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| 1 | CT image fusion in the evaluation of radiation treatment planning for non-small cell lung cancer显示文摘Objective: We studied the application of CT image fusion in the evaluation of radiation treatment planning for non-small cell lung cancer (NSCLC). Methods: Eleven patients with NSCLC, who were treated with three-dimensional con-formal radiation therapy, were studied. Each patient underwent twice sequential planning CT scan, i.e., at pre-treatment, and at mid-treatment for field reduction planning. Three treatment plans were established in each patient: treatment plan A was based on the pre-treatment planning CT scans for the first course of treatment, plan B on the mid-treatment planning CT scans for the second course of treatment, and treatment plan F on the fused images for the whole treatment. The irradiation doses received by organs at risk in the whole treatment with treatment A and B plans were estimated by the plus of the parameters in treatment plan A and B, assuming that the parameters involve the different tissues (i.e. V20=AV20+BV20), or the same tissues within an organ (i.e. Dmax=ADmax+BDmax). The assessment parameters in the treatment plan F were calculated on the basis of the DVH of the whole treatment. Then the above assessment results were compared. Results: There were marked differ-ences between the assessment results derived from the plus of assessment parameters in treatment plan A and B, and the ones derived from treatment plan F. Conclusion: When a treatment plan is altered during the course of radiation treatment, image fusion technique should be performed in the establishment of a new one. The estimation of the assessment parameters for the whole treatment with treatment plan A and B by simple plus, is inaccurate. | WeiGe Guangjin Yuan Changhu Li Yaogui Wu Yanyan Zhang Ximing Xu | 2008 | The Chinese-German Journal of Clinical Oncology2008，7，6： | 10 |
| 2 | CHOOSING STRUCTURE-DEPENDENT DRAG COEFFICIENT IN MODELING GAS-SOLID TWO-PHASE FLOW显示文摘IntroductionGas-solid two-phase flow is often encountered in chemical reactors for the process industry. For industrial users, design, scale-up, control and optimization for these reactors require a good understanding of the hydrodynamics of gas-solid two-phase flow. For researchers, exploration and prediction of the complex phenomena call for a good comprehension of the heterogeneous structure and of the dominant mechanisms of gas-solid and solid-solid interactions. | NingYang WeiWang WeiGe JinghaiLi | 2003 | China Particuology2003，1，1： | 7 |
| 3 | SIMPLE MEASUREMENT OF RESTITUTION COEFFICIENT OF IRREGULAR PARTICLES显示文摘Restitution is an important physical and mechanical property of granular materials. However, measuring its values in instantaneous collisions between particles is very difficult, especially for ore particles of irregular shapes. In this paper, restitution is measured indirectly and statistically with two cameras recording from different angles the trajectories of the ore particles rebounding from a steel plate. The momenta of the particles prior to and after the collision are calcu- lated from the trajectories to give the restitutions of these collisions. The restitution between ore particles is then derived from the restitution of a steel ball with the steel plate measured in the same way. The approach has been proved to be practical and reliable for a variety of ore particles with moderate restitutions. | TinghuaLi JiayuanZhang WeiGe | 2004 | China Particuology2004，2，6： | 6 |
| 4 | βⅢ-Tubulin过表达与ERG融合、PTEN缺失密切相关,是预测前列腺癌进展的独立因素显示文摘前列腺癌是西方国家男性最常见的恶性肿瘤之一。目前确立的预后指标包括Gleason分级、肿瘤范围、术前PSA水平以及临床分期等,但这些参数都不足以使个体化治疗决策达到最优化,为此,作者拟寻找更合适的生物学标记来全面了解前列腺癌的生物学行为。 | Tsourlakis M C Weig P Grupp K 陈佳菁 林慧 余英豪 | 2014 | 临床与实验病理学杂志2014，30，6： | 6 |
| 5 | Genetically engineered K cells provide sufficient insulin to correct hyperglycemia in a nude murine model显示文摘基因类型 1 糖尿病 mellitus 的基于治疗的处理要求能综合并且响应生理的联盟者分泌机能上地活跃的胰岛素的一个代理人贝它房间的发展在周围的葡萄糖层次的相关变化。在这研究,鼠科的 enteroendocrine 房间线 STC-1 被稳定的转染遗传上修改。二个克隆房间被选择(STC-1-2 和 STC-1-14 ) 那在从 0 ~ 157.2 亩 IU/ml/10 (6 ) cells/d 表示胰岛素的 22 克隆之中分泌了胰岛素的高水平。在在文化媒介的葡萄糖集中从 1 公里被增加到 10 公里以后,分泌胰岛素从 40.3 +/- 升起了 0.8 ~ 56.3 +/- 3.2 亩 IU/ml (STC-1-2 ) ,并且从 10.8 +/- 0.8 ~ 23.6 +/- 2.3 亩 IU/ml (STC-1-14 ) 。在 STC-1-14 房间被植入进糖尿病的裸体老鼠以后,他们的血葡萄糖层次被归结为正常。身体重量损失也被改善。我们的数据建议遗传上设计的 K 房间以一种调整葡萄糖的方式分泌活跃胰岛素,并且在 vivo,学习证明多糖症能被房间的培植颠倒,建议到快速的人的胰岛素力量的遗传上设计的 K 房间的使用提供一条调整葡萄糖的途径对待糖尿病的多糖症。 | Yiqun Zhang Liqing Yao Kuntang Shen Meidong Xu Pinghong Zhou Weige Yang Xinyuan Liu Xinyu Qin | 2008 | Acta Biochimica et Biophysica Sinica2008，40，2： | 4 |
