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| 1 | Biomarkers in inflammatory bowel diseases:Current status and proteomics identification strategies显示文摘Unambiguous diagnosis of the two main forms of inflammatory bowel diseases(IBD):Ulcerative colitis(UC)and Crohn’s disease(CD),represents a challenge in the early stages of the diseases.The diagnosis may be established several years after the debut of symptoms.Hence,protein biomarkers for early and accurate diagnostic could help clinicians improve treatment of the individual patients.Moreover,the biomarkers could aid physicians to predict disease courses and in this way,identify patients in need of intensive treatment.Patients with low risk of disease flares may avoid treatment with medications with the concomitant risk of adverse events.In addition,identification of disease and course specific biomarker profiles can be used to identify biological pathways involved in the disease development and treatment.Knowledge of disease mechanisms in general can lead to improved future development of preventive and treatment strategies.Thus,the clinical use of a panel of biomarkers represents a diagnostic and prognostic tool of potentially great value.The technological development in recent years within proteomic research(determination and quantification of the complete protein content)has made the discovery of novel biomarkers feasible.Several IBD-associated protein biomarkers are known,but none have been successfully implemented in daily use to distinguish CD and UC patients.The intestinal tissue remains an obvious place to search for novel biomarkers,which blood,urine or stool later can be screened for.When considering the protein complexity encountered in intestinal biopsysamples and the recent development within the field of mass spectrometry driven quantitative proteomics,a more thorough and accurate biomarker discovery endeavor could today be performed than ever before.In this review,we report the current status of the proteomics IBD biomarkers and discuss various emerging proteomic strategies for identifying and characterizing novel biomarkers,as well as suggesting future targets for analysis. | Tue Bennike Svend Birkelund Allan Stensballe Vibeke Andersen | 2014 | World Journal of Gastroenterology2014，20，12： | 9 |
| 2 | 镍钼杂多酸制备NiMo/γ-Al_2O_3催化剂及硼、钴或镍改性氧化铝的影响(英文)显示文摘A hydrotreating NiMo/γ-Al2O3 catalyst(12 wt% Mo and 1.1 wt% Ni) was prepared by impregnation of the support with the Anderson-type heteropolyoxomolybdate(NH4)4Ni(OH)6Mo6O18.Before impregnation of the support,it was modified with an aqueous solution of H3BO3,Co(NO3)2,or Ni(NO3)2.The catalysts were investigated using N2 adsorption,O2 chemisorption,X-ray diffraction,UV-Vis spectroscopy,Fourier transform infrared spectroscopy,temperature-programmed reduction,temperature-programmed desorption,and X-ray photoelectron spectroscopy.The addition of Co,Ni,or B influenced the Al2O3 phase composition and gave increased catalytic activity for 1-benzothiophene hydrodesulfurization(HDS).X-ray photoelectron spectroscopy confirmed that the prior loading of Ni,Co or B increased the degree of sulfidation of the NiMo/γ-Al2O3 catalysts.The highest HDS activity was observed with the NiMo/γ-Al2O3 catalyst with prior loaded Ni. | Radostina PALCHEVA Luděk KALUZA Alla SPOJAKINA Květue JIRTOV Georgi TYULIEV | 2012 | 催化学报2012，33，6： | 6 |
| 3 | Occurrence of emerging flame retardants from e-waste recycling activities in the northern part of Vietnam显示文摘This study investigated the contamination status of 21 emerging flame retardants(FRs)in soils(n=32)and river sediments(n=8)from an e-waste recycling(EWR)site in the northern part of Vietnam.Among analyzed FRs,higher levels of decabromodiphenyl ethane(DBDPE)(NDe4200 ng/g dw),1,2-bis-(2,4,6-tribromophenoxy)ethane(BTBPE)(NDe350 ng/g dw)and Dechlorane Plus isomers(DPs)(NDe65 ng/g dw)were found in soils near EWR workshops and open burning places.The highest concentrations of DBDPE(20 ng/g dw),BTBPE(5.7 ng/g dw)and DPs(6.7 ng/g dw)were also detected in sediments collected from the middle of the EWR site.The levels decreased concomitantly with increasing distance from the EWR