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242篇 您的检索式：作者名="Tohno"

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	题名	作者	年代	出处	被引量
1	Molecular Cloning and Functional Characterization of Porcine MyD88 Essential for TLR Signaling显示文摘We isolated cDNA encoding porcine MyD88 (poMyD88) from Peyer's patches (Pps) of GALT. The complete open reading frame (ORF) of poMyD88 contains 879 bp encoding a deduced 293 aa residues. The amino acid sequence of poMyD88 was characterized by N-terminal death,intermediate and C-terminal Toll/IL-1 receptor (TIR) domains. The putative poMyD88 protein shares a higher level of homology with its human (87.2% amino acid identity) than with its mouse (77.4% amino acid identity) counterpart. Overexpression of poMyD88 participated in the further enhanced activation of NF-κB in human embryonic kidney (HEK) 293 cells expressing porcine TLR2 and porcine TLR4/MD-2,but not porcine RP105/MD-1 after stimulation with the corresponding ligands. The expression levels of MyD88 were highest in the spleen and mesenteric lymph nodes (MLNs),and lower in digestive tissues of newborn swine. In adult swine,the expression levels in the digestive tissues were lower than those in MLNs and the spleen. These results suggest that an MyD88-dependent signaling pathway is present in newborn as well as in adult swine and that it is involved in the innate immune system of these animals.	Masanori Tohno Tomoyuki Shimazu Hisashi Aso Yasushi Kawai Tadao Saito Haruki Kitazawa	2007	Cellular & Molecular Immunology2007，4，5：	20
2	Breast disease:clinical application of US elastography for diagnosis显示文摘	Itoh A Ueno E Tohno E	2006	Radiology2006，239，：	1
3	Breast disease:clinical application of US elastography for diagnosis显示文摘	Itoh A Ueno E Tohno E	2006	Radiology2006，239，2：	1
4	An ultrasonographic method for detection of Achilles tendon xanthomas in familial hypercholesterolemia 显示文摘	Yuzawa K Yanakawa K Tohno E	1989	Atherosclerosis1989，75，4：	1
5	Breast disease: clinical application of US elastography for diagnosis 显示文摘	Itoh A Ueno E Tohno E	2006	Radiology2006，239，2：	1
6	Breast disease:clinical app lication of US elastography for diagnosis显示文摘	Itoh A Ueno E Tohno E	2006	Radiologr120062006，，：	1
7	Breast Disease : Clinical Application of US Elastography for Diagnosis 显示文摘	Itoh A Ueno E Tohno E	2006	Radiology2006，239，2：	1
8	Breast disease : clinicalapplication of US elastography for diagnosis 显示文摘	Itoh A Ueno E Tohno E	2006	Radiology2006，239，2：	1
9	Utilization of the Porcine System to Study Lymphotoxin-β Regulation in Intestinal Lymphoid Tissue显示文摘	Tomoyuki Shimazu Masanori Tohno Shinichiro Katoh Takeshi Shimosato Hisashi Aso Yasushi Kawai Tadao Saito Haruki Kitazawa	2009	Biochemical Genetics2009，，：	1
10	Breast disease:clinical application of US elastography for diagnosis显示文摘	Itoh A Ueno E Tohno E	2006	Radiology2006，239，2：	1
11	Breast disease:clinical application of US elastography for diagnosis显示文摘	Itoh A Ueno E Tohno E	2006	Radiology2006，239，2：	1
12	Breast disease: clinical application of US elastography for diagnosis显示文摘	hoh A Ueno E Tohno E	2006	Radiology2006，239，2：	1
13	Toll-like receptor 4 and cytokine expression involved in functional immune response in an originally established porcine intestinal epitheliocyte cell line显示文摘	Moue M Tohno M Shimazu T	2008	Biochimica et Biophysica Acta(BBA)-General Subjects2008，1780，2：	1
14	Breast disease: clinical application of US elastography for diagnosis 显示文摘	hoh A Ueno E Tohno E	2006	Radiology2006，239，2：	1
15	Breast disease: clinical application of US Elastography for diagnosis显示文摘	Itoh A Ueno E Tohno E	2006	Radiology2006，239，2：	1
16	Breast disease: clinical application ofUS elastography for diagnosis显示文摘	Itoh A Ueno E Tohno E	2006	Radiology2006，239，2：	1
17	Breast disease:clinical application of US elastography for diagnosis 显示文摘	Itoh A Ueno E Tohno E	2006	Radiology2006，239，2：	1
18	Breast disease:clinical application of US elastography for diagnosis显示文摘	Itoh A Ueno E Tohno E		0，，2：	1
19	Breast disease: clinical application of US elastography for diagnosis显示文摘	ltoh A Ueno E Tohno E	2006	Radiology2006，239，2：	1
20	Breast disease, clinical ap- plication of US elastography for diagnosis 显示文摘	Itoh A Ueno E Tohno E	2006	Radiology2006，239，：	1

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