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| 1 | A single administration of fish oil inhibits the acute inflammatory response in rats显示文摘Objective: To investigate the antiinflammatory effects of a single administration of fish oil(FO) on the acute inflammatory response. Methods: The paw edema and pleurisy models were used to evaluate the effects of FO dissolved in olive oil(FOP) orally administered in a single dose in rats. Nitric oxide(NO) concentrations in the pleural exudate were performed according to the Griess method and the cytokine concentrations were determined by Luminex bead-based multiplex assay. Results: FOP treatment(30 and 300 mg/kg) significantly reduced paw edema. FOP treatment at 18.75, 37.5, 75.0, 150.0, and 300 mg/kg decreased both the volume of pleural exudate and cellular migration into the pleural cavity and each of these doses presented the same effectiveness. Treatment with FOP(300 mg/kg) reduced NO, TNF-α, IL-1β, and IL-6 concentrations in the pleural exudate. Conclusions: The present data provide evidence that FO has inhibitory effects on the acute inflammatory response when administered in a single dose in rats. This effect might be attributable to a direct inhibitory effect of FO on the production or release of inflammatory mediators that are involved in the pathological processes evaluated herein. | Laura Licia Milani de Arruda Franciele Queiroz Ames Damila Rodrigues de Morais Renata Grespan Ana Paula Maziero Gil Maria Angelica Raffaini Covas Pereira Silva Jesui Vergilio Visentainer Roberto Kenji Nakamura Cuman Ciomar Aparecida Bersani-Amado | 2017 | Asian Pacific Journal of Tropical Medicine2017，10，8： | 2 |
| 2 | Protective Effect of HLA‐DRB1*11 and Predisposition of HLA‐C*04 in the Development of Severe Liver Damage in Brazilian Patients with Chronic Hepatitis C Virus Infection显示文摘 | A. V. Marangon G. F. Silva C. F. V. de Moraes R. M. T. Grotto M. I. M. C. Pardini D. S. de Pauli J. E. L. Visentainer A. M. Sell R. A. Moliterno | 2012 | Scandinavian Journal of Immunology2012，，4： | 1 |
| 3 | Relationship between cytokine gene polymorphisms and graft-versushost disease after allogeneic stem cell transplantation in a Brazilian population显示文摘 | Laguila Visentainer JE Lieber SR Lopes Persoli LB | 2005 | Cytokine2005，32，34： | 1 |
| 4 | Glyphosate affects seed composition in glyphos- ate-resistant soybean显示文摘 | Zobiole L H Oliveira R S Visentainer J V | 2010 | Journalof Agricultural and Food Chemistry2010，58，7： | 1 |
| 5 | Glyphosate affects seed composition in glyphosate-resistant soybean显示文摘 | Zobiole L H S Oliveira Jr R S Visentainer J V | 2010 | J Agric Food Chem2010，58，7： | 1 |
| 6 | Lipid content and fatty acid composition of 15 marine fish species from the south coast of Brazil 显示文摘 | Visentainer J V Noffs M D Carvalho P O | 2007 | Journal of American Oil Chemist''s Society2007，84，： | 1 |
| 7 | Genetics factors associated with myelodysplastic syndromes显示文摘 | Luciana Conci Macedo Ana Paula Avenia Silvestre Camila Rodrigues Josiane Bazzo de Alencar Joana Maira Valentini Zacarias Eliane Papa Ambrosio-Albuquerque Ana Maria Sell Jeane Eliete Laguila Visentainer | 2015 | Blood Cells, Molecules and Diseases2015，，： | 1 |
| 8 | Rh, Kell,duffy,Kidd and diego blood group system polymorphismin Brazilian Japanese descendants 显示文摘 | Flores MA Visentainer JE Guelsin GA | 2014 | Transfus ApherSci2014，50，1： | 1 |
| 9 | The influence of feed supply time on the fatty acid profile of Nile tilapia (Oreochromis niloticus) fed on a diet enriched with n-3 fatty acids 显示文摘 | Justi K C Hayashi C Visentainer J V | 2003 | Food Chemistry2003，80，4： | 1 |
| 10 | Muscle com- position and fatty acid prof'de in lambs fattened in dry lot or pas- ture显示文摘 | Rowe A Macedo F A F Visentainer J V etal | 1999 | Meat Science1999，51，： | 1 |
| 11 | 显示文摘 | SILVA V M COSTA W F VISENTAINER J V SOUZA N E OLIVEIRA C C | 2010 | J Braz Chem Soc2010，21，6： | 1 |
| 12 | Association of duffy blood group gene polymorphisms with IL8 gene in chronic periodontitis显示文摘 | Sippert E A de Oliveira E S C Visentainer J E | 2013 | PLoS One2013，8，83： | 1 |
| 13 | Association of cytokine genetic polymorphism with hepatitis B infection evolution in adult patients显示文摘 | Ribeiro CS Visentainer JE Moliterno RA | 2007 | Mem Inst Oswaldo Cruz2007，102，4： | 1 |
| 14 | muscle composition and fatty acid profde in lambs fattened in dry lot or pasture显示文摘 | Rowe A Macedo F A F Visentainer J V | 1999 | Meat Science1999，51，： | 1 |
| 15 | Trans fatty acid-forming processes in foods: a review显示文摘 | MARTIN C A MILINSK M C VISENTAINER J V | 2007 | An Acad Bras Cienc2007，79，2： | 1 |
| 16 | Compara- tive analysis of eight esterification methods in the quantitative determination of vegetable oil fatty acid methyl esters (FAME) 显示文摘 | Milinsk M C Matsushita M Visentainer J V | 2008 | Journal of the Brazilian Chemical Society2008，19，8： | 1 |
| 17 | Evaluation of solvent effect on the extraction of phenolic compounds and antioxidant capacities from the berries: application of principal component analysis显示文摘 | Joana Schuelter Boeing érica Oliveira Bariz?o Beatriz Costa e Silva Paula Fernandes Montanher Vitor de Cinque Almeida Jesuí Vergilio Visentainer | 2014 | Chemistry Central Journal2014，，1： | 1 |
| 18 | Glyphosate AffectsSeed Composition in Glyphosate-resistant Soybean 显示文摘 | Zobiole LH S Oliveira Jr R S Visentainer J V | 2010 | Journal ofAgricultural and Food Chemistry2010，58，7： | 1 |
| 19 | Comparative analysis of eight esterifiation methods in the quantitative determination of vegetable oil fatty acid methyl Esters(FAME)显示文摘 | MILINSK M C MATSUSHITA M VISENTAINER J V | 2008 | J Braz Chem Soc2008，19，8： | 1 |
| 20 | Rh, Kell, Duffy,Kidd and Diego blood group system polymorphism in Brazilian Japanese descendants 显示文摘 | Flores MA Visentainer JE Guelsin GA | 2014 | Transfus Apher Sci2014，50，1： | 1 |
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