| 6 | A 10-miRNA risk score-based prediction model for pathological complete response to neoadjuvant chemotherapy in hormone receptor-positive breast cancer显示文摘Patients with hormone receptor(HR)-positive tumors breast cancer usually experience a relatively low pathological complete response(p CR)to neoadjuvant chemotherapy(NAC).Here,we derived a 10-micro RNA risk score(10-mi RNA RS)-based model with better performance in the prediction of p CR and validated its relation with the disease-free survival(DFS)in 755 HRpositive breast cancer patients(273,265,and 217 in the training,internal,and external validation sets,respectively).This model,presented as a nomogram,included four parameters:the 10-mi RNA RS found in our previous study,progesterone receptor(PR),human epidermal growth factor receptor 2(HER2)status,and volume transfer constant(K).Favorable calibration and discrimination of 10-mi RNA RS-based model with areas under the curve(AUC)of 0.865,0.811,and 0.804 were shown in the training,internal,and external validation sets,respectively.Patients who have higher nomogram score(>92.2)with NAC treatment would have longer DFS(hazard ratio=0.57;95%CI:0.39–0.83;P=0.004).In summary,our data showed the 10-mi RNA RS-based model could precisely identify more patients who can attain p CR to NAC,which may help clinicians formulate the personalized initial treatment strategy and consequently achieves better clinical prognosis for patients with HRpositive breast cancer. | Chang Gong Ziliang Cheng Yaping Yang Jun Shen Yingying Zhu Li Ling Wanyi Lin Zhigang Yu Zhihua Li Weige Tan Chushan Zheng Wenbo Zheng Jiajie Zhong Xiang Zhang Yunjie Zeng Qiang Liu RStephanie Huang Andrzej LKomorowski Eddy SYang François Bertucci Francesco Ricci Armando Orlandi Gianluca Franceschini Kazuaki Takabe Suzanne Klimberg Naohiro Ishii Angela Toss Mona PTan Mathew A Cherian Erwei Song | 2022 | Science China(Life Sciences)2022，65，11： | 3 |
| 7 | Mid-cycle serum levels of endogenous LH are not associated with the likelihood of pregnancy in artificial frozen-thawed embryo transfer cycles without pituitary suppression 显示文摘 | Griesinger G Weig M Schroer A | 2007 | Hum Reprod2007，22，： | 1 |
| 8 | The cutting of MWNTs using gamma radiation in the pres- ence of dilute sulfuric acid显示文摘 | PENGJ QUXX WEIGS etal | 2004 | Carbon2004，42，1213： | 1 |
| 9 | Arthrofibrosis following ACL reconstruction-reasons and outcome显示文摘 | Mayr HO Weig TG Plitz W | 2004 | Arch Orthop Trauma Surg2004，124，8： | 1 |
| 10 | Mid-cycle serum levels of endogenous LH are not associated with the likelihood of pregnancy in artificial frozen-thawed embryo transfer cycles without pituitary suppression显示文摘 | Griesinger G Weig M Schroer A | 2007 | Hum Reprod2007，22，10： | 1 |
| 11 | Decreased vascular repair and neovascular- ization with ageing: mechanisms and clinical relevance with an emphasis on hypoxia-inducible factor 1 显示文摘 | Michel R Hoenig Cesario Bianchi Anthony Rosenz weig | 2008 | Current Molecular Medicine2008，8，： | 1 |
| 12 | Enantioselective synthesis of loracarbef from sodium erythorbate 显示文摘 | Jeffery W Frazier Mike A Staszak Leland O Weige | 1992 | Tetrahedron Lett1992，33，7： | 1 |
| 13 | Enhanced cardiac contractility after gene transfer of V2 vasopressin receptors in vivo by ultrasound-guided injection or transcoronary delivery 显示文摘 | Weig H Laugwitz K L Moretti A | 2000 | Circulation2000，101，13： | 1 |
| 14 | The major intrinsic protein family of Arabidopsis has 23 members that form three distinct groups with functional aquaporins in each group显示文摘 | Weig A Deswarte C Chrispeels M J | 1997 | Plant Physiol1997，114，4： | 1 |
| 15 | Mid-cycle serum levels of endogenous LH are not associated with the likelihood of pregnancy in artificial frozen-thawed em- bryo transfer cycles without pituitary suppression显示文摘 | GRIESINGER G WEIG M SCHROER A | 2007 | Hum Reprod2007，22，10： | 1 |
| 16 | Mass spectrometric identification of covalently bound cell wall pro-teins from the fission yeast Schizosaccharomyces pombe 显示文摘 | de Groot P W J D Yin Q Y Weig M | 2007 | Yeast2007，24，4： | 1 |
| 17 | Improved clinical laboratory identification of human pathogenic yeasts by matrix-as- sisted laser desorption ionization time-of-flight mass spectrometry 显示文摘 | Bader O Weig M Taveme-Ghadwal L | 2011 | Clin Mierobiol Infect2011，17，9： | 1 |
| 18 | Eficiency of hand and rota-ry instumments in shaping oval root canals 显示文摘 | Weige EI Ayouti A Lost C | 2002 | J Endod2002，28，8： | 1 |
| 19 | Regulation of plateletglycoprotein Ⅵ (GPⅥ) surface expression and of soluble GPⅥ in patients with atrialfibrillation (AF) and acute coronary syndrome (ACS)显示文摘 | Bigalke B Stellos K Weig HJ | 2009 | Basic Res Cardiol2009，104，3： | 1 |
| 20 | The complete set of genes encoding major intrinsic proteins in Arabidopsis provides a framework for a new nomenclature for major intrinsic proteins in plants显示文摘 | JOHANSON U KARLSSON M JOHANSSON I GUSTAVSSON S SJOVALL S FRAYSSE L WEIG A R KJELLBOM P | 2001 | Plant Physiology2001，126，： | 1 |
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