|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Submucosal tunneling and endoscopic resection of submucosal tumors at the esophagogastric junction显示文摘AIM: To evaluate the safety and efficacy of submucosal tunneling and endoscopic resection(STER) for treating submucosal tumors(SMTs).METHODS: Between August 2012 and October 2013, 21 patients with SMTs originating from the muscularis propria(MP) layer at the esophagogastric junction were treated by STER of their tumors. Key steps of the procedure include:(1) mucosal incision: a 2-cm longitudinal mucosal incision was made 5 cm proximal to the tumor;(2) submucosal tunneling: a submucosal tunnel was created 5 cm proximal to and 1 to 2 cm distal to the tumor;(3) tumor resection: the SMT was resected under direct endoscopic viewing;(4) hemostasis: while finishing the tumor resection, careful hemostasis of the MP defect and the tunnel was performed; and(5) mucosal closure: the mucosal incision site was closed by using hemostatic clips. During the operation, equipment used included a cap-fitted endoscope, an insulatedtip knife, a hook knife, hemostatic forceps, an injection needle, a snare, an endoclip, and a high-frequency generator. Carbon dioxide(CO2) insufflation was achieved by using a CO2 insufflator.RESULTS: The median age of the patients was 46.2 years(range, 35-59 years), and the majority were male(18 male vs 3 female). Complete resection rate was 100%(21/21). Eighteen lesions were resected en bloc. Mean tumor size was 23 mm(range, 10-40 mm), and mean procedure time was 62.9 min(range, 45-90 min). Pathological diagnosis of these tumors included leiomyoma(15 out of 21) and gastrointestinal stromal tumor(6 out of 21). Full-thickness MP resection was performed in 9 of 21 patients(42.9%), with mediastinal and subcutaneous emphysema occurring in all nine. At the completion of the procedure, all patients received closure of the incision with hemoclips. One patient required percutaneous drainage. The remaining 20patients required no further endoscopic or surgical intervention. There were no incidents of massive or delayed bleeding. The median follow-up period after the procedure was 6 mo(range, 2-14 mo). During followup, no patients were found to have residual or recurrent tumor or esophageal stricture.CONCLUSION: STER is safe, effective and feasible, which provides accurate histopathologic evaluation and curative treatment for SMTs originating from the MP layer at the esophagogastric junction. | De-Jun Zhou Zhen-Bo Dai Malcolm M Wells Dan-Lei Yu Jing Zhang Lei Zhang | 2015 | World Journal of Gastroenterology2015，21，2： | 20 |
| 2 | 静脉血栓栓塞症的抗血栓治疗:美国《胸科学》杂志指南显示文摘包括深静脉血栓和肺栓塞在内的静脉血栓栓塞症是癌症患者的主要并发症,发生率为4%~20%,并且是常见的潜在致命性急症。本文介绍了美国《胸科学》杂志指南中VET的抗血栓治疗的部分内容,其以第9版《美国胸内科医师学会循证临床实践指南》中的《静脉血栓栓塞症的抗血栓治疗:抗血栓治疗和阻止血栓形成》一文为参照,基于静脉血栓栓塞症治疗的Ⅲ期试验的发表年份,对口服抗凝剂(达比加群、利伐沙班、阿哌沙班、依度沙班)进行先后阐述(但是这一排序并不是指南专家组对药剂的优劣排序),以为临床医生提供参考。 | Kearon C Akl EA Ornelas J Blaivas A Jimenez D Bounameaux H Huisman M King CS MorrisT Sood N Stevens SM Vintch JRE Wells P Woller SC Moores CL 本刊编辑部 | 2016 | 中国全科医学2016，19，9： | 10 |
| 3 | 叶酸与甲酰四氢叶酸用于减少甲氨蝶呤治疗副作用(摘要)显示文摘1 背景 甲氨蝶呤用于治疗许多风湿病,其短期疗效已被证实。但毒性使不少患者不能从中受益,其中叶酸缺乏可增加其毒性。类风湿关节炎患者常有叶酸缺乏,经甲氨蝶呤治疗后叶酸储备就进一步减少。甲氨蝶呤的胃肠道和血液学副作用都与叶酸缺乏有关,可以预见,叶酸补充疗法将有助改善低剂量甲氨蝶呤治疗的副作用。对此,已有不少试验开展,并提出不同的副作用减少率。 | Ortiz Z SheaB Suarez Almazor M Moher D Wells G Tugwell P 姚如愚 | 2001 | 循证医学2001，1，1： | 4 |
