Li Q Weng J Barry-Lane PA Jester JV Liang Q Wordinger RJ 1996Invest Ophthalmol Vis Sci1996,37,8:1
14Focus on molecules:s FRP1显示文摘Mao W Wordinger RJ Clark AF 2010Experimental Eye Research2010,91,5:1
15Bone morphogenetic proteins and their receptors in the eye显示文摘Wordinger ILl Clark AF 2007ExpBiol Med2007,232,8:1
16Cultured human trabecular meshwork cells express functional growth factor receptors显示文摘WORDINGER R J CLARK A F AGARWAL R 0,,09:1
17Effects of TGF- beta2, BMP-4, and gremlin in the trabecular meshwork: implications for glaucoma显示文摘Wordinger RJ Fleenor DL Hellberg PE 2007Invest Ophthalmal Vis Sci2007,48,3:1
18Expression of ciliary neurotrophic factor (CNTF) and its tripartite receptor complex by cells of the human optic nerve head显示文摘 Clark AF Wordinger RJ 2007Mol Vis2007,23,13:1
19Glutamate stimulates neurotrophin expression in cultured Müller cell显示文摘TAYLOR S SRINIVASAN B WORDINGER R J 2003Brain Res Mol Brain Res2003,111,12:1
20Transforming growthfactor-beta2 utilizes the canonical Smad-signaling pathway toregulate tissue transglutaminase expression in human trabecularmeshwork cells 显示文摘Tovar-Vidales T Clark AF Wordinger RJ 2011Exp Eye Res2011,93,44:1
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