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| 1 | Outcome of distal end clavicle fractures treated with locking plates显示文摘 | Raju Vaishya Vipul Vijay Vikram Khanna | 2017 | Chinese Journal of Traumatology2017，20，1： | 12 |
| 2 | Overall rate, location, and predictive factors for positive surgical margins after robot-assisted laparoscopic radical prostatectomy for high-risk prostate cancer显示文摘我们与高风险的前列腺癌症在 271 个病人报导全面的率,地点和积极外科的边缘(PSM ) 的预兆的因素。在 2008 年 4 月和 2011 年 10 月之间,我们有希望地从作为 D'Amico 分类的病人收集了数据高风险经历了帮助机器人的 laparoscopic 激进分子前列腺切除术。PSM 的全面的率和地点被报导。逐步的逻辑回归模型被适合估计 PSM 的预兆的因素。PSM 的全面的率是 25.1%(271 个病人中的 68 个) 。这些 PSM,(68 中的 26 个)38.2% 是 posterolateral (PL ) , 26.5%(68 中的 18 个) multifocal, 16.2%(68 中的 11 个) 在顶, 14.7%(68 中的 10 个) 在膀胱颈,并且 4.4%(3/68 ) 在另外的地点。有病理学的阶段 pT2 的病人的 PSM 率是 8.6%(140 中的 12 个) , 26.6%(64 中的 17 个) pT3a, 53.3%(32/60 ) pT4 的 pT3b,和 100%(7 中的 7 个) 。在包括 pre- , intra- ,和手术后的参数的一个逻辑回归模型,身体团索引(机会比率[或] :1.09;95% 信心间隔[CI ] :1.01-1.19, P= 0.029 ) ,病理学的舞台(pT3b 或更高对 pT2;或:5.14;95% CI:1.92-13.78;P = 0.001 ) 并且肿瘤的百分比(或:46.71;95% CI:6.37-342.57;P < 0.001 ) 是为 PSM 的独立预兆的因素。在病人在的 PSM 的最普通的地点高风险是 PL 方面,它反映报导肿瘤攻击性。PSM 的唯一的重要预兆的因素是病理学的结果,例如在标本和病理学的舞台的肿瘤的百分比。 | Sung Gu Kang Oscar Schatloff Abdul Muhsin Haidar Srinivas Samavedi Kenneth J Palmer Jun Cheon Vipul R Patel | 2016 | Asian Journal of Andrology2016，18，1： | 9 |
| 3 | Lessons learned from an audit of 1250 anal fistula patients operated at a single center:A retrospective review显示文摘BACKGROUND A complex anal fistula is a challenging disease to manage.AIM To review the experience and insights gained in treating a large cohort of patients at an exclusive fistula center.METHODS Anal fistulas operated on by a single surgeon over 14 years were analyzed.Preoperative magnetic resonance imaging was done in all patients.Four procedures were performed:fistulotomy;two novel sphincter-saving procedures,proximal superficial cauterization of the internal opening and regular emptying and curettage of fistula tracts(PERFACT)and transanal opening of intersphincteric space(TROPIS),and anal fistula plug.PERFACT was initiated before TROPIS.As per the institutional GFRI algorithm,fistulotomy was done in simple fistulas,and TROPIS was done in complex fistulas.Fistulas with associated abscesses were treated by definitive surgery.Incontinence was evaluated objectively by Vaizey incontinence scores.RESULTS A total of 1351 anal fistula operations were performed in 1250 patients.The overall fistula healing rate was 19.4%in anal fistula plug(n=56),50.3%in PERFACT(n=175),86%in TROPIS(n=408),and 98.6%in fistulotomy(n=611)patients.Continence did not change significantly after surgery in any group.As per the new algorithm,1019 patients were operated with either the fistulotomy or TROPIS procedure.The overall success rate was 93.5%in those patients.In a subgroup analysis,the overall healing rate in supralevator,horseshoe,and fistulas with an associated abscess was 82%,85.8%,and 90.6%,respectively.The 90.6%healing rate in fistulas with an associated abscess was comparable to that of fistulas with no abscess(94.5%,P=0.057,not significant).CONCLUSION Fistulotomy had a high 98.6%healing rate in simple fistulas without deterioration of continence if the patient selection was done judiciously.The sphincter-sparing procedure,TROPIS,was safe,with a satisfactory 86%healing rate for complex fistulas.This is the largest anal fistula series to date. | Pankaj Garg Baljit Kaur Ankita Goyal Vipul D Yagnik Sushil Dawka Geetha R Menon | 2021 | World Journal of Gastrointestinal Surgery2021，13，4： | 8 |
| 4 | Outcome of surgical treatment of type IV capitellum frac- tures in adults显示文摘 | Ajay Pal Singh Ish Kumar Dhammi Vipul Garg Arun Pal Singh | 2012 | Chinese Journal of Traumatology2012，15，4： | 7 |
