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| 1 | Balanced propofol sedation administered by nonanesthesiologists:The first Italian experience显示文摘AIM:To assess the efficacy and safety of a balanced approach using midazolam in combination with propofol,administered by nonanesthesiologists,in a large series of diagnostic colonoscopies.METHODS:Consecutive patients undergoing diagnostic colonoscopy were sedated with a single dose of midazolam(0.05 mg/kg)and lowdose propofol(starter bolus of 0.5 mg/kg and repeated boluses of 10 to 20 mg).Induction time and deepest level of sedation,adverse and serious adverse events,as well as recovery times,were prospectively assessed.Cecal intubation and adenoma detection rates were also collected.RESULTS:Overall,1593 eligible patients were included.The median dose of propofol administered was 70 mg(range:40120 mg),and the median dose of midazolam was 2.3 mg(range:24 mg).Median induction time of sedation was 3 min(range:14 min),and median recovery time was 23 min(range:1040 min).A moderate level of sedation was achieved in 1561(98%) patients,whilst a deep sedation occurred in 32(2%) cases.Transient oxygen desaturation requiring further oxygen supplementation occurred in 8(0.46%;95% CI:0.2%0.8%)patients.No serious adverse event was observed.Cecal intubation and adenoma detection rates were 93.5%and 23.4%(27.8%for male and 18.5%for female,subjects),respectively.CONCLUSION:A balanced sedation protocol provided a minimalization of the dose of propofol needed to target a moderate sedation for colonoscopy,resulting in a high safety profile for nonanesthesiologist propofol sedation. | Alessandro Repici Nico Pagano Cesare Hassan Alessandra Carlino Giacomo Rando Giuseppe Strangio Fabio Romeo Angelo Zullo Elisa Ferrara Eva Vitetta Daniel de Paula Pessoa Ferreira Silvio Danese Massimo Arosio Alberto Malesci | 2011 | World Journal of Gastroenterology2011，17，33： | 2 |
| 2 | Safety of cold polypectomy for < 10 mm polyps at colonoscopy: a prospective multicenter study显示文摘 | A. Repici C. Hassan E. Vitetta E. Ferrara G. Manes G. Gullotti A. Princiotta P. Dulbecco N. Gaffuri E. Bettoni N. Pagano G. Rando G. Strangio A. Carlino F. Romeo D. de Paula Pessoa Ferreira A. Zullo L. Ridola A. Malesci | 2012 | Endoscopy2012，，01： | 2 |
| 3 | Endoscopic submucosal dissection of early gastric neoplastic lesions: a western series显示文摘 | Alessandro Repici Angelo Zullo Cesare Hassan Paola Spaggiari Giuseppe Strangio Eva Vitetta Elisa Ferrara Alberto Malesci | 2013 | European Journal of Gastroenterology & Hepatology2013，，11： | 2 |
| 4 | A retrospective analysis of early and late outcome of biodegradable stent placement in the management of refractory anastomotic colorectal strictures显示文摘 | A. Repici N. Pagano G. Rando A. Carlino E. Vitetta E. Ferrara G. Strangio A. Zullo C. Hassan | 2013 | Surgical Endoscopy2013，，7： | 2 |
| 5 | Single-carrier frequency domain equalization显示文摘 | Pancaldi F Vitetta G | 2008 | IEEE Signal Processing Magazine2008，25，5： | 1 |
| 6 | RiVax,a recombinant ri-cin subunit vaccine,protects mice against ricin delivered by gavage or aerosol显示文摘 | Smallshaw JE Richardson JA Vitetta ES | | 0，，42： | 1 |
| 7 | Healthy aging: regulation of the metabolome by cellular redox modulation and prooxidant signaling systems: the essential roles of superoxide anion and hydrogen peroxide 显示文摘 | Linnane A W Kios M Vitetta L | 2007 | Biogerontology2007，8，5： | 1 |
| 8 | Block channel equalization in the frequency domain显示文摘 | Pancaldi F Vitetta G M | 2005 | IEEE Transactions on Communication2005，53，3： | 1 |
| 9 | Vascular leak syndrome: a side effect of immunotherapy显示文摘 | Baluna R Vitetta ES | 1997 | Immunopharmacology1997，37，23： | 1 |
| 10 | Ricin vaccine development显示文摘 | Smallshaw JE Vitetta ES | | 0，，： | 1 |
| 11 | Treatment of refractory Hodgkin's lymphoma patientswith an anti2CD25 riein A2chain immu2notoxin 显示文摘 | Schnell R Vitetta E Schindler J | 2000 | Leukemia2000，14，13： | 1 |
| 12 | Homodimers but not monomers of Rituxan (chimeric anti-CD20) induce apoptosis in human B-lymphoma cells and synergize with a chemotherapeutic agent and an immunotoxin显示文摘 | Ghetie MA Bright H Vitetta ES | 2001 | Blood2001，97，5： | 1 |
| 13 | Engineering therapeutic monocloual antibodies 显示文摘 | Liu XY Pop LM Vitetta ES | 2008 | Immunol Rev2008，222，： | 1 |
| 14 | Single and multiple cholesterol gallstones and the influence of bacteria显示文摘 | L. Vitetta S.P. Best A. Sali | 2000 | Medical Hypotheses2000，，6： | 1 |
| 15 | Migraine with and without aura:electrophysiological and functional neuroimaging evidence显示文摘 | Bramanti P Grugno R Vitetta A | 2005 | Funct Neurol2005，20，1： | 1 |
| 16 | Migraine with and without aura: eleclrophysiological and functional neuroimaging evidence显示文摘 | Bramanti P Grugno R Vitetta A | 2005 | Funct Neurol2005，20，1： | 1 |
| 17 | Restles legs syndrome in diabetic neuropathy a frequest manifestation of small fibber neu- ropathy显示文摘 | Gemignani F Brindari F Vitetta F | 2007 | J Pe@her Nerv Syst2007，112，1： | 1 |
| 18 | Single-carrier frequency domain equalization显示文摘 | Frbrizio Pancaldi Giorgio M Vitetta Reza Kalbasi | 2008 | IEEE Signal Processing Magazine2008，25，5： | 1 |
| 19 | Further resuits in carriefrequency estimation for transmissions over flat fading channels 显示文摘 | MORELLI M MENGALI U VITETTA G M | 1998 | IEEE Commun Lett1998，2，12： | 1 |
| 20 | A comparison of the in vitro and in vivo activities of IgG and Fab′ 2 fragments of a mixture of three monoclonal anti-Her-2 antibodies显示文摘 | Spiridon CI Guinn S Vitetta ES | 2004 | Clin Cancer Res2004，10，10： | 1 |
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