site.These results indicate that these FRs were released to the surrounding environment from improper recycling activities,such as manual dismantling of devices and open burning of e-wastes.Moreover,the estimated daily intakes of those FRs via soil ingestion were approximately ten times higher for children than adults.To our knowledge,this is a first comprehensive study on characterization of soil and sediment contamination by a series of emerging FRs at an EWR site in Vietnam. | Masayuki Someya Go Suzuki Alin C.Ionas Nguyen Minh Tue Fuchao Xu Hidenori Matsukami Adrian Covaci Le Huu Tuyen Pham Hung Viet Shin Takahashi Shinsuke Tanabe Hidetaka Takigami | 2016 | Emerging Contaminants2016，2，2： | 5 |
| 4 | Analysis of monomeric and oligomeric organophosphorus flame retardants in fish muscle tissues using liquid chromatographyeelectrospray ionization tandem mass spectrometry:Application to Nile tilapia(Oreochromis niloticus)from an e-waste processing area in northern Vietnam显示文摘Using electrospray ionization tandem mass spectrometry combined with liquid chromatography(LC),a novel analytical method was developed to quantify eight monomeric organophosphorus flame retardants(m-PFRs)and three oligomeric organophosphorus flame retardants(o-PFRs)in fish muscle samples.The optimization and validation experiments indicate that the developed method can determine accurately the concentrations of analytes in fish muscle samples.The recoveries of analytes in fish muscle samples were in the range of 74-105%.The coefficients of variation of the concentrations of analytes in fish muscle samples were 0.6-8.9%.The concentrations of analytes in procedural blanks were below the limit of quantification(LOQ)values.Furthermore,the developed method was applied to the analysis of m-PFRs and o-PFRs in the muscle samples of tilapias collected from an electronic waste(ewaste)processing area in northern Vietnam.The concentrations of m-PFRs such as tris(2-chloroethyl)phosphate(TCEP),tris(2-chloroisopropyl)phosphate(TCIPP),and triphenyl phosphate(TPHP)were dominant among the investigated m-PFRs.The respective concentrations of TCEP,TCIPP,and TPHP were up to 160,300,and 230 ng g^-1 lipid weight,respectively,whereas those of o-PFRs were up to 10 ng g^-1 lipid weight.The results of this study indicate lower accumulation potential of o-PFRs compared with m-PFRs for the first time. | Hidenori Matsukami Go Suzuki Nguyen Minh Tue Le Huu Tuyen Pham Hung Viet Shin Takahashi Shinsuke Tanabe Hidetaka Takigami | 2016 | Emerging Contaminants2016，2，2： | 5 |
| 5 | An investigation of brain processes supporting meditation显示文摘 | Klaus B. B?rentsen Hans St?dkilde-J?rgensen Bo Sommerlund Tue Hartmann Johannes Damsgaard-Madsen Mark Fosn?s Anders C. Green | | Cognitive Processing0，，： | 1 |
| 6 | Empirical Ship Domain based on AIS Data显示文摘 | Martin Gamborg Hansen Toke Koldborg Jensen Tue Lehn-Schi?ler Kristina Melchild Finn M?lsted Rasmussen Finn Ennemark | 2013 | Journal of Navigation2013，，6： | 1 |
| 7 | Effect of lifestyle, gender and age on collagen formation and degradation显示文摘 | Lars Tue S?rensen | 2006 | Hernia2006，，6： | 1 |
| 8 | Comprehensive evaluation of dioxins and dioxin-like compounds in surface soils and river sediments from e-waste-processing sites in a village in northern Vietnam:Heading towards the environmentally sound management of e-waste显示文摘The management of electronic waste(e-waste),which can be a source of both useful materials and toxic substances,depending on the processing method,is important for promoting material cycling.In this study,we used the dioxin-responsive chemical-activated luciferase gene expression(DR-CALUX)assay combined with gas chromatographyehigh-resolution mass spectrometry to evaluate the levels of dioxin-like compounds in surface soils and river sediments collected in and around an e-waste-processing village in northern Vietnam.The WHO-TEQs(Toxic equivalents)of polychlorinated dibenzo-p-dioxins and dibenzofurans(PCDD/Fs),coplanar polychlorinated biphenyls(Co-PCBs),and polybrominated dibenzo-pdioxins and dibenzofurans(PBDD/Fs)in soils collected in January 2012 ranged from 0.29 to 310 pg/g(median 2.9 pg/g,n=32),and the