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| 1 | Aspartate transaminase to platelet ratio index in hepatitis C virus and Schistosomiasis coinfection显示文摘AIM: To assess the diagnostic accuracy,of aminotransferase-to-platelet ratio index(APRI) alone and with antischistosomal antibody(Ab) in patients with hepatitis C virus(HCV) and schistosomiasis coinfection. METHODS: This retrospective study included medical records of three hundred and eighty three Egyptianmen patients who had undergone percutaneous liver biopsy between January 2006 to April 2014 in tertiary care hospital in Qatar for diagnosis or monitoring purpose were selected. Data of patients > 18 years of age were included in the study. The values of HCV RNA titer and antischistosomal antibody titer were also taken into consideration. Patients were excluded from the study if they had any other concomitant chronic liver disease,including; history of previous antiviral or interferon therapy,immunosuppressive,therapy,chronic hepatitis B infection,human immunodeficiency virus co-infection,autoimmune hepatitis,decompensated liver disease,hepatocellular carcinoma,prior liver transplantation,and if no data about the liver biopsy present. RESULTS: Median age of patients was 46 years. About 7.1% had no fibrosis,whereas 30.4%,37.5%,20.4%,and 4.6% had fibrosis of stage Ⅰ,Ⅱ,Ⅲ,and Ⅳ respectively. In bivariate analysis,APRI score,levels of AST,platelet count and age of patient showed statistically significant association with liver fibrosis(P < 0.0001); whereas antischistosomal antibody titer(P = 0.52) and HCV RNA titer(P = 0.79) failed to show a significant association. The respective AUC values for no fibrosis,significant fibrosis,severe fibrosis and cirrhosis of APRI score were 63%,73.2%,81.1% and 88.9% respectively. This showed good sensitivity and specificity of APRI alone for grading of liver fibrosis. But the inclusion of anti-Schistosoma antibody did not improve the prediction of fibrosis stage. CONCLUSION: The study results suggest that noninvasive biochemical markers like APRI are sensitive and specific in diagnosing the degree of fibrosis and cirrhosis in patients with coinfection of HCV and schistosomiasis as compared to biopsy. The addition of antischistosomal Ab to APRI did not improve sensitivity for predicting the degree of cirrhosis. | Moutaz Derbala Mohammed Elshiekh Elbadri Aliaa Mohamed Amer Saad Al Kaabi Khaleel Hassan Sultan Yasser Medhat Kamel Eman Hassan Satti Elsayed Tony Yervant Avades Prem Chandra Fatma M Shebl | 2015 | World Journal of Gastroenterology2015，21，46： | 2 |
| 2 | The Novel mTOR Inhibitor RAD001 (Everolimus) Induces Antiproliferative Effects in Human Pancreatic Neuroendocrine Tumor Cells 显示文摘 | Zitzmann K De Toni EN Brand S et al | 2007 | Neuroendocrinology2007，85，1： | 1 |
| 3 | Parent-child interaction therapy with behavior problem children : relative effectiveness of two stages and overall treatment outcome 显示文摘 | Toni Hembree Eisenstadt Sheila Eyberg Cheryl Bodiford McNeil et al | 1993 | J Clinical Child Psychology1993，22，1： | 1 |
| 4 | Treatment Modalities for Subtrochanteric Fractures in the Elderly显示文摘 | Toni MM Ericka AL | 2004 | Techniques in Orthopaedics2004，19，3： | 1 |
| 5 | Parent-child interaction therapy with behavior problem children: generalization of treatment effects to the school setting 显示文摘 | Cheryl Bodiford McNeil Sheila Eyberg Toni Hembree Eisenstadt et al | 1991 | J Clinical child Psychology1991，20，2： | 1 |
| 6 | Polyethylene multiwalled carbon nanotube composites显示文摘 | Tony McNally Petra P/tschke Peter Halley et aL | 2005 | Polymer2005，46，： | 1 |
| 7 | Faculty attitudes towards medical communication and their perceptions of students' cormunication skills training at Dalhousie University显示文摘 | Donald BL David MK Toni AL Heather M | 2001 | Medical Education2001，35，： | 1 |
| 8 | Modelling urban stormwater treatment-A unified approach显示文摘 | TONY H F WONG T D FLETCHER H P el al | 2006 | Ecological Engineering2006，27，： | 1 |
| 9 | Effects of fermentation on antioxidant properties and phytochemical composition of soy germ显示文摘 | SHEIH 1-Chuan TONY J Fang WU Tung Kung el al | 2014 | Journal of The Science of Food and Agriculture2014，94，15： | 1 |
| 10 | Cholesterol lowering with bile salt hydrolase-active probiotic bac- teria, mechanism of action, clinical evidence, and future direction for heart health applications 显示文摘 | JONES M L TOMARO-DUCHESNEAU C MAP TONI C J et al | 2013 | Expert Opinion on Biological Therapy2013，13，5： | 1 |
| 11 | Trees as hotspots:Using forests,trees,and agroforestry to foster diverse sustainable landscapes显示文摘Forests,trees,and agroforestry(FTA)are ecosystem hotspots.They exemplify the contributions of biodiversity to sustainable and resilient landscapes,green circular economy and to sustainable agriculture and food systems for healthy diets.However,most research on these topics have been performed separately and lack comparison.The International FTA-Kunming Conference'Forests,trees and agroforestry for diverse sustainable landscapes'22nd–24th June 2021,focused on these contributions,brought together scientists NGOs,and policy makers to further the understanding of tree diversity;provided a communication platform for scientists to share their research results;evaluated the role of tree diversity in agroecology and circular agriculture;assessed benefits of landscape restoration;and explored applied research in mountain ecosystems and food security.The goals were to gather evidence that ground the design of solutions that can contribute to the implementation of the post 2020 Global Biodiversity Framework and towards the UN Food Systems Summit,and the overall implementation of the SDGs.This paper summarizes the outcomes of the international FTA Conference in Kunming 2021 and points out the highlights of research involved in six major themes. | Vincent Gitz Jianchu Xu Yuanchang Lu Elaine Springgay Illias Animon Razan Khalifa Al Mubarak Robert Nasi Tony Simons Ranjit Barthakur Ren Wang Jianrong Su Fergus Sinclair Eduardo Somarriba Dossa G.O.Gbadamassi Ramni Jamnadass Christopher JKettle Dengpan Bu Anja Gassner Yves Laumonier Mi Zhou Himlal Baral Fangyuan Hua Peter AMinang Yufu Guo Michael Allen Brady Yanxia Li Peter Mortimer Bin Yang Heng Gui Fiona Worthy Deli Zhai Huafang Chen Huili Li Yufang Su Alexandre Meybeck Fabio Ricci | 2022 | Circular Agricultural Systems2022，2，1： | 0 |
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