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| 1 | Predictive value of multi-detector computed tomography for accurate diagnosis of serous cystadenoma:Radiologic-pathologic correlation显示文摘AIM:To identify multi-detector computed tomography(MDCT) features most predictive of serous cystadenomas(SCAs),correlating with histopathology,and to study the impact of cyst size and MDCT technique on reader performance.METHODS:The MDCT scans of 164 patients with surgically verified pancreatic cystic lesions were reviewed by two readers to study the predictive value of various morphological features for establishing a diagnosis of SCAs.Accuracy in lesion characterization and reader conf idence were correlated with lesion size(≤3cm or≥3cm) and scanning protocols(dedicated vs routine).RESULTS:28/164 cysts(mean size,39 mm;range,8-92mm) were diagnosed as SCA on pathology.The MDCT features predictive of diagnosis of SCA were microcystic appearance(22/28,78.6%),surface lobulations(25/28,89.3%) and central scar(9/28,32.4%).Stepwise logistic regression analysis showed that only microcystic appearance was signifi cant for CT diagnosis of SCA(P=0.0001).The sensitivity,specificity and PPV of central scar and of combined microcystic appearance and lobulations were 32.4%/100%/100% and 68%/100%/100%,respectively.The reader confidence was higher for lesions>3cm(P=0.02) and for MDCT scans performed using thin collimation(1.25-2.5mm) compared to routine 5 mm collimation exams(P>0.05).CONCLUSION:Central scar on MDCT is diagnostic of SCA but is seen in only one third of SCAs.Microcystic morphology is the most significant CT feature in diagnosis of SCA.A combination of microcystic appearance and surface lobulations offers accuracy comparable to central scar with higher sensitivity. | Anjuli A Shah Nisha I Sainani Avinash Kambadakone Ramesh Zarine K Shah Vikram Deshpande Peter F Hahn Dushyant V Sahani | 2009 | World Journal of Gastroenterology2009，15，22： | 11 |
| 2 | Alcohol dehydrogenase: A potential new marker for diagnosis of intestinal ischemia using rat as a model显示文摘AIM: Intestinal ischemia (Ii) is an abdominal emergency due to blockade of the superior mesenteric artery resulting in 60-100% mortality if diagnosed late. Changes in several biochemical parameters such as D (-)-lactate, Creatinine kinase isoenzymes and lactate dehydrogenase suggested for early diagnosis, lack specificity and sensitivity. Therefore a biochemical parameter with greater sensitivity needs to be identified.METHODS: Wistar male rats were randomly assigned into two groups; control sham operated (n = 24) and ischemic test (n = 24) group. Superior mesenteric arterial occlusion was performed in the ischemic test group for 1 h. Alcohol dehydrogenase (ADH) was estimated in blood from portal vein, right ventricle of heart, dorsal aorta (DA) and inferior vena cava (IVC). The Serum glutamic acid pyruvate transaminase (SGPT) was also estimated in blood from portal vein and right ventricle of heart.RESULTS: A significant increase (P<0.001) in the levels of ADH in both portal blood as well as heart blood of the test group (232.72±99.45 EU and 250.85±95.14 EU, respectively)as compared to the control group (46.39±21.69 EU and 65.38±30.55 EU, respectively) were observed. Similarly,increased levels of ADH were observed in blood samples withdrawn from DA and IVC in test animals (319.52±80.14EU and 363.90±120.68 EU, respectively) as compared to the control group (67.68±63.22 EU and 72.50±58.45 EU,respectively). However, in test animals there was significant increase in SGPT in portal blood (P = 0.054) without much increase in heart blood.CONCLUSION: Significant increase in the levels of ADH in portal and heart blood within 1 h of SMA occlusion without increase in SGPT in heart blood, suggests that the origin of ADH is from ischemic intestine and not from liver. Similarly, raised ADH levels were found in DA and IVC as well. IVC blood does represent peripheral blood sample. A raised level of ADH in test animals confirms it to be a potential marker in the early diagnosis of Ii. | Upendra R Gumaste Mukund M Joshi Devendra T Mourya Pradip V Barde Ghanshyam K Shrivastav Vikram S Ghole | 2005 | World Journal of Gastroenterology2005，11，6： | 9 |
