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| 1 | Culture of yeast cells immobilized by alginate-chitosan microcapsules in aqueous-organic solvent biphasic system显示文摘Immobilization biocatalysis is a potential technology to improve the activity and stability of biocatalysts in nonaqueous systems for efficient industrial production.Alginate-chitosan(AC)microcapsules were prepared as immobilization carriers by emulsifi cation-internal gelation and complexation reaction,and their contribution on facilitating the growth and metabolism of yeast cells were testifi ed successfully in culture medium-solvent biphasic systems.The cell growth in AC microcapsules is superior to that in alginate beads,and the cells in both immobilization carriers maintain much higher activity than free cells,which demonstrates AC microcapsules can confer yeast cells the ability to resist the adverse effect of solvent.Moreover,the performance of AC microcapsules in biphasic systems could be improved by adjusting the formation of outer polyelectrolyte complex(PEC)membrane to promote the cell growth and metabolic ability under the balance of resisting solvent toxicity and permitting substrate diffusion.Therefore,these findings are quite valuable for applying AC microcapsules as novel immobilization carriers to realize the biotransformation of value-added products in aqueous-solvent biphasic systems. | HOU Dandan YU Weiting ZHANG Demeng ZHAO Lili LIU Xiudong MA Xiaojun | 2019 | Journal of Oceanology and Limnology2019，37，3： | 4 |
| 2 | Preparation of protein-loaded microspheres with size ≤ 10 μm by electrostatic droplet generation technology显示文摘The development of non-injection route for protein drugs, especially oral administration, has been the main focus of controlled release of drugs. To overcome obstacles unsolved such as enzyme degradation and penetration barrier of intestinal epi- thelium, technologies using microspheres as carrier of protein drugs have been proven potential to realize oral administration. It has been demonstrated that microspheres can not only protect proteins, but also facilitate the penetration and absorption through Peyer’s patches when the size is smaller than 10 μm. Therefore, the objective of this paper is to prepare protein-loaded microspheres with size ≤ 10 μm. Electrostatic droplet generation technology was used with insulin and hemoglobin as drug models and so- dium alginate as microsphere material. By decreas- ing the surface tension of feed solution by adding surfactant, and improving electric field distribution by changing the shape of container and electrode for gelation solution, protein-loaded microspheres with mean size less than 10 μm were successfully pro- duced through needle with diameter of 400 μm. The microspheres showed good sphericity and narrow size distribution. The mean standard variance of size distribution was 1.61. The encapsulation efficiency of proteins was over 70%. Moreover, the significance analysis of factors influencing the size of protein loaded microspheres was carried out through or- thogonal experiments, which showed that output voltage (U), needle diameter (D) and the distance between needle tips to the surface of gelation solu- tion (δ ) influenced significantly the size of micro-spheres. Finally, the statistic analysis showed that when confidence level was α=0.05, and α=0.1, con- fidence interval of microsphere size can be (6.2545, 10.1735) and (6.6022, 9.8258) correspondingly, suggesting that there is good repeatability and reli- ability for improving electrostatic droplet generation technology to prepare protein-loaded microspheres with size ≤10 μm. | XUE Weiming LIU Xiudong YU Weiting MA Xiaojun | 2006 | Chinese Science Bulletin2006，51，3： | 3 |