| 5 | Guidelines on postoperative magnetic resonance imaging in patients operated for cryptoglandular anal fistula:Experience from 2404 scans显示文摘Magnetic resonance imaging(MRI)is considered the gold standard for the evaluation of anal fistulas.There is sufficient literature available outlining the interpretation of fistula MRI before performing surgery.However,the interpretation of MRI becomes quite challenging in the postoperative period after the surgery of fistula has been undertaken.Incidentally,there are scarce data and no set guidelines regarding analysis of fistula MRI in the postoperative period.In this article,we discuss the challenges faced while interpreting the postoperative MRI,the timing of the postoperative MRI,the utility of MRI in the postoperative period for the management of anal fistulas,the importance of the active involvement and experience of the treating clinician in interpreting MRI scans,and the latest advancements in the field. | Pankaj Garg Baljit Kaur Vipul D Yagnik Sushil Dawka Geetha R Menon | 2021 | World Journal of Gastroenterology2021，27，33： | 6 |
| 6 | Totally intracorporeal robot-assisted urinary diversion for bladder cancer(part 2).Review and detailed characterization of the existing intracorporeal orthotopic ileal neobladder显示文摘Objective:To review the most used intracorporeal orthotopic ileal neobladder(ICONB)after radical cystectomy for bladder cancer and create a unified compendium of the different alternatives,including new consistent images.Methods:We performed a non-systematic review of the literature with the keywords“bladder cancer”,“urinary diversion”,“radical cystectomy”,and“neobladder”.Results:Forty studies were included in the analysis.The most frequent type of ICONB was the modified Studer“U”neobladder(70%)followed by the Hautmann“W”modified neobladder(7.5%),the“Y”neobladder(5%),and the Padua neobladder(5%).The operative time to perform a urinary diversion ranged from 124 to 553 min.The total estimated blood loss ranged from 200 to 900 mL.The rate of positive surgical margins ranged from 0%to 8.1%.Early minor and major complication rates ranged from 0%to 100%and from 0%to 33%,respectively.Late minor and major complication rates ranged from 0%to 70%and from 0%to 25%,respectively.Conclusion:The most frequent types of ICONB are Studer“U”neobladder,Hautmann“W”neobladder,“Y”neobladder,and the Padua neobladder.Randomized studies comparing the performance of the different types of ICONB,the performance in an intra or extracorporeal manner,or the performance of an ICONB versus ICIC are lacking in the literature.To this day,there are not sufficient quality data to determine the supremacy of one technique.This manuscript represents a compendium of the most used ICONB with detailed descriptions of the technical aspects,operative and perioperative outcomes,and new consistent images of each technique. | Hugo Otaola-Arca Kulthe Ramesh Seetharam Bhat Vipul R.Patel Marcio Covas Moschovas Marcelo Orvieto | 2021 | Asian Journal of Urology2021，8，1： | 5 |
| 7 | Nerve-sparing robot-assisted radical prostatectomy:Current perspectives显示文摘Robotic-assisted radical prostatectomy(RARP)is the current standard of care with long term cure in organ-confined disease.The introduction of nerve-sparing(NS)to standard RARP has shown positive results in terms of functional outcomes in addition to the oncological outcomes.This article reviews the current perspectives of NS-RARP in terms of applied anatomy of the prostatic fascial planes,the neurovascular bundle(NVB),various NS techniques and postoperative functional outcomes.A non-systematic review was done using PubMed,Embase and Medline databases to retrieve and analyse articles in English,with following keywords“prostate cancer”,“robotic radical prostatectomy”,“nerve-sparing”.The Delphi method was used with an expert panel of robotic surgeons in urology to analyse the potency outcomes of various published comparative and non-comparative studies.The literature has shown that NS-RARP involves various techniques and approaches while there is a lack of randomized studies to suggest the superiority of one over the other.Variables such as preoperative risk assessments,baseline potency,surgical anatomy of individual patients and surgeons’expertise play a major role in the outcomes.A tailored approach for each patient is required for applying the NS approach during RARP. | Anup Kumar Vipul RPatel Sridhar Panaiyadiyan Kulthe Ramesh Seetharam Bhat Marcio Covas Moschovas Brusabhanu Nayak | 2021 | Asian Journal of Urology2021，8，1： | 4 |