| 3 | Lymphoepithelial cysts and cystic lymphangiomas: Underrecognized benign cystic lesions of the pancreas显示文摘AIM: To identify their diagnostic and prognostic clinical characteristics in a large series.METHODS: Retrospective review of clinicopathologic and imaging characteristics of patients diagnosed with lymphoepithelial cysts and cystic lymphangiomas of the pancreas at Massachusetts General Hospital.RESULTS: Twelve patients were identified between 1/1/1997 and 8/1/2007. Their median age was 55.5 years(range 19-78 years), and 6 were females. The le-sion was incidentally discovered in half of the patients.Contrast enhanced computed tomography demonstrat-ed that the cysts had thin walls, without calcifications, pancreatic duct dilation or pancreatic parenchyma inva-sion. Endoscopic ultrasound with fine needle aspiration(EUS/FNA) confirmed the diagnosis of a lymphoepithe-lial cyst in 3 patients, one of whom was spared an op-eration and continues to do well after 6 years. Eleven patients had a resection: 3 pancreaticoduodenecto-mies, 7 distal pancreatectomies, and 1 enucleation. The median size of the cysts was 3 cm(range 2-20 cm). At a median follow-up of 57 mo no recurrences or other pancreas-related conditions occurred.CONCLUSION: Lymphoepithelial cysts and cystic lymphangiomas of the pancreas can be diagnosed with a combination of contrast-enhanced computed tomog-raphy scans and EUS/FNA. If the lesion is asymptom-atic, an operation might be avoided. | Ioannis T Konstantinidis Avinash Kambadakone Onofrio A Catalano Dushyant V Sahani Vikram Deshpe David G Forcione Jennifer A Wargo Carlos Fernandez-del Castillo Keith D Lillemoe Andrew L Warshaw Cristina R Ferrone | 2014 | World Journal of Gastrointestinal Surgery2014，6，7： | 2 |
| 4 | Forming of Aluminum Tailor Welded Blanks显示文摘 | Brad K Vikram V Jian C | 2001 | Journal of Materials & Manufacturing2001，10，5： | 1 |
| 5 | Foveal structure defined by spectral domain optical coherencetomography correlates with visual function after macular holesurgeiy显示文摘 | Kakarala V Ravi K Shailesh K Gupta B Vikram S Sandeep G | 2010 | Eur J Ophthalmol2010，20，3： | 1 |
| 6 | Hardware-software cosimulation of bus-based reconfigurable systems显示文摘 | VIKRAM K N VASUDENVAN V | 2005 | Microprocecessors and Microsystems2005，29，4： | 1 |
| 7 | Avian reovirus nonstructural protein μNS forms viroplasm-like inclusions and recruits protein σNS to these structures显示文摘 | Otero T F Costas M J Vikram V N | 2004 | Virology2004，319，1： | 1 |
| 8 | Low Fat Cheese Technology 显示文摘 | VIKRAM V M | 2001 | International Dairy Journal2001，11，7： | 1 |
| 9 | Low Fat Cheese Technology 显示文摘 | VIKRAM V M | 2001 | International Dairy Journal2001，，11： | 1 |
| 10 | Liquidity, investment ability, and mutual fund structure显示文摘 | Vikram N Narayanan M Warther V | 2000 | Journal of Financial Economics2000，57，41： | 1 |
| 11 | Optimal threshold policies for multiva- riate POMDPs in radar resource management显示文摘 | Vikram K Djonin D V | 2009 | IEEE Trans on Signal Processing2009，57，10： | 1 |
| 12 | Low Fat Cheese Technology显示文摘 | VIKRAM V M | 2001 | International Dairy Journal2001，11，： | 1 |
| 13 | Association between subclinical inflammation & fasting insulin in urban young adult north Indian males显示文摘 | Vikram NK Misra A Pandey RM Dwivedi M Luthra K Dh- ingra V | 2006 | Indian J Med Res2006，124，6： | 1 |
| 14 | Evaluation of Cytotoxic Effects of Bevacizumab on Human Corneal Cells显示文摘 | Kakarla V Shalam Swati Agarwal Vikram S Brar Ravi K Murthy Rajesh K Sharma | 2009 | Cornea2009，，3： | 1 |
| 15 | Mesenchymal neoplasms of the kidney in adults imaging spectrum with radiologic-pathologic correlation显示文摘 | Katabathina V S Vikram R Nagar A M | 2010 | Radiographics2010，30，15： | 1 |
| 16 | Characterization of the nucleic acid-binding activity of the avian reovirus non-structural protein sNS显示文摘 | FERNANDO T O JOSE M C VIKRAM N V | 2005 | Journal of General Virology2005，86，： | 1 |
| 17 | Rate-distortion estimation for fast JPEG 2000 compression at low bit-rates 显示文摘 | VIKRAM K N VASUDEVAN V SRINIVASAN S | 2005 | Elec Lett2005，41，1： | 1 |
| 18 | Mes- enchymal neoplasms of the kidney in adults: imagingspectrum with radiologic-pathologic correlation显示文摘 | Katabathina V S Vikram R Nagar A M | 2010 | Ra- diographics2010，30，6： | 1 |
| 19 | Experimental implementa tion of neural network springback control for sheet metal forming显示文摘 | VIKRAM V BRAD K JIAN C | 2003 | Journal of Engineering Materials and Technology2003，，： | 1 |
| 20 | Changes in Transforming Growth Faetor-l in Gingival Crevicular Fluid of Patients with Chronic Periodontitis Following Periodontal Flap Surgery显示文摘 | Vikram V Ramakrishnan T Anilkumar K | 2015 | J Clin Diagn Res2015，9，2： | 1 |
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