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| 1 | Improvement of center segregation in high-carbon steel billets using soft reduction显示文摘Center segregation is the main reason for cup fracture of high-carbon wire rod during drawing. Therefore, to continuously produce cast billets with very low center segregation is an important objective. The soft reduction technology is considered to be an effective method to minimize center segregation. To elucidate the effect of soft reduction on the internal quality of high-carbon steel billets, soft reduction was applied with different solid fractions in the core area of billets in a laboratory casting machine. A coupled temperature/displacement finite element model was developed to calculate the solid fraction using the commercial software ABAQUS.Center segregation, center porosity, homogeneity of elements, and equiaxed crystal zone were obviously improved by applying soft reduction, especially when the solid fraction was less than 1.0. The optimal results were obtained when the solid fraction was approximately 0.9. | Wenjun Wang Xionggang Hu Linxin Ning Raimund Bülte Wolfgang Bleck | 2006 | Journal of University of Science and Technology Beijing2006，13，6： | 5 |
| 2 | Microstructure and Mechanical Properties of Mg–3Al–Zn Magnesium Alloy Sheet by Hot Shear Spinning显示文摘Hot shear spinning experiments with Mg–3.0 Al–1.0 Zn–0.5 Mn(AZ31 B, wt%) magnesium alloy sheets were conducted at various temperatures, spindle speeds and feed ratios to investigate the effects of these processing parameters on the microstructure, crystallographic texture and mechanical properties. The AZ31 B sheet displayed good shear formability at temperatures from 473 to 673 K, spindle speeds from 300 to 600 rev/min and feed ratios from 0.1 to 0.5 mm/rev. During the dynamic recrystallization process, the grain size and texture were affected by the deformation temperature of the hot shear spinning process. Each of the spun sheets presented a strong basal texture, and the c-axis of most of the grains was parallel to the normal direction. The optimal hot shear spinning parameters were determined to be a temperature of 473 K, a spindle speed of 300 rev/min and a feed ratio of 0.1 mm/rev. The yield strength, ultimate tensile strength and elongation in the rolled direction reached 221 MPa, 288 MPa and 14.1%, and those in the transverse direction reached 205 MPa, 280 MPa and 12.4%, respectively. The improved strength and decreased mechanical anisotropy resulted from the fine grain size and strong basal texture. | Fenghua Wang Peng Su Linxin Qin Shuai Dong Yunliang Li Jie Dong | 2020 | Acta Metallurgica Sinica(English Letters)2020，33，9： | 4 |
| 3 | miR-7/TGF-β2 axis sustains acidic tumor microenvironment-induced lung cancer metastasis显示文摘Acidosis,regardless of hypoxia involvement,is recognized as a chronic and harsh tumor microenvironment(TME)that educates malignant cells to thrive and metastasize.Although overwhelming evidence supports an acidic environment as a driver or ubiquitous hallmark of cancer progression,the unrevealed core mechanisms underlying the direct effect of acidification on tumorigenesis have hindered the discovery of novel therapeutic targets and clinical therapy.Here,chemical-induced and transgenic mouse models for colon,liver and lung cancer were established,respectively.miR-7 and TGF-β2 expressions were examined in clinical tissues(n=184).RNA-seq,miRNA-seq,proteomics,biosynthesis analyses and functional studies were performed to validate the mechanisms involved in the acidic TME-induced lung cancer metastasis.Our data show that lung cancer is sensitive to the increased acidification of TME,and acidic TME-induced lung cancer metastasis via inhibition of miR-7-5 p.TGF-β2 is a direct target of miR-7-5 p.The reduced expression of miR-7-5 p subsequently increases the expression of TGF-β2 which enhances the metastatic potential of the lung cancer.Indeed,overexpression of miR-7-5 p reduces the acidic p H-enhanced lung cancer metastasis.Furthermore,the human lung tumor samples also show a reduced miR-7-5 p expression but an elevated level of activated TGF-β2;the expressions of both miR-7-5 p and TGF-β2 are correlated with patients’survival.We are the first to identify the role of the miR-7/TGF-β2 axis in acidic p H-enhanced lung cancer metastasis.Our study not only delineates how acidification directly affects tumorigenesis,but also suggests miR-7 is a novel reliable biomarker for acidic TME and a novel therapeutic target for non-small cell lung cancer(NSCLC)treatment.Our study opens an avenue to explore the p H-sensitive subcellular components as novel therapeutic targets for cancer treatment. | Tao Su Suchao Huang Yanmin Zhang Yajuan Guo Shuwei Zhang Jiaji Guan Mingjing Meng Linxin Liu Caiyan Wang Dihua Yu Hiu-Yee Kwan Zhiying Huang Qiuju Huang Elaine Lai-Han Leung Ming Hu Ying Wang Zhongqiu Liu Linlin Lu | 2022 | Acta Pharmaceutica Sinica B2022，12，2： | 2 |
