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| 1 | Association of smoking, alcohol drinking and dietary factors with esophageal cancer in high- and low-risk areas of Jiangsu Province, China显示文摘瞄准:到环境的 main 和在食道的癌症(EC ) 说明地区性的差别的生活方式因素在江苏省的低风险、高风险的区域冒的风险的学习,中国。方法:自从 2003,基于人口的盒子控制研究同时被进行了在低风险(Ganyu 县) 并且高风险(Dafeng 县) 江苏省的区域,中国。使用相同协议和 pre-tested 标准化了问询表,跟随写的知情同意,合格题目被询问他们 EC 的潜在的决定因素的详细信息包括人口统计的信息,社会经济的地位,生活条件,疾病历史,家庭癌症历史,吸烟,酒精喝酒,饮食的习惯,频率,食物摄取的数量,等等。有最大的可能性评价的有条件的逻辑回归被用来获得机会比率(或) 并且 95 % 信心间隔(95% CI ) ,在为潜力的调整以后,反对失败。结果:在进行中的学习的初步的分析,我们招募了在 Ganyu 的在 Dafeng 的 291 个盒子和 240 个盒子和控制分别地。在低风险、高风险的区域, EC 相反地与社会经济的地位被联系,例如教育的水平,经过经济地位和身体团索引。然而,这疾病在有癌症的家庭历史或在过去的 10 年里遇到了不幸的那些之中是更经常的。EC 在吸烟者,白酒喝酒者和快食客之中也是更经常的。而且,有在吸烟,酒精喝酒和尽管有在低风险、高风险的区域的这些风险因素的类似的流行的 EC 风险之间的协会的一个地理变化。吸烟并且吸烟的剂量反应关系联系了变量,例如首先吸烟,持续时间和数量的年龄在高风险的区域仅仅是明显的。相反,在 EC 上喝的酒精的效果上的一种剂量反应关系仅仅在低风险的区域被观察。结论:环境风险因素,可能和基因因素和基因环境的相互作用是为在江苏省的这个高风险的坡度的主要原因,中国。 | Ming Wu Jin-Kou Zhao Xiao-Shu Hu Pei-Hua Wang Yu Qin Yin-Chang Lu Jie Yang Ai-Min Liu De-Lin Wu Zuo-Feng Zhang Kok J Frans Pieter van't Veer | 2006 | World Journal of Gastroenterology2006，12，11： | 18 |
| 2 | Double balloon enteroscopy in children:Diagnosis,treatment,and safety显示文摘AIM:To assess the feasibility and utility of double balloon enteroscopy(DBE)in the management of small bowel diseases in children. METHODS:Fourteen patients(10 males)with a median age of 12.9 years(range 8.1-16.7)underwent DBE; 5 for Peutz-Jeghers syndrome(PJ syndrome),2 for chronic abdominal pain,4 for obscure gastrointestinal (GI)bleeding,2 with angiomatous malformations(1 blue rubber bleb nevus syndrome)having persistent GI bleeding,and 1 with Cowden's syndrome with multiple polyps and previous intussusception.Eleven procedures were performed under general anesthesia and 3 with deep sedation. RESULTS:The entire small bowel was examined in 6 patients,and a length between 200 cm and 320 cm distal to pylorus in the remaining 8.Seven patients had both antegrade(trans-oral)and retrograde(transanal and via ileostomy)examinations.One patient underwent DBE with planned laparoscopic assistance.The remaining 6 had trans-oral examination only.The median examination time was 118 min(range 95-195). No complications were encountered.Polyps were detected and successfully removed in all 5 patients with PJ syndrome,in a patient with tubulo-villous adenoma of the duodenum,in a patient with significant anemia and occult bleeding,and in a patient with Cowden's syndrome.A diagnosis was made in a patient with multiple angiomata not amenable to endotherapy,and in 1 with a discrete angioma which was treated with argon plasma coagulation.The source of bleeding was identified in a further patient with varices.DBE was normal or revealed minor mucosal friability in the remaining 3 patients.Hence a diagnostic yield of 11/14 with therapeutic success in 9/14 was achieved. CONCLUSION:Double balloon enteroscopy can be a useful diagnostic and therapeutic tool for small bowel disease in children,allowing endo-therapeutic intervention beyond the reach of the conventional endoscope. | Mike Thomson Krishnappa Venkatesh Khalid Elmalik Willam van der Veer Maartan Jaacobs | 2010 | World Journal of Gastroenterology2010，16，1： | 11 |