| 3 | Amphiphilic sodium alginate-vinyl acetate microparticles for drug delivery显示文摘To overcome the fast or burst release of hydrophilic drugs from hydrophilic alginate-based carriers,hydrophobic molecule(vinyl acetate,VAc)was grafted on alginate(Alg),which was further used to prepare drug carriers.Amphiphilic Alg-g-PVAc hydrogel beads were firstly prepared by emulsification/internal gelation technique for the loading of bovine serum albumin(BSA).Then,chitosan was coated on the surface of beads to form novel amphiphilic Alg-g-PVAc/chitosan(Alg-g-PVAc/CS)microcapsules.The BSA-loading amphiphilic Alg-g-PVAc/chitosan(Alg-g-PVAc/CS)microcapsules display similar morphology and size to the hydrophilic alginate/chitosan(AC)microcapsules.However,the drug loading and loading efficiency of BSA in Alg-g-PVAc/CS microcapsules are higher,and the release rate of BSA from Alg-g-PVAc/CS microcapsules is slower.The results demonstrate that the introduction of hydrophobic PVAc on alginate can effectively help retard the release of BSA,and the higher degree of substitution is,the slower the release rate is.In addition,the complex membrane can also be adjusted to delay the release of BSA.As a whole,amphiphilic sodium alginate-vinyl acetate/CS microparticles could be developed for macromolecular drug delivery. | YU Weiting ZHANG Demeng LIU Xiudong WANG Yunhong TONG Jun ZHANG Mengxue MA Xiaojun | 2019 | Journal of Oceanology and Limnology2019，37，3： | 2 |
| 4 | Measuring complexity using Fuzzy En,Ap En,and Samp En显示文摘 | Chen Weiting Zhuang Jun Yu Wangxin | 2009 | Medical Engineering&Physics2009，31，1： | 1 |
| 5 | Quantitative characterization of membrane formation process of alginate-chitosan microcapsules by GPC显示文摘 | Weiting Yu Junzhang Lin Xiudong Liu | 2010 | Journal of Membrane Science2010，346，： | 1 |
| 6 | Effects of oligochitosans on tobacco cells and role of endogenous nitric oxide burst in the resistance of tobacco to Tobacco mosaic virus显示文摘 | Zhao Xiaoming She Xiaoping Yu Weiting | 2007 | Journal of Plant Pathology2007，89，1： | 1 |
| 7 | Thermal effects on fracture toughness of cracked straight-through Brazilian disk green sandstone and granite显示文摘Cracked straight-through Brazilian disc(CSTBD) samples prepared using two rock materials were used for thermal treatment from room temperature to 700℃. Uniaxial splitting experiments were performed using an automatic electro-hydraulic servo press to study the evolution laws of physical and fracture properties of different deep rock materials under high-temperature geological conditions. The fracture characteristics were measured using an industrial camera and digital image correlation technology to analyze the effect of high temperature on fracture properties and failure modes of the CSTBD samples after different thermal treatments. The micro-damage properties of green sandstone and granite materials were obtained using a scanning electron microscope(SEM). The following conclusions were drawn from the test results:(1) With the increasing temperature, the fracture characteristics of green sandstone and granite change from brittle fracture to plasticity fracture, the longitudinal wave velocity of granite decreases sharply at 600℃, and the damage factor reaches 0.8748 at 700℃.(2) The fracture toughness of green sandstone and granite decreases with increasing temperature;however, the decreasing range of granite is larger than that of green sandstone.(3) As the temperature increases, the fracture morphologies of green sandstone and granite materials become rougher, whereas thermal damage cracks of granite and intergranular fractures inside sandstone as well as pores of sandstone increase.(4) The crack tip opening displacement and peak strain corresponding to peak load increase with the temperature. | Lei Zhou Weiting Gao Liyuan Yu Zheming Zhu Jianxing Chen Xingkai Wang | 2022 | Journal of Rock Mechanics and Geotechnical Engineering2022，14，5： | 1 |
| 8 | A new framework to combine vertical and horizontal information for face recognition 显示文摘 | Yu Wangxin Wang Zhizhong Chen Weiting | 2009 | Neurocomputing2009，72，46： | 1 |
| 9 | Microencapsulated probiotics using emulsification technique coupled with internal or external gelation process显示文摘 | Huiyi Song Weiting Yu Meng Gao Xiudong Liu Xiaojun Ma | 2013 | Carbohydrate Polymers2013，，1： | 1 |
