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| 1 | 海藻糖对冷冻鱼面冻融稳定性的影响显示文摘为提高冷冻鱼面的品质,研究海藻糖对冷冻鱼面冻融稳定性的影响。采用质构仪研究了海藻糖对冻融循环过程中冷冻鱼面品质的影响,采用低场核磁共振测定了冷冻鱼面冻融过程中水分迁移、分布状态,研究了海藻糖改善冷冻鱼面冻融稳定性的机制。结果显示,添加2%海藻糖(m/m)使鱼面的拉断力从110.7 g提高到133.9 g;反复冻融4次后空白鱼面拉断力降低了35.0 g,添加2%海藻糖(m/m)鱼面的拉断力降低了21.1 g,其拉断力仍与新鲜空白对照鱼面的拉断力相当;海藻糖可以调整鱼面中水分状态,使结合水含量增加,自由水含量减少;海藻糖还能有效抑制水分从表面向鱼面芯部迁移,因此有利于保留鱼面'筋道'的口感。综上,海藻糖可显著改善冷冻鱼面的冻融稳定性,最佳添加量是2%。 | 刘薇丛 金丽 付湘晋 TYRE Lanier 杨迎洁 | 2017 | 食品科学2017，38，1： | 11 |
| 2 | 依那西普对银屑病患者疲劳和抑郁症状的临床疗效:一项双盲、随机、安慰剂对照、III期试验显示文摘Background: Psoriasis has substantial psychological and emotional effects. We assessed the effect of etanercept, an effective treatment for the clinical symptoms of psoriasis, on fatigue and symptoms of depression associated with the condition. Methods: 618 patients with moderate to severe psoriasis received double-blind treatment with placebo or 50 mg twice-weekly etanercept. The primary efficacy endpoint was a 75% or greater improvement from baseline in psoriasis area and severity index score (PASI 75) at week 12. Secondary and other endpoints included the functional assessment of chronic illness therapy fatigue (FACIT-F) scale, the Hamilton rating scale for depression (Ham-D), the Beck depression inventory (BDI), and adverse events. Efficacy analyses were based on the allocated treatment. Analyses and summaries of safety data were based on the actual treatment received. This study is registered with ClinicalTrials.gov with the identifier NCT00111449. Findings: 47% (147 of 311) of patients achieved PASI 75 at week 12, compared with 5% (15 of 306) of those receiving placebo (p< 0.0001; difference 42% , 95% CI 36- 48). Greater proportions of patients receiving etanercept had at least a 50% improvement in Ham-D or BDI at week 12 compared with the placebo group; patients treated with etanercept also had significant and clinically meaningful improvements in fatigue (mean FACIT-F improvement 5.0 vs 1.9; p< 0.0001, difference 3.0, 95% CI 1.6- 4.5). Improvements in fatigue were correlated with decreasing joint pain, whereas improvements in symptoms of depression were less correlated with objective measures of skin clearance or joint pain. Interpretation: Etanercept treatment might relieve fatigue and symptoms of depression associated with this chronic disease. | Tyring S. Gottlieb A. Papp K. R. Krishnan 王琼(译) | 2006 | 世界核心医学期刊文摘(皮肤病学分册)2006，2，3： | 4 |
| 3 | 一种新的鱼体分割方式对白鲢鱼鱼糜鱼糕品质的影响显示文摘提出一种新的鱼体分割方式:从肋骨与脊骨连接处切开,把鱼体分割成腹部和背部两部分,比较了白鲢鱼腹部鱼肉与背部鱼肉鱼糜鱼糕品质。结果表明,背部鱼肉加工的鱼糜凝胶强度显著高于腹部鱼肉鱼糜(P<0.05),60℃保温处理使腹部鱼肉鱼糕凝胶强度下降更多;但两种鱼糕的白度、保水性没有显著差异;加热模式相同时,腹部鱼肉鱼糜鱼糕肽含量、总-巯基含量高于背部鱼肉鱼糜鱼糕;十二烷基硫酸钠-变性凝胶电泳(sodium dodecyl sulfatepolyacrylamide gel electrophoresis,SDS-PAGE)表明,背部鱼肉鱼糜胶凝过程中发生了更多交联。 | 徐莉娜 贺海翔 付湘晋 TYRE Lanier 程瑶 陈梦玲 丁玉琴 | 2018 | 食品研究与开发2018，39，12： | 3 |
| 4 | Dual mechanism of action of ingenol mebutate gel for topical treatment of actinic keratoses: Rapid lesion necrosis followed by lesion-specific immune response显示文摘 | Robert H. Rosen Aditya K. Gupta Stephen K. Tyring | 2011 | Journal of the American Academy of Dermatology2011，，： | 2 |