| 3 | A comprehensive review on hybrid electric vehicles: architectures and components显示文摘The rapid consumption of fossil fuel and increased environmental damage caused by it have given a strong impetus to the growth and development of fuelefficient vehicles. Hybrid electric vehicles (HEVs) have evolved from their inchoate state and are proving to be a promising solution to the serious existential problem posed to the planet earth. Not only do HEVs provide better fuel economy and lower emissions satisfying environmental legislations, but also they dampen the effect of rising fuel prices on consumers. HEVs combine the drive powers of an internal combustion engine and an electrical machine. The main components of HEVs are energy storage system, motor, bidirectional converter and maximum power point trackers (MPPT, in case of solar-powered HEVs). The performance of HEVs greatly depends on these components and its architecture. This paper presents an extensive review on essential components used in HEVs such as their architectures with advantages and disadvantages, choice of bidirectional converter to obtain high efficiency, combining ultracapacitor with battery to extend the battery life, traction motors’ role and their suitability for a particular application. Inclusion of photovoltaic cell in HEVs is a fairly new concept and has been discussed in detail. Various MPPT techniques used for solar-driven HEVs are also discussed in this paper with their suitability. | Krishna Veer Singh Hari Om Bansal Dheerendra Singh | 2019 | Journal of Modern Transportation2019，27，2： | 8 |
| 4 | Double balloon endoscopy associated pancreatitis:A description of six cases显示文摘AIM:To perform a single-center analysis of all double balloon endoscopy (DBE) related cases of pancreatitis identified prospectively from a recorded DBE-complication database. METHODS:From November 2003 until January 2007, 603 DBE procedures were performed on 412 patients, with data on complications recorded in a database. The setting was a tertiary care center offering DBE. DBE was performed from the antegrade or retrograde route. Out-come measurements included age, gender, medication, indication, DBE-endoscope type, insertion depth, proce-dure duration, findings, interventions, post-procedural abdominal pain, and post-procedural hospitalization. RESULTS:This is the largest single-center study report-ing on post-DBE pancreatitis prospectively. Six patients (1.0%) developed post-DBE pancreatitis, all after antegrade DBE. There was no association with gender, duration of the procedure or type of endoscope. The mean age was 51.9 years (range 25-78). Four patients had severe pancreatitis. Of these, two had inflammatory signs in the body-tail region, one had pancreatitis in the tail region, and the total pancreas was involved in one. CONCLUSION:The incidence of post-DBE pancreatitis in our series is higher than previously reported. We found no relation with DBE-endoscope type. The inflammatory changes occurred in the body-tail region of the pancreas, suggesting that post-DBE pancreatitis is caused by repetitive mechanical strain on the pancreas. | Soeresh VA Jarbandhan Stijn JB van Weyenberg Willem M van der Veer Dimitri GN Heine Chris JJ Mulder Maarten AJM Jacobs | 2008 | World Journal of Gastroenterology2008，14，5： | 8 |
