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| 1 | Lipid-dependent conformational dynamics underlie the functional versatility of T-cell receptor显示文摘T 房间 receptor-CD3 建筑群(TCR ) 是能基于 CD3 细胞质的领域的各种各样的生物化学的变化开始抗原特定的有免疫力的回答的一台万用的发信号机器,但是内在的结构的基础留下逃犯。这里,我们开发了生物物理的途径学习 CD3 细胞质的领域的 conformational 动力学(CD3 CD ) 。在单个分子的水平,我们发现那 CD3 CD 能与三个功能的主题的不同坦诚有多重 conformational 状态,即, ITAM, BRS 和 PRS。因为,这些符合构造被产生 CD3 CD 有异构的类脂化合物绑定性质因此有异构的动力学。实时房间的成像实验证明不同抗原刺激能稳定 CD3 在不同符合构造的 CD 。类脂化合物依赖者 conformational 动力学因此为 TCR 的万用的发信号性质提供结构的基础。 | Xingdong Guo Chengsong Yan Hua Li Wenmao Huan Xiaoshan Shi Min Huang Yingfang Wang Weiling Pan Mingjun Cai Lunyi Li Wei Wu Yibing Bai Chi Zhang Zhijun Liu Xinyan Wang Xiaohui F Zhang Chun Tang Hongda Wang Wanli Liu Bo Ouyang Catherine C Wong Yi Cao Chenqi Xu | 2017 | Cell Research2017，27，4： | 5 |
| 2 | Organisms and ecology of the soil 显示文摘 | Brady N C Weil R R | 1996 | The Nature and Properties of Soils1996，11，： | 1 |
| 3 | Dargemont CDirect association and nuclear import of the hepatitis B virus X protein with the NF-kappaB inhibitor IkappaBalpha显示文摘 | Weil R Sirma H Giannini C | 1999 | Mol Cell Biol1999，19，9： | 1 |
| 4 | The Proterozoic supercontinent Rodinia:Paleomagnetically derived reconstructions for 1100 to 800Ma显示文摘 | Weil A B Van der Voo R MaCniocail C | 1998 | Earth and Planetary Science Letters1998，154，： | 1 |
| 5 | Comparison Utility in a Growth Mode显示文摘 | Carroll C Overland J D Weil | 1997 | Journal of Economic Growth1997，，2： | 1 |
| 6 | IDF diabetes atlas:global estimates of the prevalence of diabetes for 2011 and 2030 显示文摘 | Whiting DR Guariguata L Weil C | 2011 | Diabetes Res Clin Pract2011，94，3： | 1 |
| 7 | Footprint estimation for scalar flux measurements in the atmospheric surface-layer显示文摘 | Horst T W Weil J C | | 0，，： | 1 |
| 8 | Saving and Growth with Habit Formation显示文摘 | Carroll C Overland J D Weil | 2000 | American Economic Review2000，，90： | 1 |
| 9 | Footprint estimation for scalar flux measurements in the atmospheric surface-layer 显示文摘 | Horst T W Weil J C | 1992 | Boundary-Layer Meteorology1992，59，： | 1 |
| 10 | IDF diabetes atlas : glo- bal estimates of the prevalence of diabetes for 2011 and 2030显示文摘 | Whiting DR Guariguata L Weil C | 2011 | Diabetes Res Clin Pract2011，94，3： | 1 |
| 11 | The mutual solubilization of soap and lime soap dispersing agents 显示文摘 | WEIL J K SCHOLLENBERGER C A LINFIELD W M | 1977 | Journal of the American Oil Chemists'' Society1977，54，1： | 1 |
| 12 | Buccal eapnometry for quantitating the severity of hemorrhagic shock 显示文摘 | Cammarata GA Weil MH Castillo C J | 2009 | Shock2009，31，2： | 1 |
| 13 | Smooth muscle cells in atheresclerosis originate from the local vessel wall and not circulating progenitor cells in ApoE knockout mice 显示文摘 | Bentzon JF Weile C Sondergaard CS | 2006 | Arterioscler Thromb Vasc Biol2006，26，12： | 1 |
| 14 | Effect of refeeding on IGFI, IGFII, IGF receptors, FGF2, FGF6, and myostatin mRNA expression in rainbow trout myotomal muscle 显示文摘 | Chauvigne F Gabillard J C Weil C | 2003 | Gen Comp Endocrinol2003，132，2： | 1 |
| 15 | The phosphoinositide-3 kinase survival signaling mechanism in sepsis显示文摘 | Manukyan M C Weil B R Wang Y | 2010 | Shock2010，34，5： | 1 |
| 16 | IDF diabetes Atlas: global estimates of the prevalence of diabetes for 2011 and 2030显示文摘 | Whiting DR Guariguata L Weil C | 2011 | Diabetes Res Clin Pract2011，94，3： | 1 |
| 17 | IDF diabetesatlas: global estimates of the prevalence of diabetes for 2011 and 2030 显示文摘 | WHITING D R GUARIGUATA L WEIL C | 2011 | Diabetes Res Clin Pract2011，94，3： | 1 |
| 18 | Endocrine control of spermatogenesis in teleost fish显示文摘 | Billard R Fostier A Weil C | 1982 | Can J Aquat Sci1982，39，： | 1 |
| 19 | Prograrmned cell death in animal development 显示文摘 | Jacobson M D Weil M Raft M C | 1997 | Cell1997，88，34： | 1 |
| 20 | Endocrine control of spermatogenesis in teleost fish显示文摘 | BILLARD R FOSTIER A WEIL C | 1982 | Can J Fish Aquat Sci1982，39，： | 1 |
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