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| 1 | Hepatocellular carcinoma in cirrhotic patients with portal hypertension:Is liver resection always contraindicated?显示文摘AIM:To analyze the outcome of hepatocellular car-cinoma(HCC)resection in cirrhosis patients,related to presence of portal hypertension(PH)and extent of hepatectomy.METHODS:A retrospective analysis of 135 patients with HCC on a background of cirrhosis was submitted to curative liver resection.RESULTS:PH was present in 44(32.5%)patients.Overall mortality and morbidity were 2.2% and 33.7%,respectively.Median survival time in patients with or without PH was 31.6 and 65.1 mo,respectively(P=0.047);in the subgroup with Child-Pugh class A cirrhosis,median survival was 65.1 mo and 60.5 mo,respectively(P=0.257).Survival for patients submitted to limited liver resection was not significantly different in presence or absence of PH.Conversely,median survival for patients after resection of 2 or more segments with or without PH was 64.4 mo and 163.9 mo,respectively(P=0.035).CONCLUSION:PH is not an absolute contraindication to liver resection in Child-Pugh class A cirrhotic patients,but resection of 2 or more segments should not be recommended in patients with PH. | Andrea Ruzzenente Alessandro Valdegamberi Tommaso Campagnaro Simone Conci Silvia Pachera Calogero Iacono Alfredo Guglielmi | 2011 | World Journal of Gastroenterology2011，17，46： | 20 |
| 2 | Hepatocellular carcinoma:Surgical perspectives beyond the barcelona clinic liver cancer recommendations显示文摘The barcelona clinic liver cancer(BCLC)staging system has been approved as guidance for hepatocellular carcinoma(HCC)treatment guidelines by the main Western clinical liver associations.According to the BCLC classification,only patients with a small single HCC nodule without signs of portal hypertension or hyperbilirubinemia should undergo liver resection.In contrast,patients with intermediate-advanced HCC should be scheduled for palliative therapies,even if the lesion is resectable.Recent studies report good short-term and long-term outcomes in patients with intermediate-advanced HCC treated by liver resection.Therefore,this classification has been criticised because it excludes many patients who could benefit from curative resection.The aim of this review was to evaluate the role of surgery beyond the BCLC recommendations.Safe liver resection can be performed in patients with portal hypertension and well-compensated liver function with a 5-year survival rate of 50%.Surgery also offers good long-term result in selected patients with multiple or large HCCs with a reported 5-year survival rate of over 50%and 40%,respectively.Although macrovascular invasion is associated with a poor prognosis,liver resection provides better long-term results than palliative therapies or best supportive care.Recently,researchers have identified several genes whose altered expression influences the prognosis of patients with HCC.These genes may be useful for classifying the biological behaviour of different tumours.A revision of the BCLC classification should be introduced to provide the best treatment strategy and to ensure the best prognosis in patients with HCC. | Alfredo Guglielmi rea Ruzzenente Simone Conci Alessro Valdegamberi Marco Vitali Francesca Bertuzzo Michela De Angelis Guido Mantovani Calogero Iacono | 2014 | World Journal of Gastroenterology2014，20，24： | 16 |
| 3 | Surgical Resection Versus Local Ablation for HCC on Cirrhosis: Results from a Propensity Case-Matched Study显示文摘 | Andrea Ruzzenente Alfredo Guglielmi Marco Sandri Tommaso Campagnaro Alessandro Valdegamberi Simone Conci Fabio Bagante Gianni Turcato Mirko D’Onofrio Calogero Iacono | 2012 | Journal of Gastrointestinal Surgery2012，，2： | 3 |
| 4 | Asymmetric Dimethyl L-Arginine (ADMA) is a critical regulator of myocardial reperfusion injury显示文摘 | Suihlinger MC Conci E Haubner BJ | 2007 | Cardiovasc Res2007，75，2： | 1 |
| 5 | Natural approach for thin-walledbeam-columns with elastic-plasticity 显示文摘 | Conci A Gattass M | 1990 | InternationalJournal for Numerical Methods in Engineering1990，29，8： | 1 |
| 6 | Functional defect of natu- ral immune system in an apparent immunoeompetent patient with pulmonary cryptococcosis显示文摘 | Marroni M Pericolini E Conci E | 2007 | J Infect2007，54，5： | 1 |
| 7 | A fractal image analysis system for fabric inspection based on a box-cotmting method显示文摘 | Conci A Proenca C B | 1998 | Computer Networks and ISDN Systems1998，30，2021： | 1 |
| 8 | A fractal image analysis system for fabric inspection based on a box-counting method显示文摘 | CONCI A PROENACA C B | 1998 | Computer Networks and ISDN Systems1998，30，2021： | 1 |
| 9 | A fractal image analysis system for fabric inspection based on a box-counting method显示文摘 | CONCI A PROENCA C B | 1998 | Computer Networks and ISDN Systems1998，30，： | 1 |
| 10 | An Approach for Enhancing Fingerprint Images Using Adaptive Gabor Filter Parameters显示文摘 | DE GONZAGA S L O VIOLA F CONCI A | 2008 | Pattern Recognition and Image Analysis2008，18，3： | 1 |
| 11 | Sequence and phylogenetic analysis of genome segments S1, S2, S3 and S6 of Ma/ de Rt Cuarto virus, a newly accepted Fijivirus species显示文摘 | Dist6fano A J Conci L R Mufiz Hidalgo M | 2003 | Virus Re- search2003，92，1： | 1 |
| 12 | The laryngeal mask in the intensive care unit显示文摘 | Arosio EM Conci F | 1996 | Anaesthesia1996，51，： | 1 |
| 13 | Contextual learning of multiple target locations in visual search显示文摘 | Conci M Müailer H.J | | 0，，07： | 1 |
| 14 | A Computer Vision Approach for Textile Inspection显示文摘 | CONCI A PROENOA C B | 2000 | Textile Research Journal2000，70，4： | 1 |
| 15 | Limitations of perceptual segmentation on contextual cueing in visual search显示文摘 | Conci M von Mühlenen A | | 0，，02： | 1 |
| 16 | A Comparison between ImageProcessing Approaches to Textile Inspection显示文摘 | CONCI A PROCENCA C B | 2000 | Journal of Textile Institute2000，91，2： | 1 |
| 17 | Contextual remapping in visual search after predictable targetlocation changes显示文摘 | Conci M Sun L Müller H.J | | 0，，04： | 1 |
| 18 | Influence of cu- ring temperature on the evolution of magnesium oxychloride cement 显示文摘 | Sglavo V M De Genua F Conci A | 2011 | J Mater Sci2011，46，20： | 1 |
| 19 | Characterizing the lacunarity of objects and image sets and its use as a technique for the analysis of textural patterns显示文摘 | de Melo RHC Vieira EA Conci A | 2006 | Advanced Concepts for Intelligent Vision Systems Lecture Notes in Computer Science2006，4179，： | 1 |
| 20 | Natural approach for thin-wall beamcolumns with elastic-plasticity 显示文摘 | CONCI A GATTASS M | 1990 | International Journal for Numerical Methods in Engineering1990，29，： | 1 |
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