| 8 | 机器人辅助腹腔镜根治前列腺切除术的外科学习曲线:一名外科医生500病例的经验显示文摘本文分析了机器人辅助腹腔镜根治前列腺切除术(RALP)初期250例和后期250例患者。500位连续接受RALP的临床局部前列腺癌患者分为第Ⅰ组:第1-250案(2006年12月-2010年12月)和第Ⅱ组:第251-500案(2011年1月-2012年12月)。记录两组的临床特点,比较两组的操作参数和手术期并发症。评估病理结果、肿瘤细胞残留手术组织边缘和生化复发率(BCR)。我们从每50个RALP案例中分析肿瘤细胞残留手术组织边缘fPSM)和神经血管束(NVB)保留,局部肿瘤的复发风险和病理分期的关系。第Ⅱ组比第1组有更多的晚期前列腺癌(切片检查格里森分数8—10,P=0.033:临床分期T3,P=0.叭7),并呈现显著性差异。控制台时间和失血从第Ⅰ组到第Ⅱ组大幅下降(控制台时间为165.16±53.51min vs 103.37±22.04min;失血为174.56±201.32ml vs 99.80±104.77m1)。输血在第1组减少3.2%(8/250)vs第Ⅱ组减少1.2%(3/250)以及手术期并发症比率在第1组减少9.6%(24/250)VS第Ⅱ组减少5.6%(14/250)。pT3的肿瘤细胞残留手术组织边缘N49%(第1组)降到32.6%(第Ⅱ组)。每50个案例减少肿瘤细胞残留手术组织边缘(PSM)的重要趋势,包括pT3和高度危险。神经血管束(NVB)保留会严重影响高度危险患者的肿瘤细胞残留手术组织边缘(PSM)(84.1%NVB保留群vs 43.9%NVB保留群)。3年、5年和7年无BCR的幸存者分别为79.2%、75.3%和70.2%。T3的肿瘤细胞残留手术组织边缘自初期250个案例的49%大幅下降到随后250个的32.9%。每50个案例减少PSM的重要趋势,包括pT3和高度危险。因为PSM的增加,在RALP期间不建议对高度危险的前列腺癌进行神经血管束保留。 | Yen-Chuan OU Chun-Kuang Yang Kuangh-Si Chang John Wang Siu-Wan Hung Min-Che Tung Ashutosh K Tewari Vipul R Patel | 2014 | Asian Journal of Andrology2014，16，5： | 3 |
| 9 | Totally intracorporeal robot-assisted urinary diversion for bladder cancer(Part 1).Review and detailed characterization of ileal conduit and modified Indiana pouch显示文摘Objective:To review the most used robot-assisted cutaneous urinary diversion(CUD)after radical cystectomy for bladder cancer and create a unified compendium of the different alternatives,including new consistent images Methods:A non-systematic review of the literature with the keywords“bladder cancer”,“cutaneous urinary diversion”,and“radical cystectomy”was performed.Results:Twenty-four studies of intracorporeal ileal conduit(ICIC)and two of intracorporeal Indiana pouch(ICIP)were included in the analysis.Regarding ICIC,the patients’age ranged from 60 to 76 years.The operative time to perform a urinary diversion ranged from 60 to 133 min.The total estimated blood loss ranged from 200 to 1117 mL.The rate of positive surgical margins ranged from 0%to 14.3%.Early minor and major complication rates ranged from 0%to 71.4%and from 0%to 53.4%,respectively.Late minor and major complication rates ranged from 0%to 66%and from 0%to 32%,respectively.Totally ICIP data are limited to one case report and one clinical series.Conclusion:The most frequent type of CUD is ICIC.Randomized studies comparing the performance of the different types of CUD,the performance in an intra-or extracorporeal manner,or the performance of a CUD versus orthotopic ileal neobladder are lacking in the literature.To this day,there are not enough quality data to determine the supremacy of one technique.This manuscript represents a compendium of the most used CUD with detailed descriptions of the technical aspects,operative and perioperative outcomes,and new consistent images for each technique. | Hugo Otaola-Arca Rafael Coelho Vipul R.Patel Marcelo Orvieto | 2021 | Asian Journal of Urology2021，8，1： | 3 |
