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| 1 | Optimizing outcomes for patients with gastric cancer peritoneal carcinomatosis显示文摘Peritoneal carcinomatosis (PC) from gastric cancer has traditionally been considered a terminal progression of the disease and is associated with poor survival out-comes. Positive peritoneal cytology similarly worsens the survival of patients with gastric cancer and treatment options for these patients have been limited. Recent ad-vances in multimodality treatment regimens have led to innovative ways to care for and treat patients with this disease burden. One of these advances has been to use neoadjuvant therapy to try and convert patients with positivecytologyorlow-volume PC to negative cytolo-gy with no evidence of active peritoneal disease.These strategies include the use of neoadjuvant systemic chemotherapy alone,using neoadjuvant laparoscopic heated intraper itoneal chemotherapy(NLHIPEC)after systemic chemotherapy,or using neoadjuvant intra-peritoneal and systemic chemother apy(NIPS)in a bi-dir ectional manner. For patients with higher volume PC,cytoreductive surgery (CRS) and hyperthermic intrape-ritoneal chemotherapy(HIPEC)have been mainstays of treatment. When used together, CRS and HIPEC can improve overall outcomes in properly selected patients,but overall survival outcomes remain unacceptably low.The extent of peritoneal disease, commonly measured by the peritoneal carcinomatosis index (PCI), and the com-pleteness of cytor eduction,has been shown to greatly impact outcomes in patients undergoing CRS and HIPEC.The uses of NLHIPEC and NLHIPEC plus NIPS have both been shown to decrease the PCI and thus increase the opportunity for complete cytoreduction. Newer therapies like pressurized intraperitoneal aerosol chemother apy and immunotherapy, such as catumaxomab, along with improved systemic chemotherapeutic regimens, are being explored with great interest.There is exciting progress being made in the management of PC from gastric can-cer and its’ treatment is no longer futile. | Jennifer L Leiting Travis E Grotz | 2018 | World Journal of Gastrointestinal Oncology2018，10，10： | 4 |
| 2 | Anatomically realistic multiscale models of normal and abnormal gastrointestinal electrical activity显示文摘One of the major aims of the International Union of Physiological Sciences (IUPS) Physiome Project is to develop multiscale mathematical and computer models that can be used to help understand human health. We present here a small facet of this broad plan that applies to the gastrointestinal system. Specifically, we present an anatomically and physiologically based modelling framework that is capable of simulating normal and pathological electrical activity within the stomach and small intestine. The continuum models used within this framework have been created using anatomical information derived from common medical imaging modalities and data from the Visible Human Project. These models explicitly incorporate the various smooth muscle layers and networks of interstitial cells of Cajal (ICC) that are known to exist within the walls of the stomach and small bowel. Electrical activity within individual ICCs and smooth muscle cells is simulated using a previously published simplified representation of the cell level electrical activity. This simulated cell level activity is incorporated into a bidomain representation of the tissue, allowing electrical activity of the entire stomach or intestine to be simulated in the anatomically derived models. This electrical modelling framework successfully replicates many of the qualitative features of the slow wave activity within the stomach and intestine and has also been used to investigate activity associated with functional uncoupling of the stomach. | Leo K Cheng Rie Komuro Travis M Austin Martin L Buist Andrew J Pullan | 2007 | World Journal of Gastroenterology2007，13，9： | 3 |
