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| 1 | Reinforcement learning based parameter optimization of active disturbance rejection control for autonomous underwater vehicle显示文摘This paper proposes a liner active disturbance rejection control(LADRC) method based on the Q-Learning algorithm of reinforcement learning(RL) to control the six-degree-of-freedom motion of an autonomous underwater vehicle(AUV).The number of controllers is increased to realize AUV motion decoupling.At the same time, in order to avoid the oversize of the algorithm, combined with the controlled content, a simplified Q-learning algorithm is constructed to realize the parameter adaptation of the LADRC controller.Finally, through the simulation experiment of the controller with fixed parameters and the controller based on the Q-learning algorithm, the rationality of the simplified algorithm, the effectiveness of parameter adaptation, and the unique advantages of the LADRC controller are verified. | SONG Wanping CHEN Zengqiang SUN Mingwei SUN Qinglin | 2022 | Journal of Systems Engineering and Electronics2022，33，1： | 1 |
| 2 | A Novel Anti-Human Syndecan-1 (CD138) Monoclonal Antibody 4B3: Characterization and Application显示文摘Syndecan-1 (CD138), a member of integral membrane heparin sulfate proteoglycans, is an essential matrix receptor for maintaining the normal morphological phenotypes. In this study, we generated a specific mouse anti-human syndecan-1 monoclonal antibody (mAb) 4B3 and identified it by competition assay with the available syndecan-1 mAb (BB4). Stained by 4B3, the expression of syndecan-1 was detected on tumor cell lines, such as 8226, U266, XG-1, XG-2, Daudi and Jurkat. The expression was also found on neuron stem cells. It was established that 4B3 mAb could inhibit XG-1 and XG-2 proliferation. The data not only determined that 4B3 mAb was a functional anti-human syndecan-1 mAb, but also indicated that syndecan-1 might be a valuable surface antigen and play an important role in regulation of tumor pathology and differentiation of neural stem cells. This novel antibody 4B3 may be value of study of tumor proliferation/survival mechanism and contributes to diagnosis and treatment of diverse diseases. | Wanping Sun Fengming Wang Fang Xie Guoqing Wang Jin Sun Gehua Yu Yuhua Qiu Xueguang Zhang | 2007 | Cellular & Molecular Immunology2007，4，3： | 1 |
| 3 | Magnetism variation of the compressed antiferromagnetic topological insulator EuSn_(2)As_(2)显示文摘We report a comprehensive high-pressure study,up to 21.1 GPa,on the antiferromagnetic topological insulator EuSn_(2)As_(2) achieved through synchrotron X-ray diffraction,Raman scattering,electrical resistance,magnetic resistance,and Hall transport measurements in combination with first-principles calculations.The Néel temperatures determined from resistance are increased from(24±1)to(77±8)K under pressure,which is a result of enhanced magnetic exchange couplings between Eu^(2+) ions yielded by our first-principles calculations.The negative magnetoresistance of EuSn_(2)As_(2) persists to higher temperatures accordingly.However,the enhancement of the observed Néel temperatures deviates from the calculations above 10.0 GPa.In addition,the magnitude of the magnetoresistance,Hall coefficients,and charge carrier densities show abrupt changes between 6.9 and 10.0 GPa.The abrupt changes likely originate from a pressure-induced valence change of Eu ions from a divalent state to a divalent and trivalent mixed state or are related to the structural transition revealed by Raman scattering measurements.Our results provide insight into magnetism variation in EuSn_(2)As_(2) and similar antiferromagnetic topological insulators under pressure. | Hualei Sun Cuiqun Chen Yusheng Hou Weiliang Wang Yu Gong Mengwu Huo Lisi Li Jia Yu Wanping Cai Naitian Liu Ruqian Wu Dao-Xin Yao Meng Wang | 2021 | Science China(Physics,Mechanics & Astronomy)2021，64，11： | 0 |
| 4 | An ancient whole-genome duplication event and its contribution to flavor compounds in the tea plant (Camellia sinensis)显示文摘Tea,coffee,and cocoa are the three most popular nonalcoholic beverages in the world and have extremely high economic and cultural value.The genomes of four tea plant varieties have recently been sequenced,but there is some debate regarding the characterization of a whole-genome duplication(WGD)event in tea plants.Whether the WGD in the tea plant is shared with other plants in order Ericales and how it contributed to tea plant evolution remained unanswered.Here we re-analyzed the tea plant genome and provided evidence that tea experienced only WGD event after the core-eudicot whole-genome triplication(WGT)event.This WGD was shared by the Polemonioids-Primuloids-Core Ericales(PPC)sections,encompassing at least 17 families in the order Ericales.In addition,our study identified eight pairs of duplicated genes in the catechins biosynthesis pathway,four pairs of duplicated genes in the theanine biosynthesis pathway,and one pair of genes in the caffeine biosynthesis pathway,which were expanded and retained following this WGD.Nearly all these gene pairs were expressed in tea plants,implying the contribution of the WGD.This study shows that in addition to the role of the recent tandem gene duplication in the accumulation of tea flavor-related genes,the WGD may have been another main factor driving the evolution of tea flavor. | Ya Wang Fei Chen Yuanchun Ma Taikui Zhang Pengchuan Sun Meifang Lan Fang Li Wanping Fang | 2021 | Horticulture Research2021，8，1： | 0 |
| 5 | Recognition for avian influenza virus proteins based on support vector machine and linear discriminant analysis显示文摘Total 200 properties related to structural characteristics were employed to represent structures of 400 HA coded proteins of influenza virus as training samples. Some recognition models for HA proteins of avian influenza virus (AIV) were developed using support vector machine (SVM) and linear discriminant analysis (LDA). The results obtained from LDA are as follows: the identification accuracy (Ria) for training samples is 99.8% and Ria by leave one out cross validation is 99.5%. Both Ria of 99.8% for training samples and Ria of 99.3% by leave one out cross validation are obtained using SVM model, respectively. External 200 HA proteins of influenza virus were used to validate the external predictive power of the resulting model. The external Ria for them is 95.5% by LDA and 96.5% by SVM, respectively, which shows that HA proteins of AIVs are preferably recognized by SVM and LDA, and the performances by SVM are superior to those by LDA. | LIANG GuiZhao CHEN ZeCong YANG ShanBin MEI Hu ZHOU Yuan YANG Li ZHOU Peng YANG ShengXi SHU Mao LIAO ChunYang WU ShiRong LI GenRong HE Liu GAO JianKun Gan MengYu LI DeJing CHEN GuoPing WANG GuiXue LONG Sha JING JuHua ZHENG XiaoLin ZENG Hui ZHANG QiaoXia ZHANG MengJun YANG Qi TIAN FeiFei TONG JianBo WANG JiaoNa LIU YongHong LI Bo QIU LiangJia CAI ShaoXi ZHAO Na YANG Yan SU XiaLi SONG Jian CHEN MeiXia ZHANG XueJiao SUN JiaYing LI JingWei CHEN GuoHua CHEN Gang DENG Jie PENG ChuanYou ZHU WanPing XU LuoNan WU YuQuan LIAO LiMin LI Zhi LI Jun LU DaJun SU QinLiang HUANG ZhengHu ZHOU Ping LI ZhiLiang | 2008 | Science China Chemistry2008，51，2： | 0 |
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