| 10 | Additive QTLs on three chromosomes control flowering time in woodland strawberry(Fragaria vesca L.)显示文摘Flowering time is an important trait that affects survival,reproduction and yield in both wild and cultivated plants.Therefore,many studies have focused on the identification of flowering time quantitative trait locus(QTLs)in different crops,and molecular control of this trait has been extensively investigated in model species.Here we report the mapping of QTLs for flowering time and vegetative traits in a large woodland strawberry mapping population that was phenotyped both under field conditions and in a greenhouse after flower induction in the field.The greenhouse experiment revealed additive QTLs in three linkage groups(LG),two on both LG4 and LG7,and one on LG6 that explain about half of the flowering time variance in the population.Three of the QTLs were newly identified in this study,and one co-localized with the previously characterized FvTFL1 gene.An additional strong QTL corresponding to previously mapped PFRU was detected in both field and greenhouse experiments indicating that gene(s)in this locus can control the timing of flowering in different environments in addition to the duration of flowering and axillary bud differentiation to runners and branch crowns.Several putative flowering time genes were identified in these QTL regions that await functional validation.Our results indicate that a few major QTLs may control flowering time and axillary bud differentiation in strawberries.We suggest that the identification of causal genes in the diploid strawberry may enable fine tuning of flowering time and vegetative growth in the closely related octoploid cultivated strawberry. | Samia Samad Takeshi Kurokura Elli Koskela Tuomas Toivainen Vipul Patel Katriina Mouhu Daniel James Sargent Timo Hytönen | 2017 | Horticulture Research2017，4，1： | 3 |
| 11 | Diagnosis of anorectal tuberculosis by polymerase chain reaction,GeneXpert and histopathology in 1336 samples in 776 anal fistula patients显示文摘BACKGROUND The association of tuberculosis(TB)with anal fistulas can make its treatment quite difficult.The main challenge is timely detection of TB in anal fistulas and its proper management.There is little data available on diagnosis and management of TB in anal fistulas.AIM To detect TB in fistula-in-ano patients were analyzed in different methods utilized.METHODS A retrospective analysis of different methods,polymerase chain-reaction(PCR),GeneXpert and histopathology(HPE),utilized to detect tuberculosis in fistula-inano patients,treated between 2014-2020,was performed.The sampling was done for tissue(fistula tract lining)and pus(when available).The detection rate of various tests to detect TB and prevalence rate of TB in simple vs complex fistulae were studied.RESULTS In 1336 samples(776 patients)tested,TB was detected in 133 samples(122 patients).TB was detected in 52/703(7.4%)samples tested by PCR-tissue,in 77/331(23.2%)samples tested by PCR-pus,3/197(1.5%)samples tested with HPE-tissue and 1/105(0.9%)samples tested by GeneXpert.To detect TB,PCRtissue was significantly better than HPE-tissue(52/703 vs 3/197 respectively)(P=0.0012,significant,Fisher’s exact test)and PCR-pus was significantly better than PCR-tissue(77/331 vs 52/703 respectively)(P<0.00001,significant,Fisher’s exact test).TB fistulas were more complex than non-tuberculous fistulas[78/113(69%)vs 278/727(44.3%)respectively](P<0.00001,significant,Fisher’s exact test)but the overall healing rate was similar in tuberculous and non-tuberculous fistula groups[90/102(88.2%)vs 518/556(93.2%)respectively](P=0.10,not significant,Fisher’s exact test).CONCLUSION This is the largest study of anorectal TB to be published.The detection of TB by polymerase chain-reaction was significantly higher than by histopathology and GeneXpert.Amongst polymerase chain-reaction,pus had a higher detection rate than tissue.TB fistulas were more complex than non-tuberculous fistulas but aggressive diagnosis and meticulous treatment led to comparable overall success rates in both groups. | Pankaj Garg Ankita Goyal Vipul D Yagnik Sushil Dawka Geetha R Menon | 2021 | World Journal of Gastrointestinal Surgery2021，13，4： | 3 |