| 4 | Faecalibacterium prausnitzii and human intestinal health显示文摘 | S Miquel R Martín O Rossi LG Bermúdez-Humarán JM Chatel H Sokol M Thomas JM Wells P Langella | 2013 | Current Opinion in Microbiology2013，，： | 3 |
| 5 | A clinical overview of WT1 gene mutations 显示文摘 | Little M Wells C | 1997 | Hum Mutat1997，9，3： | 1 |
| 6 | Complications of radicalcystectomy for nonmuscle invasive disease:comparison with muscle in-vasive disease显示文摘 | Cookson M S Chang S S Wells N | 2003 | J Urol2003，169，1： | 1 |
| 7 | Importance of left atrial appendage flow as a predictor of thromboembolic events in patients with atrial fibrillation显示文摘 | Kamp O Verhorst P M J Welling R C | 1999 | Eur Heart J1999，20，13： | 1 |
| 8 | Diagnosis of pulmonary embolism 显示文摘 | Rodger M Wells PS | 2001 | Thromb Res2001，103，： | 1 |
| 9 | Excluding pulmonary embolism at the bedside without diagnostic imaging: management of patients with suspected pulmonary embolism presenting to the emergency department by using a simple clinical model and D - Dimer显示文摘 | Wells PS Anderson DR Rodger M | 2001 | Ann Intern Med2001，135，2： | 1 |
| 10 | Systematic review:the Trousseau syndrome revisited:should we screen extensively for cancer in patients with venous thromboembolism?显示文摘 | Cartier M Le Gai G Wells PS | 2008 | Ann Intern Med2008，149，： | 1 |
| 11 | Attitude control of a reentry ve- hicle with internal dynamics 显示文摘 | Wallner E M Well K H | 2003 | Journal of Guidance Control and Dynamics2003，26，6： | 1 |
| 12 | Cardiac-resynchronization ther-apy for mild-to-moderate heart failure显示文摘 | Tang A S Wells G A Talajic M | | 0，，25： | 1 |
| 13 | Derivation of a simple clinical model to categorize patients probalfility of pulmonary embolism:increasing the models utility with the SimpliRed D-Dimmer显示文摘 | Wells P S Anderson D R Rodger M | 2000 | Thromb Haemost2000，83，： | 1 |
| 14 | Derivation of a simple clinical model to categorize patientsprobability of pulmonary embolism:increasing the models utility with the simpliRED D-dimer显示文摘 | Wells PS Anderson DR Rodger M | 2000 | Thromb Haemost2000，83，3： | 1 |
| 15 | Cardiac-resynchronization therapy for mild- to- moderate heart failure 显示文摘 | Tang AS Wells GA Talajic M | 2010 | N Engl J Med2010，363，25： | 1 |
| 16 | PRC1显示文摘 | Wei Jiang Gretchen Jimenez Nicholas J Wells Thomas J Hope Geoffrey M Wahl Tony Hunter Rikiro Fukunaga | 1998 | Molecular Cell1998，，： | 1 |
| 17 | Considerations for measuring ground CO2 effluxes with chambers显示文摘 | Welles J M Demetriades-Shah T H MeDermitt D K | 2001 | Chemical Geology2001，177，： | 1 |
| 18 | Foreign language aptitude and intelligence显示文摘 | Wesche M Edwards H & Wells W | 1982 | Applied Psycholinguistics1982，，3： | 1 |
| 19 | Factors associated with pressure ulcers in adults in acute care hospitals显示文摘 | FISH ER A R WELL S G HARRISON M B | 2004 | Holist Nurs Pract2004，18，5： | 1 |
| 20 | Unusual genetic organization of a functional type I protein secretion system in Neisseria meningitides 显示文摘 | Wooldridge KG Kizil M Wells DB | 2005 | Infect Immun2005，73，9： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员