WHO-TEQs in sediments ranged from 0.96 to 58 pg/g(median 4.4 pg/g,n=8).Dioxin-like activities(CALUX-TEQs[2,3,7,8-TCDD equivalent])in soils collected in January 2012,2013,and 2014 ranged from<30 to 4300 pg/g(median<30 pg/g,n=96),and the activities in sediments ranged from<30 to 4000 pg/g(median 33 pg/g,n=24).Dioxin-like compounds accumulated in samples collected around e-waste-processing areas such as open-burning sites and e-waste-processing workshops,and the compounds may be transported from their sources to surrounding areas over the course of several years.Some of the CALUX-TEQs,but not WHO-TEQs,values were higher than the maximum acceptable WHO-TEQs promulgated by various authorities,indicating that all dioxin-like compounds should be evaluated in samples collected from e-waste-processing areas.Our findings suggest that open burning and open storage of e-waste should be prohibited and that wastewater treatment should be implemented at each workshop to reduce contamination by dioxin-like compounds from e-waste. | Go Suzuki Masayuki Someya Hidenori Matsukami Nguyen Minh Tue Natsuyo Uchida Le Huu Tuyen Pham Hung Viet Shin Takahashi Shinsuke Tanabe Abraham Brouwer Hidetaka Takigami | 2016 | Emerging Contaminants2016，2，2： | 1 |
| 9 | Improvement in the corrosion resistance of magnesium ZK60SiC composite by exeimer laser surface treatment 显示文摘 | Tue T M Wang A H Man H C | 1998 | Sempta Mater1998，38，19： | 1 |
| 10 | Separation performance of sub-micron silica particles by electrical hydrocyclone显示文摘 | Romanus Krisantus Tue Nenu Hideto Yoshida Kunihiro Fukui Tetsuya Yamamoto | 2009 | Powder Technology2009，，2： | 1 |
| 11 | Evaluation of dioxin-like activities in settled house dust from Vietnamese E-waste recycling sites: Relevance of polychlorinated/brominated dibenzo-p-dioxin/furans and dioxin-like PCBs 显示文摘 | Tue Nguyen M Suzuki Go Ttakahshi Shin | 2010 | Environ Sci Technol2010，44，： | 1 |
| 12 | Contamination of indoor dust and air by polychlorinated biphenyls and brominated flame retardants and relevance of non-dietary exposure in Vietnamese informal e- waste recycling sites 显示文摘 | Tue NM Takahashi S Suzuki G | 2013 | Environ Int2013，51，： | 1 |
| 13 | Carbon storage of a tropical mangrove forest in Mui Ca Mau National Park, Vietnam 显示文摘 | TUE NT DUNG LV NHUAN MT 2014 | 2014 | Catena2014，121，： | 1 |
| 14 | Chemical stability of chlortetracycline and chlortetracycline degradation products and epimers in soil interstitial water显示文摘 | Tue Soeborg Flemming Ingerslev Bent Halling-Sφrensen | 2004 | Chemosphere2004，57，10： | 1 |
| 15 | Discovery of technical methanation catalysts based on computational screening显示文摘 | Jens Sehested Kasper Emil Larsen Arkady L. Kustov Anne Mette Frey Tue Johannessen Thomas Bligaard Martin P. Andersson Jens K. N?rskov Claus Hviid Christensen | 2007 | Topics in Catalysis (-)2007，，1： | 1 |
| 16 | Improvement in the corrosion resistance of magnesium ZK60SiC composite by excimer laser surface treatment显示文摘 | Tue T M Wang A H Man H C | 1998 | Scmpta Mater1998，38，2： | 1 |
| 17 | The application ofδ13C and C/N ratios as indicators of organic carbon sources and palaeoenvironmental change of the mangrove ecosystem from Ba Lat Estuary,Red River,Vietnam显示文摘 | Tue N T Hamaoka H Sogabe A | 2011 | Environmental Earth Sciences2011，64，5： | 1 |
| 18 | Contamination of indoor dust and air by polychlorinated biphenyls and brominated flame retardants and relevance of non-dietary exposure in Vietnamese informal e-waste recycling sites显示文摘 | Tue N M Takahashi S Suzuki G | 2013 | Environment International2013，51，： | 1 |
| 19 | Efficient algorithm for training interpolation RBF net- works with equally spaced nodes 显示文摘 | Hoang Xuan Huan Dang Thi Thu Hien Huynh Huu Tue | 2011 | Neural Networks IEEE Transactions on2011，22，6： | 1 |
| 20 | 越南7个不同荔枝品种果实品质分析比较(摘要)(英文)显示文摘[目的]筛选出适合越南当地生产的荔枝品种。[方法]分别对引种至越南农科院北部山区农林研究所内栽培的7个不同荔枝的果实植物学性状和品种果实品质性状进行了比较分析。[结果]在供试品种中,适宜当地栽培综合品质性状优良荔枝品种有LaiPhuHo、ThachBinh、HungLong;PhuDong为可利用的早熟种植资源。[结论]该研究可为越南北部山区荔枝生产、育种提供参考。 | 张晓芳 刘光华 罗心平 黄家雄 吕玉兰 娄予强 Nguyen Dinh Tue Tran Mihn Hoa | 2010 | Agricultural Science & Technology2010，11，8： | 1 |
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