| 5 | Recent advances in molecular diagnostics of hepatitis Bvirus显示文摘Hepatitis B virus(HBV)is one of the important global health problems today.Infection with HBV can lead to a variety of clinical manifestations including severe hepatic complications like liver cirrhosis and hepatocellular carcinoma.Presently,routine HBV screening and diagnosis is primarily based on the immuno-detection of HBV surface antigen(HBsAg).However,identification of HBV DNA positive cases,who do not have detectable HBsAg has greatly encouraged the use of nucleic acid amplification based assays,that are highly sensitive,specific and are to some extent tolerant to sequence variation.In the last few years,the field of HBV molecular diagnostics has evolved rapidly with advancements in the molecular biology tools,such as polymerase chain reaction(PCR)and real-time PCR.Recently,apart of PCR based amplification methods,a number of isothermal amplification assays,such as loop mediated isothermal amplification,transcription mediated amplification,ligase chain reaction,and rolling circle amplification have been utilized for HBV diag-nosis.These assays also offer options for real time detection and integration into biosensing devices.In this manuscript,we review the molecular technologies that are presently available for HBV diagnostics,with special emphasis on isothermal amplification based technologies.We have also included the recent trends in the development of biosensors and use of next generation sequencing technologies for HBV. | Sibnarayan Datta Soumya Chatterjee Vijay Veer Molecular Virology Laboratory | 2014 | World Journal of Gastroenterology2014，20，40： | 6 |
| 6 | Molecular Biology of the Hepatitis B Virus for Clinicians显示文摘 | Sibnarayan Datta Soumya Chatterjee Vijay Veer Runu Chakravarty | 2012 | Journal of Clinical and Experimental Hepatology2012，，4： | 5 |
| 7 | Next-generation sequencing in clinical virology: Discovery of new viruses显示文摘Viruses are a cause of significant health problem world-wide, especially in the developing nations. Due to different anthropological activities, human populations are exposed to different viral pathogens, many of which emerge as outbreaks. In such situations, discovery of novel viruses is utmost important for deciding prevention and treatment strategies. Since last century, a number of different virus discovery methods, based on cell culture inoculation, sequence-independent PCR have been used for identification of a variety of viruses. However, the recent emergence and commercial availability of nextgeneration sequencers(NGS) has entirely changed the field of virus discovery. These massively parallel sequencing platforms can sequence a mixture of genetic materials from a very heterogeneous mix, with high sensitivity. Moreover, these platforms work in a sequenceindependent manner, making them ideal tools for virus discovery. However, for their application in clinics, sample preparation or enrichment is necessary to detect low abundance virus populations. A number of techniques have also been developed for enrichment or viral nucleic acids. In this manuscript, we review the evolution of sequencing; NGS technologies available today as well as widely used virus enrichment technologies. We also discuss the challenges associated with their applications in the clinical virus discovery. | Sibnarayan Datta Raghvendra Budhauliya Bidisha Das Soumya Chatterjee Vanlalhmuaka Vijay Veer | 2015 | World Journal of Virology2015，4，3： | 5 |
| 8 | 热带地区相对湿度的季节性变化影响果蝇Drosophila jambulina体色多型性和水分平衡(英文)显示文摘在印度次大陆的亚热带地区,秋天冷而干燥,春天湿润。变温性果蝇所具有的抗干燥性有助于其度过较为干旱的气候条件。Drosophila jambulina具有体色二型性。已有研究表明,随湿度变化,D.jambulina热带种群始终保持体色多型性,这与热条件下体色黑化相反,且该热带物种中体色分化频率随季节性变化,这符合黑化-干燥假说。但是两种色型的D.jambulina产生这类气候适应的机理尚不明了。为了检验干燥相关性状生理基础的分化与对气候条件的色型特异性适应相关这一假说,我们利用分别在17℃和25℃、低湿(40%RH)和高湿(80%RH)条件下饲养获得的两种色型的D.jambulina,检测了其水分平衡对相对湿度、温度、及温湿度相互作用的反应。我们发现,在低相对湿度下,两种温度下饲养的深色型果蝇的生理和脱水性状数值显著高于浅色型。对两种色型果蝇的水分收支情况进行的比较分析表明,在低相对湿度下,深色型果蝇的含水量较高、水分损失率较低、抗脱水能力较强,使其具有更强的抗干燥性。在干燥胁迫过程中,两种色型的果蝇均以碳水化合物作为代谢燃料,但是在低湿条件下,深色果蝇中贮存碳水化合物的含量明显要高。而且,在两种湿度条件下,这两种色型果蝇之间的总能量收支显著不同。据此认为,D.jambulina的水分平衡相关性状表现出的色型特异性分化与其对湿热生境的适应相关。 | Ekta KHASA Parul BADHWAR Veer BHAN | 2013 | 昆虫学报2013，56，12： | 3 |
