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| 1 | Modulation of Longevity and Tissue Homeostasis by the Drosophila PGC-1 Homolog显示文摘 | Michael Rera Sepehr Bahadorani Jaehyoung Cho Christopher L. Koehler Matthew Ulgherait Jae H. Hur William S. Ansari Thomas Lo D. Leanne Jones David W. Walker | 2011 | Cell Metabolism2011，，5： | 2 |
| 2 | Retention ofpregnancy-related weight in the early postpartum period: implications for womeng health services显示文摘 | Walker LO Sterling BS Timmerman GM | 2005 | J Obstet Gyne- col Neonatal Nurs2005，34，4： | 1 |
| 3 | Retention of pregnancy-related weight in the early postpartum pefiod:implications for women's health services (Review)显示文摘 | Walker LO Sterling BS Timmerman GM | | 0，，： | 1 |
| 4 | Gestational weight gain and perinatal outcomes of subgroups of Asian-American women,Texas,2009显示文摘 | Cheng HR Walker LO Brown A | 2015 | Womens Health Issues2015，25，3： | 1 |
| 5 | Gestational weight gain and perinatal outcomes of subgroups of Asian-American women,Texas, 2009 显示文摘 | Cheng HR Walker LO Brown A | 2015 | Womens Health Issues2015，25，3： | 1 |
| 6 | Changes in the gastrointestinal tract during enteral or parenteral feeding显示文摘 | Lo CW Walker WA | 1989 | Nutr Rev1989，47，1： | 1 |
| 7 | 强化与标准血压控制对痴呆的影响:随机临床试验显示文摘目前还没有有效的治疗方法来降低轻度认知障碍和痴呆的风险。该文旨在探讨强化血压控制对老年痴呆风险的影响。研究人员在美国和波多黎各102个地点对年龄≥50岁有高血压但无糖尿病或脑卒中史的成人进行随机临床试验。于2010年11月8日开始,于2015年8月20日提前停止,获得其主要观察指标(复合心血管事件)和全因死亡率的数据。认知观察指标随访的最后日期为2018年7月22日。 | 刘青 叶鹏 Williamson JD Pajewski NM Auchus AP Bryan RN Chelune G Cheung AK Cleveland ML Coker LH Crowe MG Cushman WC Cutler JA Davatzikos C Desiderio L Erus G Fine LJ Gaussoin SA Harris D Hsieh MK Johnson KC Kimmel PL Tamura MK Launer LJ Lerner AJ Lewis CE Martindale-Adams J Moy CS Nasrallah IM Nichols LO Oparil S Ogrocki PK Rahman M Rapp SR Reboussin DM Rocco MV Sachs BC Sink KM Still CH Supiano MA Snyder JK Wadley VG Walker J Weiner DE Whelton PK Wilson VM Woolard N Wright JT Jr Wright CB | 2019 | 中华高血压杂志2019，27，4： | 1 |
| 8 | Changes in the gastrointestinal tract during enteral or parenteral feeding显示文摘 | Lo CW Walker WA | 1989 | Nutr Rev1989，47，7： | 1 |
| 9 | Contributions of maternal identity and lifestyle to young children's adjustment 显示文摘 | Walker LO | 1997 | Res Nurs Health1997，20，2： | 1 |
| 10 | Mental health literacy and postpartum depression: a qualitative description of views of lower income women 显示文摘 | Guy S Sterling BS Walker LO | 2014 | Arch Psyehiatr Nurs2014，28，4： | 1 |
| 11 | ASTRAL compendium enhancements 显示文摘 | Chandonia J M Walker N S Lo CONTE L etal | 2002 | Nucleic Acids Res2002，30，1： | 1 |
| 12 | Retention of pregnancy-re- lated weight in the early postpartum period: implications for women's health services显示文摘 | Walker LO Sterling BS Timmerman GM | 2005 | J Obstet Gynecol Neonatal Nuts2005，，34： | 1 |
| 13 | Changes in the gastrointestinal tract duri-ng enteral or parenteral feeding显示文摘 | Lo Cw Walker WA | 1989 | Nutr Rev1989，47，7： | 1 |
| 14 | Changes in the gastreintestinal tractduring enteral or parenteral feeding显示文摘 | Lo CW Walker WA | 1989 | Nutr Rev1989，47，1： | 1 |
| 15 | Managing excessive weight gain during pregnancy and the postpartum period显示文摘 | Walker LO | 2007 | J Obstet Gynecol Neonatal Nurs2007，36，5： | 1 |
| 16 | The ASTRAL Compendium in 2004显示文摘 | Chandonia J M Hon G Walker N S Lo Conte L Koehl P Lev- itt M Brenner S E | 2004 | Nu- cleic Acids Research2004，32，1： | 1 |
| 17 | Changes in the gastrointestinal tract during enteral or parenteral feeding显示文摘 | Lo CW Walker WA | 1989 | Nutr Rev1989，47，7： | 1 |
| 18 | STING regulates BCR signaling in normal and malignant B cells显示文摘STING is an endoplasmic reticulum(ER)-resident protein critical for sensing cytoplasmic DNA and promoting the production of type Ⅰ interferons;however,the role of STING in B cell receptor(BCR)signaling remains unclear.We generated STING V154M knock-in mice and showed that B cells carrying constitutively activated STING specifically degraded membrane-bound IgM,Ig a and Igβ via SEL1L/HRD1-mediated ER-associated degradation(ERAD).B cells with activated STING were thus less capable of responding to BCR activation by phosphorylating Igα and Syk than those without activated STING.When immunized with T-independent antigens,STING V154M mice produced significantly fewer antigen-specific plasma cells and antibodies than immunized wild-type(WT)mice.We further generated B cell-specific STING^(KO) mice and showed that STING^(KO) B cells indeed responded to activation by transducing stronger BCR signals than their STING-proficient counterparts.When B cell-specific STING^(KO) mice were T-independently immunized,they produced significantly more antigen-specific plasma cells and antibodies than immunized STIN^(WT)mice.Since both human and m ouse IGHV-unmutated malignant chronic lymphocytic leukemia(CLL)cells downregulated the expression of STING,we explored whether STING downregulation could contribute to the well-established robust BCR signaling phenotype in malignant CLL cells.We generated a STING-deficient CLL mouse model and showed that STING-deficient CLL cells were indeed more responsive to BCR activation than their STING-proficient counterparts.These results revealed a novel B cell-intrinsic role of STING in negatively regulating BCR signaling in both normal and malignant B cells. | Chih-Hang Anthony Tang Avery C.Lee Shiun Chang Qin Xu Andong Shao Yun Lo Walker T.Spalek Javier A.Pinilla-lbarz Juan R.Del Valle Chih-Chi Andrew Hu | 2021 | Cellular & Molecular Immunology2021，18，4： | 0 |
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