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| 1 | Pediatric nonalcoholic fatty liver disease,metabolic syndrome and cardiovascular risk显示文摘Nonalcoholic fatty liver disease(NAFLD) encompasses a range of liver histology severity and outcomes in the absence of chronic alcohol use.The mildest form is simple steatosis in which triglycerides accumulate within hepatocytes.A more advanced form of NAFLD,nonalcoholic steatohepatitis,includes inflammation and liver cell injury,progressive to cryptogenic cirrhosis.NAFLD has become the most common cause of chronic liver disease in children and adolescents.The recent rise in the prevalence rates of overweight and obesity likely explains the NAFLD epidemic worldwide.NAFLD is strongly associated with abdominal obesity,type 2 diabetes,and dyslipidemia,and most patients have evidence of insulin resistance.Thus,NAFLD shares many features of the metabolic syndrome(MetS),a highly atherogenic condition,and this has stimulated interest in the possible role of NAFLD in the development of atherosclerosis.Accumulating evidence suggests thatNAFLD is associated with a significantly greater overall mortality than in the general population,as well as with increased prevalence of cardiovascular disease(CVD),independently of classical atherosclerotic risk factors.Yet,several studies including the pediatric population have reported independent associations between NAFLD and impaired flow-mediated vasodilatation and increased carotid artery intimal medial thickness-two reliable markers of subclinical atherosclerosis-after adjusting for cardiovascular risk factors and MetS.Therefore,the rising prevalence of obesity-related MetS and NAFLD in childhood may lead to a parallel increase in adverse cardiovascular outcomes.In children,the cardiovascular system remains plastic and damage-reversible if early and appropriate interventions are established effectively.Therapeutic goals for NAFLD should address nutrition,physical activity,and avoidance of smoking to prevent not only end-stage liver disease but also CVD. | Lucia Pacifico Valerio Nobili Caterina Anania Paola Verdecchia Claudio Chiesa | 2011 | World Journal of Gastroenterology2011，17，26： | 24 |
| 2 | Recent cancer survival in Europe: a 2000–02 period analysis of EUROCARE-4 data显示文摘 | Arduino Verdecchia Silvia Francisci Hermann Brenner Gemma Gatta Andrea Micheli Lucia Mangone Ian Kunkler | 2007 | Lancet Oncology2007，，9： | 3 |
| 3 | Different Prognostic impact of 24 hour mean blood pressure and pulse pressure on stroke and coronary artery clisease in essential hypertension显示文摘 | Verdecchia P Schillaci G Reboldi G | 2001 | Circulation2001，103，21： | 2 |
| 4 | Relation between serum uric acid and risk of cardiovascular disease in essential hypertension 显示文摘 | Verdecchia P Schillaci G Reboldi G P | 2000 | Hypertension2000，36，6： | 1 |
| 5 | Dippers versus non-dippers显示文摘 | Schillaci G Porcellati C | 1991 | J Hypertens1991，9，8： | 1 |
| 6 | Adverse prognosticsignificance of concentric remodeling of the left ventricle in hypertensive patients with normal left ventricular mass显示文摘 | Verdecchia P Schillaci G Borgioni C | 1995 | J Am Coll Cardiol1995，25，： | 1 |
| 7 | Ambulatory pulse pressure:a potent predictor of total cardiovascular risk in hypertension显示文摘 | Verdecchia P Schillaci G Borgioni C | 1998 | Hypertension1998，32，9： | 1 |
| 8 | Blunted,nocturnal fall in blood tressure in hypertensive women with futurn cardiovascular morbid events 显示文摘 | Verdecchia P Schillaci G Gatteschi C | 1993 | circulation1993，88，3： | 1 |
| 9 | Improved electrocardiographic diagnosis of left ventricular hypertrophy显示文摘 | Schillaci G Verdecchia P Borgioni C | 1994 | Am J Cardiol1994，74，： | 1 |
| 10 | Angiotensin converting enzyme inhibitors and calcium channel blockers for coronary heart disease and stroke prevention 显示文摘 | Verdecchia P Reboldi G Angeli F | 2005 | Hypertension2005，46，2： | 1 |
| 11 | Different prognostic impact of 24 -hour mean blood pressure and pulse pressure on stroke and coronaryartery disease in essential hypertension 显示文摘 | Verdecchia P Schillaci G Reboldi G | 2001 | Circulation2001，103，21： | 1 |
| 12 | Ambulatory blood pressure and cardiovascular outcome in relation to perceived sleep deprivation显示文摘 | Verdecchia P Angeli P Borgioni C et aI | 2007 | Hypertension2007，49，： | 1 |
| 13 | Left ventricular mass and cardiovascular morbidity in essential hypertension: The MAVI Study显示文摘 | Carini G Circo A | 2001 | J Am Coll Cardiol2001，38，： | 1 |
| 14 | Different prognostic impact of 24-hour mean blood pressure and pulse pressure on stroke and coronary artery disease in essential hypertention显示文摘 | Verdecchia P Schillaci G Reboldi G | 2001 | Circulation2001，103，： | 1 |
| 15 | White-coat hypertension in adults显示文摘 | Angeli F Verdecchia P Gattobiqio R | 2005 | Blood Press Monit2005，10，6： | 1 |
| 16 | Hypertension and microalbuminuria:the new detrimental duo显示文摘 | Verdecchia P Reboldi GP | 2004 | Blood Press2004，13，： | 1 |
| 17 | Vigabatrin for tuberous sclerosis complex显示文摘 | Curatolo P Verdecchia M Bombardieri R | 2001 | Brain Dev2001，23，7： | 1 |
| 18 | New target therapies in advanced pancreatic cancer显示文摘 | Cascinu S Verdecchia L Valeri N | 2006 | Ann Oncol2006，17，5： | 1 |
| 19 | Associatio between persistent pressure overload and ventriculararrhythmias in essential hypertension显示文摘 | Schillaci G Verdecchia P Borgioni C | 1996 | Hypertens1996，28，： | 1 |
| 20 | Different prognostic impact of 24-hour mean blood pressure and pulse pressure on stroke and coronary artery disease in essential hyptension显示文摘 | Verdecchia p Schillaci G Reboldi G | 2001 | Circulation2001，103，： | 1 |
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