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| 1 | High mobility group box protein 1 and white matter injury following traumatic brain injury: perspectives on mechanisms and therapeutic strategies显示文摘Traumatic brain injury(TBI)is a major cause of morbidity and mortality worldwide.Despite significant medical advances over recent decades,many survivors of TBI develop long term neuro-cognitive deficits.Previously,only moderate and severe injuries were thought to account for the devastating consequences of TBI.However,there is increasing evidence that even milder injuries may result in problematic lifelong cognitive and affective disturbances.TBI is typically characterized by an an acute physical injury followed by a protracted innate neuro-inflammatory response.These reponses,mediated via neuronal,astrocyte and microglial cells,amongst others,and may result in widespread neuronal death and a micro-environment that is not conducive to brain repair(Manivannan et al.,2021).Whilst the primary physical injury often evades intervention from a medical perspective,the subsequent neuro-inflammatory response offers a potential therapeutic target.Nonetheless,effective pharmacological strategies continue to elude clinicians and scientists due to the complex underlying pathogenesis and difficulties of modelling such a heterogeneous disease.However,the majority of research to date has focused on investigating the effects of post-traumatic neuro-inflammation on grey matter injury rather than the consequences upon white matter(WM),which contributes greatly to cognitive dysfunction across many neurological diseases(Filly and Kelly,2018).Herein,we will briefly discuss:(i)high mobility group box protein 1(HMGB1)as a potential therapeutic target;(ii)the relevance of WM injury in TBI and current understanding of WM repair following injury;and(iii)perspectives on how HMGB1 may play a role. | Ronak Ved Susruta Manivannan Imogen Tasker Malik Zaben | 2022 | Neural Regeneration Research2022,17,8: | 2 |
| 2 | Development and characterization of a wood adhesive using bagasse lignin 显示文摘 | Mozaffar Alam Khan Sayed Marghoob Ashraf Ved Prakash Malhotra | 2004 | International Journal of Adhesion and Adhesives2004,24,6: | 1 |
| 3 | The pharmocokinetics of propofol in children using three different analysis approaches显示文摘 | KATARIA R K VED S A NICODERNUS H F | 1994 | Anesthesioloogy1994,80,1: | 1 |
| 4 | Huperzine A, a potential therapeutic agent for dementia, reduces neuronal cell death caused by glutamate 显示文摘 | Ved H Koenig M L Dave J R | 1997 | Neuro Report1997,8,4: | 1 |
| 5 | Neonatal Hypoglycemia显示文摘 | Ved Bhushan Arya Senthil Senniappan Maria Guemes Khalid Hussain | 2014 | The Indian Journal of Pediatrics2014,,1: | 1 |
| 6 | Laparoscopic Approach to Pheochromocytoma: Is a Lower Intraabdominal Pressure Helpful?显示文摘 | Jayashree Sood Lakshmi Jayaraman Ved P. Kumra Pradeep K. Chowbey | 2006 | Anesthesia & Analgesia2006,,2: | 1 |
| 7 | Mechnaism of magnesium oxychloride formation during the hardening o{ magnesium oxychloride cement 显示文摘 | Ved E Zharov E F Phong H | 1976 | Zh Prikl Khim (Rus)1976,49,10: | 1 |
| 8 | Evaluation of vildagliptin and fixed dose combination of vildagliptin and metformin on glycemic control and insulin dose over 3 months in patients with type 2 diabetes mellitus 显示文摘 | Ved P Shah S | 2012 | Indian J Endocrinol Metab2012,16,1: | 1 |
| 9 | A dynamic ID-based remote user authentication scheme显示文摘 | Manik Lal Das Ashutosh Aaxena Ved P Gulati | 2004 | IEEE Transactions on Consumer Electronics2004,50,2: | 1 |
| 10 | The pharmacokinetics of propofol in children using three different data analysis approaches显示文摘 | Kataria BK Ved SA Nicodemus HF | 1994 | Anesthesiology1994,80,1: | 1 |
| 11 | Vascular endothelial growth factor-A165b prevents diabetic neuropathic pain and sensory neuronal degeneration 显示文摘 | Hulse RP Beazley-Long N Ved N | 2015 | Clin Sci (Lond)2015,129,8: | 1 |
| 12 | HuperzineA, a ptential therapeutic agent for dementia, reduces neuronalcell death caused by glutamate显示文摘 | Ved HS Koenig ML Dave JR | 1997 | Neuroreport1997,8,: | 1 |
| 13 | A novel remote user authentication scheme using bilinear pairings显示文摘 | Manik Lal Das Ashutosh Saxena A Ved P Gulati | 2006 | Computers & Security2006,,25: | 1 |
| 14 | Acquired Epidermoid Cysts of the Cauda Equina显示文摘 | Nica DA Strambu VED Rosca T | 2011 | Journal of Medicine and Life2011,4,3: | 1 |
| 15 | A dynamic ID-based remote user authentication scheme 显示文摘 | Manik L D Ashutosh S Ved P G | 2004 | IEEE Transac- tions on Consumer Electronics2004,50,2: | 1 |
| 16 | The effects of repeated minimal electroconvulsive shock exposure on levels of mRNA encoding fibroblast growth factor-2 and nerve growth factor in limbic regions显示文摘 | Ved R Gale K | 2002 | Neuroscience2002,114,2: | 1 |
| 17 | Development and characterization of a wood adhesive using bagasse lignin 显示文摘 | Mozaffar Alam Khan Seyed Marghoob Ashraf Ved Prakash Malhotra | 2004 | International Journal of Adhesion and Adhesives2004,24,6: | 1 |
| 18 | Synthesis,chiral chromatographic separation, and biological activities ofthe enantiomers of 10, 10-dimethylhuperzine A 显示文摘 | Rajendran V Prakash K R C Ved H S | 2000 | Bioorg Med Chem Lett2000,10,: | 1 |
| 19 | The 'good governance' concept revisited显示文摘 | Ved P.Nanda | | 0,,603: | 1 |
| 20 | Mechanism of magnesiumoxychloride formation during the hardening of magnesium oxychloridecement显示文摘 | VED E I ZHAROV E F PHONG H V | 1976 | Zh Prikl Khim1976,49,21: | 1 |