| 4 | Effect of tumor necrosis factor inhibitors on rheumatoid arthritis-induced peripheral neuropathy A cohort study显示文摘In this historical cohort study,236 patients with primary rheumatoid arthritis were treated with the tumor necrosis factor inhibitors,etanercept or infliximab(n = 80),or by conventional methods(n = 156).Results revealed that 11 patients developed varying types of peripheral neuropathy at 1-2 years post-treatment(mean 16 months).The incidence of peripheral neuropathy in the tumor necrosis factor inhibitors treatment group was 8.8%(7/80),which was significantly higher than the conventional treatment group(2.6%;4/156).The relative risk of developing peripheral neuropathy in the tumor necrosis factor inhibitors treatment group was 3.41(95% confidence interval:1.03-11.31).Comparison of the tumor necrosis factor inhibitors revealed that etanercept and infliximab had no significant difference in terms of inducing peripheral neuropathy.Experimental findings indicate that tumor necrosis factor inhibitors may increase the risk of peripheral neuropathy. | Naizhi Wang Yingying Guo Lili Yang Wenyi Fu Yanbing Xu Linxin Hou Shuai Zhao Ning Zhang | 2012 | Neural Regeneration Research2012，7，11： | 2 |
| 5 | On the calibration of continuous, high precision (tsO and (2H measure- ments using off-axis integrated cavity output spectrometer 显示文摘 | WANG Linxin CAYLOR K K DRAGONI D | 2009 | Rapid Commun Mass 5ectrom2009，23，4： | 1 |
| 6 | Microstructure and properties of Nd:YAG laser welded AZ31B magnesium alloy显示文摘 | Cui Zeqin Cheng Linxin Si En Wang Wenxian Xu Bingshe | 2014 | China Welding2014，23，2： | 1 |
| 7 | Formation of internal cracks in steel billets during soft reduction显示文摘To investigate the formation of internal cracks in steel billets during soft reduction, fully coupled thermo-mechanical finite element models were developed using the commercial software ABAQUS, also casting and soft reduction tests were carried out in a laboratory strand casting machine. With the finite element models, the temperature distribution, the stress and strain states in the bil-let were calculated. The relation between internal cracks and equivalent plastic strain, as well as maximal principal stress was ana-lyzed. The results indicate that tensile stresses can develop in the mushy zone during soft reduction and the equivalent strain nearby the zero ductility temperature (ZDT) increases with decreasing solid fraction. Internal cracks can be initiated when the accumulated strain exceeds the critical strain or the applied tensile stress exceeds the critical fracture stress during solidification. | Wenjun Wang Linxin Ning Raimund Biilte Wolfgang Bleek | 2008 | Journal of University of Science and Technology Beijing2008，15，2： | 1 |
| 8 | Direct quantification of leaf transpiration isotopic composition 显示文摘 | WANG Linxin GOOD S P CAYLOR K K | 2012 | Agric For Meteorol2012，154，： | 1 |
| 9 | Minimum CDS inmultihop wireless networks with disparate communicationranges 显示文摘 | Wang Linxin Wan Pengjun Yao Frances | 2013 | IEEE Trans on Mobile Computing2013，12，5： | 1 |
| 10 | Cluster and characteristic analysis of Shanghai metro stations based on metro card and land-use data显示文摘Metro is an important form of public transport in Shanghai.Based on the metro card data,we conduct the cluster analysis of Shanghai metro stations according to the pattern of passenger flow changing with time.Then the characteristics of travel time and surrounding land use are investigated for different types of stations to explore the relationship between urban land-use characteristics and travel activities reflected by passenger flow at metro stations.It is found that the passenger flow pattern of metro stations is closely related to the location conditions of stations and its surrounding land-use patterns.Based on various characteristics,285 metro stations are classified into four types,including residential-oriented stations,employmentoriented stations,employment-residence-oriented stations,and integrated functionaloriented stations,reflecting the interaction between spontaneous travel behavior and urban land-use characteristics and providing a reference for optimizing the urban functional structure and the spatial allocation of facilities. | Ping Shen Linxin Ouyang Chong Wang Yin Shi Yiheng Su | 2020 | Geo-Spatial Information Science2020，23，4： | 1 |