| 9 | Socio-economic determinants for malaria transmission risk in an endemic primary health centre in Assam, India显示文摘Background:Malaria is a major cause of morbidity and mortality in Northeast India.As there is limited information available on the potential influence of socio-economic variables on malaria risk,the present study was conducted to assess the influence of demographic factors,the socio-economic status,and knowledge,awareness and education on malaria occurrence.Methods:Demographics,malaria knowledge and socio-economic variables were collected in four randomly selected health sub-centres of the Orang primary health centre in the Udalguri district,Assam and the association of malaria occurrence with different variables were analysed.The trend of malaria occurrence for different income groups,proximity to health centres and number of mosquito bites per day was also determined using the chi-square test.Relative risk(RR)for gender,house type,knowledge and use of bed nets was determined using Katz approximation.Results:Out of the 71 household heads interviewed,70.4%(50/71)were males.About half(54.9%,39/71)of the participants had a history of malaria in the last two years,of which 64.1%(25/39)were males,while 35.9%(14/39)were females(χ^(2)=5.13;p=0.02;RR=1.79).Of the total population surveyed,49.3%lived in bamboo houses and 35.2%lived at a distance of>3 km from the nearest health centre.The number of participants who had a history of malaria decreased with an increasing monthly income(p<0.0001).Malaria occurrence was higher among the households living in bamboo houses(69.2%),as compared to Kucha houses(20.5%)and Pucca houses(10.3%).No significant association was observed between education level and malaria occurrence(p=0.93).The participants who did not use bed nets regularly reported a high occurrence of malaria infection as compared to those who used bed nets everyday(p<0.0001).Conclusions:Lower income,house type,distance to health sub-centre,knowledge and awareness about malaria,number of mosquito bites per day and use of bed nets were positively associated with malaria occurrence.Increasing the number of health sub-centres close to rural areas,improving the economic status and increasing awareness about malaria prevention measures will thus help to reduce malaria-associated morbidities. | Kavita Yadav Sunil Dhiman Bipul Rabha PK Saikia Vijay Veer | 2014 | Infectious Diseases of Poverty2014，3，1： | 3 |
| 10 | Exploring single atom catalysts of transition-metal doped phosphorus carbide monolayer for HER:A first-principles study显示文摘Hydrogen has been identified as one of the most promising sustainable and clean energy. Developing hydrogen evolution reaction(HER) catalyst with high activity is essential for satisfying the future requirements. Considering novel advantages of two-dimensional materials and high catalytic activity of atomic transition metal, in this study, using density functional theory calculation, the HER on single transitionmetal(23 different TM atoms) doped phosphorus carbide monolayer(α-PC) has been investigated. The Volmer–Tafel and Volmer–Heyrovsky reaction mechanisms, and the stability of the most promising HER catalyst are also included. The results show that Ir-αPC with high physical and thermal stability has the most optimal value of Gibbs free adsorption energy for H atom. The relationship of d band center and the HER activity shows a volcano-like curve. The calculation of reaction energy barrier indicates that the Volmer-Heyrovsky step is more favorable than the Volmer-Tafel step. | Dachang Chen Zhiwen Chen Xiaoxing Zhang Zhuole Lu Song Xiao Beibei Xiao Chandra Veer Singh | 2021 | Journal of Energy Chemistry2021，30，1： | 3 |
