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| 1 | Phase angle obtained by bioelectrical impedance analysis independently predicts mortality in patients with cirrhosis显示文摘AIM To evaluate the prognostic value of the phase angle(PA)obtained from bioelectrical impedance analysis(BIA) for mortality prediction in patients with cirrhosis. METHODS In total, 134 male cirrhotic patients prospectively completed clinical evaluations and nutritional assessment by BIA to obtain PAs during a 36-mo follow-up period. Mortality risk was analyzed by applying the PA cutoff point recently proposed as a malnutrition marker(PA ≤ 4.9°) in Kaplan-Meier curves and multivariate Cox regression models. RESULTS The patients were divided into two groups according to the PA cutoff value(PA > 4.9°, n = 73; PA ≤ 4.9°, n = 61). Weight, height, and body mass index were similar in both groups, but patients with PAs > 4.9° were younger and had higher mid-arm muscle circumference, albumin, and handgrip-strength values and lower severe ascites and encephalopathy incidences, interleukin(IL)-6/IL-10 ratios and C-reactive protein levels than did patients with PAs ≤ 4.9°(P ≤ 0.05). Forty-eight(35.80%) patients died due to cirrhosis, with a median of 18 mo(interquartile range, 3.3-25.6 mo) follow-up until death. Thirty-one(64.60%) of these patients were from the PA ≤ 4.9° group. PA ≤ 4.9° significantly and independently affected the mortality model adjusted for Model for End-Stage Liver Disease score and age(hazard ratio = 2.05, 95%CI: 1.11-3.77, P = 0.021). In addition, Kaplan-Meier curves showed that patients with PAs ≤ 4.9° were significantly more likely to die. CONCLUSION In male patients with cirrhosis, the PA ≤ 4.9° cutoff was associated independently with mortality and identified patients with worse metabolic, nutritional, and disease progression profiles. The PA may be a useful and reliable bedside tool to evaluate prognosis in cirrhosis. | Giliane Belarmino Maria Cristina Gonzalez Raquel S Torrinhas Priscila Sala Wellington Andraus Luiz Augusto Carneiro D'Albuquerque Rosa Maria R Pereira Valéria F Caparbo Graziela R Ravacci Lucas Damiani Steven B Heymsfield Dan L Waitzberg | 2017 | World Journal of Hepatology2017，9，7： | 11 |
| 2 | Competitive advantage on a warming planet 显示文摘 | LASH J WELLINGTON F | 2007 | Harvard Business Review2007，，3： | 1 |
| 3 | Competitive advantage on a warming planet显示文摘 | Lash J Wellington F | 2007 | Harvard Business Review2007，85，3： | 1 |
| 4 | Ultraviolet radiation and coral bleaching显示文摘 | GLEASON D F WELLINGTON G M | 1993 | Nature1993，365，28： | 1 |
| 5 | Competitive advantage on a warming planet显示文摘 | Lash J Wellington F | 2007 | Harvard Business Review2007，85，3： | 1 |
| 6 | Non invasive positive pressure ventilation for treatment of respiratory failure due to severe acute exacerbations of asthma 显示文摘 | Ram F S Wellington S Rowe B | 2005 | Cochrane Database Syst Rev2005，，00： | 1 |
| 7 | Time-Resolved Laser-Induced Fluorescence study of photoinduced electron transfer at the water/1,2-Dichloroethane interface显示文摘 | DRYFE W DING Z F WELLINGTON R G | 1997 | J Phys Chem A1997，101，： | 1 |
| 8 | The minimum sum of absolute errors regression: a state of the art survey显示文摘 | Narula S C Wellington J F | 1982 | Int Statist Rev1982，50，： | 1 |
| 9 | Variation in UVB sensitivity of planula larvae of the coral Agaricia agaricites along a depth gradient显示文摘 | GLEASON D F WELLINGTON G M | 1995 | Marine Biology1995，123，4： | 1 |
| 10 | Does the age of the host plant modulate migratory activity of Plutella xylostella 显示文摘 | Wellington G Jos H Carlos F | 2004 | Entomol Sci2004，，7： | 1 |
| 11 | Ultravioletradiation and coral bleaching显示文摘 | GLEASON D F WELLINGTON G M | 1993 | Nature1993，365，： | 1 |
| 12 | Prediction,linear regression and the minimum sum of relative errors显示文摘 | Narula S C and Wellington J F | 1997 | Technometrics1997，19，： | 1 |
| 13 | HIV-1 drug resistance in antiretroviral-naive individuals in sub-Saharan Africa after rollout of antiretroviral therapy: a multicentre observational study显示文摘 | Raph L Hamers Carole L Wallis Cissy Kityo Margaret Siwale Kishor Mandaliya Francesca Conradie Mariette E Botes Maureen Wellington Akin Osibogun Kim C E Sigaloff Immaculate Nankya Rob Schuurman Ferdinand W Wit Wendy S Stevens Michèle van Vugt Tobias F Rink | 2011 | The Lancet Infectious Diseases2011，，10： | 1 |
| 14 | Competitive advantage on a warming planet显示文摘 | Lash J and Wellington F | 2007 | Harvard Business Review2007，85，3： | 1 |
| 15 | Candida albicans triggers NLRP3-mediated pyroptosis in macrophages显示文摘 | Wellington M Koselny K Sutterwala F S | 2014 | Eukaryot Cell2014，13，2： | 1 |
| 16 | Competitive Advantage on a Wanning Planet 显示文摘 | Lash J Wellington F | 2007 | Harvard Business Review2007，85，3： | 1 |
| 17 | Determination of minocycline in human plasma by high-performance liquid chromatography coupled to tandem mass spectrometry: application to bioequivalence study显示文摘 | MARCUS V F A DEMIAN R I WELLINGTON R | 2001 | J Chromatogr B2001，755，12： | 1 |
| 18 | Ultraviolet and coral bleaching显示文摘 | GLEASON D F WELLINGTON G M | 1993 | Nature1993，365，28： | 1 |
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