| 11 | Synthesis of poly(pyridine-imide)s and their electronic memory performances显示文摘In this paper,poly(pyridine-imide)s,PI-Ph and PI-Naphth,were successfully synthesised and fabricated for use as memory devices.The Al/PI-Ph/indium tin oxide(ITO)device showed dynamic random access memory characteristics,whereas Al/PI-Naphth/ITO showed rewritable(FLASH)memory characteristics.Characterisation of their UV,cyclic voltammograms,and density functional theory,were used to illustrate the different memory behaviours.The results show that the stability of electric-field-induced-charge-transfer complexes can affect memory performance. | Haifeng Chen Linxin Wu Xiong Xiao Hongliang Wang Jun Jiang Lihua Wang Qingfeng Xu Jianmei Lu | 2017 | Science China Chemistry2017，60，2： | 1 |
| 12 | Improvement of center segregation in high-carbon steel billets using soft reduetion 显示文摘 | WANG Wenjun HU Xianggang NING Linxin | 2006 | Journal of University of Seienee and Teehnology Beijing2006，13，6： | 1 |
| 13 | Quaternized chitosan-assisted in situ synthesized CuS/cellulose nanofibers conductive paper for flexible electrode显示文摘Cellulose nanofibers(CNF)are considered to be a potential substrate of energy material for energy storage devices due to the foldable,lightweight,recyclable and environmentally friendly feature.However,the energy materials tend to distribute unevenly or fall off from CNF easily,resulting in the decrease of the devices’overall performance.Here,for the first time,we used quaternized chitosan(QCS)as stabilizer and adhesive to in situ synthesize and deposite copper sulfide nanocrystals(CuS-NCs)on CNF and further obtained the conductive paper for flexible supercapacitors.In the presence of QCS,CuS-NCs deposited in situ on CNF can be capped and stabilized by the QCS molecular chains for uniform distribution,which is conducive to the capacitive behavior and electrochemical stability of composite paper.The result shows that the specific capacitance of the composite paper was as high as 314.3 F/g at a current density of 1 A/g,a high rate capacitance of 252.6 F/g was achieved even at a high current density of 10 A/g.It reveals that the composite paper exhibited better electrochemical performance than many other CuS-based electrode materials for supercapacitor.More importantly,the composite paper performed well in various folding state without changing much electrochemical performance.Therefore,this work provides a novel strategy to in situ fabricate paper-based electrode for nextgeneration flexible energy-storage system. | Xiujie Huang Bichong Luo Chuanfu Liu Linxin Zhong Dongdong Ye Xiaoying Wang | 2021 | Nano Research2021，14，7： | 0 |
| 14 | A YAP/TAZ-CD54 axis is required for CXCR2-CD44-tumor-specific neutrophils to suppress gastric cancer显示文摘As an important part of tumor microenvironment,neutrophils are poorly understood due to their spatiotemporal heterogeneity in tumorigenesis.Here we defined,at single-cell resolution,CD44-CxCR2-neutrophils as tumor-specific neutrophils(tsNeus)in both mouse and human gastric cancer(GC).We uncovered a Hippo regulon in neutrophils with unique YAP signature genes(e.g.,ICAM1,CD14,EGR1)distinct from those identified in epithelial and/or cancer cells.Importantly,knockout of YAP/TAz in neutrophils impaired their differentiation into CD54+tsNeus and reduced their antitumor activity,leading to accelerated GC progression.Moreover,the relative amounts of CD54+tsNeus were found to be negatively associated with GC progression and positively associated with patient survival.Interestingly,GC patients receiving neoadjuvant chemotherapy had increased numbers of CD54+tsNeus.Furthermore,pharmacologically enhancing YAP activity selectively activated neutrophils to suppress refractory GC,with no significant inflammation-related side effects.Thus,our work characterized tumor-specific neutrophils in GC and revealed an essential role of YAP/TAZ-CD54 axis in tsNeus,opening a new possibility to develop neutrophil-based antitumor therapeutics. | Pingping Nie Weihong Zhang Yan Meng Moubin Lin Fenghua Guo Hui Zhang Zhenzhu Tong Meng Wang Fan Chen Liwei An Yang Tang Yi Han Ruixian Yu Wenjia Wang Yuanzhi Xu Linxin Wei Zhaocai Zhou Shi Jiao | 2023 | Protein & Cell2023，14，7： | 0 |
| 15 | Study on the Deformation Characteristics of the Sheet Hydroforming with a Movable Die显示文摘An improved sheet hydroforming process with a movable die is proposed and investigated by elastoplastic FEM. The effects of varied process parameters on the deformation of the sheet blanks were investigated. The effects of the movable die on the FLD were also analyzed. Using a movable die may increase the forming limit of the blank and improve the forming performance. Moreover, the drawing ratio of the blank may be increased by changing the process conditions such as blank holder force and the counterforce of the movable die on the blank. | Linxin ZHOU Yi XU Zhongtang WANG Shihong ZHANG | 2003 | Journal of Materials Science & Technology2003，19，z1： | 0 |
