|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Multiphase computed tomography radiomics of pancreatic intraductal papillary mucinous neoplasms to predict malignancy显示文摘BACKGROUND Intraductal papillary mucinous neoplasms(IPMNs)are non-invasive pancreatic precursor lesions that can potentially develop into invasive pancreatic ductal adenocarcinoma.Currently,the International Consensus Guidelines(ICG)for IPMNs provides the basis for evaluating suspected IPMNs on computed tomography(CT)imaging.Despite using the ICG,it remains challenging to accurately predict whether IPMNs harbor high grade or invasive disease which would warrant surgical resection.A supplementary quantitative radiological tool,radiomics,may improve diagnostic accuracy of radiological evaluation of IPMNs.We hypothesized that using CT whole lesion radiomics features in conjunction with the ICG could improve the diagnostic accuracy of predicting IPMN histology.AIM To evaluate whole lesion CT radiomic analysis of IPMNs for predicting malignant histology compared to International Consensus Guidelines.METHODS Fifty-one subjects who had pancreatic surgical resection at our institution with histology demonstrating IPMN and available preoperative CT imaging were included in this retrospective cohort.Whole lesion semi-automated segmentation was performed on each preoperative CT using Healthmyne software(Healthmyne,Madison,WI).Thirty-nine relevant radiomic features were extracted from each lesion on each available contrast phase.Univariate analysis of the 39 radiomics features was performed for each contrast phase and values were compared between malignant and benign IPMN groups using logistic regression.Conventional quantitative and qualitative CT measurements were also compared between groups,viaχ2(categorical)and Mann Whitney U(continuous)variables.RESULTS Twenty-nine subjects(15 males,age 71±9 years)with high grade or invasive tumor histology comprised the'malignant'cohort,while 22 subjects(11 males,age 70±7 years)with low grade tumor histology were included in the'benign'cohort.Radiomic analysis showed 18/39 precontrast,19/39 arterial phase,and 21/39 venous phase features differentiated malignant from benign IPMNs(P<0.05).Multivariate analysis including only ICG criteria yielded two significant variables:thickened and enhancing cyst wall and enhancing mural nodule<5 mm with an AUC(95%CI)of 0.817(0.709-0.926).Multivariable post contrast radiomics achieved an AUC(95%CI)of 0.87(0.767-0.974)for a model including arterial phase radiomics features and 0.834(0.716-0.953)for a model including venous phase radiomics features.Combined multivariable model including conventional variables and arterial phase radiomics features achieved an AUC(95%CI)of 0.93(0.85-1.0)with a 5-fold cross validation AUC of 0.90.CONCLUSION Multi-phase CT radiomics evaluation could play a role in improving predictive capability in diagnosing malignancy in IPMNs.Future larger studies may help determine the clinical significance of our findings. | Stuart L Polk Jung W Choi Melissa J McGettigan Trevor Rose Abraham Ahmed Jongphil Kim Kun Jiang Yoganand Balagurunathan Jin Qi Paola T Farah Alisha Rathi Jennifer B Permuth Daniel Jeong | 2020 | World Journal of Gastroenterology2020，26，24： | 5 |
| 2 | ACC/AHA 2005 Guideline Update for the Diagnosis and Management of Chronic Heart Failure in the Adult:a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines(Writing Committee to Update the 2001 Guidelines for the Evaluation and Management of Heart Failure):developed in collaboration with the American College of Chest Physicians and the International Society for Heart and Lung Transplantation:endorsed by the Heart Rhythm Society显示文摘 | Hunt S A Abraham W T Chin M H | 2005 | Circulation2005，112，12： | 1 |
| 3 | Asphalt flow improvers as intelligent fillers' for hot asphalts-a new chapter in asphalt technology显示文摘 | DAMM K W ABRAHAM J BUTZ T | 2002 | Journal of Applied Asphalt Binder Technology2002，，4： | 1 |
| 4 | The safety and tolerability of darbepoetin alfa in patients with anaemia and symptomatic heart failure 显示文摘 | KLAPHOLZ M ABRAHAM W T GHALI J K | 2009 | Eur J Heart Fail2009，11，11： | 1 |
