|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Radiomics and machine learning applications in rectal cancer:Current update and future perspectives显示文摘The high incidence of rectal cancer in both sexes makes it one of the most common tumors,with significant morbidity and mortality rates.To define the best treatment option and optimize patient outcome,several rectal cancer biological variables must be evaluated.Currently,medical imaging plays a crucial role in the characterization of this disease,and it often requires a multimodal approach.Magnetic resonance imaging is the first-choice imaging modality for local staging and restaging and can be used to detect high-risk prognostic factors.Computed tomography is widely adopted for the detection of distant metastases.However,conventional imaging has recognized limitations,and many rectal cancer characteristics remain assessable only after surgery and histopathology evaluation.There is a growing interest in artificial intelligence applications in medicine,and imaging is by no means an exception.The introduction of radiomics,which allows the extraction of quantitative features that reflect tumor heterogeneity,allows the mining of data in medical images and paved the way for the identification of potential new imaging biomarkers.To manage such a huge amount of data,the use of machine learning algorithms has been proposed.Indeed,without prior explicit programming,they can be employed to build prediction models to support clinical decision making.In this review,current applications and future perspectives of artificial intelligence in medical imaging of rectal cancer are presented,with an imaging modality-based approach and a keen eye on unsolved issues.The results are promising,but the road ahead for translation in clinical practice is rather long. | Arnaldo Stanzione Francesco Verde Valeria Romeo Francesca Boccadifuoco Pier Paolo Mainenti Simone Maurea | 2021 | World Journal of Gastroenterology2021，27，32： | 10 |
| 2 | Prunus genetics and applications after de novo genome sequencing:achievements and prospects显示文摘Prior to the availability of whole-genome sequences,our understanding of the structural and functional aspects of Prunus tree genomes was limited mostly to molecular genetic mapping of important traits and development of EST resources.With public release of the peach genome and others that followed,significant advances in our knowledge of Prunus genomes and the genetic underpinnings of important traits ensued.In this review,we highlight key achievements in Prunus genetics and breeding driven by the availability of these whole-genome sequences.Within the structural and evolutionary contexts,we summarize:(1)the current status of Prunus whole-genome sequences;(2)preliminary and ongoing work on the sequence structure and diversity of the genomes;(3)the analyses of Prunus genome evolution driven by natural and man-made selection;and(4)provide insight into haploblocking genomes as a means to define genome-scale patterns of evolution that can be leveraged for trait selection in pedigree-based Prunus tree breeding programs worldwide.Functionally,we summarize recent and ongoing work that leverages whole-genome sequences to identify and characterize genes controlling 22 agronomically important Prunus traits.These include phenology,fruit quality,allergens,disease resistance,tree architecture,and self-incompatibility.Translationally,we explore the application of sequence-based marker-assisted breeding technologies and other sequence-guided biotechnological approaches for Prunus crop improvement.Finally,we present the current status of publically available Prunus genomics and genetics data housed mainly in the Genome Database for Rosaceae(GDR)and its updated functionalities for future bioinformatics-based Prunus genetics and genomics inquiry. | Maria JoséAranzana Véronique Decroocq Elisabeth Dirlewanger Iban Eduardo Zhong Shan Gao Ksenija Gasic Amy Iezzoni Sook Jung Cameron Peace Humberto Prieto Ryutaro Tao Ignazio Verde Albert G.Abbott Pere Arús | 2019 | Horticulture Research2019，6，1： | 8 |
