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| 1 | Coordinated peak expression of MMP-26 and TIMP-4 in preinvasive human prostate tumor显示文摘因为早察觉和治疗为病人的医药管理是批评的,为早前列腺癌症诊断的新奇简历标记的鉴定是高度重要的。在基础房间层和地下室膜的连续性的混乱为高级职业人员静电干扰 intraepithelial 瘤形成(HGPIN ) 的前进是必要的到在人的前列腺的侵略腺癌。涉及变换到侵略显型的分子是强烈审查的题目。我们以前报导了矩阵 metalloproteinase-26 (MMP-26 ) 经由地下室膜蛋白质并且由激活 MMP-9 的酶原形式的劈开支持人的前列腺癌症房间的侵略。而且,我们发现了 metalloproteinases-4 (TIMP-4 ) 的那个织物禁止者是大多数有势力 MMP-26 的内长的禁止者。这里,我们更高示威(p<0.0001 ) 在 HGPIN 和癌症的 MMP-26 和 TIMP-4 表示,与非肿瘤的 acini 相比。他们的表示层次在 HGPIN 是最高的,但是在一样的纸巾在侵略癌症(为各个的 p<0.001 ) 衰退。连续前列腺癌症织物节染色的 Immunohistochemical 建议 MMP-26 和 TIMP-4 的 colocalization。现在的学习显示 MMP-26 和 TIMP-4 可以在 HGPIN 的变换期间起一个不可分的作用到侵略癌症并且可以也为早前列腺癌症诊断用作标记。房间研究(2006 ) 16:750-758。做 i:10.1038/sj .cr.7310089;出版联机 2006 年 8 月 29 日。 | Seakwoo Lee Kevin K Desai Kenneth A Iczkowski Robert G Newcomer Kevin J WU Yun-Ge Zhao Winston W Tan Mark D Roycik Qing-Xiang Amy Sang | 2006 | Cell Research2006，16，9： | 18 |
| 2 | A history of high-power laser research and development in the United Kingdom显示文摘The first demonstration of laser action in ruby was made in 1960 by T.H.Maiman of Hughes Research Laboratories,USA.Many laboratories worldwide began the search for lasers using different materials,operating at different wavelengths.In the UK,academia,industry and the central laboratories took up the challenge from the earliest days to develop these systems for a broad range of applications.This historical review looks at the contribution the UK has made to the advancement of the technology,the development of systems and components and their exploitation over the last 60 years. | Colin N.Danson Malcolm White John R.M.Barr Thomas Bett Peter Blyth David Bowley Ceri Brenner Robert J.Collins Neal Croxford A.E.Bucker Dangor Laurence Devereux Peter E.Dyer Anthony Dymoke-Bradshaw Christopher B.Edwards Paul Ewart Allister I.Ferguson John M.Girkin Denis R.Hall David C.Hanna Wayne Harris David I.Hillier Christopher J.Hooker Simon M.Hooker Nicholas Hopps Janet Hull David Hunt Dino A.Jaroszynski Mark Kempenaars Helmut Kessler Sir Peter L.Knight Steve Knight Adrian Knowles Ciaran L.S.Lewis Ken S.Lipton Abby Littlechild John Littlechild Peter Maggs Graeme P.A.Malcolm OBE Stuart P.D.Mangles William Martin Paul McKenna Richard O.Moore Clive Morrison Zulfikar Najmudin David Neely Geoff H.C.New Michael J.Norman Ted Paine Anthony W.Parker Rory R.Penman Geoff J.Pert Chris Pietraszewski Andrew Randewich Nadeem H.Rizvi Nigel Seddon MBE Zheng-Ming Sheng David Slater Roland A.Smith Christopher Spindloe Roy Taylor Gary Thomas John W.G.Tisch Justin S.Wark Colin Webb S.Mark Wiggins Dave Willford Trevor Winstone | 2021 | High Power Laser Science and Engineering2021，9，2： | 5 |