| 11 | 调控超细高熵合金晶格应变用于高活性和高稳定性甲醇氧化显示文摘高熵合金(HEAs)因其非常规的组成和独特的物理化学性质而得到广泛研究.本文,我们首次提出了一种表面应变策略来调控HEAs的电子结构用于高效的甲醇电氧化反应(MOR).高分辨像差校正扫描透射电子显微镜(STEM)和元素分布分析表明,在Pt Fe CoNi Cu HEAs中各原子分散均匀,并形成FCC晶体结构.700℃热处理所得HEA-700的压缩应变比400℃热处理所得HEA-400的压缩应变高0.94%.正如预期,HEA-700的比活性和质量活性远超HEA-400和目前大多数最先进的催化剂.MOR活性的增强归因于压缩应变导致HEA-700中Pt–Pt键距缩短.同时,核中的非贵金属原子通过转移电子到表面Pt层产生压缩应变和d带中心的下移.这项工作为高性能HEAs电催化剂的设计提供了一个新的视角. | 王东东 陈志文 黃裕呈 李巍 王娟 卢琢乐 顾开智 王特华 吴雨洁 陈晨 张怡琼 黄小青 陶李 董崇禮 陈俊 Chandra Veer Singh 王双印 | 2021 | Science China Materials2021，64，10： | 3 |
| 12 | High cardiovascular risk in severely obese young children and adolescents显示文摘 | Nathalie M A van Emmerik Carry M Renders Marije van de Veer Stef van Buuren Olga H van der Baan-Slootweg Joana E Kist-van Holthe Remy A HiraSing | 2012 | Archives of Disease in Childhood2012，，9： | 2 |
| 13 | 文献快报(5):肥胖者大脑食物奖赏和突显网络功能连接存在特异性显示文摘肥胖是当前公认的严重公共卫生问题,主要由于能量摄入过多所致。能量摄入的多少是内部因素(如内环境稳态调节信号与情绪认知状态)和外部因素(食物与社会环境的可获得性)共同作用的结果,大脑通过整合多种激素和神经信号对“吃”的行为起着至关重要的作用。 | WIJNGAARDEN MA VEER IM ROMBOUTS SA 苏普玉 | 2015 | 中国学校卫生2015，36，4： | 2 |
| 14 | Fractional Flow Reserve Versus Angiography for Guiding Percutaneous Coronary Intervention in Patients With Multivessel Coronary Artery Disease显示文摘 | Nico H.J. Pijls William F. Fearon Pim A.L. Tonino Uwe Siebert Fumiaki Ikeno Bernhard Bornschein Marcel van't Veer Volker Klauss Ganesh Manoharan Thomas Engstr?m Keith G. Oldroyd Peter N. Ver Lee Philip A. MacCarthy Bernard De Bruyne | 2010 | Journal of the American College of Cardiology2010，，3： | 2 |
| 15 | Complement pathway in Alzheimer’s pathology and retinal neurodegenerative disorders–the road ahead显示文摘Chronic inflammation has increasingly been acknowledged as a hallmark feature of several progressive neurodegenerative disorders. Accruing evidence indicates that sustained inflammation compromises the core neuroprotective mechanisms underlying neural injury in Alzheimer's disease (AD) and retinal neurodegenerative disorders. | Mehdi Mirzaei Liting Deng Veer Bala Gupta Stuart Graham Vivek Gupta | 2020 | Neural Regeneration Research2020，15，2： | 2 |
| 16 | Expression profile and function of triggering receptor expressed on myeloid cells-1 during melioidosis显示文摘 | Wiersinga WJ Veer CT Wieland CW | 2007 | J Infect Dis2007，196，11： | 1 |
| 17 | Gene expression profiling predicts clinical outcome of breast cancer 显示文摘 | van't Veer L J Dai H van de Vijver M J | 2002 | Nature2002，415，6871： | 1 |
| 18 | A gene-expression signature as a predictor of survival in breast cancer显示文摘 | van de Vijver MJ He YD van't Veer LJ | 2002 | N Engl j Med2002，347，25： | 1 |
| 19 | Study of onychomycosis: prevailing fungi and pattern of infection显示文摘 | Veer P Patwardhan NS Damle AS | 2007 | Indian J Med Mi- crobiol2007，25，1： | 1 |
| 20 | Effect of the factor V Leiden mutation on the incidence and outcome of severe infection and sepsis 显示文摘 | Marcel Schouten C Van't Veer T Van Der Poll | 2012 | Neth J Med2012，70，7： | 1 |
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