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15篇 您的检索式:作者名="V Pot"
    题名 作者 年代 出处 被引量
1Correlation between in vitro and in vivo immunomodulatory properties of lactic acid bacteria显示文摘AIM: To investigate the correlation between in vitro and in vivo immunomodulation potential of the probiotic strain and its ability to prevent experimental colitis in mice. METHODS: In vitro immunomodulation was assessed by measuring interleukin (IL)-12p70, IL-10, tumor necrosis factor alpha (TNFa) and interferon g (IFNg) release by human peripheral blood mononuclear cells (PBMCs) after 24 h stimulation with 13 live bacterial strains. A murine model of acute TNBS-colitis was next used to evaluate the prophylactic protective capacity of the same set of strains. RESULTS: A strain-specific in vivo protection was observed. The strains displaying an in vitro potential to induce higher levels of the anti-inflammatory cytokine IL-10 and lower levels of the inflammatory cytokine IL-12, offered the best protection in the in vivo colitis model. In contrast, strains leading to a low IL-10/IL-12 cytokine ratio could not significantly attenuate colitis symptoms. CONCLUSION: These results show that we could predict the in vivo protective capacity of the studied lactic acid bacteria (LAB) based on the cytokine profile we established in vitro. The PBMC-based assay we used may thus serve as a useful primary indicator to narrow down the number of candidate strains to be tested inmurine models for their anti-inflammatory potential.Benoit Foligne Sophie Nutten Corinne Grangette Véronique Dennin Denise Goudercourt Sabine Poiret Joelle Dewulf Dominique Brassart Annick Mercenier Bruno Pot 2007World Journal of Gastroenterology2007,13,2:22
2AFLP:a new technique for DNA fingerprinting显示文摘VOS P HOGERS R BLEEKER M REIJANS M LEE T V D HORNES M FRITERS A POT J PALEMAN J KUIPER M ZABEAU M 1995Nu-cleic Acids Research1995,23,21:1
3Evaluating equilibrium and non --equilibrium transport of bromide and is oproturon in disturbed and undisturbed soil columns 显示文摘S Dousset M Thevenot V Pot 2007Journal of Contaminant Hydrology2007,,94:1
4Anti-inflammatory potential of the probiotic dietary supplement Lactibiane Tolérance: In vitro and in vivo considerations显示文摘Sophie Drouault-Holowacz Beno?t Foligné Véronique Dennin Denise Goudercourt Kathleen Terpend André Burckel Bruno Pot 2006Clinical Nutrition2006,,6:1
5Impact of rainfall intensity on the transport of two herbicides in undisturbed grassed filter strip soil cores显示文摘Pot V ?im?nek J Benoit P 2005Journal of Contaminant Hydrology2005,81,1:1
6Importance of bacterial storage polymers in bioprocess显示文摘Loosdrecht V Pot MAM Heijnen JJ 1997Water Sci Technol1997,35,:1
7Effect of learning on the oviposition preference of field-collected and laboratory-reared Chilo partellus(Lepidoptera:Crambidae)populations显示文摘GLAS J J BERG J V POTTING R P J 2007Bulletin of Entomological Research2007,97,:1
8Apomorphine-induced eosinophilic panniculitis and hypereosinophilia in Parkinson disease显示文摘Pot C Oppliger R Castillo V 2005Neurology2005,64,:1
9Type 1 regulatory T cells ( Trl ) in autoimmunity 显示文摘Pot C Apetoh L Kuchroo V K 2011Semin Immunol2011,23,3:1
10The Impact of Public R&D Expenditure on Business R&D 显示文摘GUELLEC D POT]?ELSBERGHE V B 2003Economics of Innovation and New Technology2003,,12:1
11Have European stocks become more volatile? an empirical investigation of idiosyncratic and market risk in the Euro Area显示文摘Kearney C Potì V 0,,03:1
12Impact of rainfall intensity on the transport of two herbicides in undisturbed grassed filter strip soil cores 显示文摘Pot V Simunek J Benoit P 2005Journal of Contaminant Hydrology2005,81,:1
13Kinetic modeling of poly (-hydroxybutyrate) production and consumption by paracoccus pantotrophus under dynamic substrate supply 显示文摘AALST VAN M A POT M A LOOSDRECHT M V 1997Biotechnology and Bioengineering1997,55,:1
14Self- assembling hydrogels based on β- cyclodextrin/cholesterol inclusion complexes 显示文摘DE MANAKKER F V DER POT M V TINA V 2008Macromolecules2008,41,:1
15Numerical calculation of effective diffusion in unsaturated porous media by the TRT Lattice Boltzmann Method 显示文摘Genty A Pot V 2014Transport in porous media2014,105,2:1
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