| 3 | GISAID’s Role in Pandemic Response显示文摘GISAID is a global data science initiative and the primary source of genomic and associated metadata of all influenza viruses,Respiratory Syncytial Virus(RSV)and severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),the pandemic coronavirus causing coronavirus disease 2019(COVID-19).GISAID’s publicly accessible data sharing platform enables collaboration of over 42,000 participating researchers from 198 nations and data generators from over 3,500 institutions across the globe.Since the first wholegenome sequences were made available by China CDC through GISAID on January 10. | Shruti Khare Céline Gurry Lucas Freitas Mark B Schultz Gunter Bach Amadou Diallo Nancy Akite Joses Ho Raphael TC Lee Winston Yeo GISAID Core Curation Team Sebastian Maurer-Stroh | 2021 | China CDC weekly2021，3，49： | 3 |
| 4 | Reference and Information Services for Young Adults显示文摘 | Winston Mark Kimberly Lione Paone | 2001 | Reference & User Services Quarterly2001，41，1： | 1 |
| 5 | Leadership Education for Young Adult Librarians:A Research Study 显示文摘 | Winston Mark D Fisher Deborah | 2003 | Public Library Quarterly2003，22，03： | 1 |
| 6 | Worker honey bee ovary development: seasonal variation and the influence of larval and adult nutrition显示文摘 | Shelley E. R. Hoover Heather A. Higo Mark L. Winston | 2006 | Journal of Comparative Physiology B2006，，1： | 1 |
| 7 | A biopsy simulation study to assess the accuracy of several transrectal ultrasonography (TRUS)‐biopsy strategies compared with template prostate mapping biopsies in patients who have undergone radical prostatectomy显示文摘 | Yipeng Hu Hashim U. Ahmed Tim Carter Nimalan Arumainayagam Emilie Lecornet Winston Barzell Alex Freeman Pierre Nevoux David J. Hawkes Arnauld Villers Mark Emberton Dean C. Barratt | 2012 | BJU International2012，，6： | 1 |
| 8 | Honey bee colony mortality and productivity with single and dual infestations of parasitic mite species显示文摘 | Danielle L Downey Mark L Winston | 2001 | Apidologie2001，32，： | 1 |
| 9 | The influence of a queen-produced substance, 9HDA, on swarm clustering behavior in the honeybeeApis mellifera L.显示文摘 | Mark L. Winston Keith N. Slessor Michael J. Smirle Ali A. Kandil | 1982 | Journal of Chemical Ecology1982，，10： | 1 |
| 10 | Sentinel node biopsy in breast cancer显示文摘 | John M. Barnwell MD Mark A. Arredondo MD Daniel Kollmorgen MD John F. Gibbs MD Dominick Lamonica MD William Carson MD Paul Zhang MD Janet Winston MD Stephen B. Edge MD | 1998 | Annals of Surgical Oncology1998，，2： | 1 |
| 11 | C-Reactive Protein, a Sensitive Marker of Inflammation, Predicts Future Risk of Coronary Heart Disease in Initially Healthy Middle-Aged Men: Results From the MONICA (Monitoring Trends and Determinants in Cardiovascular Disease) Augsburg Cohort Study, 1984显示文摘 | Wolfgang Koenig Malte Sund Margit Frohlich Hans-Gunther Fischer Hannelore Lowel Angela Doring Winston L. Hutchinson Mark B. Pepys | 1999 | Circulation1999，，2： | 1 |
| 12 | Crystal structure of a decameric comp lex of human serum amyloid P component with bound damp显示文摘 | ERHARD HOHENESTER WINSTON L HUTCHINSON MARK B | 1997 | Mol Biol1997，269，： | 1 |
| 13 | 非洲化蜜蜂的生物学特性和管理显示文摘非洲化蜜蜂的生物学特性和管理MarkL.Winston前言非洲化蜜蜂是非洲蜜蜂和欧洲蜜蜂自然杂交形成的种群。自从1956年南美洲引入非洲化蜜蜂以来,其在拉丁美洲扩散速度很快,分布密集。非洲化蜜蜂已经给养蜂业带来了很大损失,常造成人畜伤亡事故,因而称之... | Mark L. Winston 郭冬生 | 1997 | 养蜂科技1997，，4： | 0 |
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