| 10 | Toughening Effects through Optimizing Cell Structure and Deformation Behaviors of Al–Mg Foams显示文摘As widely used protective materials,the application of Al foams is still limited by their low intrinsic mechanical properties caused by the brittleness of struts.The introduction of Mg is recently demonstrated effective to improve the mechanical performance of Al foams;however,the mechanism of Mg modification is still not clear.In this work,Al-Mg foams are developed through a powder metallurgy process with excellent compression performance and high energy absorption capacity.The effects of Mg modification on the cell structure,toughness,and deformation behavior are investigated systematically.As a result,the small cell size of~1.8 mm and the high sphericity of 0.92 are achieved with 5% of Mg addition,delivering high compression stress of 8.5±0.43 MPa and energy absorption capacity of 6.9±0.36 MJ/m^(3),simultaneously.The synergistic mechanism for the improved mechanical performance is also demonstrated to be the combination of stress transfer and plastic deformation behavior of cells.The results provide a new strategy to develop high-performance foam materials by improving toughness and further promote the practical application. | Hao Yu Xudong Yang Weiting Li Xudong Rong Siyuan Guo Lishi Ma Lizhuang Yang Junwei Sha Naiqin Zhao | 2022 | Acta Metallurgica Sinica(English Letters)2022，35，12： | 1 |
| 11 | Kinetic Adsorption of Cd onto Nanometer Al_2O_3/Carbon Fibre显示文摘A new nanometer material, nano-Al2O3 with carbon fibre as the carrier, was employed for the removal of Cd with low concentrations from polluted water. The characterization of the material was carried out by means of SEM and TEM. Batch adsorption and elution experiments were carried out to determine the adsorption properties of Cd on the new adsorbent. The classical Thomas model was applied to estimating the equilibrium coefficients of Cd adsorption and the saturated adsorption ability. The results show that the Thomas model is fit for describing the kinetic adsorption process, and the maximum adsorption capacity of the nanometer Al2O3/carbon is 69.29 mg/g. The resulting information also indicates that the desorption of Cd eluted with de-ionized water at a rate of 9.8 mL/min can be neglected. With the advantage of a high adsorption capacity for removing low concentration Cd, the Al2O3/carbon fibre possesses the potentiality to be an effective adsorbent for the removal of Cd from polluted water. | LI Yu WANG Yue HAN Weit LI Su-wen ZHAO Hui ZHU Chang-yun WANG Heng | 2005 | Chemical Research in Chinese Universities2005，21，5： | 1 |
| 12 | Measuring complexity using FuzzyEn ApEn and SampEn 显示文摘 | Chen Weiting Zhuang Jun Yu Wangxin | 2009 | Medical Engi- neering and Physics2009，31，1： | 1 |
| 13 | Measur- ing complexity using FuzzyEn, ApEn, and SampEn显示文摘 | CHEN WEITING ZHUANG JUN YU WANGXIN | 2009 | Medical Engineering & Physics2009，31，1： | 1 |
| 14 | Synthesis of yttrium iron garnet using polymer-metal chelate precursor显示文摘 | Wang Chengchen Yu Weiting | 2007 | Journal of Colloid and Interface Science2007，306，2： | 1 |
| 15 | Novel use of PVPP in a modified Qu ECh ERS extraction method forUPLC-MS/MS analysis of neonicotinoid insecticides in tea matrices显示文摘 | HOU Ruyan JIAO Weiting XIAO Yu | 2015 | Anal2015，7，： | 1 |
| 16 | Measuring complexity using FuzzyEn, ApEn, and SampEn 显示文摘 | Chen Weiting Zhang Jun Yu Wangxin | 2009 | Medical Engineering & Physics2009，31，1： | 1 |
| 17 | Behavior of microbial growth and metabolism in alginate-chitosan-alginate (ACA) microcapsules 显示文摘 | Qi Wentao Ma Juan Yu Weiting | 2006 | Enzyme Microb Technol2006，38，： | 1 |
| 18 | A new framework to combine vertical and horizontal information for face recognition显示文摘 | YU Wangxin WANG Zhizhong CHEN Weiting | 2009 | Neurocomputing2009，72，： | 1 |
| 19 | Sodium alginate-chitosan composite membrane performance of oxygendiffusion in research显示文摘 | Zhao Wei Zhang Ying Yu Weiting | 2012 | J Chem Eng of Chinese Univ2012，26，3： | 1 |
| 20 | A New Framework to Combine Vertical and Horizontal Information for Face Recognition显示文摘 | Yu Wangxin Wang Zhizhong Chen Weiting | 2009 | Neurocomputing2009，72，46： | 1 |
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