| 16 | Fabrication of Optical Tunable Helical Thin Films显示文摘Circular polarization selection of light is an important property of helical micro-nanostructure.The helical thin films fabricated by glancing angle deposition can provide both circular polarization selection and wavelength tuning in this work.Their selective transmissions were depicted in calculations and experiments.The wavelength tuning mechanism was revealed as the relationship between peak wavelength and deposition parameters.Therefore,tunable circular polarization components can be designed according to the mechanism mentioned above and fabricated by glancing angle deposition techniques.Potential applications include tunable optical filters,optical pulse-shapers,biosensors etc. | Linxin Hu Peng Wang Xingyang Wan Shaoji Jiang | 2012 | Journal of Materials Science & Technology2012，28，2： | 0 |
| 17 | Enhanced Degradation of Methyl Orange with CoFe_(2)O_(4)@Zeolite Catalyst as Peroxymonosulfate Activator:Performance and Mechanism显示文摘Reagents:PMS(KHSO_(5)·0.5KHSO_(4)·0.5K_(2)SO_(4),KHSO_(5)),MO,cobalt chloride(CoCl_(2)·6H_(2)O),ferric chloride(FeCl3·6H_(2)O),sodium metasilicate nonahydrate(Na_(2)SiO_(3)·9H_(2)O),methanol(MeOH),tert-butyl alcohol(TBA),p-Benzoquinone(p-BQ),furfuryl alcohol(FFA),sodium carbonate(Na_(2)CO_(3)),sodium sulfate(Na_(2)SO_(4)),sodium chloride(NaCl)and potassium phosphate monobasic(KH_(2)PO_(4))were purchased from Aladdin Reagent Co.,Ltd(Shanghai,China).Coal gangue were collected from Huainan,China.All chemicals above are analytical grade,and deionized water was used throughout all experiments. | WANG Lei LI Jianjun NING Jun HU Tianyu WANG Hongyang ZHANG Zhanqun WU Linxin | 2023 | 无机材料学报2023，38，4： | 0 |
| 18 | Information Purification Network for Remote Sensing Image Super-Resolution显示文摘Recently,several well-performing deep convolutional neural networks were proposed for remote sensing image super-resolution(SR).However,these methods rarely consider that remote sensing images are corruptible by additional noise,blurring,and other factors.Therefore,to eliminate the interference of these factors,especially the noise,we propose a novel information purification network(IPN)for remote sensing image SR.The proposed information purification block(IPB)can process channel-wise features differently by channel separation and rescale spatial-wise features adaptively through the proposed multi-scale spatial attention mechanism.We further design an information group to explore a more powerful expressive combination of IPBs.Moreover,long and short skip connections can transmit abundant low-frequency information,making IPBs pay more attention to high-frequency information.We mix the images under various degradation models as training data in the training phase.In this way,the network can directly reconstruct various degraded images.Experiments on AID and UC Merced Land-Use datasets under multiple degradation models demonstrate that the proposed IPN performs better than state-of-the-art methods. | Zheyuan Wang Liangliang Li Linxin Xing Jiawen Wang Kaipeng Sun Hongbing Ma | 2023 | Tsinghua Science and Technology2023，28，2： | 0 |
| 19 | Thermoelectric generator based on anisotropic wood aerogel for low-grade heat energy harvesting显示文摘Thermoelectric generators(TEGs)have received increasing attention due to their potential to harvest low-grade heat energy(<100℃ )and provide power for the Internet of Things(IoT)and wearable electronic devices.Herein,a wood-based ordered framework is used to fabricate carbon nanotube/poly(3,4-ethylenedioxythiophene)(CNT/PEDOT)wood aerogel for TEG.The prepared CNT/PEDOT wood aerogel with an anisotropic structure exhibits a low thermal conductivity of 0.17 W m^(−1)K^(−1)and is advantageous to develop a sufficient temperature gradient.Meanwhile,CNT/PEDOT composites effectively decouple the relationship between the Seebeck coefficient and electrical conductivity by energy filtering effect to enhance thermoelectric(TE)output properties.The vertical TEG assembled by the CNT/PEDOT wood aerogels reveals an output power of 1.5μW and a mass-specific power of 15.48μW g^(−1)at a temperature difference of 39.4 K.Moreover,the layered structure renders high compressibility and fatigue resistance.The anisotropic structure,high mechanical performance,and rapid thermoelectric response,enabling the TEG based on CNT/PEDOT wood aerogel offer opportunities for continuous power supply to low-power electronic devices. | Xuan Zhao Zehong Chen Hao Zhuo Yijie Hu Ge Shi Bing Wang Haihong Lai Sherif Araby Wenjia Han Xinwen Peng Linxin Zhong | 2022 | Journal of Materials Science & Technology2022，，25： | 0 |
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