| 12 | Single-port technique evolution and current practice in urologic procedures显示文摘Different groups described the single-port surgery since its first report in laparoscopic procedures.However,the acceptance of this technique among urologists,even after the robotic approach,was reduced in the past years.Therefore,to overcome the challenges related to the single-port surgery,a new robotic platform named da Vinci SP was created with exclusive single port technology.We performed a non-systematic literature review regarding the single port technique in urologic surgeries since the first laparoscopic report until the da Vinci SP robotic platform.Three different periods were described(laparoscopy,robotic,and da Vinci SP),and we focused in our experience with this new single port robot.We selected different articles and summarized the information regarding the use of single-site surgery in laparoscopic procedures and the challenges of this approach.We also reported the experience of different groups using the single port robotic technique and some recent reports of the da Vinci SP approach.In our experience with this new console,we described some critical points related to our radical prostatectomy technique and the lessons learned during the introduction of this novel platform.Previous single-site procedures described some common challenges that limited the technique expansion.However,our experience with the da Vinci SP described feasible and safe procedures with acceptable intraoperative outcomes.The introduction of this platform is recent in the market,and the literature still lacks a high level of evidence describing the long-term outcomes of this new technology. | Marcio Covas Moschovas Kulthe Ramesh Seetharam Bhat Fikret Fatih Onol Travis Rogers Gabriel Ogaya-Pinies Shannon Roof Vipul R.Patel | 2021 | Asian Journal of Urology2021，8，1： | 3 |
| 13 | Magnetic resonance imaging-guided prostate biopsydA review of literature显示文摘Objective:Multiparametric magnetic resonance imaging(MP-MRI)helps to identify lesion of prostate with reasonable accuracy.We aim to describe the various uses of MP-MRI for prostate biopsy comparing different techniques of MP-MRI guided biopsy.Materials and methods:A literature search was performed for“multiparametric MRI”,“MRI fusion biopsy”,“MRI guided biopsy”,“prostate biopsy”,“MRI cognitive biopsy”,“MRI fusion biopsy systems”,“prostate biopsy”and“cost analysis”.The search operation was performed using the operator“OR”and“AND”with the above key words.All relevant systematic reviews,original articles,case series,and case reports were selected for this review.Results:The sensitivity of MRI targeted biopsy(MRI-TB)is between 91%e93%,and the specificity is between 36%e41%in various studies.It also has a high negative predictive value(NPV)of 89%e92%and a positive predictive value(PPV)of 51%e52%.The yield of MRI fusion biopsy(MRI-FB)is similar,if not superior to MR cognitive biopsy.In-bore MRI-TB had better detection rates compared to MR cognitive biopsy,but were similar to MR fusion biopsy.Conclusions:The use of MRI guidance in prostate biopsy is inevitable,subject to availability,cost,and experience.Any one of the three modalities(i.e.MRI cognitive,MRI fusion and MRI in-bore approach)can be used.MRI-FB has a fine balance with regards to accuracy,practicality and affordability. | Kulthe Ramesh Seetharam Bhat Srinivas Samavedi Marcio Covas Moschovas Fikret Fatih Onol Shannon Roof Travis Rogers Vipul R.Patel Ananthakrishnan Sivaraman | 2021 | Asian Journal of Urology2021，8，1： | 3 |
| 14 | Computerized tomography based “patient specific blocks” improve postoperative mechanical alignment in primary total knee arthroplasty显示文摘AIM: To compare the postoperative mechanical alignment achieved after total knee arthroplasty(TKA) using computer tomography(CT) based patient specific blocks(PSB) to conventional instruments(CI).METHODS: Total 80 knees were included in the study, with 40 knees in both the groups operated using PSB and CI. All the knees were performed by a single surgeon using the same cruciate sacrificing implants. In our study we used CT based PSB to compare with CI. Postoperative mechanical femoro-tibial