| 3 | The second European evidence-based Consensus on the diagnosis and management of Crohn’s disease: Current management显示文摘 | A. Dignass G. Van Assche J.O. Lindsay M. Lémann J. S?derholm J.F. Colombel S. Danese A. D’Hoore M. Gassull F. Gomollón D.W. Hommes P. Michetti C. O’Morain T. ?resland A. Windsor E.F. Stange S.P.L. Travis | 2010 | Journal of Crohn’s and Colitis2010，，1： | 2 |
| 4 | Differential effect of amino acids on nitrate uptake and reduction systems in barley roots显示文摘 | Muhammad Aslam Robert L Travis D.William Rains | 2001 | Plant Science2001，，2： | 2 |
| 5 | European evidence-based Consensus on the management of ulcerative colitis: Current management显示文摘 | S.P.L. Travis E.F. Stange M. Lémann T. ?resland W.A. Bemelman Y. Chowers J.F. Colombel G. D'Haens S. Ghosh P. Marteau W. Kruis N.J.McC. Mortensen F. Penninckx M. Gassull | 2008 | Journal of Crohn’s and Colitis2008，，1： | 2 |
| 6 | Comparative kinetics and reciprocal inhibition of nitrate and nitrate in roots of uninduced and induced barley seedlings显示文摘 | ASLAN M TRAVIS R L HUFFAKER R C | 1992 | Plant Physiology1992，99，： | 1 |
| 7 | Expression of surfactant associ-ated protein-A and Clara cell 10 kilodahon mRNA in neoplastic and non-neoplastichuman lung tissue as detected by in situ hybridization 显示文摘 | Broers J L Jensen S M Travis W D | 1992 | Lab Invest1992，66，3： | 1 |
| 8 | European evidence based consensus on the diagnosis and management of Crohn's disease:current management显示文摘 | Travis SPL Stange E F Lémann M | 2006 | Gut2006，55，： | 1 |
| 9 | Cushing syndrome due to primary pigmented nodular adrenocortical disease:findings at CT and MR imaging显示文摘 | Doppman J L Travis W D Nieman L | 1989 | Radiology1989，172，2： | 1 |
| 10 | Lung cancer 显示文摘 | Travis W D Travis L B Devesa S S | 1995 | Cancer1995，75，1： | 1 |
| 11 | Knowledge discovery in medical and biological datasets using a hybrid Bayes classifier/evolutiomry algorithm 显示文摘 | Michael L Raymer Travis E | 2003 | IEEE Tmnsactiom on Systems Man and Cybernetics2003，2003，2： | 1 |
| 12 | A survey of sorption relationships for reactive solutes in soil显示文摘 | Travis C C Etnier E L | 1981 | Journal of Environmental Quality1981，10，1： | 1 |
| 13 | Estimation of the spatial distribu- tion of target cells for radiation pneumonitis in mouse lung 显示文摘 | Tucker S L Liao Z X Travis E L | 1997 | Int J Radiat Oncol Biol Phys1997，38，5： | 1 |
| 14 | Lung cancer 显示文摘 | Travis W D Travis L B Devesa S S | 1995 | Cancer1995，75，1： | 1 |
| 15 | Characterization of a pollen-specific cDNA clone from Zea mays and its expression 显示文摘 | Hanson D D Hamilton D A Travis J L | 1989 | Plant Cell1989，1，2： | 1 |
| 16 | Mechanisms of therapy- related carcino genesis显示文摘 | Allan J M Travis L B | 2005 | Nat RevCancer2005，5，12： | 1 |
| 17 | Differential effect of amino acid on nitrate uptake and reduction systems in barley roots显示文摘 | Aslam M Travis R L Rains D W | 2001 | Plant Science2001，160，： | 1 |
| 18 | Fibroblast radiosensitivity in vitro and lung fibrosis in vivo: Comparison between a fibrosis- prone and fibrosis-resistant mouse strain 显示文摘 | Dileto C L Travis E L | 1996 | Radiation Research1996，146，： | 1 |
| 19 | Guidelines for themanagement of inflammatory bowel disease in adults显示文摘 | Carter M J Lobo A J Travis S P L | 2004 | Gut2004，53，9： | 1 |
| 20 | Incidence patterns of soft tissue sarcomas, regardless of primary site,in the surveillance, epidemiology and end results program, 1978-2001:An analysis of 26,758 cases显示文摘 | Toro J R Travis L B Wu H J | 2006 | Int J Cancer2006，119，12： | 1 |
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