| 5 | 鱼糜中活泼羰基化合物在胶凝过程中的变化显示文摘本文采用五氟苯肼原位衍生化-固相微萃取-气相/质谱法检测了鲢鱼鱼糜、冷冻鱼糜及鱼糜凝胶中的三种活泼羰基化合物(RCCs):丙二醛(MDA)、4-羟基-己烯醛(HHE)、4-羟基-壬烯醛(HNE);并采用添加五氟苯肼清除RCCs,阻断RCCs-蛋白质反应,分析鱼糜中RCCs对鱼糜蛋白胶凝特性的影响。结果表明:新鲜鲢鱼糜中MDA(0.42±0.02)mg/kg、HHE(0.21±0.03)mg/kg含量高于HNE(0.07±0.00)mg/kg;冷冻鱼糜RCCs含量高于新鲜鱼糜,MDA、HHE、HNE含量分别为(1.14±0.03)、(0.86±0.03)、(0.18±0.02)mg/kg。新鲜鱼糜加热胶凝后,各RCC含量均显著上升(p<0.05),冷冻鱼糜加热胶凝后,各RCC含量均显著(p<0.05)下降;添加RCCs清除剂阻断RCCs-蛋白质反应后,冷冻鱼糜凝胶(40℃1 h-90℃30 min)强度从(243.52±25.04)g×cm下降到(190.53±20.33)g×cm(p<0.05);所以,RCCs加强了冷冻鱼糜凝胶的强度。RCCs对鱼糜凝胶的保水性无明显影响。 | 付湘晋 刘颖 李忠海 林亲录 Tyre C. Lanier | 2017 | 食品工业科技2017，38，10： | 2 |
| 6 | Vulnerability of Xylem to Cavitation and Embolism显示文摘 | Tyree M T Sperry J S | 1989 | Ann Rev Plant Physiol Plant Molecular Bio1989，40，： | 1 |
| 7 | Patients with condyloma acuminatum exhibit decreased IL - 2 and interferon - gamma production and depressed natural killer activity显示文摘 | Canda R Tyring SK Grossi CE | 1987 | J Clin Immunol1987，7，： | 1 |
| 8 | Water relations and hydraulic architecture of a tropical tree (Schefflera morototoni)显示文摘 | Tyree M T Snyderman D A | 1991 | Plant Physiol1991，96，： | 1 |
| 9 | Human papillomaviruses and genital disease显示文摘 | Ahmed AM Madkan V Tyring SK | 2006 | Dermatol Clin2006，24，2： | 1 |
| 10 | Patients with condyloma acuminata exhibit decreased interleukin-2 and interferon gamma production and depressed natural killer activity显示文摘 | Cauda R Tyring S K Grossi C E | | 0，，： | 1 |
| 11 | Management of herpes zoster and postherpetic neuralgia显示文摘 | Tyring SK | | 0，，6： | 1 |
| 12 | Patients with condyloma acuminatum exhibit decreased interleukin -2 and interferon gamma production and depressed natural killer activity 显示文摘 | Cauda R Tyring SK Grossi CE | 1987 | J Clin Immunol1987，，4： | 1 |
| 13 | Cutaneous manifestations of Epstein-Barr virus infection显示文摘 | IKEDIOBI NI TYRING SK | 2002 | Dermatol Clin2002，20，2： | 1 |
| 14 | PIP1 plasma membrane aquaporins in tobacco:from cellular effects to function in plants显示文摘 | Siefritz F Tyree M T Lovisolo C | 2002 | The Plant Cell2002，14，4： | 1 |
| 15 | Do woody plants operate near the print of catastrophic xylem dysfunction cansed by dynamic water stress?显示文摘 | TYREE M T SPERRY J S | 1988 | Plant Physiology1988，88，： | 1 |
| 16 | Changes in root hydraulic conductance(KR) of Olea oleaster seedlings following drought stress and irrigation显示文摘 | Gullo M I Nardini A Salleo S Tyree M | 1998 | New physiology1998，140，： | 1 |
| 17 | Safety and immunogenicity of glycoprotein D-adjuvant genital herpes vaccine 显示文摘 | Bemstein D I Aoki F Y Tyring S K | 2005 | Clin Infect Dis2005，40，9： | 1 |
| 18 | Antimicrobial susceptibility of Propionibacterium acrtes isolates from ache patients in Colombia 显示文摘 | Mendoza N Hemandez PO Tyring SK | 2013 | Int J Dermatol2013，52，6： | 1 |
| 19 | A Randomized, Double-Blind, Placebo-Controlled Dose Range Study of Dexmedetomidine as Adjunctive Therapy for Alcohol Withdrawal*显示文摘 | Scott W. Mueller Candice R. Preslaski Tyree H. Kiser Douglas N. Fish James C. Lavelle Stephen P. Malkoski Robert MacLaren | 2014 | Critical Care Medicine2014，，5： | 1 |
| 20 | Cytomegalovirus infections显示文摘 | Khoshnevis M Tyring SK | 2002 | Dermatol Clin2002，20，2： | 1 |
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