angle(MFT angle) was measured on long leg x-rays using picture archiving and communication system(PACS). We compared mechanical alignment achieved using PSB and CI in TKA using statistical analysis.RESULTS: The PSB group(group 1) included 17 females and seven males while in CI group(group 2) there were 15 females and eight males. The mean age of patients in group 1 was 60.5 years and in group 2 it was 60.2 years. The mean postoperative MFT angle measured on long-leg radiographs in group 1 was 178.23°(SD = 2.67°, range: 171.9° to 182.5°) while in group 2, the mean MFT angle was 175.73°(SD = 3.62°, range: 166.0° to 179.8°). There was significant improvement in postoperative mechanical alignment(P value = 0.001), in PSB group compared to CI. Number of outliers were also found to be less in group operated with PSB(7 Knee) compared to those operated with CI(17 Knee).CONCLUSION: PSB improve mechanical alignment after total knee arthroplasty, compared to CI. This may lead to lower rates of revision in the PSB based TKA as compared to the conventional instrumentation. | Raju Vaishya Vipul Vijay Vikas P Birla Amit K Agarwal | 2016 | World Journal of Orthopedics2016，7，7： | 2 |
| 15 | Guidelines to diagnose and treat peri-levator high-5 anal fistulas: Supralevator, suprasphincteric, extrasphincteric, high outersphincteric, and high intrarectal fistulas显示文摘Supralevator,suprasphincteric,extrasphincteric,and high intrarectal fistulas(high fistulas in muscle layers of the rectal wall)are well-known high anal fistulas which are considered the most complex and extremely challenging fistulas to manage.Magnetic resonance imaging has brought more clarity to the pathophysiology of these fistulas.Along with these fistulas,a new type of complex fistula in high outersphincteric space,a fistula at the roof of ischiorectal fossa inside the levator ani muscle(RIFIL),has been described.The diagnosis,management,and prognosis of RIFIL fistulas is reported to be even worse than supralevator and suprasphincteric fistulas.There is a lot of confusion regarding the anatomy,diagnosis,and management of these five types of fistulas.The main reason for this is the paucity of literature about these fistulas.The common feature of all these fistulas is their complete involvement of the external anal sphincter.Therefore,fistulotomy,the simplest and most commonly performed procedure,is practically ruled out in these fistulas and a sphincter-saving procedure needs to be performed.Recent advances have provided new insights into the anatomy,radiological modalities,diagnosis,and management of these five types of high fistulas.These have been discussed and guidelines formulated for the diagnosis and treatment of these fistulas for the first time in this paper. | Pankaj Garg Vipul D Yagnik Sushil Dawka Baljit Kaur Geetha R Menon | 2022 | World Journal of Gastroenterology2022，28，16： | 2 |
| 16 | A new bead‐based human platelet antigen antibodies detection assay versus the monoclonal antibody immobilization of platelet antigens assay显示文摘 | Leendert Porcelijn Elly Huiskes Ilona Comijs‐van Osselen Aniska Chhatta Vipul Rathore Matthew Meyers Masja Haas | 2014 | Transfusion2014，，6： | 2 |
| 17 | LC and LC–MS/MS studies for the identification and characterization of degradation products of acebutolol显示文摘The aim of the present investigation was to demonstrate an approach involving use of liquid chromatography(LC) and liquid chromatography-mass spectrometry(LC–MS) to separate, identify and characterize very small quantities of degradation products(DPs) of acebutolol without their isolation from the reaction mixtures. The drug was subjected to oxidative, hydrolytic, thermal and photolytic stress conditions as per International Conference on Harmonization(ICH) guideline Q1 A(R2). Among all the stress conditions the drug was found to be labile in hydrolytic(acidic & basic) and photolytic stress conditions, while it was