| 3 | Non-genomic vasorelaxant effects of 17β-estradiol and progesterone on rat aorta are mediated by L- type Ca^2+ current inhibition显示文摘 | Elisa CAIRRAO Ezequiel ALVAREZ Joao Miguel CARVAS Antonio Jose SANTOS-SILVA Ignacio VERDE | 2012 | Acta Pharmacologica Sinica2012，33，5： | 4 |
| 4 | The peach genome显示文摘 | Pere Arús Ignazio Verde Bryon Sosinski Tatyana Zhebentyayeva Albert Abbott | 2012 | Tree Genetics & Genomes2012，，3： | 3 |
| 5 | Bile duct injury during laparoscopic cholecystectomyrid=''显示文摘 | J. Calvete L. Sabater B. Camps A. Verdú A. Gomez-Portilla J. Martín M. A. Torrico B. Flor N. Cassinello S. Lledó | 2000 | Surgical Endoscopy2000，，7： | 2 |
| 6 | First Pre‐Functionalised Polymeric Aromatic Framework from Mononitrotetrakis(iodophenyl)methane and its Applications显示文摘 | Ester Verde‐Sesto Mercedes Pintado‐Sierra Avelino Corma Eva M. Maya Jose G. de la Campa Marta Iglesias Felix Sánchez | 2014 | Chem. Eur. J2014，，17： | 2 |
| 7 | Epigallocatechin-3-gallate treatment to promote neuroprotection and functional recovery after nervous system injury显示文摘Traumatic spinal cord injury(SCI)causes motor paralysis,sensory anesthesia and autonomic dysfunction below the lesion site and additionally some SCI patients refer neuropathic pain together with these signs and symptoms.Clinical and experimental studies have revealed the main pathological changes of injured spinal cord implicated in all these | Pere Boadas-Vaello Enrique Verdú | 2015 | Neural Regeneration Research2015，10，9： | 2 |
| 8 | Nerve growth factor(NGF) restores depetions of calciton in gene - related peptide and substance P in sensory neurons from diab eric mice in vetro 显示文摘 | Sango K Verdes J M Hikawa N | 2006 | J Neurol Sci2006，126，1： | 1 |
| 9 | Effect of breed on the muscle glycogen content and dark cutting incidence in stressed young bulls显示文摘 | SANZ M C VERDE M T SAEZ T | 1996 | Meat Science1996，43，1： | 1 |
| 10 | Spinal cord injury induces endoplasmic reticulum stress w ith different cell-type dependent response显示文摘 | Penas C Guzmn MS VerdúE Forés J Navarro X Casas C | 2007 | J Neurochem2007，102，4： | 1 |
| 11 | Constraints on the redshift dependence of the dark energy potential 显示文摘 | Simon J Verde L Jimenez R | 2005 | Phys Rev D2005，71，12： | 1 |
| 12 | Understandingprotein adsorption phenomena at solid surfaces显示文摘 | RABE M VERDES D SEEGER S | 2011 | Advance Colloid Interface Science2011，162，12： | 1 |
| 13 | Molecular charac- terization of isoniazid-resist ant Mycobacterium tuberculosis clinical strainsi solated in the Philippines显示文摘 | HERRER AL V AL VERDE A SAIZP | 2004 | Inl J Antimicrob Agents2004，23，6： | 1 |
| 14 | A study of Jacobians in Hardy-Orlicz spaces显示文摘 | IWANIEC T VERDE A | 1999 | Proc Roy Soc Edinburgh Sect1999，3，129： | 1 |
| 15 | A Two-Stage CMABased Receiver for Blind Joint Equalization and Multiuser Detection in High Data-Rate DS-CDMA Systems显示文摘 | Giacinto Gelli Luigi Paura Francesco Verde | 2004 | IEEE Trsnsaetions on Wireless Communications2004，3，4： | 1 |
| 16 | Efficacy of an Integrated Hospital-primary Care Program for Heart Failure: A Population-based Analysis of 56 742 Patients显示文摘 | Com in-Colet J Verd 6 -Rotellar JM Vela E | 2014 | Revista Espafiola de Cardiolog t a (English Edition)2014，67，4： | 1 |
| 17 | Transient outward currents in coclear ganglioa neurons of the ehiek embryo显示文摘 | Sheppard DN Val verde MA Represa J | 1992 | Neuroseienee1992，51，： | 1 |
| 18 | Schistosoma mansoni:Characterization of p50,an immunophilin显示文摘 | Osman A Kiang D Verde PTL | 1995 | Exp Parasitol1995，80，： | 1 |
| 19 | Isolated celiac and superior mesenteric artery dissection identified with MDCT: imaging findings and clinical course显示文摘 | Verde F Bleich KB Oshmyansky A | 2012 | J Comput Assist Tomogr2012，36，： | 1 |
| 20 | Cyclin A is required at tWo points in the human cell cycle 显示文摘 | Pagano M Pepperkok R Verde F | 1992 | EMBOJ1992，11，5： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员