| 5 | Cardiac re- synchronization therapy in asymptomatic or mildly symp- tomatic heart failure patients in relation to etiology: re- sults from the REVERSE (REsynchronization reVErses Remodeling in Systolic Left vEntricular Dysfunction ) study显示文摘 | Linde C Abraham W T Gold M R | 2010 | J Am Coll Cardiol2010，56，22： | 1 |
| 6 | Effects of low-dose oral enoximone administration on mortality, morbidity, and exercise capacity in patients with advanced heart failure: the randomized, double-blind, placebo-controlled, parallel group ESSENTIAL trials显示文摘 | METRA M EICHHORN E ABRAHAM W T | 2009 | Eur Heart J2009，30，24： | 1 |
| 7 | Randomized trial of car-diac resynchronization in mildly symptomatic heart failure patients andin asymptomatic patients with left ventricular dysfunction and previousheart failure symptoms显示文摘 | Linde C Abraham W T Gold M R | 2008 | J Am Coll Cardiol2008，52，23： | 1 |
| 8 | 2009 focused update incorporated into the ACC/AHA 2005 guidelines for the diagnosis an dmanagement of heart failure in adults:a report of the American college of cardiology foundation/American heart association task force on practice guidelines显示文摘 | Hunt S A Abraham W T Chin M H | | 0，，： | 1 |
| 9 | ACC/AHA2005 guide1ine update for the diagnosis and management of chronic heart failure in the adult-summary article显示文摘 | Hunt S A Abraham W T Chin M H | 2005 | Circulation2005，112，12： | 1 |
| 10 | Noninvasive homody- namic monitoring in heart failure:utilization of imped- ance cardiography显示文摘 | YANCY C ABRAHAM W T | 2003 | Congest Heart Fail2003，9，： | 1 |
| 11 | Characterization of polyploid wheat genomic diversity using a high-density 90 000 single nucleotide polymorphism array 显示文摘 | Wang SC Debbie W Kerrie F Alexandra A Shiaoman C Bevan EH Marco M Silvio S Sara GM Luigi C Anna MM Alex W Stuart S Gary B Ralf W Joerg P International Wheat Genome Sequencing Consortium Morten L Diane M Rudi A Rudy D Gina BG Abraham K Alina RA Catherine F Jerome S Michele M Curtis P Luo MC Jan DMM Jorge D Martin G Roberto T Cindy L Ivan M Colin C Keith JE Matthew H Eduard A | 2014 | Plant Biotechnol J2014，12，： | 1 |
| 12 | Character- istics of heart failure patients associated with good and poor re-sponse to cardiac resynchronization therapy: a PROSPECT (predictors of response to CRT) sub-analysis 显示文摘 | Van Bommel R J Bax J J Abraham W T | 2009 | Eur Heart2009，30，20： | 1 |
| 13 | 2009focused update:ACCF/AHA Guidelines for the Diagnosis and Management of Heart Failure in Adults:a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines:developed in collaboration with the International Society for Heart and Lung Transplantation显示文摘 | JESSUP M ABRAHAM W T CASEY D E | 2009 | Circulation2009，119，14： | 1 |
| 14 | ACC / AHA2005 guideline update for the diagnosis and management of chronic heart failure in the adult 显示文摘 | HUNT S A ABRAHAM W T CHINA M H | 2005 | J Am Coil Cardiol2005，46，6： | 1 |
| 15 | Predictors of mortality after discharge in patients hospitalized with heart failure: an analysis from the Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure (OPTIMIZE-HF) 显示文摘 | O'CONNOR C M ABRAHAM W T ALBERT N M | 2008 | Am Heart J2008，156，4： | 1 |
| 16 | ACC/AHA 2005 guideline update for the diagnosis and management of chronic heart failure in the adult~ A report of the American col- lege of cardiology 显示文摘 | Hunt S A Abraham W T Chin M H | 2005 | Circulation2005，112，12： | 1 |
| 17 | ACC/AHA 2005 Guideline update for the diagnosis and management of chronic heart failure in the adult 显示文摘 | HUNT S A ABRAHAM W T CHIN M H | 2005 | Circulation2005，112，： | 1 |
| 18 | Rationale and design of a randomized clinical trial to assess the safety and efficacy of cardiac resynchroniza- tion therapy in patients with advanced heart failure: the Multi center InSync Randomized Clinical Evaluation (MIRACLE)显示文摘 | Abraham W T | 2000 | Card FaiI2000，6，4： | 1 |
| 19 | Cardiac resynehronization in chronic heart failure显示文摘 | Abraham W T Fizher W G Smith A L | 2002 | N Engl J Med2002，346，24： | 1 |
| 20 | Consensus recommendations for the management of chronic heart failure显示文摘 | Milton Packer J N Cohn W T Abraham | 1999 | Am J Cardiol1999，83，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员