stable in water-induced hydrolysis, oxidative and thermal stress conditions. A total of four degradation products were formed. A C18 column was employed for the separation of all the DPs on a gradient mode by using high-performance liquid chromatography(HPLC). All the DPs were characterized with the help of their fragmentation pattern and the masses obtained upon LC–MS/MS and MSnanalysis. All the hitherto unknown degradation products were identified as 1-(2-(2-hydroxy-3-(isopropylamino)propoxy)-5-(amino)phenyl)ethanone(DP-I), N-(4-(2-hydroxy-3-(isopropylamino)propoxy)-3-acetylphenyl)acrylamide(DP-II), 1-(2-(2-hydroxy-3-(isopropylamino)propoxy)-5-(hydroxymethylamino)phenyl)ethanone(DP-III) and 1-(6-(2-hydroxy-3-(isopropylamino)propoxy)-2,3-dihydro-2-propylbenzo[d]oxazol-5-yl)ethanone(DP-IV). Finally the in-silico carcinogenicity and hepatotoxicity predictions of the drug and all the DPs were performed by using toxicity prediction softwares viz., TOPKAT, LAZAR and Discovery Studio ADMET. The results of in-silico toxicity studies revealed that acebutolol(0.967) and DP-I(0.986) were found to be carcinogenic, while acebutolol(0.490) and DP-IV(0.437) were found to be hepatotoxic. | Uday Rakibe Ravi Tiwari Anand Mahajan Vipul Rane Pravin Wakte | 2018 | Journal of Pharmaceutical Analysis2018，8，6： | 2 |
| 18 | Dislocation of a constrained total knee arthroplasty with patellar tendon rupture after trivial trauma显示文摘 | Raju Vaishya Vipul Vijay Abhishek Vaish | 2015 | Chinese Journal of Traumatology2015，18，4： | 2 |
| 19 | Robotic surgery techniques to approach benign prostatic hyperplasia disease:A comprehensive literature review and the state of art显示文摘Objective:The robotic-assisted approach to simple prostatectomy(RASP)was conceived,essentially reproducing the fundaments of open simple prostatectomy.Since the first report,RASP underwent several technical modifications.The study aims to identify and describe the current robotic surgery techniques to approach benign prostatic hyperplasia(BPH).Methods:The paper performed a non-systematic literature review accessing PubMed and Embase databases for all full-text articles published from 2008 to May 2020,assessing robot-assisted surgical techniques for BPH treatment using the terms“robot-assisted simple prostatectomy”OR“robotic simple prostatectomy”OR“RASP”AND“surgical technique”.Results:After careful review of 180 studies in PubMed and 198 in Embase,16 papers reporting different RASP techniques.After the first procedure described by Sotelo et al.[9],several authors contributed to the development of the RASP technique.John et al.[24]proposed the extraperitoneal access,and Yuh et al.[23]first reported the adenoma transcapsular dissection.Some modifications were proposed by Coelho et al.[31]on trigonization,posterior reconstruction,and urethro-vesical anastomosis.Other groups focused on urethral-preserving procedures.Moschovas et al.[28]and Clavijo et al.[32]recently described an intrafascial RASP with the removal of the entire prostatic tissue.Finally,Kaouk et al.[29]reported the feasibility and safety of the da Vinci Single Port approach.Conclusion:In the last eighteen years,the robotic-assisted approach to BPH disease has been evolved,and different techniques have been described.This review details all the technical developments on RASP that distinctive groups have proposed since the multiport robotic platforms until the new da Vinci Single Port. | Marcio Covas Moschovas Frederico Timo´teo Leonardo Lins Ose´as de Castro Neves Kulthe Ramesh Seetharam Bhat Vipul R.Patel | 2021 | Asian Journal of Urology2021，8，1： | 2 |
| 20 | OBSERVER: An Approach for Query Processing in Global Information Systems Based on Interoperation Across Pre-Existing Ontologies显示文摘 | Eduardo Mena Arantza Illarramendi Vipul Kashyap Amit P. Sheth | 2000 | Distributed and Parallel Databases2000，，2： | 1 |
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